A Unifying Hypothesis Concerning the Nature of Malignant Growth

  1. Robert W. Holley
  1. 1The Armand Hammer Center for Cancer Biology, The Salk Institute for Biological Studies, Post Office Box 1809, San Diego, California 92112

Abstract

It is suggested that the crucial change in a malignant cell is an alteration in the cell surface membrane that results in increased internal concentrations of nutrients that regulate cell growth.

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