PNAS -- Table of Contents (Jun 10 2003, 100 (12))

Cover

Table of Contents

June 10, 2003; 100 (12) [Index By Author] [Cover Photo]

FROM THE COVER

Pseudo-cryptic speciation of calcifying algae

Architecture of initiation in the structure RNAPII (A)

Architecture of initiation in the structure RNAPII (B)

Decoy in pocket disables dengue

Houseguests, parasites, and speciation in ants

Developing receptor antagonists by virtual screening

COMMENTARIES

PHYSICAL SCIENCES
    Applied Mathematics
    Chemistry
    Mathematics
    Physics

SOCIAL SCIENCES
Anthropology
Psychology

BIOLOGICAL SCIENCES
    Applied Biological Sciences
    Biochemistry
    Biophysics
    Cell Biology
    Developmental Biology
    Ecology
    Evolution
    Genetics

    Immunology
    Medical Sciences
    Microbiology
    Neuroscience
    Pharmacology
    Physiology
    Plant Biology
    Population Biology

CORRECTIONS

Access PNAS articles and abstracts: Instruction

COMMENTARIES

Francisco J. Asturias and John L. Craighead: RNA polymerase II at initiation
PNAS 2003 100: 6893-6895; published online on June 2, 2003, 10.1073/pnas.1332606100 [Extract] [Full Text] [PDF]
See companion article on page 6964
See companion article on page 6969

Stewart H. Berlocher: When houseguests become parasites: Sympatric speciation in ants
PNAS 2003 100: 6896-6898; published online on June 2, 2003, 10.1073/pnas.1332533100 [Extract] [Full Text] [PDF]
See companion article on page 7169

Félix A. Rey: Dengue virus envelope glycoprotein structure: New insight into its interactions during viral entry
PNAS 2003 100: 6899-6901; published online on June 2, 2003, 10.1073/pnas.1332695100 [Extract] [Full Text] [PDF]
See companion article on page 6986

John T. Koh: Making virtual screening a reality
PNAS 2003 100: 6902-6903; published online on June 2, 2003, 10.1073/pnas.1332743100 [Extract] [Full Text] [PDF]
See companion article on page 7354

PHYSICAL SCIENCES

Applied Mathematics

Jeremy Lovejoy and Ken Ono: Hypergeometric generating functions for values of Dirichlet and other L functions
PNAS 2003 100: 6904-6909; published online on May 19, 2003, 10.1073/pnas.1131697100 [Abstract] [Full Text] [PDF]

Chemistry

Michael Oberhuber, Joachim Berghold, Kathrin Breuker, Stefan Hörtensteiner, and Bernhard Kraütler: Breakdown of chlorophyll: A nonenzymatic reaction accounts for the formation of the colorless "nonfluorescent" chlorophyll catabolites
PNAS 2003 100: 6910-6915; published online on May 30, 2003, 10.1073/pnas.1232207100 [Abstract] [Full Text] [PDF] [Supporting Information]

Julia Kubanek, Paul R. Jensen, Paul A. Keifer, M. Cameron Sullards, Dwight O. Collins, and William Fenical: Seaweed resistance to microbial attack: A targeted chemical defense against marine fungi
PNAS 2003 100: 6916-6921; published online on May 19, 2003, 10.1073/pnas.1131855100 [Abstract] [Full Text] [PDF] [Supporting Table]

Mathematics

Jochen Denzler and Robert J. McCann: Phase transitions and symmetry breaking in singular diffusion
PNAS 2003 100: 6922-6925; published online on May 23, 2003, 10.1073/pnas.1231896100 [Abstract] [Full Text] [PDF]

Physics

Jan M. Kriegl, Karin Nienhaus, Pengchi Deng, Jochen Fuchs, and G. Ulrich Nienhaus: Ligand dynamics in a protein internal cavity
PNAS 2003 100: 7069-7074; published online on May 28, 2003, 10.1073/pnas.1231856100 [Abstract] [Full Text] [PDF]

SOCIAL SCIENCES

Anthropology

Timothy D. Weaver: The shape of the Neandertal femur is primarily the consequence of a hyperpolar body form
PNAS 2003 100: 6926-6929; published online on May 21, 2003, 10.1073/pnas.1232340100 [Abstract] [Full Text] [PDF] [Supporting Table]

Takeshi Nishimura, Akichika Mikami, Juri Suzuki, and Tetsuro Matsuzawa: Descent of the larynx in chimpanzee infants
PNAS 2003 100: 6930-6933; published online on May 29, 2003, 10.1073/pnas.1231107100 [Abstract] [Full Text] [PDF]

