Proceedings of the National Academy of Sciences: 115 (38)

New Research In

September 18, 2018; vol. 115 no. 38

This Week in PNAS

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In This Issue
PNAS September 18, 2018 115 (38) 9325-9326; https://doi.org/10.1073/iti3818115

News Feature

An in-depth look at trending science issues.

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News Feature: What’s the best way to build a molecular machine?
Front Matter
Stephen Ornes

PNAS September 18, 2018 115 (38) 9327-9330; https://doi.org/10.1073/pnas.1811689115

Profile

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Profile of Dana Carroll
Jennifer Viegas

PNAS September 18, 2018 115 (38) 9331-9333; published ahead of print September 10, 2018. https://doi.org/10.1073/pnas.1813829115

Commentaries

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Dark deactivation of chloroplast enzymes finally comes to light
Jean-Pierre Jacquot

PNAS September 18, 2018 115 (38) 9334-9335; published ahead of print August 30, 2018. https://doi.org/10.1073/pnas.1814182115
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Single-molecule study reveals the frenetic lives of proteins in gradients
Andrew W. Folkmann and Geraldine Seydoux

PNAS September 18, 2018 115 (38) 9336-9338; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1812248115
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Sprouty branches out to control T cell memory
Jana Raynor and Hongbo Chi

PNAS September 18, 2018 115 (38) 9339-9341; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1813460115
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Pathogens’ adaptation to the human host
Vanessa Sperandio

PNAS September 18, 2018 115 (38) 9342-9343; published ahead of print September 6, 2018. https://doi.org/10.1073/pnas.1813379115
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Defect engineering using crystal symmetry
Ramamoorthy Ramesh

PNAS September 18, 2018 115 (38) 9344-9346; published ahead of print August 31, 2018. https://doi.org/10.1073/pnas.1812554115

PNAS Plus Significance Statements

Brief statements written by the authors about the significance of their papers.

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PNAS Plus Significance Statements
PNAS September 18, 2018 115 (38) 9347-9350; https://doi.org/10.1073/pnas.ss11538

Artificial Molecular Machines Special Feature (Free Online)

Introduction
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  Growing community of artificial molecular machinists
  Damien Sluysmans and J. Fraser Stoddart
  
  PNAS September 18, 2018 115 (38) 9359-9361; https://doi.org/10.1073/pnas.1813973115
Perspectives
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  Molecular machines with bio-inspired mechanisms
  Liang Zhang, Vanesa Marcos, and David A. Leigh
  
  PNAS September 18, 2018 115 (38) 9397-9404; published ahead of print February 26, 2018. https://doi.org/10.1073/pnas.1712788115
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  Stochastically pumped adaptation and directional motion of molecular machines
  R. Dean Astumian
  
  PNAS September 18, 2018 115 (38) 9405-9413; published ahead of print March 9, 2018. https://doi.org/10.1073/pnas.1714498115
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  New molecular switch architectures
  Jared D. Harris, Mark J. Moran, and Ivan Aprahamian
  
  PNAS September 18, 2018 115 (38) 9414-9422; published ahead of print July 16, 2018. https://doi.org/10.1073/pnas.1714499115
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  Molecular rotary motors: Unidirectional motion around double bonds
  Diederik Roke, Sander J. Wezenberg, and Ben L. Feringa
  
  PNAS September 18, 2018 115 (38) 9423-9431; published ahead of print April 30, 2018. https://doi.org/10.1073/pnas.1712784115
Research Articles
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  Dynamic force spectroscopy of synthetic oligorotaxane foldamers
  From the Cover
  
  Damien Sluysmans, Floriane Devaux, Carson J. Bruns, J. Fraser Stoddart, and Anne-Sophie Duwez
  
  PNAS September 18, 2018 115 (38) 9362-9366; published ahead of print December 26, 2017. https://doi.org/10.1073/pnas.1712790115
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  Triangular cyclic rotaxanes: Size, fluctuations, and switching properties
  Prithvi Reddy, Edith M. Sevick, and David R. M. Williams
  
  PNAS September 18, 2018 115 (38) 9367-9372; published ahead of print January 29, 2018. https://doi.org/10.1073/pnas.1715790115
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  Structure of a monolayer of molecular rotors on aqueous subphase from grazing-incidence X-ray diffraction
  Jiří Kaleta, Jin Wen, Thomas F. Magnera, Paul I. Dron, Chenhui Zhu, and Josef Michl
  
  PNAS September 18, 2018 115 (38) 9373-9378; published ahead of print March 23, 2018. https://doi.org/10.1073/pnas.1712789115
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  Reversible photoswitching of encapsulated azobenzenes in water
  Dipak Samanta, Julius Gemen, Zonglin Chu, Yael Diskin-Posner, Linda J. W. Shimon, and Rafal Klajn
  
