Infection of Escherichia coli by T2 and T4 Bacteriophages as Seen in the Electron Microscope: T4 Head Morphogenesis*

  1. Lee D. Simon
  1. 1The Institute for Cancer Research, Philadelphia, Pennsylvania 19111

Abstract

Bacteriophage T4 capsids seem to be assembled on E. coli protoplasmic membranes. This process seems to involve “lumps” of head protein, which convert to τ particles, which in turn give rise to empty heads. The empty heads leave the bacterial membrane and are then filled with DNA in the central region of the cell. T4 gene 16 and 17 products appear to be necessary for head filling.

Footnotes

  • * This is paper IV in the series, “The Infection of Escherichia coli by T2 and T4 Bacteriophages as Seen in the Electron Microscope.”

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