MAREK'S DISEASE HERPES VIRUS: A CYTOMEGALOVIRUS?*

  1. Lucy F. Lee,
  2. Bernard Roizman,
  3. Patricia G. Spear†,
  4. Elliott D. Kieff‡,
  5. B. R. Burmester, and
  6. K. Nazerian
  1. DEPARTMENT OF MICROBIOLOGY, UNIVERSITY OF CHICAGO, CHICAGO, ILLINOIS
  2. U.S. DEPARTMENT OF AGRICULTURE, REGIONAL POULTRY RESEARCH LABORATORY (ARS), EAST LANSING, MICHIGAN

Abstract

The DNA of herpes viruses associated with Marek's disease of fowl contains 56-57 moles of guanine and cytosine per 100. The composition of its DNA and lack of infectiousness of cell-free preparations suggest that the herpes virus associated with Marek's disease belongs to the herpes virus group B which contains predominantly cytomegaloviruses.

Footnotes

  • ↵ † U.S. Public Health Service postdoctoral trainee (No. T01 HD-00297-01).

  • ↵ ‡ American Cancer Society postdoctoral fellow.

  • ↵ * This work was supported in part by grants from the American Cancer Society (E314-E) and the Leukemia Society.

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  1. PNAS 1969-11 vol. 64 no. 3 952-956
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