Karina Guziewicz and Artur Cideciyan explain a potential gene therapy approach for macular degeneration.
New Research In
Physical Sciences
Social Sciences
Featured Portals
Articles by Topic
Biological Sciences
Featured Portals
Articles by Topic
- Agricultural Sciences
- Anthropology
- Applied Biological Sciences
- Biochemistry
- Biophysics and Computational Biology
- Cell Biology
- Developmental Biology
- Ecology
- Environmental Sciences
- Evolution
- Genetics
- Immunology and Inflammation
- Medical Sciences
- Microbiology
- Neuroscience
- Pharmacology
- Physiology
- Plant Biology
- Population Biology
- Psychological and Cognitive Sciences
- Sustainability Science
- Systems Biology
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis
Haruo Ikeda, Tomoko Nonomiya, Masayo Usami, Toshio Ohta and Satoshi Ōmura
Haruo Ikeda
Tomoko Nonomiya
Masayo Usami
Toshio Ohta
-
Contributed by Satoshi Ōmura

Article Information
vol. 96 no. 17 9509-9514
PubMed:
Published By:
Print ISSN:
Online ISSN:
History:
- Accepted June 23, 1999
- Published August 17, 1999.
Copyright & Usage:
Copyright © 1999, The National Academy of Sciences
Author Information
Cited By...
This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.
- Christian HertweckAngewandte Chemie International Edition 2009 48 26
- Daniel Tillett, Elke Dittmann, Marcel Erhard, Hans von Döhren, Thomas Börner, Brett A NeilanChemistry & Biology 2000 7 10
- S. Omura, H. Ikeda, J. Ishikawa, A. Hanamoto, C. Takahashi, M. Shinose, Y. Takahashi, H. Horikawa, H. Nakazawa, T. Osonoe, H. Kikuchi, T. Shiba, Y. Sakaki, M. HattoriProceedings of the National Academy of Sciences 2001 98 21
- Markus Nett, Haruo Ikeda, Bradley S. MooreNatural Product Reports 2009 26 11
- Christopher J. Thibodeaux, Charles E. Melançon, Hung-wen LiuAngewandte Chemie International Edition 2008 47 51
- I Molnár, T Schupp, M Ono, RE Zirkle, M Milnamow, B Nowak-Thompson, N Engel, C Toupet, A Stratmann, DD Cyr, J Gorlach, JM Mayo, A Hu, S Goff, J Schmid, JM LigonChemistry & Biology 2000 7 2
- Polyketide synthases and nonribosomal peptide synthetases: the emerging view from bacterial genomicsStefano Donadio, Paolo Monciardini, Margherita SosioNatural Product Reports 2007 24 5
- A. Ayuso-Sacido, O. GenilloudMicrobial Ecology 2005 49 1
- Christian HertweckAngewandte Chemie 2009 121 26
- Richard W. Gantt, Pauline Peltier-Pain, Jon S. ThorsonNatural Product Reports 2011 28 11
- Trygve Brautaset, Olga N Sekurova, Håvard Sletta, Trond E Ellingsen, Arne R Strøm, Svein Valla, Sergey B ZotchevChemistry & Biology 2000 7 6
- Gitanjali Yadav, Rajesh S Gokhale, Debasisa MohantyJournal of Molecular Biology 2003 328 2
- Jing He, Christian HertweckChemistry & Biology 2003 10 12
- Clive Waldron, Patti Matsushima, Paul R Rosteck, Mary C Broughton, Jan Turner, Krishnamurthy Madduri, Kathryn P Crawford, Donald J Merlo, Richard H BaltzChemistry & Biology 2001 8 5
- Elizabeth S. Sattely, Michael A. Fischbach, Christopher T. WalshNatural Product Reports 2008 25 4
- Carmen Méndez, José A SalasTrends in Biotechnology 2001 19 11