  PNAS September 18, 2018 115 (38) 9379-9384; published ahead of print May 1, 2018. https://doi.org/10.1073/pnas.1712787115
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  Remote electrochemical modulation of pK_a in a rotaxane by co-conformational allostery
  Giulio Ragazzon, Christian Schäfer, Paola Franchi, Serena Silvi, Benoit Colasson, Marco Lucarini, and Alberto Credi
  
  PNAS September 18, 2018 115 (38) 9385-9390; published ahead of print December 18, 2017. https://doi.org/10.1073/pnas.1712783115
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  Inchworm movement of two rings switching onto a thread by biased Brownian diffusion represent a three-body problem
  Christopher R. Benson, Christopher Maffeo, Elisabeth M. Fatila, Yun Liu, Edward G. Sheetz, Aleksei Aksimentiev, Abhishek Singharoy, and Amar H. Flood
  
  PNAS September 18, 2018 115 (38) 9391-9396; published ahead of print May 7, 2018. https://doi.org/10.1073/pnas.1719539115
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  Chemical control over membrane-initiated steroid signaling with a DNA nanocapsule
  Aneesh T. Veetil, Maulik S. Jani, and Yamuna Krishnan
  
  PNAS September 18, 2018 115 (38) 9432-9437; published ahead of print March 12, 2018. https://doi.org/10.1073/pnas.1712792115

Physical Sciences

Applied Physical Sciences
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  Morphological transitions of elastic filaments in shear flow
  Yanan Liu, Brato Chakrabarti, David Saintillan, Anke Lindner, and Olivia du Roure
  
  PNAS September 18, 2018 115 (38) 9438-9443; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1805399115
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  Origin of the emergent fragile-to-strong transition in supercooled water
  Rui Shi, John Russo, and Hajime Tanaka
  
  PNAS September 18, 2018 115 (38) 9444-9449; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1807821115
Biophysics and Computational Biology
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  FcαRI binding at the IgA1 C_H2–C_H3 interface induces long-range conformational changes that are transmitted to the hinge region
  Monica T. Posgai, Sam Tonddast-Navaei, Manori Jayasinghe, George M. Ibrahim, George Stan, and Andrew B. Herr
  
  PNAS September 18, 2018 115 (38) E8882-E8891; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1807478115
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  Franck–Condon picture of incoherent neutron scattering
  Gerald R. Kneller
  
  PNAS September 18, 2018 115 (38) 9450-9455; published ahead of print August 30, 2018. https://doi.org/10.1073/pnas.1718720115
- Open Access
  Mechanics of diseased red blood cells in human spleen and consequences for hereditary blood disorders
  He Li, Lu Lu, Xuejin Li, Pierre A. Buffet, Ming Dao, George E. Karniadakis, and Subra Suresh
  
  PNAS September 18, 2018 115 (38) 9574-9579; published ahead of print September 6, 2018. https://doi.org/10.1073/pnas.1806501115
Chemistry
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  Dynamic force spectroscopy of synthetic oligorotaxane foldamers
  From the Cover
  
  Damien Sluysmans, Floriane Devaux, Carson J. Bruns, J. Fraser Stoddart, and Anne-Sophie Duwez
  
  PNAS September 18, 2018 115 (38) 9362-9366; published ahead of print December 26, 2017. https://doi.org/10.1073/pnas.1712790115
- You have access
  Triangular cyclic rotaxanes: Size, fluctuations, and switching properties
  Prithvi Reddy, Edith M. Sevick, and David R. M. Williams
  
  PNAS September 18, 2018 115 (38) 9367-9372; published ahead of print January 29, 2018. https://doi.org/10.1073/pnas.1715790115
- You have access
  Structure of a monolayer of molecular rotors on aqueous subphase from grazing-incidence X-ray diffraction
  Jiří Kaleta, Jin Wen, Thomas F. Magnera, Paul I. Dron, Chenhui Zhu, and Josef Michl
  
  PNAS September 18, 2018 115 (38) 9373-9378; published ahead of print March 23, 2018. https://doi.org/10.1073/pnas.1712789115
- You have access
  Reversible photoswitching of encapsulated azobenzenes in water
  Dipak Samanta, Julius Gemen, Zonglin Chu, Yael Diskin-Posner, Linda J. W. Shimon, and Rafal Klajn
  
  PNAS September 18, 2018 115 (38) 9379-9384; published ahead of print May 1, 2018. https://doi.org/10.1073/pnas.1712787115
- You have access
  Remote electrochemical modulation of pK_a in a rotaxane by co-conformational allostery
  Giulio Ragazzon, Christian Schäfer, Paola Franchi, Serena Silvi, Benoit Colasson, Marco Lucarini, and Alberto Credi
  
