The retroviral oncogene qin belongs to the transcription factor family that includes the homeotic gene fork head

  1. J Li and
  2. P K Vogt
  1. Department of Microbiology, University of Southern California School of Medicine, Los Angeles 90033-1034.

Abstract

Avian sarcoma virus 31 contains an oncogene that we have named qin. qin codes for a nuclear protein, Qin, that is a member of the HNF-3/fork head family of transcriptional regulators. Within this family Qin is particularly closely related to rat brain factor 1 (BF-1), a telencephalon-specific gene presumed to play an important role in the development of the mammalian brain.

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  1. PNAS May 15, 1993 vol. 90 no. 10 4490-4494
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