Introducing ALZET?ew Model 2006 Pump Sign up for PNAS Online eTocs
Link: Info for AuthorsLink: Editorial BoardLink: AboutLink: SubscribeLink: AdvertiseLink: ContactLink: Sitemap Link: PNAS Home
Proceedings of the National Academy of Sciences
Link: Current Issue "" Link: Archives "" Link: Online Submission ""  Link: Advanced Search

Published online on July 28, 2003, 10.1073/pnas.1533499100
PNAS | August 5, 2003 | vol. 100 | no. 16 | 9388-9393


This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Supporting Information
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a colleague
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My File Cabinet
Right arrow Download to citation manager
Right arrow Request Copyright Permission
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via ISI Web of Science (98)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gil, R.
Right arrow Articles by Moya, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gil, R.
Right arrow Articles by Moya, A.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg  
What's this?

 Previous Article  | Table of Contents |  Next Article 

EVOLUTION
The genome sequence of Blochmannia floridanus: Comparative analysis of reduced genomes

Rosario Gil *, Francisco J. Silva *, Evelyn Zientz {dagger}, François Delmotte * {ddagger}, Fernando González-Candelas *, Amparo Latorre *, Carolina Rausell * §, Judith Kamerbeek ¶ ||, Jürgen Gadau **, Bert Hölldobler **, Roeland C. H. J. van Ham ¶ {dagger}{dagger}, Roy Gross {dagger}, and Andrés Moya * {ddagger}{ddagger}

*Institut Cavanilles de Biodiversitat i Biologia Evolutiva, Universitat de València, Apartat Oficial 2085, 46071 Valencia, Spain; {dagger}Lehrstuhl für Mikrobiologie and **Lehrstuhl für Soziobiologie und Verhaltensphysiologie, Biozentrum der Universität Würzburg, Am Hubland, 97074 Würzburg, Germany; and Centro de Astrobiología, Instituto Nacional de Técnica Aeroespacial–Consejo Superior de Investigaciones Científicas, Carretera de Ajalvir kilómetro 4, 28850 Torrejón de Ardoz, Madrid, Spain

Contributed by Bert Hölldobler, June 6, 2003

Bacterial symbioses are widespread among insects, probably being one of the key factors of their evolutionary success. We present the complete genome sequence of Blochmannia floridanus, the primary endosymbiont of carpenter ants. Although these ants feed on a complex diet, this symbiosis very likely has a nutritional basis: Blochmannia is able to supply nitrogen and sulfur compounds to the host while it takes advantage of the host metabolic machinery. Remarkably, these bacteria lack all known genes involved in replication initiation (dnaA, priA, and recA). The phylogenetic analysis of a set of conserved protein-coding genes shows that Bl. floridanus is phylogenetically related to Buchnera aphidicola and Wigglesworthia glossinidia, the other endosymbiotic bacteria whose complete genomes have been sequenced so far. Comparative analysis of the five known genomes from insect endosymbiotic bacteria reveals they share only 313 genes, a number that may be close to the minimum gene set necessary to sustain endosymbiotic life.

Data deposition: The sequences reported in this paper have been deposited in the GenBank/EMBL/DDBJ database (accession no. BX248583).

{ddagger} Present address: Institut National de la Recherche Agronomique, Domaine de la Grande Ferrade, 33883 Villenave d'Ornon Cedex, France.

§ Present address: Instituto de Biotecnología, Universidad Nacional Autónoma de México. Apartado Postal 510-3, Cuernavaca 62250, Morelos, Mexico.

|| Present address: Keygene N. V., P.O. Box 216, 6700 AE Wageningen, The Netherlands.

{dagger}{dagger} Present address: Plant Research International B. V., Business Unit Genomics, N. V., P.O. Box16, 6700 AA Wageningen, The Netherlands.

{ddagger}{ddagger} To whom correspondence should be addressed. E-mail: andres.moya{at}uv.es.


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg    What's this?


This article has been cited by other articles in HighWire Press-hosted journals:


Home page
 Proc. Natl. Acad. Sci. USAHome page
N. Ruiz, L. S. Gronenberg, D. Kahne, and T. J. Silhavy
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli
PNAS, April 8, 2008; 105(14): 5537 - 5542.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
Y. Hongoh, V. K. Sharma, T. Prakash, S. Noda, T. D. Taylor, T. Kudo, Y. Sakaki, A. Toyoda, M. Hattori, and M. Ohkuma
Complete genome of the uncultured Termite Group 1 bacteria in a single host protist cell
PNAS, April 8, 2008; 105(14): 5555 - 5560.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
J. P. McCutcheon and N. A. Moran
Parallel genomic evolution and metabolic interdependence in an ancient symbiosis
PNAS, December 4, 2007; 104(49): 19392 - 19397.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
J. Collier, H. H. McAdams, and L. Shapiro
A DNA methylation ratchet governs progression through a bacterial cell cycle
PNAS, October 23, 2007; 104(43): 17111 - 17116.
[Abstract] [Full Text] [PDF]

