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Evolutionary fate of retroposed gene copies in the human genome
- *Center for Integrative Genomics, University of Lausanne, Génopode, 1015 Lausanne, Switzerland; and
- †Computational and Molecular Population Genetics Laboratory, Zoological Institute, University of Bern, 3012 Bern, Switzerland
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Communicated by Wen-Hsiung Li, University of Chicago, Chicago, IL, December 30, 2005 (received for review December 14, 2005)
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Fig. 1.Examples of retrocopy types. (A) Noncoding fusion. (B) Coding fusion. (C) Retrocopy with newly acquired exons/introns. Retrocopy-derived sequences are light gray. Large boxes represent coding sequences. Small boxes indicate UTR sequences. Dotted lines represent introns. Transcript orientation is from left (5′) to right (3′). Transcripts are not drawn to scale.
Footnotes
- ‡To whom correspondence should be addressed. E-mail: henrik.kaessmann{at}unil.ch
- © 2006 by The National Academy of Sciences of the USA
