A multisubunit complex containing the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 gene products isolated from yeast.

  1. B R Cairns,
  2. Y J Kim,
  3. M H Sayre,
  4. B C Laurent, and
  5. R D Kornberg
  1. Department of Cell Biology, Stanford University School of Medicine, CA 94305.

Abstract

A complex containing the products of the SWI1/ADR6, SWI2/SNF2, SWI3, SNF5, and SNF6 genes and four additional polypeptides has been purified from extracts of the yeast Saccharomyces cerevisiae. Physical association of these proteins was demonstrated by copurification and coimmunoprecipitation. A potent DNA-dependent ATPase copurified with the complex, and this activity was evidently associated with SWI2/SNF2.

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  1. PNAS March 1, 1994 vol. 91 no. 5 1950-1954
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