  PNAS September 18, 2018 115 (38) 9385-9390; published ahead of print December 18, 2017. https://doi.org/10.1073/pnas.1712783115
- You have access
  Inchworm movement of two rings switching onto a thread by biased Brownian diffusion represent a three-body problem
  Christopher R. Benson, Christopher Maffeo, Elisabeth M. Fatila, Yun Liu, Edward G. Sheetz, Aleksei Aksimentiev, Abhishek Singharoy, and Amar H. Flood
  
  PNAS September 18, 2018 115 (38) 9391-9396; published ahead of print May 7, 2018. https://doi.org/10.1073/pnas.1719539115
- You have access
  Chemical control over membrane-initiated steroid signaling with a DNA nanocapsule
  Aneesh T. Veetil, Maulik S. Jani, and Yamuna Krishnan
  
  PNAS September 18, 2018 115 (38) 9432-9437; published ahead of print March 12, 2018. https://doi.org/10.1073/pnas.1712792115
- You have access
  Decreased water activity in nanoconfinement contributes to the folding of G-quadruplex and i-motif structures
  Sagun Jonchhe, Shankar Pandey, Tomoko Emura, Kumi Hidaka, Mohammad Akter Hossain, Prakash Shrestha, Hiroshi Sugiyama, Masayuki Endo, and Hanbin Mao
  
  PNAS September 18, 2018 115 (38) 9539-9544; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1805939115
Computer Sciences
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  Toward the first quantum simulation with quantum speedup
  Andrew M. Childs, Dmitri Maslov, Yunseong Nam, Neil J. Ross, and Yuan Su
  
  PNAS September 18, 2018 115 (38) 9456-9461; published ahead of print September 6, 2018. https://doi.org/10.1073/pnas.1801723115
Earth, Atmospheric, and Planetary Sciences
- Open Access
  Evolution of metazoan morphological disparity
  Bradley Deline, Jennifer M. Greenwood, James W. Clark, Mark N. Puttick, Kevin J. Peterson, and Philip C. J. Donoghue
  
  PNAS September 18, 2018 115 (38) E8909-E8918; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1810575115
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  Striking stationarity of large-scale climate model bias patterns under strong climate change
  Gerhard Krinner and Mark G. Flanner
  
  PNAS September 18, 2018 115 (38) 9462-9466; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1807912115
- Open Access
  Dynamic amplification of extreme precipitation sensitivity
  Ji Nie, Adam H. Sobel, Daniel A. Shaevitz, and Shuguang Wang
  
  PNAS September 18, 2018 115 (38) 9467-9472; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1800357115
Engineering
- Open Access
  Simultaneous polymerization and adhesion under hypoxia in sickle cell disease
  Dimitrios P. Papageorgiou, Sabia Z. Abidi, Hung-Yu Chang, Xuejin Li, Gregory J. Kato, George E. Karniadakis, Subra Suresh, and Ming Dao
  
  PNAS September 18, 2018 115 (38) 9473-9478; published ahead of print September 6, 2018. https://doi.org/10.1073/pnas.1807405115
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  Wetting controls of droplet formation in step emulsification
  Maximilian L. Eggersdorfer, Hansjörg Seybold, Alessandro Ofner, David A. Weitz, and André R. Studart
  
  PNAS September 18, 2018 115 (38) 9479-9484; published ahead of print September 5, 2018. https://doi.org/10.1073/pnas.1803644115
Physics
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  Designing antiphase boundaries by atomic control of heterointerfaces
  From the Cover
  
  Zhen Wang, Hangwen Guo, Shuai Shao, Mohammad Saghayezhian, Jun Li, Rosalba Fittipaldi, Antonio Vecchione, Prahald Siwakoti, Yimei Zhu, Jiandi Zhang, and E. W. Plummer
  
  PNAS September 18, 2018 115 (38) 9485-9490; published ahead of print August 13, 2018. https://doi.org/10.1073/pnas.1808812115
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  Floquet quantum criticality
  William Berdanier, Michael Kolodrubetz, S. A. Parameswaran, and Romain Vasseur
  
  PNAS September 18, 2018 115 (38) 9491-9496; published ahead of print August 29, 2018. https://doi.org/10.1073/pnas.1805796115
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  Universal quantum Hamiltonians
  Toby S. Cubitt, Ashley Montanaro, and Stephen Piddock
  
  PNAS September 18, 2018 115 (38) 9497-9502; published ahead of print August 30, 2018. https://doi.org/10.1073/pnas.1804949115
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  Nontrivial superconductivity in topological MoTe_2−xS_x crystals
  Yanan Li, Qiangqiang Gu, Chen Chen, Jun Zhang, Qin Liu, Xiyao Hu, Jun Liu, Yi Liu, Langsheng Ling, Mingliang Tian, Yong Wang, Nitin Samarth, Shiyan Li, Tong Zhang, Ji Feng, and Jian Wang
  