- Isolation and characterization of the epothilone biosynthetic gene cluster from Sorangium cellulosumBryan Julien, Sanjay Shah, Rainer Ziermann, Robert Goldman, Leonard Katz, Chaitan KhoslaGene 2000 249 1-2
- Deborah Ann Miller, Lusong Luo, Nathan Hillson, Thomas A Keating, Christopher T WalshChemistry & Biology 2002 9 3
- Jesús F Aparicio, Roberto Fouces, Marta V Mendes, Noemı́ Olivera, Juan F Martı́nChemistry & Biology 2000 7 11
- Liangcheng Du, César Sánchez, Ben ShenMetabolic Engineering 2001 3 1
- Markiyan Oliynyk, Christian B. W. Stark, Apoorva Bhatt, Michelle A. Jones, Zoë A. Hughes-Thomas, Christopher Wilkinson, Zoryana Oliynyk, Yuliya Demydchuk, James Staunton, Peter F. LeadlayMolecular Microbiology 2003 49 5
- Yuhui Sun, Xiufen Zhou, Hui Dong, Guoquan Tu, Min Wang, Bofei Wang, Zixin DengChemistry & Biology 2003 10 5
- C. P. Ridley, H. Y. Lee, C. KhoslaProceedings of the National Academy of Sciences 2008 105 12
- Barbara Silakowski, Gabriele Nordsiek, Brigitte Kunze, Helmut Blöcker, Rolf MüllerChemistry & Biology 2001 8 1
- Haruo Ikeda, Kazuo Shin-ya, Satoshi OmuraJournal of Industrial Microbiology & Biotechnology 2014 41 2
- Jun Liu, Zixin Deng, Guiming Zhang, Tobias Kieser, Xiufen Zhou, Yuhui Sun, Kai Bao, Guoquan TuMicrobiology 2002 148 2
- Leticia Rodrı́guez, Ignacio Aguirrezabalaga, Nerea Allende, Alfredo F Braña, Carmen Méndez, José A SalasChemistry & Biology 2002 9 6
- René De Mot, Annabel H.A ParretTrends in Microbiology 2002 10 11
- Shunji Takahashi, Atsushi Toyoda, Yasuyo Sekiyama, Hiroshi Takagi, Toshihiko Nogawa, Masakazu Uramoto, Ryuichiro Suzuki, Hiroyuki Koshino, Takuto Kumano, Suresh Panthee, Tohru Dairi, Jun Ishikawa, Haruo Ikeda, Yoshiyuki Sakaki, Hiroyuki OsadaNature Chemical Biology 2011 7 7
- Shwan Rachid, Daniel Krug, Brigitte Kunze, Irene Kochems, Maren Scharfe, T. Mark Zabriskie, Helmut Blöcker, Rolf MüllerChemistry & Biology 2006 13 6
- L.-Y. Wang, Z.-L. Huang, G. Li, H.-X. Zhao, X.-H. Xing, W.-T. Sun, H.-P. Li, Z.-X. Gou, C.-Y. BaoJournal of Applied Microbiology 2010 108 3
- S. L. Kelly, D. E. KellyPhilosophical Transactions of the Royal Society B: Biological Sciences 2013 368 1612
- R. D. Kersten, N. Ziemert, D. J. Gonzalez, B. M. Duggan, V. Nizet, P. C. Dorrestein, B. S. MooreProceedings of the National Academy of Sciences 2013 110 47
- Shigeru Kitani, Haruo Ikeda, Takako Sakamoto, Satoru Noguchi, Takuya NihiraApplied Microbiology and Biotechnology 2009 82 6
- David C. Lamb, Haruo Ikeda, David R. Nelson, Jun Ishikawa, Tove Skaug, Colin Jackson, Satoshi Omura, Michael R. Waterman, Steven L. KellyBiochemical and Biophysical Research Communications 2003 307 3
- Shuhao Wang, Yuquan Xu, Erin A. Maine, E.M. Kithsiri Wijeratne, Patricia Espinosa-Artiles, A.A. Leslie Gunatilaka, István MolnárChemistry & Biology 2008 15 12
- Haruka Yamazaki, Ayami Tomono, Yasuo Ohnishi, Sueharu HorinouchiMolecular Microbiology 2004 53 2
- D Hoffmeister, K Ichinose, S Domann, B Faust, A Trefzer, G Dräger, A Kirschning, C Fischer, E Künzel, DW Bearden, J Rohr, A BechtholdChemistry & Biology 2000 7 11
