MOLECULAR HYBRIDIZATION OF RADIOACTIVE DNA TO THE DNA OF CYTOLOGICAL PREPARATIONS

  1. Mary Lou Pardue and
  2. Joseph G. Gall
  1. KLINE BIOLOGY TOWER, YALE UNIVERSITY

Abstract

A method is presented for detecting the cellular location of specific DNA fractions. The technique involves the hybridization of a radioactive test DNA in solution to the stationary DNA of a cytological preparation. Sites of DNA binding are then detected by autoradiography. Experiments with DNA of the toad Xenopus are described.

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