Interaction of Staphylococcus aureus toxin "superantigens" with human T cells

  1. Y W Choi,
  2. B Kotzin,
  3. L Herron,
  4. J Callahan,
  5. P Marrack, and
  6. J Kappler
  1. Howard Hughes Medical Institute, Division of Basic Immunology, Denver, CO.

Abstract

A modification of the polymerase chain reaction has been used to establish the fact that a collection of Staphylococcus aureus toxins are "superantigens," each of which interacts with the T-cell alpha beta receptor of human T cells by means of a specific set of V beta elements.

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  1. PNAS November 1, 1989 vol. 86 no. 22 8941-8945
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