- Christopher D. ReevesCritical Reviews in Biotechnology 2003 23 2
- Aurélien Ginolhac, Cyrille Jarrin, Patrick Robe, Guy Perrière, Timothy M. Vogel, Pascal Simonet, Renaud NalinJournal of Molecular Evolution 2005 60 6
- Kim Stutzman-Engwall, Steve Conlon, Ronald Fedechko, Hamish McArthur, Katja Pekrun, Yan Chen, Stephane Jenne, Charlene La, Na Trinh, Seran Kim, Ying-Xin Zhang, Richard Fox, Claes Gustafsson, Anke KrebberMetabolic Engineering 2005 7 1
- Felipe Lombó, Miranda Gibson, Lisa Greenwell, Alfredo F. Braña, Jürgen Rohr, José A. Salas, Carmen MéndezChemistry & Biology 2004 11 12
- Larissa M. Podust, Youngchang Kim, Miharu Arase, Benjamin A. Neely, Brian J. Beck, Horacio Bach, David H. Sherman, David C. Lamb, Steven L. Kelly, Michael R. WatermanJournal of Biological Chemistry 2003 278 14
- Tohru DairiThe Journal of Antibiotics 2005 58 4
- Jing He, Christian HertweckChemBioChem 2005 6 5
- Niranjan Parajuli, Devi B. Basnet, Hei Chan Lee, Jae Kyung Sohng, Kwangkyoung LiouArchives of Biochemistry and Biophysics 2004 425 2
- Christopher J. Thibodeaux, Charles E. Melançon, Hung-wen LiuAngewandte Chemie 2008 120 51
- Ute Galm, Ben ShenExpert Opinion on Drug Discovery 2006 1 5
- Jia Guo, Jinlei Zhao, Lili Li, Zhi Chen, Ying Wen, Jilun LiMolecular Genetics and Genomics 2010 283 2
- Laurenz Kellenberger, Ian S. Galloway, Guido Sauter, Günter Böhm, Ulf Hanefeld, Jesús Cortés, James Staunton, Peter F. LeadlayChemBioChem 2008 9 16
- János Varga, Krisztina Rigó, Sándor Kocsubé, Balázs Farkas, Károly PálResearch in Microbiology 2003 154 8
- Christopher J Wilkinson, Elizabeth J Frost, James Staunton, Peter F LeadlayChemistry & Biology 2001 8 12
- John H. Patterson, Malcolm J. McConville, Ruth E. Haites, Ross L. Coppel, Helen Billman-JacobeJournal of Biological Chemistry 2000 275 32
- Sven-Eric Wohlert, Natalia Lomovskaya, Kerry Kulowski, Leonid Fonstein, James L Occi, Keith M Gewain, Douglas J MacNeil, C.Richard HutchinsonChemistry & Biology 2001 8 7
- Satoshi ŌmuraTetrahedron 2011 67 35
- Lili Li, Jia Guo, Ying Wen, Zhi Chen, Yuan Song, Jilun LiJournal of Industrial Microbiology & Biotechnology 2010 37 7
- Zhi Chen, Jia Wen, Yuan Song, Ying Wen, JiLun LiChinese Science Bulletin 2007 52 5
- Peng Sun, Qunfei Zhao, Futao Yu, Hua Zhang, Zhuhua Wu, Yinyan Wang, Yan Wang, Qinglin Zhang, Wen LiuJournal of the American Chemical Society 2013 135 4
- Manuela Tosin, Lorena Betancor, Elaine Stephens, W. M. Ariel Li, Jonathan B. Spencer, Peter F. LeadlayChemBioChem 2010 11 4
- Jianuan Zhou, Haibao Zhang, Jien Wu, Qiongguang Liu, Pinggen Xi, Jasmine Lee, Jinling Liao, Zide Jiang, Lian-Hui ZhangMolecular Plant-Microbe Interactions 2011 24 10
- David C Lamb, F Peter Guengerich, Steven L Kelly, Michael R WatermanExpert Opinion on Drug Metabolism & Toxicology 2006 2 1
- Wenli Li, Jianhua Ju, Scott R. Rajski, Hiroyuki Osada, Ben ShenJournal of Biological Chemistry 2008 283 42
- Fumitaka Kudo, Atsushi Motegi, Kazutoshi Mizoue, Tadashi EguchiChemBioChem 2010 11 11
- Michelle Sauer, Ping Lu, Rajinder Sangari, Sarah Kennedy, Jon Polishook, Gerald Bills, Zhiqiang AnMycological Research 2002 106 4
