Clock Mutants of Drosophila melanogaster

  1. Ronald J. Konopka and
  2. Seymour Benzer
  1. 1Division of Biology, California Institute of Technology, Pasadena, Calif. 91109

Abstract

Three mutants have been isolated in which the normal 24-hour rhythm is drastically changed. One mutant is arrhythmic; another has a period of 19 hr; a third has a period of 28 hr. Both the eclosion rhythm of a population and the locomotor activity of individual flies are affected. All these mutations appear to involve the same functional gene on the X chromosome.

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