  PNAS September 18, 2018 115 (38) 9503-9508; published ahead of print August 30, 2018. https://doi.org/10.1073/pnas.1801650115
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  Structural fluctuations cause spin-split states in tetragonal (CH₃NH₃)PbI₃ as evidenced by the circular photogalvanic effect
  Daniel Niesner, Martin Hauck, Shreetu Shrestha, Ievgen Levchuk, Gebhard J. Matt, Andres Osvet, Miroslaw Batentschuk, Christoph Brabec, Heiko B. Weber, and Thomas Fauster
  
  PNAS September 18, 2018 115 (38) 9509-9514; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1805422115
- Open Access
  Metal–insulator-transition engineering by modulation tilt-control in perovskite nickelates for room temperature optical switching
  Zhaoliang Liao, Nicolas Gauquelin, Robert J. Green, Knut Müller-Caspary, Ivan Lobato, Lin Li, Sandra Van Aert, Johan Verbeeck, Mark Huijben, Mathieu N. Grisolia, Victor Rouco, Ralph El Hage, Javier E. Villegas, Alain Mercy, Manuel Bibes, Philippe Ghosez, George A. Sawatzky, Guus Rijnders, and Gertjan Koster
  
  PNAS September 18, 2018 115 (38) 9515-9520; published ahead of print September 5, 2018. https://doi.org/10.1073/pnas.1807457115
Sustainability Science
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  Infrastructure to enable deployment of carbon capture, utilization, and storage in the United States
  Ryan W. J. Edwards and Michael A. Celia
  
  PNAS September 18, 2018 115 (38) E8815-E8824; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1806504115

Environmental Sciences
- Open Access
  Global estimates of mortality associated with long-term exposure to outdoor fine particulate matter
  Richard Burnett, Hong Chen, Mieczysław Szyszkowicz, Neal Fann, Bryan Hubbell, C. Arden Pope III, Joshua S. Apte, Michael Brauer, Aaron Cohen, Scott Weichenthal, Jay Coggins, Qian Di, Bert Brunekreef, Joseph Frostad, Stephen S. Lim, Haidong Kan, Katherine D. Walker, George D. Thurston, Richard B. Hayes, Chris C. Lim, Michelle C. Turner, Michael Jerrett, Daniel Krewski, Susan M. Gapstur, W. Ryan Diver, Bart Ostro, Debbie Goldberg, Daniel L. Crouse, Randall V. Martin, Paul Peters, Lauren Pinault, Michael Tjepkema, Aaron van Donkelaar, Paul J. Villeneuve, Anthony B. Miller, Peng Yin, Maigeng Zhou, Lijun Wang, Nicole A. H. Janssen, Marten Marra, Richard W. Atkinson, Hilda Tsang, Thuan Quoc Thach, John B. Cannon, Ryan T. Allen, Jaime E. Hart, Francine Laden, Giulia Cesaroni, Francesco Forastiere, Gudrun Weinmayr, Andrea Jaensch, Gabriele Nagel, Hans Concin, and Joseph V. Spadaro
  
  PNAS September 18, 2018 115 (38) 9592-9597; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1803222115
Political Sciences
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  Perspective taking can promote short-term inclusionary behavior toward Syrian refugees
  Claire L. Adida, Adeline Lo, and Melina R. Platas
  
  PNAS September 18, 2018 115 (38) 9521-9526; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1804002115
Psychological and Cognitive Sciences
- Open Access
  Gain control explains the effect of distraction in human perceptual, cognitive, and economic decision making
  Vickie Li, Elizabeth Michael, Jan Balaguer, Santiago Herce Castañón, and Christopher Summerfield
  
  PNAS September 18, 2018 115 (38) E8825-E8834; published ahead of print August 30, 2018. https://doi.org/10.1073/pnas.1805224115
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  Infants distinguish between leaders and bullies
  Francesco Margoni, Renée Baillargeon, and Luca Surian
  
  PNAS September 18, 2018 115 (38) E8835-E8843; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1801677115
Social Sciences
- Open Access
  Americans’ occupational status reflects the status of both of their parents
  Michael Hout
  
  PNAS September 18, 2018 115 (38) 9527-9532; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1802508115
Sustainability Science
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  Linking economic growth pathways and environmental sustainability by understanding development as alternate social–ecological regimes
  Graeme S. Cumming and Stephan von Cramon-Taubadel
  
  PNAS September 18, 2018 115 (38) 9533-9538; published ahead of print September 5, 2018. https://doi.org/10.1073/pnas.1807026115

Biological Sciences

Applied Biological Sciences
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  Altered ER–mitochondria contact impacts mitochondria calcium homeostasis and contributes to neurodegeneration in vivo in disease models
  Kyu-Sun Lee, Sungun Huh, Seongsoo Lee, Zhihao Wu, Ae-Kyeong Kim, Ha-Young Kang, and Bingwei Lu
  
