Learning and memory

  1. Hideyuki Okano*,,
  2. Tomoo Hirano, and
  3. Evan Balaban§
  1. *Division of Neuroanatomy (D12), Department of Neuroscience, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan; Department of Biophysics, Graduate School of Science, Kyoto University Sakyo-ku, Kyoto 606-8502, Japan; and §The Neurosciences Institute, 10640 John Jay Hopkins Drive, San Diego, CA 92121

Abstract

Memory is one of the most fundamental mental processes. Neuroscientists study this process by using extremely diverse strategies. Two different approaches aimed at understanding learning and memory were introduced in this symposium. The first focuses on the roles played by synaptic plasticity, especially in long-term depression in the cerebellum in motor learning, and its regulatory mechanism. The second approach uses an elegant chick-quail transplantation system on defined brain regions to study how neural populations interact in development to form behaviorally important neural circuits and to elucidate neurobiological correlates of perceptual and motor predispositions.

Footnotes

  • To whom reprint requests should be addressed. E-mail: okano{at}nana.med.osaka-u.ac.jp.

  • This paper is a summary of a session presented at the second annual Japanese–American Frontiers of Science symposium, held October 1–3, 1999, at the International Conference Center, Tsukuba, Japan.

  • Article published online before print: Proc. Natl. Acad. Sci. USA, 10.1073/pnas.210381897.

  • Article and publication date are at www.pnas.org/cgi/doi/10.1073/pnas.210381897

  • Abbreviations:
    LTD,
    long-term depression;
    VOR,
    vestibulo-ocular reflex
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