Derek E. Wildman, Monica Uddin, Guozhen Liu, Lawrence I. Grossman, and Morris Goodman
Inaugural Article by a Recently Elected Academy Member:
Inaugural Article: Implications of natural selection in shaping 99.4% nonsynonymous DNA identity between humans and chimpanzees: Enlarging genus Homo
PNAS 2003 100: 7181-7188; published online on May 23, 2003, 10.1073/pnas.1232172100 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]

Psychology

Jin Fan, John Fossella, Tobias Sommer, Yanghong Wu, and Michael I. Posner: Mapping the genetic variation of executive attention onto brain activity
PNAS 2003 100: 7406-7411; published online on May 28, 2003, 10.1073/pnas.0732088100 [Abstract] [Full Text] [PDF]

Myeong-Ho Sohn, Adam Goode, V. Andrew Stenger, Cameron S. Carter, and John R. Anderson: Competition and representation during memory retrieval: Roles of the prefrontal cortex and the posterior parietal cortex
PNAS 2003 100: 7412-7417; published online on May 28, 2003, 10.1073/pnas.0832374100 [Abstract] [Full Text] [PDF]

BIOLOGICAL SCIENCES

Applied Biological Sciences

Mark X. Yang, Bhami Shenoy, Matthew Disttler, Reena Patel, Margaret McGrath, Sergey Pechenov, and Alexey L. Margolin: Crystalline monoclonal antibodies for subcutaneous delivery
PNAS 2003 100: 6934-6939; published online on June 2, 2003, 10.1073/pnas.1131899100 [Abstract] [Full Text] [PDF] [Supporting Information]

Scott A. Gerber, John Rush, Olaf Stemman, Marc W. Kirschner, and Steven P. Gygi: Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS
PNAS 2003 100: 6940-6945; published online on May 27, 2003, 10.1073/pnas.0832254100 [Abstract] [Full Text] [PDF] [SupportingMethods and Methods]

Chuanbin Mao, Christine E. Flynn, Andrew Hayhurst, Rozamond Sweeney, Jifa Qi, George Georgiou, Brent Iverson, and Angela M. Belcher: Viral assembly of oriented quantum dot nanowires
PNAS 2003 100: 6946-6951; published online on May 30, 2003, 10.1073/pnas.0832310100 [Abstract] [Full Text] [PDF] [Supporting Information]

Robert J. Cousins, Raymond K. Blanchard, Michael P. Popp, Li Liu, Jay Cao, J. Bernadette Moore, and Calvert L. Green: A global view of the selectivity of zinc deprivation and excess on genes expressed in human THP-1 mononuclear cells
PNAS 2003 100: 6952-6957; published online on May 19, 2003, 10.1073/pnas.0732111100 [Abstract] [Full Text] [PDF] [Supporting Information]

James R. Vasselli, Joanna H. Shih, Shuba R. Iyengar, Jodi Maranchie, Joseph Riss, Robert Worrell, Carlos Torres-Cabala, Ray Tabios, Andra Mariotti, Robert Stearman, Maria Merino, McClellan M. Walther, Richard Simon, Richard D. Klausner, and W. Marston Linehan: Predicting survival in patients with metastatic kidney cancer by gene-expression profiling in the primary tumor
PNAS 2003 100: 6958-6963; published online on May 30, 2003, 10.1073/pnas.1131754100 [Abstract] [Full Text] [PDF] [Supporting Information]

Biochemistry

Karim-Jean Armache, Hubert Kettenberger, and Patrick Cramer: Architecture of initiation-competent 12-subunit RNA polymerase II
PNAS 2003 100: 6964-6968; published online on May 13, 2003, 10.1073/pnas.1030608100 [Abstract] [Full Text] [PDF]
See Commentary on page 6893

David A. Bushnell and Roger D. Kornberg
Complete, 12-subunit RNA polymerase II at 4.1-Å resolution: Implications for the initiation of transcription
PNAS 2003 100: 6969-6973; published online on May 13, 2003, 10.1073/pnas.1130601100 [Abstract] [Full Text] [PDF] [Supporting Figures]
See Commentary on page 6893

Yang-Gyun Kim, Maneesha Muralinath, Teresa Brandt, Matthew Pearcy, Kevin Hauns, Ky Lowenhaupt, Bertram L. Jacobs, and Alexander Rich: A role for Z-DNA binding in vaccinia virus pathogenesis
PNAS 2003 100: 6974-6979; published online on May 30, 2003, 10.1073/pnas.0431131100 [Abstract] [Full Text] [PDF] [Supporting Text]