Home page
 Genome Res.Home page
L. Gomez-Valero, E. P.C. Rocha, A. Latorre, and F. J. Silva
Reconstructing the ancestor of Mycobacterium leprae: The dynamics of gene loss and genome reduction
Genome Res., August 1, 2007; 17(8): 1178 - 1185.
[Abstract] [Full Text] [PDF]

Home page
 J. Bacteriol.Home page
A. J. Clark, M. Pontes, T. Jones, and C. Dale
A Possible Heterodimeric Prophage-Like Element in the Genome of the Insect Endosymbiont Sodalis glossinidius
J. Bacteriol., April 1, 2007; 189(7): 2949 - 2951.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
F. J. Silva, E. Belda, and S. E. Talens
Differential annotation of tRNA genes with anticodon CAT in bacterial genomes
Nucleic Acids Res., November 6, 2006; 34(20): 6015 - 6022.
[Abstract] [Full Text] [PDF]

Home page
 Appl. Environ. Microbiol.Home page
C. Anselme, A. Vallier, S. Balmand, M.-O. Fauvarque, and A. Heddi
Host PGRP Gene Expression and Bacterial Release in Endosymbiosis of the Weevil Sitophilus zeamais.
Appl. Envir. Microbiol., October 1, 2006; 72(10): 6766 - 6772.
[Abstract] [Full Text] [PDF]

Home page
 Appl. Environ. Microbiol.Home page
E. Zientz, I. Beyaert, R. Gross, and H. Feldhaar
Relevance of the Endosymbiosis of Blochmannia floridanus and Carpenter Ants at Different Stages of the Life Cycle of the Host
Appl. Envir. Microbiol., September 1, 2006; 72(9): 6027 - 6033.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
L. Klasson and S. G. E. Andersson
Strong Asymmetric Mutation Bias in Endosymbiont Genomes Coincide with Loss of Genes for Replication Restart Pathways
Mol. Biol. Evol., May 1, 2006; 23(5): 1031 - 1039.
[Abstract] [Full Text] [PDF]

Home page
 J Exp BotHome page
A. E. Douglas
Phloem-sap feeding by animals: problems and solutions
J. Exp. Bot., March 1, 2006; 57(4): 747 - 754.
[Abstract] [Full Text] [PDF]

Home page
 BioinformaticsHome page
M. D. Prickett, M. Page, A. E. Douglas, and G. H. Thomas
BuchneraBASE: a post-genomic resource for Buchnera sp. APS
Bioinformatics, March 1, 2006; 22(5): 641 - 642.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
L. Baldo, S. Bordenstein, J. J. Wernegreen, and J. H. Werren
Widespread Recombination Throughout Wolbachia Genomes
Mol. Biol. Evol., February 1, 2006; 23(2): 437 - 449.
[Abstract] [Full Text] [PDF]

Home page
 Appl. Environ. Microbiol.Home page
J. A. Russell and N. A. Moran
Horizontal Transfer of Bacterial Symbionts: Heritability and Fitness Effects in a Novel Aphid Host
Appl. Envir. Microbiol., December 1, 2005; 71(12): 7987 - 7994.
[Abstract] [Full Text] [PDF]

Home page
 Appl. Environ. Microbiol.Home page
N. A. Moran, P. Tran, and N. M. Gerardo
Symbiosis and Insect Diversification: an Ancient Symbiont of Sap-Feeding Insects from the Bacterial Phylum Bacteroidetes
Appl. Envir. Microbiol., December 1, 2005; 71(12): 8802 - 8810.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
N. A. Moran, P. H. Degnan, S. R. Santos, H. E. Dunbar, and H. Ochman
Inaugural Article: The players in a mutualistic symbiosis: Insects, bacteria, viruses, and virulence genes
PNAS, November 22, 2005; 102(47): 16919 - 16926.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
H. Ochman
Genomes on the shrink
PNAS, August 23, 2005; 102(34): 11959 - 11960.
[Full Text] [PDF]

Home page
 J. Bacteriol.Home page
A. K. Chikova and R. M. Schaaper
The Bacteriophage P1 hot Gene Product Can Substitute for the Escherichia coli DNA Polymerase III {theta} Subunit
J. Bacteriol., August 15, 2005; 187(16): 5528 - 5536.
[Abstract] [Full Text] [PDF]

