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October 12, 2018

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    Alleviating catastrophic forgetting using context-dependent gating and synaptic stabilization
    Nicolas Y. Masse, Gregory D. Grant, and David J. Freedman
    PNAS published ahead of print October 12, 2018. https://doi.org/10.1073/pnas.1803839115

October 11, 2018

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    Highly disordered histone H1−DNA model complexes and their condensates
    Abigail L. Turner, Matthew Watson, Oscar G. Wilkins, Laura Cato, Andrew Travers, Jean O. Thomas, and Katherine Stott
    PNAS published ahead of print October 9, 2018. https://doi.org/10.1073/pnas.1805943115
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    RPA1 binding to NRF2 switches ARE-dependent transcriptional activation to ARE-NRE–dependent repression
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    PNAS published ahead of print October 11, 2018. https://doi.org/10.1073/pnas.1812125115
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    Ultrafast epithelial contractions provide insights into contraction speed limits and tissue integrity
    Shahaf Armon, Matthew Storm Bull, Andres Aranda-Diaz, and Manu Prakash
    PNAS published ahead of print October 11, 2018. https://doi.org/10.1073/pnas.1802934115
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    Discovery of a small-molecule inhibitor of specific serine residue BAD phosphorylation
    Vijay Pandey, Baocheng Wang, Chakrabhavi Dhananjaya Mohan, Ainiah Rushdiana Raquib, Shobith Rangappa, Venkatachalaiah Srinivasa, Julian E. Fuchs, Kesturu S. Girish, Tao Zhu, Andreas Bender, Lan Ma, Zhinan Yin, Basappa, Kanchugarakoppal S. Rangappa, and Peter E. Lobie
    PNAS published ahead of print October 11, 2018. https://doi.org/10.1073/pnas.1804897115
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    Thermodynamic favorability and pathway yield as evolutionary tradeoffs in biosynthetic pathway choice
    Bin Du, Daniel C. Zielinski, Jonathan M. Monk, and Bernhard O. Palsson
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    Nematic twist–bend phase in an external field
    Grzegorz Pająk, Lech Longa, and Agnieszka Chrzanowska
    PNAS published ahead of print October 11, 2018. https://doi.org/10.1073/pnas.1721786115
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    Navigating genetic diversity by painting the bacteria red
    Claire M. Palmer and Hal S. Alper
    PNAS published ahead of print October 11, 2018. https://doi.org/10.1073/pnas.1815763115
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    Stress response regulation and the hemodynamic response
    Katharine Dunlop and Conor Liston
    PNAS published ahead of print October 11, 2018. https://doi.org/10.1073/pnas.1814592115

October 10, 2018

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    XBP1s activation can globally remodel N-glycan structure distribution patterns
    Madeline Y. Wong, Kenny Chen, Aristotelis Antonopoulos, Brian T. Kasper, Mahender B. Dewal, Rebecca J. Taylor, Charles A. Whittaker, Pyae P. Hein, Anne Dell, Joseph C. Genereux, Stuart M. Haslam, Lara K. Mahal, and Matthew D. Shoulders
    PNAS published ahead of print October 10, 2018. https://doi.org/10.1073/pnas.1805425115
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    The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1
    Kirsten M. Knecht, Olga Buzovetsky, Constanze Schneider, Dominique Thomas, Vishok Srikanth, Lars Kaderali, Florentina Tofoleanu, Krystle Reiss, Nerea Ferreirós, Gerd Geisslinger, Victor S. Batista, Xiaoyun Ji, Jindrich Cinatl Jr., Oliver T. Keppler, and Yong Xiong
    PNAS published ahead of print October 10, 2018. https://doi.org/10.1073/pnas.1805593115
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    SUMO protease SENP1 deSUMOylates and stabilizes c-Myc
    Xiao-Xin Sun, Yingxiao Chen, Yulong Su, Xiaoyan Wang, Krishna Mohan Chauhan, Juan Liang, Colin J. Daniel, Rosalie C. Sears, and Mu-Shui Dai
    PNAS published ahead of print October 10, 2018. https://doi.org/10.1073/pnas.1802932115

October 09, 2018

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    Human mitochondrial degradosome prevents harmful mitochondrial R loops and mitochondrial genome instability
    Sonia Silva, Lola P. Camino, and Andrés Aguilera
    PNAS published ahead of print October 9, 2018. https://doi.org/10.1073/pnas.1807258115
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    mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3
    Guoli Shi, Stosh Ozog, Bruce E. Torbett, and Alex A. Compton
    PNAS published ahead of print October 9, 2018. https://doi.org/10.1073/pnas.1811892115
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    Molecular mechanism of activation of the immunoregulatory amidase NAAA
    Alexei Gorelik, Ahmad Gebai, Katalin Illes, Daniele Piomelli, and Bhushan Nagar
    PNAS published ahead of print October 9, 2018. https://doi.org/10.1073/pnas.1811759115
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    Redox-dependent niche differentiation provides evidence for multiple bacterial sources of glycerol tetraether lipids in lakes
    Yuki Weber, Jaap S. Sinninghe Damsté, Jakob Zopfi, Cindy De Jonge, Adrian Gilli, Carsten J. Schubert, Fabio Lepori, Moritz F. Lehmann, and Helge Niemann
    PNAS published ahead of print October 9, 2018. https://doi.org/10.1073/pnas.1805186115
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    Translating biased signaling in the ghrelin receptor system into differential in vivo functions
    Franziska Mende, Cecilie Hundahl, Bianca Plouffe, Louise Julie Skov, Bjørn Sivertsen, Andreas Nygaard Madsen, Michael Lückmann, Thi Ai Diep, Stefan Offermanns, Thomas Michael Frimurer, Michel Bouvier, and Birgitte Holst
    PNAS published ahead of print October 9, 2018. https://doi.org/10.1073/pnas.1804003115
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    Chronic social stress-induced hyperglycemia in mice couples individual stress susceptibility to impaired spatial memory
    Michael A. van der Kooij, Tanja Jene, Giulia Treccani, Isabelle Miederer, Annika Hasch, Nadine Voelxen, Stefan Walenta, and Marianne B. Müller
    PNAS published ahead of print October 9, 2018. https://doi.org/10.1073/pnas.1804412115
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    MmpL8MAB controls Mycobacterium abscessus virulence and production of a previously unknown glycolipid family
    Violaine Dubois, Albertus Viljoen, Laura Laencina, Vincent Le Moigne, Audrey Bernut, Faustine Dubar, Mickaël Blaise, Jean-Louis Gaillard, Yann Guérardel, Laurent Kremer, Jean-Louis Herrmann, and Fabienne Girard-Misguich
    PNAS published ahead of print October 9, 2018. https://doi.org/10.1073/pnas.1812984115
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    Activity-dependent bulk endocytosis proteome reveals a key presynaptic role for the monomeric GTPase Rab11
    A. C. Kokotos, J. Peltier, E. C. Davenport, M. Trost, and M. A. Cousin
    PNAS published ahead of print October 9, 2018. https://doi.org/10.1073/pnas.1809189115

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