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This Article:

Michael P. Myers, Javor P. Stolarov, Charis Eng, Jing Li, Steven I. Wang, Michael H. Wigler, Ramon Parsons, and Nicholas K. Tonks
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
PNAS 1997 94: 9052-9057.

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A short N-terminal sequence of PTEN controls cytoplasmic localization and is required for suppression of cell growth
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Expression of the PTEN tumor suppressor gene in malignant mammary gland tumors of dogs
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PTEN: A crucial mediator of mitochondria-dependent apoptosis
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Increased PTEN expression due to transcriptional activation of PPARγ by Lovastatin and Rosiglitazone
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The relationship between microsatellite instability and PTEN gene mutations in endometrial cancer
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Effects of cotransfection of antisense-EGFR and wild-type PTEN cDNA on human glioblastoma cells
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Proteome profile changes that are differentially regulated by lipid and protein phosphatase activities of tumor suppressor PTEN in PTEN-expressing U-87 MG human glioblastoma cells
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Distinct Expression Profiles for PTEN Transcript and Its Splice Variants in Cowden Syndrome and Bannayan-Riley-Ruvalcaba Syndrome
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PI3K/Akt signaling regulates p27kip1 expression via Skp2 in PC3 and DU145 prostate cancer cells, but is not a major factor in p27kip1 regulation in LNCaP and PC346 cells
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Protein phosphatase activity of PTEN inhibited the invasion of glioma cells with epidermal growth factor receptor mutation type III expression
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Modulation of specific protein expression levels by PTEN: identification of AKAP121, DHFR, G3BP, Rap1, and RCC1 as potential targets of PTEN
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Akt signaling in thyroid neoplasia
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The complexity of PTEN: mutation, marker and potential target for therapeutic intervention
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17 beta-Estradiol prevents focal cerebral ischemic damages via activation of Akt and CREB in association with reduced PTEN phosphorylation in rats
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Pathological and molecular mechanisms of prostate carcinogenesis: Implications for diagnosis, detection, prevention, and treatment
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Inactivation of the PTEN gene protein product is associated with the invasiveness and metastasis, but not angiogenesis, of breast cancer
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Inhibition of phosphatidylinositol 3-kinase signaling negates the growth advantage imparted by a mutant epidermal growth factor receptor on human glioblastoma cells
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Mutational Analysis of the PTEN Gene in Endometrial Carcinoma and Hyperplasia
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SYNTHESIS AND FUNCTION OF 3-PHOSPHORYLATED INOSITOL LIPIDS
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PTEN AND MYOTUBULARIN: Novel Phosphoinositide Phosphatases
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THE DEVELOPMENTAL BIOLOGY OF BRAIN TUMORS
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Primary malignant lymphoma of the brain: analysis of MMAC1 (PTEN) tumor suppressor gene
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Protein tyrosine phosphatases in higher plants
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Mutation analysis of PTEN/MMAC1 in acute myeloid leukemia
Ta-Chih Liu, Pai-Mei Lin, Jan-Gowth Chang, Jing-Ping Lee, Tyen-Po Chen, and Sheng-Fung Lin
American Journal of Hematology (2000) 63: 170
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A novel PTEN mutation in a Japanese patient with Cowden disease
Y. Kubo, Y. Urano, Y. Hida, T. Ikeuchi, M. Nomoto, K. Kunitomo, and S. Arase
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Mutation Analysis of the PTEN/MMAC1 Gene in Japanese Patients with Cowden Disease
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Mutations of the human PTEN gene
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Multiple polyphosphoinositide pathways regulate apoptotic signalling in a dorsal root ganglion derived cell line
