Find articles in this issue containing these words:

COMMENTARIES

Áine McKnight and Robin A. Weiss

Blocking the docking of HIV-1
PNAS 2003 100: 10581-10582; published online before print September 8 2003, 10.1073/pnas.2035071100 [Extract] [Full Text] [PDF]  
See companion article on page 11013

Jonatha M. Gott

Two distinct roles for terminal uridylyl transferases in RNA editing
PNAS 2003 100: 10583-10584; published online before print September 8 2003, 10.1073/pnas.2035062100 [Extract] [Full Text] [PDF]  
See companion article on page 10617

Gregory Z. Ferl, John M. Timmerman, and Owen N. Witte From the Cover: Extending the utility of gene profiling data by bridging microarray platforms PNAS 2003 100: 10585-10587; published online before print September 8 2003, 10.1073/pnas.2034937100 [Extract] [Full Text] [PDF]

Gregory R. Mundy

Endothelin-1 and osteoblastic metastasis
PNAS 2003 100: 10588-10589; published online before print September 8 2003, 10.1073/pnas.2035063100 [Extract] [Full Text] [PDF]  
See companion article on page 10954

Charles Noussair

Innovations in the design of bundled-item auctions
PNAS 2003 100: 10590-10591; published online before print September 8 2003, 10.1073/pnas.1934705100 [Extract] [Full Text] [PDF]  
See companion article on page 11153

PERSPECTIVES

Stephen J. Gould, Amy M. Booth, and James E. K. Hildreth

The Trojan exosome hypothesis
PNAS 2003 100: 10592-10597; published online before print August 28 2003, 10.1073/pnas.1831413100 [Abstract] [Full Text] [PDF] [Supporting Information]  

John P. Moore and Robert W. Doms

The entry of entry inhibitors: A fusion of science and medicine
PNAS 2003 100: 10598-10602; published online before print September 5 2003, 10.1073/pnas.1932511100 [Abstract] [Full Text] [PDF]  

PHYSICAL SCIENCES

Applied Mathematics

David Porter, Stephen Rassenti, Anil Roopnarine, and Vernon Smith

Combinatorial auction design
PNAS 2003 100: 11153-11157; published online before print July 31 2003, 10.1073/pnas.1633736100 [Abstract] [Full Text] [PDF]  
See Commentary on page 10590

Applied Physical Sciences

Eduard Arzt, Stanislav Gorb, and Ralph Spolenak

From micro to nano contacts in biological attachment devices
PNAS 2003 100: 10603-10606; published online before print September 5 2003, 10.1073/pnas.1534701100 [Abstract] [Full Text] [PDF]  

Jamie R. Link and Michael J. Sailor

Smart dust: Self-assembling, self-orienting photonic crystals of porous Si
PNAS 2003 100: 10607-10610; published online before print August 28 2003, 10.1073/pnas.1233824100 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Chemistry

John W. Daly, H. Martin Garraffo, Thomas F. Spande, Valerie C. Clark, Jingyuan Ma, Herman Ziffer, and John F. Cover, Jr.

Evidence for an enantioselective pumiliotoxin 7-hydroxylase in dendrobatid poison frogs of the genus Dendrobates
PNAS 2003 100: 11092-11097; published online before print September 5 2003, 10.1073/pnas.1834430100 [Abstract] [Full Text] [PDF] [Supporting Text]  

SOCIAL SCIENCES

Economic Sciences

David Porter, Stephen Rassenti, Anil Roopnarine, and Vernon Smith

Combinatorial auction design
PNAS 2003 100: 11153-11157; published online before print July 31 2003, 10.1073/pnas.1633736100 [Abstract] [Full Text] [PDF]  
See Commentary on page 10590

Ronald W. Jones Inaugural Article by a Recently Elected Academy Member: Inaugural Article: Globalization and the distribution of income: The economic arguments PNAS 2003 100: 11158-11162; published online before print September 5 2003, 10.1073/pnas.1733335100 [Abstract] [Full Text] [PDF]

Psychology

Melissa A. Rosenkranz, Daren C. Jackson, Kim M. Dalton, Isa Dolski, Carol D. Ryff, Burt H. Singer, Daniel Muller, Ned H. Kalin, and Richard J. Davidson

Affective style and in vivo immune response: Neurobehavioral mechanisms
PNAS 2003 100: 11148-11152; published online before print September 5 2003, 10.1073/pnas.1534743100 [Abstract] [Full Text] [PDF]  

