Stimulation of DNA-Dependent RNA Synthesis by a Protein Associated with Ribosomes

  1. S. P. Mahadik and
  2. P. R. Srinivasan
  1. 1Department of Biochemistry, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, New York, N.Y. 10032

Abstract

A protein factor partially purified from ribosomes of Escherichia coli RCrel cells starved for an amino acid markedly stimulates DNA-dependent RNA synthesis by core and whole RNA polymerase. This protein factor appears to differ from the sigma factor and the M factor. The properties of this new factor and its mechanism of action have been explored.

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