Thomas H. Rod, Jennifer L. Radkiewicz, and Charles L. Brooks, III: Correlated motion and the effect of distal mutations in dihydrofolate reductase
PNAS 2003 100: 6980-6985; published online on May 19, 2003, 10.1073/pnas.1230801100 [Abstract] [Full Text] [PDF] [Supporting Information]

Yorgo Modis, Steven Ogata, David Clements, and Stephen C. Harrison
A ligand-binding pocket in the dengue virus envelope glycoprotein
PNAS 2003 100: 6986-6991; published online on May 20, 2003, 10.1073/pnas.0832193100 [Abstract] [Full Text] [PDF]
See Commentary on page 6899

Babu A. Manjasetty, Justin Powlowski, and Alice Vrielink: Crystal structure of a bifunctional aldolase–dehydrogenase: Sequestering a reactive and volatile intermediate
PNAS 2003 100: 6992-6997; published online on May 22, 2003, 10.1073/pnas.1236794100 [Abstract] [Full Text] [PDF]

Victor Guallar, Mu-Hyun Baik, Stephen J. Lippard, and Richard A. Friesner: Peripheral heme substituents control the hydrogen-atom abstraction chemistry in cytochromes P450
PNAS 2003 100: 6998-7002; published online on May 27, 2003, 10.1073/pnas.0732000100 [Abstract] [Full Text] [PDF]

Bernd Hoffmann, G. Thomas Mitchell, Patrick Gendron, François Major, Angela A. Andersen, Richard A. Collins, and Pascale Legault: NMR structure of the active conformation of the Varkud satellite ribozyme cleavage site
PNAS 2003 100: 7003-7008; published online on June 2, 2003, 10.1073/pnas.0832440100 [Abstract] [Full Text] [PDF] [Supporting Figures]

Chang-yun Gui and Ann Dean: A major role for the TATA box in recruitment of chromatin modifying complexes to a globin gene promoter
PNAS 2003 100: 7009-7014; published online on May 28, 2003, 10.1073/pnas.1236499100 [Abstract] [Full Text] [PDF] [Supporting Figures]

Yingqi Gu, Z. Hong Zhou, Diane B. McCarthy, Lester J. Reed, and James K. Stoops: 3D electron microscopy reveals the variable deposition and protein dynamics of the peripheral pyruvate dehydrogenase component about the core
PNAS 2003 100: 7015-7020; published online on May 19, 2003, 10.1073/pnas.0732060100 [Abstract] [Full Text] [PDF]

P. B. Stathopulos, J. A. O. Rumfeldt, G. A. Scholz, R. A. Irani, H. E. Frey, R. A. Hallewell, J. R. Lepock, and E. M. Meiering: Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis show enhanced formation of aggregates in vitro
PNAS 2003 100: 7021-7026; published online on May 28, 2003, 10.1073/pnas.1237797100 [Abstract] [Full Text] [PDF]

Cameron G. Lait, Hans T. Alborn, Peter E. A. Teal, and James H. Tumlinson, III: Rapid biosynthesis of N-linolenoyl-L-glutamine, an elicitor of plant volatiles, by membrane-associated enzyme(s) in Manduca sexta
PNAS 2003 100: 7027-7032; published online on May 28, 2003, 10.1073/pnas.1232474100 [Abstract] [Full Text] [PDF]

Youkyung Hwang Choi and Curt H. Hagedorn: Purifying mRNAs with a high-affinity eIF4E mutant identifies the short 3' poly(A) end phenotype
PNAS 2003 100: 7033-7038; published online on May 30, 2003, 10.1073/pnas.1232347100 [Abstract] [Full Text] [PDF] [Supporting Tables]

Biophysics

Shin-ichi Adachi, Sam-Yong Park, Jeremy R. H. Tame, Yoshitsugu Shiro, and Naoya Shibayama: Direct observation of photolysis-induced tertiary structural changes in hemoglobin
PNAS 2003 100: 7039-7044; published online on May 28, 2003, 10.1073/pnas.1230629100 [Abstract] [Full Text] [PDF]

Vincent R. Harley, Sharon Layfield, Claire L. Mitchell, Jade K. Forwood, Anna P. John, Lyndall J. Briggs, Sharon G. McDowall, and David A. Jans: Defective importin ${beta}$ recognition and nuclear import of the sex-determining factor SRY are associated with XY sex-reversing mutations
PNAS 2003 100: 7045-7050; published online on May 22, 2003, 10.1073/pnas.1137864100 [Abstract] [Full Text] [PDF]

Jean-Christophe Leloup and Albert Goldbeter: Toward a detailed computational model for the mammalian circadian clock
PNAS 2003 100: 7051-7056; published online on May 29, 2003, 10.1073/pnas.1132112100 [Abstract] [Full Text] [PDF] [Supporting Information]