- Malcolm J. McConville, Dharshini Jeevarajah, Helen Billman-Jacobe, John H. PattersonMicrobiology 2002 148 10
- Benjamin Busch, Nico Ueberschaar, Swantje Behnken, Yuki Sugimoto, Martina Werneburg, Nelly Traitcheva, Jing He, Christian HertweckAngewandte Chemie International Edition 2013 52 20
- J.D. van Elsas, A.J. Speksnijder, L.S. van OverbeekJournal of Microbiological Methods 2008 75 3
- Lei Chen, Yinhua Lu, Jun Chen, Weiwen Zhang, Dan Shu, Zhongjun Qin, Sheng Yang, Weihong JiangApplied Microbiology and Biotechnology 2008 80 2
- SangJoon Mo, Beom Seok Kim, Kevin A. ReynoldsChemistry & Biology 2005 12 2
- Kentaro Takada, Akihiro Ninomiya, Masato Naruse, Yi Sun, Masayuki Miyazaki, Yuichi Nogi, Shigeru Okada, Shigeki MatsunagaThe Journal of Organic Chemistry 2013 78 13
- K. T. Miyamoto, S. Kitani, M. Komatsu, H. Ikeda, T. NihiraMicrobiology 2011 157 8
- L. Lei, M. R. Waterman, A. J. Fulco, S. L. Kelly, D. C. LambProceedings of the National Academy of Sciences 2004 101 2
- Kim Stutzman-Engwall, Steve Conlon, Ronald Fedechko, Frank Kaczmarek, Hamish McArthur, Anke Krebber, Yan Chen, Jeremy Minshull, Sun Ai Raillard, Claes GustafssonBiotechnology and Bioengineering 2003 82 3
- Takushi Kaneko, Hamish McArthur, Joyce SutcliffeExpert Opinion on Therapeutic Patents 2000 10 4
- Andreas H. Ehrensberger, David K. WilsonJournal of Molecular Biology 2004 337 3
- Xiaolin Zhang, Zhi Chen, Meng Li, Ying Wen, Yuan Song, Jilun LiApplied Microbiology and Biotechnology 2006 72 5
- Jian-Bo Wang, Hai-Xue Pan, Gong-Li TangBioorganic & Medicinal Chemistry Letters 2011 21 11
- Ying Zhuo, Tao Zhang, Qi Wang, Pablo Cruz-Morales, Buchang Zhang, Mei Liu, Francisco Barona-Gómez, Lixin ZhangBiotechnology Journal 2014 9 3
- JinLei Zhao, Ying Wen, Zhi Chen, Yuan Song, JiLun LiChinese Science Bulletin 2007 52 5
- Chlud Kaddor, Karolin Biermann, Rainer Kalscheuer, Alexander SteinbüchelApplied Microbiology and Biotechnology 2009 84 1
- Jun Xu, Taifo Mahmud, Heinz G FlossArchives of Biochemistry and Biophysics 2003 411 2
- Jia Guo, Xuan Zhang, Shuai Luo, Fei He, Zhi Chen, Ying Wen, Jilun Li, Eric CascalesPLoS ONE 2013 8 8
- Satoshi ŌmuraAngewandte Chemie International Edition 2016 55 35
- Xiang-Jing Wang, Ji Zhang, Chong-Xi Liu, Dian-Liang Gong, Hui Zhang, Ji-Dong Wang, Yi-Jun Yan, Wen-Sheng XiangBioorganic & Medicinal Chemistry Letters 2011 21 18
- Fei He, Wenshuai Liu, Di Sun, Shuai Luo, Zhi Chen, Ying Wen, Jilun LiApplied Microbiology and Biotechnology 2014 98 1
- Zeynep Köksal, Ramazan Kalın, İlhami Gülçin, Hasan Özdemir, Ali AtaseverInternational Journal of Food Properties 2016 19 6
- Yongchang Ouyang, Shikun Dai, Lianwu Xie, M. S. Ravi Kumar, Wei Sun, Huimin Sun, Danling Tang, Xiang LiMarine Biotechnology 2010 12 3
- Hongseok Tae, Jae Kyung Sohng, Kiejung ParkBioprocess and Biosystems Engineering 2009 32 6
- Sarah C. Lievens, Tadeusz F. MolinskiOrganic Letters 2005 7 11
- Shigehiro Tohyama, Katsumi Kakinuma, Tadashi EguchiThe Journal of Antibiotics 2006 59 1