  PNAS September 18, 2018 115 (38) E8844-E8853; published ahead of print September 5, 2018. https://doi.org/10.1073/pnas.1721136115
Biochemistry
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  Structural elements required for coupling ion and substrate transport in the neurotransmitter transporter homolog LeuT
  Yuan-Wei Zhang, Sotiria Tavoulari, Steffen Sinning, Antoniya A. Aleksandrova, Lucy R. Forrest, and Gary Rudnick
  
  PNAS September 18, 2018 115 (38) E8854-E8862; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1716870115
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  Photoaffinity-engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples
  Bizhu Chu, An He, Yeteng Tian, Wan He, Peizhong Chen, Jintao Hu, Ruilian Xu, Wenbin Zhou, Mingjie Zhang, Pengyuan Yang, Shawn S. C. Li, Ying Sun, Pengfei Li, Tony Hunter, and Ruijun Tian
  
  PNAS September 18, 2018 115 (38) E8863-E8872; published ahead of print September 6, 2018. https://doi.org/10.1073/pnas.1805633115
- Open Access
  14-3-3εa directs the pulsatile transport of basal factors toward the apical domain for lumen growth in tubulogenesis
  Yuji Mizotani, Mayu Suzuki, Kohji Hotta, Hidenori Watanabe, Kogiku Shiba, Kazuo Inaba, Etsu Tashiro, Kotaro Oka, and Masaya Imoto
  
  PNAS September 18, 2018 115 (38) E8873-E8881; published ahead of print August 29, 2018. https://doi.org/10.1073/pnas.1808756115
- Open Access
  Nucleosomes inhibit target cleavage by CRISPR-Cas9 in vivo
  Inaugural Article
  
  Robert M. Yarrington, Surbhi Verma, Shaina Schwartz, Jonathan K. Trautman, and Dana Carroll
  
  PNAS September 18, 2018 115 (38) 9351-9358; published ahead of print September 10, 2018. https://doi.org/10.1073/pnas.1810062115
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  Decreased water activity in nanoconfinement contributes to the folding of G-quadruplex and i-motif structures
  Sagun Jonchhe, Shankar Pandey, Tomoko Emura, Kumi Hidaka, Mohammad Akter Hossain, Prakash Shrestha, Hiroshi Sugiyama, Masayuki Endo, and Hanbin Mao
  
  PNAS September 18, 2018 115 (38) 9539-9544; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1805939115
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  Ragulator and SLC38A9 activate the Rag GTPases through noncanonical GEF mechanisms
  Kuang Shen and David M. Sabatini
  
  PNAS September 18, 2018 115 (38) 9545-9550; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1811727115
- Open Access
  Ultrahigh-throughput functional profiling of microbiota communities
  Stanislav S. Terekhov, Ivan V. Smirnov, Maja V. Malakhova, Andrei E. Samoilov, Alexander I. Manolov, Anton S. Nazarov, Dmitry V. Danilov, Svetlana A. Dubiley, Ilya A. Osterman, Maria P. Rubtsova, Elena S. Kostryukova, Rustam H. Ziganshin, Maria A. Kornienko, Anna A. Vanyushkina, Olga N. Bukato, Elena N. Ilina, Valentin V. Vlasov, Konstantin V. Severinov, Alexander G. Gabibov, and Sidney Altman
  
  PNAS September 18, 2018 115 (38) 9551-9556; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1811250115
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  Mammalian STT3A/B oligosaccharyltransferases segregate N-glycosylation at the translocon from lipid-linked oligosaccharide hydrolysis
  Hua Lu, Charles S. Fermaintt, Natalia A. Cherepanova, Reid Gilmore, Nan Yan, and Mark A. Lehrman
  
  PNAS September 18, 2018 115 (38) 9557-9562; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1806034115
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  GEF mechanism revealed by the structure of SmgGDS-558 and farnesylated RhoA complex and its implication for a chaperone mechanism
  Hikaru Shimizu, Sachiko Toma-Fukai, Kenji Kontani, Toshiaki Katada, and Toshiyuki Shimizu
  
  PNAS September 18, 2018 115 (38) 9563-9568; published ahead of print September 6, 2018. https://doi.org/10.1073/pnas.1804740115
Biophysics and Computational Biology
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  FcαRI binding at the IgA1 C_H2–C_H3 interface induces long-range conformational changes that are transmitted to the hinge region
  Monica T. Posgai, Sam Tonddast-Navaei, Manori Jayasinghe, George M. Ibrahim, George Stan, and Andrew B. Herr
  
  PNAS September 18, 2018 115 (38) E8882-E8891; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1807478115
- You have access
  Structure of the membrane proximal external region of HIV-1 envelope glycoprotein
  Qingshan Fu, Md Munan Shaik, Yongfei Cai, Fadi Ghantous, Alessandro Piai, Hanqin Peng, Sophia Rits-Volloch, Zhijun Liu, Stephen C. Harrison, Michael S. Seaman, Bing Chen, and James J. Chou
  
