Absence of a Natural Inhibitor of the tRNA Methylases from Fetal and Tumor Tissues

  1. Sylvia J. Kerr
  1. Department of Microbiology, University of Colorado Medical Center, Denver, Col. 80220

Abstract

The inhibitor of tRNA methylases of normal adult tissues has been resolved into two fractions, a high molecular weight protein and a low molecular weight (<700) component. The high molecular weight component is absent from embryonic and tumor tissues, both of which are known to possess high tRNA methylase capacity.

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