- Analysis of the enzymatic domains in the modular portion of the coronafacic acid polyketide synthaseSao Jiralerspong, Vidhya Rangaswamy, Carol L. Bender, Ronald J. ParryGene 2001 270 1-2
- Bo Pang, Min Wang, Wen LiuNatural Product Reports 2016 33 2
- Meng Li, Zhi Chen, Xiuping Lin, Xuan Zhang, Yuan Song, Ying Wen, Jilun LiBioorganic & Medicinal Chemistry Letters 2008 18 20
- Yongjun Zhou, Jialiang Li, Jing Zhu, Shi Chen, Linquan Bai, Xiufen Zhou, Houming Wu, Zixin DengChemistry & Biology 2008 15 6
- Peng Yin, Yong-Hong Wang, Si-Liang Zhang, Ju Chu, Ying-Ping Zhuang, Mei-Long Wang, Jin ZhouJournal of Microbiological Methods 2008 73 2
- Na Ke, Jerome Baudry, Thomas M. Makris, Mary A. Schuler, Stephen G. SligarArchives of Biochemistry and Biophysics 2005 436 1
- Haruo Ikeda, Kazuo Shin-ya, Tohru Nagamitsu, Hiroshi TomodaJournal of Industrial Microbiology & Biotechnology 2016 43 2-3
- Jian-Bo Wang, Feng Zhang, Jin-Yue Pu, Juan Zhao, Qun-Fei Zhao, Gong-Li TangBiotechnology Letters 2014 36 4
- Lijiang Song, Luisa Laureti, Christophe Corre, Pierre Leblond, Bertrand Aigle, Gregory L ChallisThe Journal of Antibiotics 2014 67 1
- Songhee Han, Tan-Viet Pham, Joo-Hwan Kim, Young-Ran Lim, Hyoung-Goo Park, Gun-Su Cha, Chul-Ho Yun, Young-Jin Chun, Lin-Woo Kang, Donghak KimArchives of Biochemistry and Biophysics 2015 575
- Melinda L. Micallef, Paul M. D’Agostino, Deepti Sharma, Rajesh Viswanathan, Michelle C. MoffittBMC Genomics 2015 16 1
- Yogan Khatri, Frank Hannemann, Olena Perlova, Rolf Müller, Rita BernhardtFEBS Letters 2011 585 11
- Adrian T. Keatinge-ClayChemical Reviews 2017 117 8
- Jeffrey D. Rudolf, Liao-Bin Dong, Karina Manoogian, Ben ShenJournal of the American Chemical Society 2016 138 51
- Satoshi Yuzawa, Jay D Keasling, Leonard KatzThe Journal of Antibiotics 2016 69 7
- Benjamin Busch, Nico Ueberschaar, Swantje Behnken, Yuki Sugimoto, Martina Werneburg, Nelly Traitcheva, Jing He, Christian HertweckAngewandte Chemie 2013 125 20
- Namthip Sitachitta, Nicole B. Lopanik, Yingqing Mao, David H. ShermanJournal of Biological Chemistry 2007 282 29
- Peng Yin, You-Yuan Li, Jin Zhou, Yong-Hong Wang, Si-Liang Zhang, Bang-Ce Ye, Wei-Feng Ge, Yue-Lan XiaJournal of Proteomics 2013 79
- Jine Li, Zhoujie Xie, Min Wang, Guomin Ai, Yihua Chen, Marie-Joelle VirollePLOS ONE 2015 10 3
- Changsheng Wu, Marnix H. Medema, Rianne M. Läkamp, Le Zhang, Pieter C. Dorrestein, Young Hae Choi, Gilles P. van WezelACS Chemical Biology 2016 11 2
- Multiple regulatory genes in the salinomycin biosynthetic gene cluster ofStreptomyces albus CCM 4719R. Knirschová, R. Nováková, L. Fecková, J. Timko, J. Turňa, J. Bistáková, J. KormanecFolia Microbiologica 2007 52 4
- Peng Sun, Qunfei Zhao, Hua Zhang, Jiequn Wu, Wen LiuChemBioChem 2014 15 5
- Renjun Yang, Xingchao Liu, Ying Wen, Yuan Song, Zhi Chen, Jilun LiApplied Microbiology and Biotechnology 2015 99 24
- Guang-Rong Zhao, Ting Luo, Yong-Jin Zhou, Xin Jiang, Bin Qiao, Feng-Ming Yu, Ying-Jin YuanApplied Microbiology and Biotechnology 2009 83 2
- Barrie Wilkinson, Steven G Kendrew, Rose M Sheridan, Peter F LeadlayExpert Opinion on Therapeutic Patents 2003 13 10