Home page
 Genome Res.Home page
P. H. Degnan, A. B. Lazarus, and J. J. Wernegreen
Genome sequence of Blochmannia pennsylvanicus indicates parallel evolutionary trends among bacterial mutualists of insects
Genome Res., August 1, 2005; 15(8): 1023 - 1033.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
E. Belda, A. Moya, and F. J. Silva
Genome Rearrangement Distances and Gene Order Phylogeny in {gamma}-Proteobacteria
Mol. Biol. Evol., June 1, 2005; 22(6): 1456 - 1467.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
A. Nakabachi, S. Shigenobu, N. Sakazume, T. Shiraki, Y. Hayashizaki, P. Carninci, H. Ishikawa, T. Kudo, and T. Fukatsu
Transcriptome analysis of the aphid bacteriocyte, the symbiotic host cell that harbors an endocellular mutualistic bacterium, Buchnera
PNAS, April 12, 2005; 102(15): 5477 - 5482.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
J. T. Herbeck, P. H. Degnan, and J. J. Wernegreen
Nonhomogeneous Model of Sequence Evolution Indicates Independent Origins of Primary Endosymbionts Within the Enterobacteriales ({gamma}-Proteobacteria)
Mol. Biol. Evol., March 1, 2005; 22(3): 520 - 532.
[Abstract] [Full Text] [PDF]

Home page
 Microbiol. Mol. Biol. Rev.Home page
E. Zientz, T. Dandekar, and R. Gross
Metabolic Interdependence of Obligate Intracellular Bacteria and Their Insect Hosts
Microbiol. Mol. Biol. Rev., December 1, 2004; 68(4): 745 - 770.
[Abstract] [Full Text] [PDF]

Home page
 Genome Res.Home page
E. Lerat and H. Ochman
{Psi}-{Phi}: Exploring the outer limits of bacterial pseudogenes
Genome Res., November 1, 2004; 14(11): 2273 - 2278.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
L. Gomez-Valero, A. Latorre, and F. J. Silva
The Evolutionary Fate of Nonfunctional DNA in the Bacterial Endosymbiont Buchnera aphidicola
Mol. Biol. Evol., November 1, 2004; 21(11): 2172 - 2181.
[Abstract] [Full Text] [PDF]

Home page
 J. Bacteriol.Home page
L. Gomez-Valero, M. Soriano-Navarro, V. Perez-Brocal, A. Heddi, A. Moya, J. M. Garcia-Verdugo, and A. Latorre
Coexistence of Wolbachia with Buchnera aphidicola and a Secondary Symbiont in the Aphid Cinara cedri
J. Bacteriol., October 1, 2004; 186(19): 6626 - 6633.
[Abstract] [Full Text] [PDF]

Home page
 Mol Biol EvolHome page
S. R. Bordenstein and J. J. Wernegreen
Bacteriophage Flux in Endosymbionts (Wolbachia): Infection Frequency, Lateral Transfer, and Recombination Rates
Mol. Biol. Evol., October 1, 2004; 21(10): 1981 - 1991.
[Abstract] [Full Text] [PDF]

Home page
 Microbiol. Mol. Biol. Rev.Home page
R. Gil, F. J. Silva, J. Pereto, and A. Moya
Determination of the Core of a Minimal Bacterial Gene Set
Microbiol. Mol. Biol. Rev., September 1, 2004; 68(3): 518 - 537.
[Abstract] [Full Text] [PDF]

Home page
 Nucleic Acids ResHome page
P. Mackiewicz, J. Zakrzewska-Czerwinska, A. Zawilak, M. R. Dudek, and S. Cebrat
Where does bacterial replication start? Rules for predicting the oriC region
Nucleic Acids Res., July 16, 2004; 32(13): 3781 - 3791.
[Abstract] [Full Text] [PDF]

Home page
 Appl. Environ. Microbiol.Home page
F. Wolschin, B. Holldobler, R. Gross, and E. Zientz
Replication of the Endosymbiotic Bacterium Blochmannia floridanus Is Correlated with the Developmental and Reproductive Stages of Its Ant Host
Appl. Envir. Microbiol., July 1, 2004; 70(7): 4096 - 4102.
[Abstract] [Full Text] [PDF]

Home page
 MicrobiologyHome page
E. P. C. Rocha
The replication-related organization of bacterial genomes
Microbiology, June 1, 2004; 150(6): 1609 - 1627.
[Abstract] [Full Text] [PDF]

Home page
 J. Bacteriol.Home page
B. Sabater-Munoz, R. C. H. J. van Ham, A. Moya, F. J. Silva, and A. Latorre
Evolution of the Leucine Gene Cluster in Buchnera aphidicola: Insights from Chromosomal Versions of the Cluster
J. Bacteriol., May 1, 2004; 186(9): 2646 - 2654.
[Abstract] [Full Text] [PDF]

Home page
 Genome Res.Home page
C. Rispe, F. Delmotte, R. C.H.J. van Ham, and A. Moya
Mutational and Selective Pressures on Codon and Amino Acid Usage in Buchnera, Endosymbiotic Bacteria of Aphids
Genome Res., January 1, 2004; 14(1): 44 - 53.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
N. A. Moran, G. R. Plague, J. P. Sandstrom, and J. L. Wilcox
A genomic perspective on nutrient provisioning by bacterial symbionts of insects
PNAS, November 25, 2003; 100(suppl_2): 14543 - 14548.
[Abstract] [Full Text]