  PNAS September 18, 2018 115 (38) E8892-E8899; published ahead of print September 5, 2018. https://doi.org/10.1073/pnas.1807259115
- You have access
  Franck–Condon picture of incoherent neutron scattering
  Gerald R. Kneller
  
  PNAS September 18, 2018 115 (38) 9450-9455; published ahead of print August 30, 2018. https://doi.org/10.1073/pnas.1718720115
- Open Access
  Simultaneous polymerization and adhesion under hypoxia in sickle cell disease
  Dimitrios P. Papageorgiou, Sabia Z. Abidi, Hung-Yu Chang, Xuejin Li, Gregory J. Kato, George E. Karniadakis, Subra Suresh, and Ming Dao
  
  PNAS September 18, 2018 115 (38) 9473-9478; published ahead of print September 6, 2018. https://doi.org/10.1073/pnas.1807405115
- Open Access
  Machining protein microcrystals for structure determination by electron diffraction
  Helen M. E. Duyvesteyn, Abhay Kotecha, Helen M. Ginn, Corey W. Hecksel, Emma V. Beale, Felix de Haas, Gwyndaf Evans, Peijun Zhang, Wah Chiu, and David I. Stuart
  
  PNAS September 18, 2018 115 (38) 9569-9573; published ahead of print August 31, 2018. https://doi.org/10.1073/pnas.1809978115
Cell Biology
- Open Access
  A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability
  Jessica B. A. Sadler, Dawn M. Wenzel, Lauren K. Williams, Marta Guindo-Martínez, Steven L. Alam, Josep M. Mercader, David Torrents, Katharine S. Ullman, Wesley I. Sundquist, and Juan Martin-Serrano
  
  PNAS September 18, 2018 115 (38) E8900-E8908; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1805504115
- You have access
  Chemical control over membrane-initiated steroid signaling with a DNA nanocapsule
  Aneesh T. Veetil, Maulik S. Jani, and Yamuna Krishnan
  
  PNAS September 18, 2018 115 (38) 9432-9437; published ahead of print March 12, 2018. https://doi.org/10.1073/pnas.1712792115
- Open Access
  Mechanics of diseased red blood cells in human spleen and consequences for hereditary blood disorders
  He Li, Lu Lu, Xuejin Li, Pierre A. Buffet, Ming Dao, George E. Karniadakis, and Subra Suresh
  
  PNAS September 18, 2018 115 (38) 9574-9579; published ahead of print September 6, 2018. https://doi.org/10.1073/pnas.1806501115
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  The chaperonin TRiC/CCT is essential for the action of bacterial glycosylating protein toxins like Clostridium difficile toxins A and B
  Marcus Steinemann, Andreas Schlosser, Thomas Jank, and Klaus Aktories
  
  PNAS September 18, 2018 115 (38) 9580-9585; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1807658115
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  Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast
  Carine Beaupere, Leticia Dinatto, Brian M. Wasko, Rosalyn B. Chen, Lauren VanValkenburg, Michael G. Kiflezghi, Mitchell B. Lee, Daniel E. L. Promislow, Weiwei Dang, Matt Kaeberlein, and Vyacheslav M. Labunskyy
  
  PNAS September 18, 2018 115 (38) 9586-9591; published ahead of print September 5, 2018. https://doi.org/10.1073/pnas.1804264115
Environmental Sciences
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  Global estimates of mortality associated with long-term exposure to outdoor fine particulate matter
  Richard Burnett, Hong Chen, Mieczysław Szyszkowicz, Neal Fann, Bryan Hubbell, C. Arden Pope III, Joshua S. Apte, Michael Brauer, Aaron Cohen, Scott Weichenthal, Jay Coggins, Qian Di, Bert Brunekreef, Joseph Frostad, Stephen S. Lim, Haidong Kan, Katherine D. Walker, George D. Thurston, Richard B. Hayes, Chris C. Lim, Michelle C. Turner, Michael Jerrett, Daniel Krewski, Susan M. Gapstur, W. Ryan Diver, Bart Ostro, Debbie Goldberg, Daniel L. Crouse, Randall V. Martin, Paul Peters, Lauren Pinault, Michael Tjepkema, Aaron van Donkelaar, Paul J. Villeneuve, Anthony B. Miller, Peng Yin, Maigeng Zhou, Lijun Wang, Nicole A. H. Janssen, Marten Marra, Richard W. Atkinson, Hilda Tsang, Thuan Quoc Thach, John B. Cannon, Ryan T. Allen, Jaime E. Hart, Francine Laden, Giulia Cesaroni, Francesco Forastiere, Gudrun Weinmayr, Andrea Jaensch, Gabriele Nagel, Hans Concin, and Joseph V. Spadaro
  
