Matsumoto et al. 10.1073/pnas.0306709101.
Fig. 6. Histological analysis of pancreatic islets of Noc2–/– mice. Pancreatic b -cells (Top) and a-cells (Middle) were stained by antiinsulin and antiglucagon antibodies, respectively. (Bottom) Electron microscopic (EM) analyses of pancreatic bcells are shown. There are no apparent abnormalities in architecture of pancreatic islets or number of band acells in Noc2–/– mice. Insulin secretory granules are normal in shape and number in Noc2–/– mice. (Scale bar, 20 mm in Top and Middle; 1 mm in Bottom.)