Amphetamines: Correlation of Activity with Stability of Molecular Complexes

  1. Ming-Ta Sung and
  2. John A. Parker*
  1. Ames Research Center, NASA, Moffett Field, California 94035

Abstract

Molecular complexes have been prepared from several biologically active methoxyamphetamines and 1,4-dinitrobenzene. The association constants of these complexes, determined by nuclear magnetic resonance measurements, correlate linearly with the threshold hallucinogenic dose in humans.

Footnotes

  • ↵ * Address reprint requests to Dr. John A. Parker, Ames Research Center, NASA, Moffett Field, Calif. 94035.

« Previous | Next Article »Table of Contents

This Article

  1. PNAS 1972-06 vol. 69 no. 6 1346-1347
  1. » Abstract
  2. Full Text (PDF)
About Our New Site Design >>
Link: Advanced Search

This Week's Issue

  1. July 22, 2008, 105 (29)
  1. Current Issue
  1. Alert me to new issues of PNAS

Most