Joan J. Englander, Charyl Del Mar, Will Li, S. Walter Englander, Jack S. Kim, David D. Stranz, Yoshitomo Hamuro, and Virgil L. Woods, Jr.: Protein structure change studied by hydrogen-deuterium exchange, functional labeling, and mass spectrometry
PNAS 2003 100: 7057-7062; published online on May 28, 2003, 10.1073/pnas.1232301100 [Abstract] [Full Text] [PDF] [Supporting Tables]

Oliver Beckstein and Mark S. P. Sansom: Liquid–vapor oscillations of water in hydrophobic nanopores
PNAS 2003 100: 7063-7068; published online on May 9, 2003, 10.1073/pnas.1136844100 [Abstract] [Full Text] [PDF] [Supporting Table]

Jan M. Kriegl, Karin Nienhaus, Pengchi Deng, Jochen Fuchs, and G. Ulrich Nienhaus: Ligand dynamics in a protein internal cavity
PNAS 2003 100: 7069-7074; published online on May 28, 2003, 10.1073/pnas.1231856100 [Abstract] [Full Text] [PDF]

Warren R. Zipfel, Rebecca M. Williams, Richard Christie, Alexander Yu Nikitin, Bradley T. Hyman, and Watt W. Webb: Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation
PNAS 2003 100: 7075-7080; published online on May 19, 2003, 10.1073/pnas.0832308100 [Abstract] [Full Text] [PDF] [Supporting Text]

Daniel A. Dombeck, Karl A. Kasischke, Harshad D. Vishwasrao, Martin Ingelsson, Bradley T. Hyman, and Watt W. Webb: Uniform polarity microtubule assemblies imaged in native brain tissue by second-harmonic generation microscopy
PNAS 2003 100: 7081-7086; published online on May 23, 2003, 10.1073/pnas.0731953100 [Abstract] [Full Text] [PDF] [Supporting Movies]

Bianxiao Cui, Min-Yi Shen, and Karl F. Freed: Folding and misfolding of the papillomavirus E6 interacting peptide E6ap
PNAS 2003 100: 7087-7092; published online on May 27, 2003, 10.1073/pnas.0431214100 [Abstract] [Full Text] [PDF]

Cell Biology

Susanne I. Wells, Bruce J. Aronow, Trisha M. Wise, Sarah S. Williams, Jennifer A. Couget, and Peter M. Howley: Transcriptome signature of irreversible senescence in human papillomavirus-positive cervical cancer cells
PNAS 2003 100: 7093-7098; published online on May 19, 2003, 10.1073/pnas.1232309100 [Abstract] [Full Text] [PDF]

Livnat Lopian, Anat Nussbaum-Shochat, Kathryn O'Day-Kerstein, Andrew Wright, and Orna Amster-Choder: The BglF sensor recruits the BglG transcription regulator to the membrane and releases it on stimulation
PNAS 2003 100: 7099-7104; published online on May 27, 2003, 10.1073/pnas.1037608100 [Abstract] [Full Text] [PDF] [Supporting Information]

Xin-Liang Zhou, Ann F. Batiza, Stephen H. Loukin, Chris P. Palmer, Ching Kung, and Yoshiro Saimi: The transient receptor potential channel on the yeast vacuole is mechanosensitive
PNAS 2003 100: 7105-7110; published online on May 27, 2003, 10.1073/pnas.1230540100 [Abstract] [Full Text] [PDF]

Christoph Handschin, James Rhee, Jiandie Lin, Paul T. Tarr, and Bruce M. Spiegelman: An autoregulatory loop controls peroxisome proliferator-activated receptor ${gamma}$ coactivator 1 ${alpha}$ expression in muscle
PNAS 2003 100: 7111-7116; published online on May 22, 2003, 10.1073/pnas.1232352100 [Abstract] [Full Text] [PDF]

Developmental Biology

Anandwardhan A. Hardikar, Bernice Marcus-Samuels, Elizabeth Geras-Raaka, Bruce M. Raaka, and Marvin C. Gershengorn: Human pancreatic precursor cells secrete FGF2 to stimulate clustering into hormone-expressing islet-like cell aggregates
PNAS 2003 100: 7117-7122; published online on May 30, 2003, 10.1073/pnas.1232230100 [Abstract] [Full Text] [PDF] [Supporting Information]

Yi Lisa Lyu and James C. Wang: Aberrant lamination in the cerebral cortex of mouse embryos lacking DNA topoisomerase II ${beta}$
PNAS 2003 100: 7123-7128; published online on May 28, 2003, 10.1073/pnas.1232376100 [Abstract] [Full Text] [PDF]