- Ji Zhang, Jing An, Ji-Jia Wang, Yi-Jun Yan, Hai-Rong He, Xiang-Jing Wang, Wen-Sheng XiangApplied Microbiology and Biotechnology 2013 97 23
- T. Ashton Cropp, Beom S. Kim, Brian J. Beck, Yeo Joon Yoon, David H. Sherman, Kevin A. ReynoldsBiotechnology and Genetic Engineering Reviews 2002 19 1
- Shikun Dai, Yongchang Ouyang, Guanghua Wang, Xiang LiCurrent Microbiology 2011 63 1
- Molecules and Cells 2016 39 3
- Miloje Savic, Branka VasiljevicJournal of Industrial Microbiology & Biotechnology 2006 33 6
- Juan F Martín, Antonio Rodríguez-García, Paloma LirasThe Journal of Antibiotics 2017 70 5
- Suandi Pratama Sultan, Shigeru Kitani, Kiyoko T Miyamoto, Hiroyuki Iguchi, Tokitaka Atago, Haruo Ikeda, Takuya NihiraApplied Microbiology and Biotechnology 2016 100 22
- Satoshi Yuzawa, Clara H Eng, Leonard Katz, Jay D KeaslingThe Journal of Antibiotics 2014 67 2
- John A. GerltBiochemistry 2017 56 33
- Haruo IkedaBioscience, Biotechnology, and Biochemistry 2017 81 1
- Satoshi Yuzawa, Jay D Keasling, Leonard KatzThe Journal of Antibiotics 2017 70 4
- Xiang-Jing Wang, Bo Zhang, Yi-Jun Yan, Jing An, Ji Zhang, Chong-Xi Liu, Wen-Sheng Xiang, J.B. BellGenome 2013 56 11
- Yasushi Ogasawara, Kinya Katayama, Atsushi Minami, Miyuki Otsuka, Tadashi Eguchi, Katsumi KakinumaChemistry & Biology 2004 11 1
- Myoun-Su Kim, Wan-Je Cho, Myoung Chong Song, Seong-Whan Park, Kaeun Kim, Eunji Kim, Naryeong Lee, Sang-Jip Nam, Ki-Hoon Oh, Yeo Joon YoonMicrobial Cell Factories 2017 16 1
- Lixia Gou, Qiulin Wu, Shuangjun Lin, Xiangmei Li, Jingdan Liang, Xiufen Zhou, Derong An, Zixin Deng, Zhijun WangApplied Microbiology and Biotechnology 2013 97 18
- Leslie M. Hicks, Carl J. Balibar, Christopher T. Walsh, Neil L. Kelleher, Nathan J. HillsonBiophysical Journal 2006 91 7
- Ke Shang, Youjia Hu, Chunbao Zhu, Baoquan ZhuWorld Journal of Microbiology and Biotechnology 2008 24 7
- Jinsong Guo, Ruonan Ma, Bo Su, Yinglong Li, Jue Zhang, Jing FangScientific Reports 2016 6 1
- Meredith A. Skiba, Andrew P. Sikkema, Nathan A. Moss, Collin L. Tran, Rebecca M. Sturgis, Lena Gerwick, William H. Gerwick, David H. Sherman, Janet L. SmithACS Chemical Biology 2017 12 12
- Ayako Nara, Takuya Hashimoto, Mamoru Komatsu, Makoto Nishiyama, Tomohisa Kuzuyama, Haruo IkedaThe Journal of Antibiotics 2017 70 5
- Jesus F. Barajas, Jacquelyn M. Blake-Hedges, Constance B. Bailey, Samuel Curran, Jay. D. KeaslingSynthetic and Systems Biotechnology 2017 2 3
- Lei Li, LinQuan Bai, XiuFen Zhou, ZiXin DengScience Bulletin 2009 54 7
- Jun-Gyu Ban, Min-Woo Woo, Bo-Ram Lee, Mi-Jin Lee, Si-Sun Choi, Eung-Soo KimJournal of Industrial Microbiology & Biotechnology 2014 41 5
- Fanli Zeng, Jinping Zang, Suhua Zhang, Zhimin Hao, Jingao Dong, Yibin LinBMC Biotechnology 2017 17 1
- Hai Hou, Ruiying Li, Xiaoyan Wang, Zhen Yuan, Xuemeng Liu, Zhenmin Chen, Xiaoling XuActa Crystallographica Section F Structural Biology Communications 2015 71 7
- Satoshi ŌmuraAngewandte Chemie 2016 128 35
- Sang Kil Lee, Jay Sung Joong Hong, Cha Yong Choi, Jong Seog Ahn, Yeo Joon YoonEnzyme and Microbial Technology 2006 39 4
