Table 2.
Lookup table for unstable triloops and stable tetraloops and hexaloops
| Hairpin | Ref(s). | ΔG°37 loop, kcal/mol |
|---|---|---|
| CAACG | 87 | 6.8 |
| GUUAC | 87 | 6.9 |
| CAACGG | 48 | 5.5 |
| CCAAGG | 48 | 3.3 |
| CCACGG | 48 | 3.7 |
| CCCAGG | 48 | 3.4 |
| CCGAGG | 48 | 3.5 |
| CCGCGG | 48 | 3.6 |
| CCUAGG | 48 | 3.7 |
| CCUCGG | 48 | 2.5 |
| CUAAGG | 48 | 3.6 |
| CUACGG | 47, 50 | 2.8 |
| CUCAGG | 48 | 3.7 |
| CUCCGG | 47 | 2.7 |
| CUGCGG | 47 | 2.8 |
| CUUAGG | 48 | 3.5 |
| CUUCGG | 47, 50 | 3.7 |
| ACAGUACU | 86 | 2.8 |
| ACAGUGCU | 86 | 2.9 |
| ACAGUGAU | 86 | 3.6 |
| ACAGUUCU | 86 | 1.8 |
-
For extra stable hairpins measured in 0.1 M Na+ (48, 87), placement was determined by assuming that the relative stability of loops remains constant between 0.1 and 1 M Na+. All values are based on experimental results rather than frequencies of occurrence as used in ref. 8. Unpaired nucleotides are shown in bold.
