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A randomized trial of the effect of estrogen and testosterone on economic behavior

Niklas Zethraeus, Ljiljana Kocoska-Maras, Tore Ellingsen, Bo von Schoultz, Angelica Lindén Hirschberg, and Magnus Johannesson
PNAS published ahead of print April 6, 2009 https://doi.org/10.1073/pnas.0812757106
Niklas Zethraeus
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Ljiljana Kocoska-Maras
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Tore Ellingsen
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Bo von Schoultz
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Angelica Lindén Hirschberg
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Magnus Johannesson
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  1. Edited by George A. Akerlof, University of California, Berkeley, CA, and approved February 17, 2009 (received for review December 15, 2008)

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Abstract

Existing correlative evidence suggests that sex hormones may affect economic behavior such as risk taking and reciprocal fairness. To test this hypothesis we conducted a double-blind randomized study. Two-hundred healthy postmenopausal women aged 50–65 years were randomly allocated to 4 weeks of treatment with estrogen, testosterone, or placebo. At the end of the treatment period, the subjects participated in a series of economic experiments that measure altruism, reciprocal fairness, trust, trustworthiness, and risk attitudes. There was no significant effect of estrogen or testosterone on any of the studied behaviors.

Keywords:
  • sex hormones
  • trust game
  • ultimatum game
  • risk aversion

Footnotes

  • 1To whom correspondence should be addressed. E-mail: magnus.johannesson{at}hhs.se
  • Author contributions: N.Z., L.K.-M., T.E., B.v.S., A.L.H., and M.J. designed research, performed research, analyzed data, and wrote the paper.

  • The authors declare no conflict of interest.

  • This article is a PNAS Direct Submission.

  • Freely available online through the PNAS open access option.

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A randomized trial of the effect of estrogen and testosterone on economic behavior
Niklas Zethraeus, Ljiljana Kocoska-Maras, Tore Ellingsen, Bo von Schoultz, Angelica Lindén Hirschberg, Magnus Johannesson
Proceedings of the National Academy of Sciences Apr 2009, pnas.0812757106; DOI: 10.1073/pnas.0812757106

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A randomized trial of the effect of estrogen and testosterone on economic behavior
Niklas Zethraeus, Ljiljana Kocoska-Maras, Tore Ellingsen, Bo von Schoultz, Angelica Lindén Hirschberg, Magnus Johannesson
Proceedings of the National Academy of Sciences Apr 2009, pnas.0812757106; DOI: 10.1073/pnas.0812757106
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