Regulation of the GABA cell phenotype in hippocampus of schizophrenics and bipolars

Benes et al. 10.1073/pnas.0703806104.

Supporting Information

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SI Figure 3
SI Table 3
SI Table 4

SI Figure 3A
SI Figure 3B

Fig. 3. Network association analysis for GAD₆₇ in BDs and SZs. The respective databases for each of the two groups vs. normal controls contained 35 genes associated with the extracellular space, plasma membrane, cytoplasm, and nucleus (see text for details). (A) Stratum oriens of sector CA2/3. (B) Stratum oriens of sector CA1. Red and blue are used to indicate up- and down-regulated genes, respectively. The expression pattern of the BDs is fundamentally different from that of the SZs. The diagram represents the output of Ingenuity Pathways Analysis Application Note 0704. Genes shown as vertical rectangles, horizontal ovals, and inverted triangles represent G protein-coupled protein receptors, transcription factors, and kinases, respectively. A line interconnecting two genes without and with arrowheads indicates there is either binding only or an actual influence on the second gene.