Catana et al. 10.1073/pnas.0711622105.
Fig. 5. MR-compatible PET scanner. (A) Photograph of the PET insert. (B) Close-up view showing PSAPDs and associated electronics that reside under the high-frequency copper laminate. (C) PET insert in place within the 7-T Bruker BioSpin preclinical MRI system. DAQ, data acquisition; PCB, printed circuit board.
Fig. 6. Subtracted MR images in the presence of the powered and unpowered PET insert, demonstrating a featureless noise background. A standard RARE sequence was used.
Fig. 7. DWI-EPI. Five different DWIs of a live mouse brain, acquired in the presence of the PET insert.
Table 1. Characteristics of MRI-compatible PET insert
|
Characteristic |
Value |
|
No. of modules |
16 |
|
Detector ring diameter |
60 mm |
|
No. of detector rings |
8 |
|
No. of crystals/ring |
128 |
|
Total no. of crystals |
1,024 |
|
Axial FOV |
12 mm |
|
Transaxial FOV |
35 mm |
|
Insert length |
55 cm |
|
Insert outer diameter |
11.8 cm |
Table 2. Energy resolution (%) for four scintillator crystals (A) in one of the detector modules acquired while running various MR sequences with the specified parameters (B) and with no sequence running. (Similar results were obtained for all crystals. RARE, rapid acquisition with relaxation enhancement; FLASH, fast low-angle shot.)
A
|
Sequence |
Crystal |
|||
|
#8 |
#28 |
#40 |
#60 |
|
|
None |
21.84 |
21.71 |
18.38 |
23.06 |
|
RARE |
20.92 |
21.76 |
19.66 |
22.88 |
|
FLASH |
21.43 |
22.28 |
18.47 |
20.55 |
|
SE |
21.72 |
21.95 |
20.55 |
20.61 |
B
|
Parameter |
Sequence |
||
|
RARE |
SE |
FLASH |
|
|
Echo time, ms |
13.3 |
16 |
10 |
|
Repetition time, ms |
3,000 |
615 |
450 |
|
RARE factor |
8 |
- |
- |
|
Flip angle |
- |
- |
60° |
Similar results were obtained for all crystals. RARE, rapid acquisition with relaxation enhancement; FLASH, fast low-angle shot.