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Inactivation ofMMAC1 in bladder transitional-cell carcinoma cell lines and specimens
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Cowden Disease and Lhermitte-Duclos Disease: Characterization of a New Phakomatosis
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Severe Lhermitte-Duclos disease with unique germline mutation of PTEN
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American Journal of Medical Genetics (1999) 82: 290
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PTEN/MMAC1 Mutations in Hepatocellular Carcinomas: Somatic Inactivation of Both Alleles in Tumors
Naoki Kawamura, Hisaki Nagai, Koichi Bando, Masaaki Koyama, Satoshi Matsumoto, Takashi Tajiri, Masahiko Onda, Jiro Fujimoto, Takahiro Ueki, and Noboru Konishi
Cancer Science (1999) 90: 413
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Rare-type Mutations of MMAC1 Tumor Suppressor Gene in Human Glioma Cell Lines and Their Tumors of Origin
Shu-Jing Zhang, Sumio Endo, Tomio Ichikawa, Junichi Yoshimura, Kiyoshi Onda, Ryuichi Tanaka, Kazuo Washiyama, and Toshiro Kumanishi
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PTEN/MMAC1/TEP1 in signal transduction and tumorigenesis
Arnaud Besson, Stephen M. Robbins, and V. Wee Yong
European Journal of Biochemistry (1999) 263: 605
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Functional and molecular analyses of 10q deletions in human gliomas
Peter A. Steck, Huai Lin, Lauren A. Langford, Samar A. Jasser, Dimpy Koul, W.K. Alfred Yung, and Mark A. Pershouse
Genes Chromosomes and Cancer (1999) 24: 135
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Loss of heterozygosity at 10q in tumors of the upper respiratory tract is associated with poor prognosis
Daniela Gasparotto, Tamara Vukosavljevic, Sara Piccinin, Luigi Barzan, Sandro Sulfaro, Michela Armellin, Mauro Boiocchi, and Roberta Maestro
International Journal of Cancer (1999) 84: 432
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No evidence for germlinePTEN mutations in families with breast and brain tumours
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International Journal of Cancer (1999) 84: 216
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Somatic Mutations of the PTEN/MMAC1 Gene in Fifteen Japanese Endometrial Cancers: Evidence for Inactivation of Both Alleles
Keisuke Kurose, Koichi Bando, Koichi Fukino, Yuichi Sugisaki, Tsutomu Araki, and Mitsuru Emi
Cancer Science (1998) 89: 842
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Allelic imbalance, including deletion ofPTEN/MMAC1, at the Cowden disease locus on 10q22-23, in hamartomas from patients with cowden syndrome and germlinePTEN mutation
Debbie J. Marsh, Patricia L. M. Dahia, Valérie Coulon, Zimu Zheng, Françoise Dorion-Bonnet, Katherine M. Call, Randall Little, Albert Y. Lin, Rosalind A. Eeles, and Alisa M. Goldstein
Genes Chromosomes and Cancer (1998) 21: 61
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Inactivation of thePTEN/MMAC1/TEP1 gene in human lung cancers
Takashi Kohno, Mina Takahashi, Ryokuhei Manda, and Jun Yokota
Genes Chromosomes and Cancer (1998) 22: 152
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Mutations in the PTEN tumor suppressor gene in cervical carcinomas
Maxwell, Risinger, Shaw, Alvarez, Barrett, Futreal, and Berchuck
International Journal of Gynecological Cancer (1998) 8: 489
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Anti-phosphatases take the stage
Hunter Tony
Nature Genetics (1998) 18: 303
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Differential patterns of molecular genetic alterations define subsets among glioblastomas and oligoastrocytomas
Andreas Deimling
Neuropathology (1998) 18: 145
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Analysis of the PTEN gene in human meningiomas
Peters, Wellenreuther, Rollbrocker, Hayashi, Meyer-Puttlitz, Duerr, Lenartz, Marsh, Schramm, and Wiestler
Neuropathology and Applied Neurobiology (1998) 24: 3
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Genotypic Analysis of Tumor Suppressor Genes PTEN/MMAC1 and p53 in Head and Neck Squamous Cell Carcinomas
Ying C. Henderson, Eric Wang, and Gary L. Clayman
The Laryngoscope (1998) 108: 1553
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Mutational analysis of the TrkA gene in prostate cancer
Daniel J. George, Hiroyoshi Suzuki, G. Steven Bova, and John T. Isaacs
The Prostate (1998) 36: 172
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PTEN: Sometimes Taking It Off Can Be Better than Putting It On
M MYERS and N TONKS
The American Journal of Human Genetics (1997) 61: 1234
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