- Wei Gong, Weihong Jiang, Yunliu Yang, Juishen ChiaoFolia Microbiologica 2004 49 4
- Xuan Lei, Lingxin Kong, Chen Zhang, Qian Liu, Fen Yao, Weike Zhang, Zixin Deng, Delin YouMolecular BioSystems 2013 9 3
- Jinsong Chen, Mei Liu, Xueting Liu, Jin Miao, Chengzhang Fu, Heyong Gao, Rolf Müller, Qing Zhang, Lixin ZhangSynthetic and Systems Biotechnology 2016 1 1
- Zhiguo Wang, Shuo Zhou, Shuangling Zhang, Sa Zhang, Fangmeng Zhu, Xiaolu Jin, Zhenming Chen, Xiaoling XuScientific Reports 2017 7 1
- Satoshi Yuzawa, Tyler W. H. Backman, Jay D. Keasling, Leonard KatzJournal of Industrial Microbiology & Biotechnology 2018
- Nuria Menéndez, Mohammad Nur-e-Alam, Alfredo F. Braña, Jürgen Rohr, José A. Salas, Carmen MéndezChemistry & Biology 2004 11 1
- Xiaolin Zhang, Zhi Chen, Jinlei Zhao, Yuan Song, Ying Wen, Jilun LiChinese Science Bulletin 2004 49 4
- Haruo IKEDATRENDS IN THE SCIENCES 2016 21 2
- Ivy Grace Umadhay Pait, Shigeru Kitani, Farah Wahidah Roslan, Dana Ulanova, Masayoshi Arai, Haruo Ikeda, Takuya NihiraJournal of Industrial Microbiology & Biotechnology 2018 45 2
- Rich BodenFEMS Microbiology Letters 2015 362 23
- Nguyen Huy Thuan, Dipesh Dhakal, Anaya Raj Pokhrel, Luan Luong Chu, Thi Thuy Van Pham, Anil Shrestha, Jae Kyung SohngApplied Microbiology and Biotechnology 2018
- Qian Deng, Li Zhou, Meizhong Luo, Zixin Deng, Changming ZhaoSynthetic and Systems Biotechnology 2017 2 1
- Xiaoqing Song, Yun Zhang, Xudong Zhu, Yonghong Wang, Ju Chu, Yingping ZhuangBiotechnology and Bioprocess Engineering 2017 22 5
- Aleem B. Pinjari, Pallaval Veera Bramhachari2018
- Hiroki Ando, Robert Citorik, Sara Cleto, Sebastien Lemire, Mark Mimee, Timothy Lu2014
- Michael J. Smanski, Xu-Dong Qu, Wen Liu, Ben Shen, Yi Tang, Yi Yu, Zi-Xin Deng2012
- Anja Greule, Jeanette E. Stok, James J. De Voss, Max J. CryleNatural Product Reports 2018
Online Impact
Article usage
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis
Haruo Ikeda, Tomoko Nonomiya, Masayo Usami, Toshio Ohta, Satoshi Ōmura
Proceedings of the National Academy of Sciences Aug 1999, 96 (17) 9509-9514; DOI: 10.1073/pnas.96.17.9509
Citation Manager Formats
Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in Streptomyces avermitilis
Haruo Ikeda, Tomoko Nonomiya, Masayo Usami, Toshio Ohta, Satoshi Ōmura
Proceedings of the National Academy of Sciences Aug 1999, 96 (17) 9509-9514; DOI: 10.1073/pnas.96.17.9509
More Articles of This Classification
Biological Sciences
Related Content
- No related articles found.
Cited by...
- SdrA, a New DeoR Family Regulator Involved in Streptomyces avermitilis Morphological Development and Antibiotic Production
- Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules
- Characterization of SAV7471, a TetR-Family Transcriptional Regulator Involved in the Regulation of Coenzyme A Metabolism in Streptomyces avermitilis
- Post-PKS Tailoring Steps of the Spiramycin Macrolactone Ring in Streptomyces ambofaciens
- Microbial cytochromes P450: biodiversity and biotechnology. Where do cytochromes P450 come from, what do they do and what can they do for us?