Zhigao Wang, Da-Zhi Wang, G. C. Teg Pipes, and Eric N. Olson: Myocardin is a master regulator of smooth muscle gene expression
PNAS 2003 100: 7129-7134; published online on May 19, 2003, 10.1073/pnas.1232341100 [Abstract] [Full Text] [PDF]

Felix A. Mic, Andrei Molotkov, Doris M. Benbrook, and Gregg Duester: Retinoid activation of retinoic acid receptor but not retinoid X receptor is sufficient to rescue lethal defect in retinoic acid synthesis
PNAS 2003 100: 7135-7140; published online on June 2, 2003, 10.1073/pnas.1231422100 [Abstract] [Full Text] [PDF]

Ecology

Julia Kubanek, Paul R. Jensen, Paul A. Keifer, M. Cameron Sullards, Dwight O. Collins, and William Fenical: Seaweed resistance to microbial attack: A targeted chemical defense against marine fungi
PNAS 2003 100: 6916-6921; published online on May 19, 2003, 10.1073/pnas.1131855100 [Abstract] [Full Text] [PDF] [Supporting Table]

Bainian Sun, David L. Dilcher, David J. Beerling, Chengjun Zhang, Defei Yan, and Elizabeth Kowalski: Variation in Ginkgo biloba L. leaf characters across a climatic gradient in China
PNAS 2003 100: 7141-7146; published online on May 30, 2003, 10.1073/pnas.1232419100 [Abstract] [Full Text] [PDF]

Paul R. Armsworth and Joan E. Roughgarden: The economic value of ecological stability
PNAS 2003 100: 7147-7151; published online on May 30, 2003, 10.1073/pnas.0832226100 [Abstract] [Full Text] [PDF]

Evolution

Joshua B. Plotkin and Jonathan Dushoff: Codon bias and frequency-dependent selection on the hemagglutinin epitopes of influenza A virus
PNAS 2003 100: 7152-7157; published online on May 14, 2003, 10.1073/pnas.1132114100 [Abstract] [Full Text] [PDF] [Supporting Table]

Scott W. Roy, Alexei Fedorov, and Walter Gilbert: Large-scale comparison of intron positions in mammalian genes shows intron loss but no gain
PNAS 2003 100: 7158-7162; published online on May 30, 2003, 10.1073/pnas.1232297100 [Abstract] [Full Text] [PDF]

Alberto G. Sáez, Ian Probert, Markus Geisen, Patrick Quinn, Jeremy R. Young, and Linda K. Medlin
Pseudo-cryptic speciation in coccolithophores
PNAS 2003 100: 7163-7168; published online on May 20, 2003, 10.1073/pnas.1132069100 [Abstract] [Full Text] [PDF]

Riitta Savolainen and Kari Vepsäläinen
Sympatric speciation through intraspecific social parasitism
PNAS 2003 100: 7169-7174; published online on May 9, 2003, 10.1073/pnas.1036825100 [Abstract] [Full Text] [PDF] [Supporting Information]
See Commentary on page 6896

Miriam H. Richards, Eric J. von Wettberg, and Amy C. Rutgers: A novel social polymorphism in a primitively eusocial bee
PNAS 2003 100: 7175-7180; published online on May 30, 2003, 10.1073/pnas.1030738100 [Abstract] [Full Text] [PDF] [Supporting Table]

Genetics

Wei Yan, Amir H. Assadi, Anthony Wynshaw-Boris, Gregor Eichele, Martin M. Matzuk, and Gary D. Clark: Previously uncharacterized roles of platelet-activating factor acetylhydrolase 1b complex in mouse spermatogenesis
PNAS 2003 100: 7189-7194; published online on May 29, 2003, 10.1073/pnas.1236145100 [Abstract] [Full Text] [PDF]

Victor M. Miller, Haibin Xia, Ginger L. Marrs, Cynthia M. Gouvion, Gloria Lee, Beverly L. Davidson, and Henry L. Paulson: Allele-specific silencing of dominant disease genes
PNAS 2003 100: 7195-7200; published online on June 2, 2003, 10.1073/pnas.1231012100 [Abstract] [Full Text] [PDF] [Supporting Figure]

Sook Shin and Inder M. Verma: BRCA2 cooperates with histone acetyltransferases in androgen receptor-mediated transcription
PNAS 2003 100: 7201-7206; published online on May 19, 2003, 10.1073/pnas.1132020100 [Abstract] [Full Text] [PDF]

