Location of Ribosomal DNA in the Human Chromosome Complement

  1. A. S. Henderson,
  2. D. Warburton, and
  3. K. C. Atwood
  1. 1Department of Human Genetics and Development, College of Physicians and Surgeons, Columbia University, New York 10032

Abstract

Hybridization of 3H-labeled ribosomal RNA to human chromosomes on slides resulted in specific labeling of the satellite regions of chromosomes 13, 14, 15, 21, and 22, with an over-all efficiency of about 5%. Differences between D and G chromosomes, and between associated and unassociated satellites, were not significant. Labeling of all other parts of the preparations was nonspecific, and increased in the order: extrachromosomal regions < chromosome arms < centric regions.

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  1. PNAS November 1, 1972 vol. 69 no. 11 3394-3398
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