  PNAS September 18, 2018 115 (38) 9592-9597; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1803222115
Evolution
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  Evolution of metazoan morphological disparity
  Bradley Deline, Jennifer M. Greenwood, James W. Clark, Mark N. Puttick, Kevin J. Peterson, and Philip C. J. Donoghue
  
  PNAS September 18, 2018 115 (38) E8909-E8918; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1810575115
Genetics
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  Defective cortex glia plasma membrane structure underlies light-induced epilepsy in cpes mutants
  Govind Kunduri, Daniel Turner-Evans, Yutaka Konya, Yoshihiro Izumi, Kunio Nagashima, Stephen Lockett, Joost Holthuis, Takeshi Bamba, Usha Acharya, and Jairaj K. Acharya
  
  PNAS September 18, 2018 115 (38) E8919-E8928; published ahead of print September 5, 2018. https://doi.org/10.1073/pnas.1808463115
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  Cancer-driving H3G34V/R/D mutations block H3K36 methylation and H3K36me3–MutSα interaction
  Jun Fang, Yaping Huang, Guogen Mao, Shuang Yang, Gadi Rennert, Liya Gu, Haitao Li, and Guo-Min Li
  
  PNAS September 18, 2018 115 (38) 9598-9603; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1806355115
Immunology and Inflammation
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  Chemokine receptors CCR2 and CX3CR1 regulate viral encephalitis-induced hippocampal damage but not seizures
  Christopher Käufer, Chintan Chhatbar, Sonja Bröer, Inken Waltl, Luca Ghita, Ingo Gerhauser, Ulrich Kalinke, and Wolfgang Löscher
  
  PNAS September 18, 2018 115 (38) E8929-E8938; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1806754115
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  Lack of Sprouty 1 and 2 enhances survival of effector CD8⁺ T cells and yields more protective memory cells
  From the Cover
  
  Hesham M. Shehata, Shahzada Khan, Elise Chen, Patrick E. Fields, Richard A. Flavell, and Shomyseh Sanjabi
  
  PNAS September 18, 2018 115 (38) E8939-E8947; published ahead of print August 20, 2018. https://doi.org/10.1073/pnas.1808320115
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  High-resolution repertoire analysis reveals a major bystander activation of Tfh and Tfr cells
  Paul-Gydeon Ritvo, Ahmed Saadawi, Pierre Barennes, Valentin Quiniou, Wahiba Chaara, Karim El Soufi, Benjamin Bonnet, Adrien Six, Mikhail Shugay, Encarnita Mariotti-Ferrandiz, and David Klatzmann
  
  PNAS September 18, 2018 115 (38) 9604-9609; published ahead of print August 29, 2018. https://doi.org/10.1073/pnas.1808594115
Medical Sciences
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  Expansion of cancer stem cell pool initiates lung cancer recurrence before angiogenesis
  Lei Li, Jiang-Chao Li, Hong Yang, Xu Zhang, Lu-Lu Liu, Yan Li, Ting-Ting Zeng, Ying-Hui Zhu, Xiao-Dong Li, Yan Li, Dan Xie, Li Fu, and Xin-Yuan Guan
  
  PNAS September 18, 2018 115 (38) E8948-E8957; published ahead of print August 29, 2018. https://doi.org/10.1073/pnas.1806219115
- Open Access
  Phylogenetic approach to recover integration dates of latent HIV sequences within-host
  Bradley R. Jones, Natalie N. Kinloch, Joshua Horacsek, Bruce Ganase, Marianne Harris, P. Richard Harrigan, R. Brad Jones, Mark A. Brockman, Jeffrey B. Joy, Art F. Y. Poon, and Zabrina L. Brumme
  
  PNAS September 18, 2018 115 (38) E8958-E8967; published ahead of print September 5, 2018. https://doi.org/10.1073/pnas.1802028115
Microbiology
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  Enterotoxigenic E. coli virulence gene regulation in human infections
  From the Cover
  
  Alexander A. Crofts, Simone M. Giovanetti, Erica J. Rubin, Frédéric M. Poly, Ramiro L. Gutiérrez, Kawsar R. Talaat, Chad K. Porter, Mark S. Riddle, Barbara DeNearing, Jessica Brubaker, Milton Maciel Jr., Ashley N. Alcala, Subhra Chakraborty, Michael G. Prouty, Stephen J. Savarino, Bryan W. Davies, and M. Stephen Trent
  
  PNAS September 18, 2018 115 (38) E8968-E8976; published ahead of print August 20, 2018. https://doi.org/10.1073/pnas.1808982115
- Open Access
  Ehrlichia type IV secretion system effector Etf-2 binds to active RAB5 and delays endosome maturation
  Qi Yan, Mingqun Lin, Weiyan Huang, Omid Teymournejad, Jennifer M. Johnson, Franklin A. Hays, Zhimin Liang, Guangpu Li, and Yasuko Rikihisa
  