Daiguan Yu, James A. Sawitzke, Hilary Ellis, and Donald L. Court: Recombineering with overlapping single-stranded DNA oligonucleotides: Testing a recombination intermediate
PNAS 2003 100: 7207-7212; published online on May 27, 2003, 10.1073/pnas.1232375100 [Abstract] [Full Text] [PDF]

Gyanu Lamichhane, Matteo Zignol, Natalie J. Blades, Deborah E. Geiman, Annette Dougherty, Jacques Grosset, Karl W. Broman, and William R. Bishai: A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: Application to Mycobacterium tuberculosis
PNAS 2003 100: 7213-7218; published online on May 29, 2003, 10.1073/pnas.1231432100 [Abstract] [Full Text] [PDF] [Supporting Tables]

Géraldine Mathonnet, Caroline Léger, Julie Desnoyers, Régen Drouin, Jean-Philippe Therrien, and Elliot A. Drobetsky: UV wavelength-dependent regulation of transcription-coupled nucleotide excision repair in p53-deficient human cells
PNAS 2003 100: 7219-7224; published online on May 29, 2003, 10.1073/pnas.1232161100 [Abstract] [Full Text] [PDF]

Yaning Yang, Jingshan Zhang, Josephine Hoh, Fumihiko Matsuda, Peng Xu, Mark Lathrop, and Jurg Ott: Efficiency of single-nucleotide polymorphism haplotype estimation from pooled DNA
PNAS 2003 100: 7225-7230; published online on May 30, 2003, 10.1073/pnas.1237858100 [Abstract] [Full Text] [PDF]

Immunology

Timothy W. Secomb, Moritz A. Konerding, Charles A. West, Mei Su, Alan J. Young, and Steven J. Mentzer: Microangiectasias: Structural regulators of lymphocyte transmigration
PNAS 2003 100: 7231-7234; published online on June 2, 2003, 10.1073/pnas.1232173100 [Abstract] [Full Text] [PDF] [Supporting Movie]

Richard J. Webby, Samita Andreansky, John Stambas, Jerold E. Rehg, Robert G. Webster, Peter C. Doherty, and Stephen J. Turner: Protection and compensation in the influenza virus-specific CD8⁺ T cell response
PNAS 2003 100: 7235-7240; published online on May 29, 2003, 10.1073/pnas.1232449100 [Abstract] [Full Text] [PDF]

Jürgen Roes, B. Ken Choi, and Balthazar B. Cazac: Redirection of B cell responsiveness by transforming growth factor ${beta}$ receptor
PNAS 2003 100: 7241-7246; published online on May 28, 2003, 10.1073/pnas.0731875100 [Abstract] [Full Text] [PDF] [Supporting Figure]

Medical Sciences

Kiyoko Yoshioka, Victoria Foletta, Ora Bernard, and Kazuyuki Itoh: A role for LIM kinase in cancer invasion
PNAS 2003 100: 7247-7252; published online on May 30, 2003, 10.1073/pnas.1232344100 [Abstract] [Full Text] [PDF] [Supporting Figure]

Michal Zalzman, Sanjeev Gupta, Ranjit K. Giri, Irina Berkovich, Baljit S. Sappal, Ohad Karnieli, Mark A. Zern, Norman Fleischer, and Shimon Efrat: Reversal of hyperglycemia in mice by using human expandable insulin-producing cells differentiated from fetal liver progenitor cells
PNAS 2003 100: 7253-7258; published online on May 19, 2003, 10.1073/pnas.1136854100 [Abstract] [Full Text] [PDF] [Supporting Table]

Kojo S. J. Elenitoba-Johnson, Stephen D. Jenson, Robert T. Abbott, Robert A. Palais, Sandra D. Bohling, Zhaosheng Lin, Sheryl Tripp, Paul J. Shami, Lai Y. Wang, Robert W. Coupland, Rena Buckstein, Bayardo Perez-Ordonez, Sherrie L. Perkins, Ian D. Dube, and Megan S. Lim: Involvement of multiple signaling pathways in follicular lymphoma transformation: p38-mitogen-activated protein kinase as a target for therapy
PNAS 2003 100: 7259-7264; published online on May 19, 2003, 10.1073/pnas.1137463100 [Abstract] [Full Text] [PDF] [Supporting Information]

Peter Sartipy and David J. Loskutoff: Monocyte chemoattractant protein 1 in obesity and insulin resistance
PNAS 2003 100: 7265-7270; published online on May 19, 2003, 10.1073/pnas.1133870100 [Abstract] [Full Text] [PDF] [Supporting Information]

