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This Article:

Tohru Ikuta, Sabrina Ausenda, and Maria D. Cappellini
Mechanism for fetal globin gene expression: Role of the soluble guanylate cyclase-cGMP-dependent protein kinase pathway
PNAS 2001 98: 1847-1852.

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IDENTIFICATION OF DIFFERENTIALLY EXPRESSED GENES INDUCED BY HYDROXYUREA IN RETICULOCYTES FROM SICKLE CELL ANAEMIA PATIENTS
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Anemia and splenomegaly in cGKI-deficient mice
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Neither DNA hypomethylation nor changes in the kinetics of erythroid differentiation explain 5-azacytidine's ability to induce human fetal hemoglobin
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Hydroxyurea nitrosylates and activates soluble guanylyl cyclase in human erythroid cells
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Expression of the ?-globin gene is sustained by the cAMP-dependent pathway in ?-thalassaemia
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Gene expression profiles of erythroid precursors characterise several mechanisms of the action of hydroxycarbamide in sickle cell anaemia
Flávia Chagas Costa, Anderson Ferreira da Cunha, André Fattori, Tarcísio de Sousa Peres, Gustavo Gilson Lacerda Costa, Tiago Ferraz Machado, Dulcinéia Martins de Albuquerque, Sheley Gambero, Carolina Lanaro, and Sara T. Olala Saad
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Fetal hemoglobin in sickle cell anemia: genetic determinants of response to hydroxyurea
Q Ma, D F Wyszynski, J J Farrell, A Kutlar, L A Farrer, C T Baldwin, and M H Steinberg
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Modifier genes and sickle cell anemia
Martin H Steinberg and Adeboye H Adewoye
Current Opinion in Hematology (2006) 13: 131???136
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Understanding mechanisms of γ-globin gene regulation to develop strategies for pharmacological fetal hemoglobin induction
Betty S. Pace and Sima Zein
Developmental Dynamics (2006) 235: 1727
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M. H. Steinberg
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Modulation of erythrocyte arginase activity in sickle cell disease patients during hydroxyurea therapy
Efemwonkiekie W. Iyamu, Renee Cecil, Leslie Parkin, Gerald Woods, Kwaku Ohene-Frempong, and Toshio Asakura
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Increased soluble guanylate cyclase activity in the red blood cells of sickle cell patients
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Pathophysiological-Based Approaches to Treatment of Sickle Cell Disease
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Hydroxyurea induces fetal hemoglobin by the nitric oxide–dependent activation of soluble guanylyl cyclase
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A role for nitric oxide in hydroxyurea-mediated fetal hemoglobin induction
S. Bruce King
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Nitric oxide donor properties of hydroxyurea in patients with sickle cell disease
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Nitric oxide and cyclic GMP levels in sickle cell patients receiving hydroxyurea
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Developing treatment for sickle cell disease
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