  PNAS September 18, 2018 115 (38) E8977-E8986; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1806904115
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  Distinct antiviral signatures revealed by the magnitude and round of influenza virus replication in vivo
  Louisa E. Sjaastad, Elizabeth J. Fay, Jessica K. Fiege, Marissa G. Macchietto, Ian A. Stone, Matthew W. Markman, Steven Shen, and Ryan A. Langlois
  
  PNAS September 18, 2018 115 (38) 9610-9615; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1807516115
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  Clinical and veterinary trypanocidal benzoxaboroles target CPSF3
  Richard J. Wall, Eva Rico, Iva Lukac, Fabio Zuccotto, Sara Elg, Ian H. Gilbert, Yvonne Freund, M. R. K. Alley, Mark C. Field, Susan Wyllie, and David Horn
  
  PNAS September 18, 2018 115 (38) 9616-9621; published ahead of print September 5, 2018. https://doi.org/10.1073/pnas.1807915115
Neuroscience
- Open Access
  Gain control explains the effect of distraction in human perceptual, cognitive, and economic decision making
  Vickie Li, Elizabeth Michael, Jan Balaguer, Santiago Herce Castañón, and Christopher Summerfield
  
  PNAS September 18, 2018 115 (38) E8825-E8834; published ahead of print August 30, 2018. https://doi.org/10.1073/pnas.1805224115
- Open Access
  Elimination of the error signal in the superior colliculus impairs saccade motor learning
  Yoshiko Kojima and Robijanto Soetedjo
  
  PNAS September 18, 2018 115 (38) E8987-E8995; published ahead of print September 5, 2018. https://doi.org/10.1073/pnas.1806215115
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  A pan-mammalian map of interhemispheric brain connections predates the evolution of the corpus callosum
  Rodrigo Suárez, Annalisa Paolino, Laura R. Fenlon, Laura R. Morcom, Peter Kozulin, Nyoman D. Kurniawan, and Linda J. Richards
  
  PNAS September 18, 2018 115 (38) 9622-9627; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1808262115
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  ASCT1 (Slc1a4) transporter is a physiologic regulator of brain d-serine and neurodevelopment
  Eitan Kaplan, Salman Zubedat, Inna Radzishevsky, Alec C. Valenta, Ohad Rechnitz, Hagit Sason, Clara Sajrawi, Oded Bodner, Kohtarou Konno, Kayoko Esaki, Dori Derdikman, Takeo Yoshikawa, Masahiko Watanabe, Robert T. Kennedy, Jean-Marie Billard, Avi Avital, and Herman Wolosker
  
  PNAS September 18, 2018 115 (38) 9628-9633; published ahead of print September 5, 2018. https://doi.org/10.1073/pnas.1722677115
Physiology
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  PKCε contributes to lipid-induced insulin resistance through cross talk with p70S6K and through previously unknown regulators of insulin signaling
  Brandon M. Gassaway, Max C. Petersen, Yulia V. Surovtseva, Karl W. Barber, Joshua B. Sheetz, Hans R. Aerni, Jane S. Merkel, Varman T. Samuel, Gerald I. Shulman, and Jesse Rinehart
  
  PNAS September 18, 2018 115 (38) E8996-E9005; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1804379115
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  Glutamate-activated BK channel complexes formed with NMDA receptors
  Jiyuan Zhang, Xin Guan, Qin Li, Andrea L. Meredith, Hui-Lin Pan, and Jiusheng Yan
  
  PNAS September 18, 2018 115 (38) E9006-E9014; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1802567115
Plant Biology
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  Plastid terminal oxidase requires translocation to the grana stacks to act as a sink for electron transport
  Piotr Stepien and Giles N. Johnson
  
  PNAS September 18, 2018 115 (38) 9634-9639; published ahead of print September 4, 2018. https://doi.org/10.1073/pnas.1719070115
Psychological and Cognitive Sciences
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  Mid-level visual features underlie the high-level categorical organization of the ventral stream
  Bria Long, Chen-Ping Yu, and Talia Konkle
  
  PNAS September 18, 2018 115 (38) E9015-E9024; published ahead of print August 31, 2018. https://doi.org/10.1073/pnas.1719616115
Sustainability Science
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  Linking economic growth pathways and environmental sustainability by understanding development as alternate social–ecological regimes
  Graeme S. Cumming and Stephan von Cramon-Taubadel
  
  PNAS September 18, 2018 115 (38) 9533-9538; published ahead of print September 5, 2018. https://doi.org/10.1073/pnas.1807026115

Correction (Online Only)

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Correction for Chen et al., Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13
PNAS September 18, 2018 115 (38) E9025; https://doi.org/10.1073/pnas.1814741115

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