Mayla Hsu, Jie Zhang, Mike Flint, Carine Logvinoff, Cecilia Cheng-Mayer, Charles M. Rice, and Jane A. McKeating: Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles
PNAS 2003 100: 7271-7276; published online on May 21, 2003, 10.1073/pnas.0832180100 [Abstract] [Full Text] [PDF]

A. Santana, E. Salido, A. Torres, and L. J. Shapiro: Primary hyperoxaluria type 1 in the Canary Islands: A conformational disease due to I244T mutation in the P11L-containing alanine:glyoxylate aminotransferase
PNAS 2003 100: 7277-7282; published online on May 30, 2003, 10.1073/pnas.1131968100 [Abstract] [Full Text] [PDF]

Anne Braun, Songwen Zhang, Helena E. Miettinen, Shamsah Ebrahim, Teresa M. Holm, Eliza Vasile, Mark J. Post, Danita M. Yoerger, Michael H. Picard, Joshua L. Krieger, Nancy C. Andrews, Michael Simons, and Monty Krieger: Probucol prevents early coronary heart disease and death in the high-density lipoprotein receptor SR-BI/apolipoprotein E double knockout mouse
PNAS 2003 100: 7283-7288; published online on May 27, 2003, 10.1073/pnas.1237725100 [Abstract] [Full Text] [PDF]

Microbiology

Julie K. Pfeiffer and Karla Kirkegaard: A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity
PNAS 2003 100: 7289-7294; published online on May 16, 2003, 10.1073/pnas.1232294100 [Abstract] [Full Text] [PDF]

Helen C. Schreiner, Kathy Sinatra, Jeffrey B. Kaplan, David Furgang, Scott C. Kachlany, Paul J. Planet, Brenda A. Perez, David H. Figurski, and Daniel H. Fine: Tight-adherence genes of Actinobacillus actinomycetemcomitans are required for virulence in a rat model
PNAS 2003 100: 7295-7300; published online on May 19, 2003, 10.1073/pnas.1237223100 [Abstract] [Full Text] [PDF]

Jenifer Coburn and Carla Cugini: Targeted mutation of the outer membrane protein P66 disrupts attachment of the Lyme disease agent, Borrelia burgdorferi, to integrin ${alpha}$ _v ${beta}$ ₃
PNAS 2003 100: 7301-7306; published online on May 14, 2003, 10.1073/pnas.1131117100 [Abstract] [Full Text] [PDF] [Supporting Information]

Joshua R. Fischer, Nikhat Parveen, Loranne Magoun, and John M. Leong: Decorin-binding proteins A and B confer distinct mammalian cell type-specific attachment by Borrelia burgdorferi, the Lyme disease spirochete
PNAS 2003 100: 7307-7312; published online on May 28, 2003, 10.1073/pnas.1231043100 [Abstract] [Full Text] [PDF]

Samuel Karlin, Melanie J. Barnett, Allan M. Campbell, Robert F. Fisher, and Jan Mrázek: Predicting gene expression levels from codon biases in ${alpha}$ -proteobacterial genomes
PNAS 2003 100: 7313-7318; published online on May 29, 2003, 10.1073/pnas.1232298100 [Abstract] [Full Text] [PDF] [Supporting Information]

Neuroscience

Christoph Stosiek, Olga Garaschuk, Knut Holthoff, and Arthur Konnerth: In vivo two-photon calcium imaging of neuronal networks
PNAS 2003 100: 7319-7324; published online on May 30, 2003, 10.1073/pnas.1232232100 [Abstract] [Full Text] [PDF]

Laura Calzà, Alessandro Giuliani, Mercedes Fernandez, Stefania Pirondi, Giulia D'Intino, Luigi Aloe, and Luciana Giardino: Neural stem cells and cholinergic neurons: Regulation by immunolesion and treatment with mitogens, retinoic acid, and nerve growth factor
PNAS 2003 100: 7325-7330; published online on May 30, 2003, 10.1073/pnas.1132092100 [Abstract] [Full Text] [PDF]

Trudy G. Oliver, Linda L. Grasfeder, Audra L. Carroll, Constanze Kaiser, Christine L. Gillingham, Simon M. Lin, Rasika Wickramasinghe, Matthew P. Scott, and Robert J. Wechsler-Reya: Transcriptional profiling of the Sonic hedgehog response: A critical role for N-myc in proliferation of neuronal precursors
PNAS 2003 100: 7331-7336; published online on May 30, 2003, 10.1073/pnas.0832317100 [Abstract] [Full Text] [PDF] [Supporting Information]