- Characterization of the Biosynthesis Gene Cluster for the Pyrrole Polyether Antibiotic Calcimycin (A23187) in Streptomyces chartreusis NRRL 3882
- Genome Sequence of the Milbemycin-Producing Bacterium Streptomyces bingchenggensis
- Cloning of Separate Meilingmycin Biosynthesis Gene Clusters by Use of Acyltransferase-Ketoreductase Didomain PCR Amplification
- Characterization of the Tautomycin Biosynthetic Gene Cluster from Streptomyces spiroverticillatus Unveiling New Insights into Dialkylmaleic Anhydride and Polyketide Biosynthesis
- Evolution of polyketide synthases in bacteria
- Analysis of a Parallel Branch in the Mitomycin Biosynthetic Pathway Involving the mitN-Encoded Aziridine N-Methyltransferase
- Biosynthetic Gene Cluster for the Polyenoyltetramic Acid {alpha}-Lipomycin
- Analysis of the Loading and Hydroxylation Steps in Lankamycin Biosynthesis in Streptomyces rochei
- Characterization of the Nodularin Synthetase Gene Cluster and Proposed Theory of the Evolution of Cyanobacterial Hepatotoxins
- Cloning, Sequencing, and Functional Analysis of an Iterative Type I Polyketide Synthase Gene Cluster for Biosynthesis of the Antitumor Chlorinated Polyenone Neocarzilin in "Streptomyces carzinostaticus"
- Phylogenetic Analysis of Polyketide Synthase I Domains from Soil Metagenomic Libraries Allows Selection of Promising Clones
- In Vivo Analysis of the Regulatory Genes in the Nystatin Biosynthetic Gene Cluster of Streptomyces noursei ATCC 11455 Reveals Their Differential Control Over Antibiotic Biosynthesis
- Genes Coding for Hepatotoxic Heptapeptides (Microcystins) in the Cyanobacterium Anabaena Strain 90
- Availability of specific reductases controls the temporal activity of the cytochrome P450 complement of Streptomyces coelicolor A3(2)
- The 1.92-A Structure of Streptomyces coelicolor A3(2) CYP154C1: A NEW MONOOXYGENASE THAT FUNCTIONALIZES MACROLIDE RING SYSTEMS
- Cloning and Analysis of a DNA Fragment Stimulating Avermectin Production in Various Streptomyces avermitilis Strains
- Analysis of an 8.1-kb DNA Fragment Contiguous with the Erythromycin Gene Cluster of Saccharopolyspora erythraea in the eryCI-Flanking Region
- Genome sequence of an industrial microorganism Streptomyces avermitilis: Deducing the ability of producing secondary metabolites
- Functional Analysis of OleY L-Oleandrosyl 3-O-Methyltransferase of the Oleandomycin Biosynthetic Pathway in Streptomyces antibioticus
- Characterization and Analysis of the PikD Regulatory Factor in the Pikromycin Biosynthetic Pathway of Streptomyces venezuelae
- Engineered Fatty Acid Biosynthesis in Streptomyces by Altered Catalytic Function of {beta}-Ketoacyl-Acyl Carrier Protein Synthase III
- Identification of a Methyltransferase from Mycobacterium smegmatis Involved in Glycopeptidolipid Synthesis
- Genome sequence of an industrial microorganism Streptomyces avermitilis: Deducing the ability of producing secondary metabolites
- Identification of a Methyltransferase from Mycobacterium smegmatis Involved in Glycopeptidolipid Synthesis
Similar Articles
You May Also be Interested in
PNAS Profile of Alexander Rudensky, winner of the Vilcek Prize in Biomedical Science
Ambrosia beetles, which bore into host trees and cultivate fungi, select trees with elevated ethanol content because ethanol promotes growth of preferred fungal species.
Image courtesy of Gernot Kunz (Karl-Franzens-Universität Graz, Graz, Austria).
A study examines the walking and climbing capabilities of human ancestors.
Researchers have engineered the complete biosynthetic pathway for a potential cancer drug into a single yeast strain, paving the way toward the commercial brewing of medically important compounds.
Image courtesy of Pixabay/Republica.