Molecular structure of a double helix that has non-Watson—Crick type base pairing formed by 2-substituted poly(A) and poly(U)

  1. Toshio Hakoshima,
  2. Toshikazu Fukui,
  3. Morio Ikehara, and
  4. Ken-ichi Tomita
  1. Faculty of Pharmaceutical Sciences, Osaka University, Suita, Osaka 565, Japan

Abstract

X-ray fiber diffraction studies of duplexes formed by 2-substituted poly(A) and poly(U) provide evidence for the existence of a double helical structure of poly(A)·poly(U) held together by Hoogsteen-type base pairing with parallel chain polarity.

« Previous | Next Article »Table of Contents

This Article

  1. PNAS 1981-12 vol. 78 no. 12 7309-7313
  1. » Abstract
  2. Full Text (PDF)
About Our New Site Design >>
Link: Advanced Search

This Week's Issue

  1. July 22, 2008, 105 (29)
  1. Current Issue
  1. Alert me to new issues of PNAS

Most