Patrizia Tosetti, Narendra Pathak, Michele H. Jacob, and Kathleen Dunlap: RGS3 mediates a calcium-dependent termination of G protein signaling in sensory neurons
PNAS 2003 100: 7337-7342; published online on May 27, 2003, 10.1073/pnas.1231837100 [Abstract] [Full Text] [PDF]

Jürgen Tautz, Sven Maier, Claudia Groh, Wolfgang Rössler, and Axel Brockmann: Behavioral performance in adult honey bees is influenced by the temperature experienced during their pupal development
PNAS 2003 100: 7343-7347; published online on May 22, 2003, 10.1073/pnas.1232346100 [Abstract] [Full Text] [PDF]

Sheila Nirenberg and Peter E. Latham: Decoding neuronal spike trains: How important are correlations?
PNAS 2003 100: 7348-7353; published online on May 29, 2003, 10.1073/pnas.1131895100 [Abstract] [Full Text] [PDF] [Supporting Infomation]

Pharmacology

Matthieu Schapira, Bruce M. Raaka, Sharmistha Das, Li Fan, Maxim Totrov, Zhiguo Zhou, Stephen R. Wilson, Ruben Abagyan, and Herbert H. Samuels: Discovery of diverse thyroid hormone receptor antagonists by high-throughput docking
PNAS 2003 100: 7354-7359; published online on May 30, 2003, 10.1073/pnas.1131854100 [Abstract] [Full Text] [PDF] [Supporting Information]
See Commentary on page 6902

Physiology

Mariko Hara and A. S. Verkman: Glycerol replacement corrects defective skin hydration, elasticity, and barrier function in aquaporin-3-deficient mice
PNAS 2003 100: 7360-7365; published online on May 27, 2003, 10.1073/pnas.1230416100 [Abstract] [Full Text] [PDF]

Joseph F. Hoffman, William Joiner, Keith Nehrke, Olga Potapova, Kristen Foye, and Amittha Wickrema: The hSK4 (KCNN4) isoform is the Ca²⁺-activated K⁺ channel (Gardos channel) in human red blood cells
PNAS 2003 100: 7366-7371; published online on May 28, 2003, 10.1073/pnas.1232342100 [Abstract] [Full Text] [PDF]

Gabriël J. L. Beckers, Roderick A. Suthers, and Carel ten Cate: Pure-tone birdsong by resonance filtering of harmonic overtones
PNAS 2003 100: 7372-7376; published online on May 22, 2003, 10.1073/pnas.1232227100 [Abstract] [Full Text] [PDF]

Akira Tsujino, Chantal Maertens, Kinji Ohno, Xin-Ming Shen, Taku Fukuda, C. Michael Harper, Stephen C. Cannon, and Andrew G. Engel: Myasthenic syndrome caused by mutation of the SCN4A sodium channel
PNAS 2003 100: 7377-7382; published online on May 23, 2003, 10.1073/pnas.1230273100 [Abstract] [Full Text] [PDF]

Plant Biology

Michael Oberhuber, Joachim Berghold, Kathrin Breuker, Stefan Hörtensteiner, and Bernhard Kraütler: Breakdown of chlorophyll: A nonenzymatic reaction accounts for the formation of the colorless "nonfluorescent" chlorophyll catabolites
PNAS 2003 100: 6910-6915; published online on May 30, 2003, 10.1073/pnas.1232207100 [Abstract] [Full Text] [PDF] [Supporting Information]

Matias Kirst, Arthur F. Johnson, Christie Baucom, Erin Ulrich, Kristy Hubbard, Rod Staggs, Charles Paule, Ernest Retzel, Ross Whetten, and Ronald Sederoff: Apparent homology of expressed genes from wood-forming tissues of loblolly pine (Pinus taeda L.) with Arabidopsis thaliana
PNAS 2003 100: 7383-7388; published online on May 27, 2003, 10.1073/pnas.1132171100 [Abstract] [Full Text] [PDF] [Supporting Table]

Enrique Rojo, Jan Zouhar, Clay Carter, Valentina Kovaleva, and Natasha V. Raikhel: A unique mechanism for protein processing and degradation in Arabidopsis thaliana
PNAS 2003 100: 7389-7394; published online on May 28, 2003, 10.1073/pnas.1230987100 [Abstract] [Full Text] [PDF]

Motoyasu Adachi, Jiro Kanamori, Taro Masuda, Kazuhiro Yagasaki, Keisuke Kitamura, Bunzo Mikami, and Shigeru Utsumi: Crystal structure of soybean 11S globulin: Glycinin A3B4 homohexamer
PNAS 2003 100: 7395-7400; published online on May 27, 2003, 10.1073/pnas.0832158100 [Abstract] [Full Text] [PDF]