Richard E. Nisbett and Takahiko Masuda

Inaugural Articles: Culture and point of view
PNAS 2003 100: 11163-11170; published online before print September 5 2003, 10.1073/pnas.1934527100 [Abstract] [Full Text] [PDF]  

James K. Nelson, Patricia A. Reuter-Lorenz, Ching-Yune C. Sylvester, John Jonides, and Edward E. Smith

Dissociable neural mechanisms underlying response-based and familiarity-based conflict in working memory
PNAS 2003 100: 11171-11175; published online before print September 4 2003, 10.1073/pnas.1334125100 [Abstract] [Full Text] [PDF]  

Social Sciences

BIOLOGICAL SCIENCES

Applied Biological Sciences

J. Andrew Aquilina, Justin L. P. Benesch, Orval A. Bateman, Christine Slingsby, and Carol V. Robinson

Polydispersity of a mammalian chaperone: Mass spectrometry reveals the population of oligomers in B-crystallin
PNAS 2003 100: 10611-10616; published online before print August 28 2003, 10.1073/pnas.1932958100 [Abstract] [Full Text] [PDF]  

Biochemistry

Jen-Tsan Chi, Howard Y. Chang, Guttorm Haraldsen, Frode L. Jahnsen, Olga G. Troyanskaya, Dustin S. Chang, Zhen Wang, Stanley G. Rockson, Matt van de Rijn, David Botstein, and Patrick O. Brown

Endothelial cell diversity revealed by global expression profiling
PNAS 2003 100: 10623-10628; published online before print September 8 2003, 10.1073/pnas.1434429100 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Scott Classen, Stephane Olland, and James M. Berger

Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187
PNAS 2003 100: 10629-10634; published online before print September 8 2003, 10.1073/pnas.1832879100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Yutong Xue, Richard Gibbons, Zhijiang Yan, Dafeng Yang, Tarra L. McDowell, Salvatore Sechi, Jun Qin, Sharleen Zhou, Doug Higgs, and Weidong Wang

The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies
PNAS 2003 100: 10635-10640; published online before print September 2 2003, 10.1073/pnas.1937626100 [Abstract] [Full Text] [PDF]  

Man-Ho Cho, Syed G. A. Moinuddin, Gregory L. Helms, Shojiro Hishiyama, Dietmar Eichinger, Laurence B. Davin, and Norman G. Lewis

(+)-Larreatricin hydroxylase, an enantio-specific polyphenol oxidase from the creosote bush (Larrea tridentata)
PNAS 2003 100: 10641-10646; published online before print September 5 2003, 10.1073/pnas.1934562100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Christopher M. Adams, Joseph L. Goldstein, and Michael S. Brown

Cholesterol-induced conformational change in SCAP enhanced by Insig proteins and mimicked by cationic amphiphiles
PNAS 2003 100: 10647-10652; published online before print September 8 2003, 10.1073/pnas.1534833100 [Abstract] [Full Text] [PDF] [Supporting Text]  

Srigiridhar Kotamraju, Yoshiko Tampo, Agnes Keszler, Christopher R. Chitambar, Joy Joseph, Arthur L. Haas, and B. Kalyanaraman

Nitric oxide inhibits H₂O₂-induced transferrin receptor-dependent apoptosis in endothelial cells: Role of ubiquitin-proteasome pathway
PNAS 2003 100: 10653-10658; published online before print September 4 2003, 10.1073/pnas.1933581100 [Abstract] [Full Text] [PDF]  

Juan E. Ugalde, Armando J. Parodi, and Rodolfo A. Ugalde

De novo synthesis of bacterial glycogen: Agrobacterium tumefaciens glycogen synthase is involved in glucan initiation and elongation
PNAS 2003 100: 10659-10663; published online before print September 5 2003, 10.1073/pnas.1534787100 [Abstract] [Full Text] [PDF]  

Junsuke Igarashi, Phillip A. Erwin, Ana Paula V. Dantas, Hongjie Chen, and Thomas Michel

VEGF induces S1P₁ receptors in endothelial cells: Implications for cross-talk between sphingolipid and growth factor receptors
PNAS 2003 100: 10664-10669; published online before print September 8 2003, 10.1073/pnas.1934494100 [Abstract] [Full Text] [PDF]  

Bartosz Szczesny, Tapas K. Hazra, John Papaconstantinou, Sankar Mitra, and Istvan Boldogh

Age-dependent deficiency in import of mitochondrial DNA glycosylases required for repair of oxidatively damaged bases
PNAS 2003 100: 10670-10675; published online before print September 5 2003, 10.1073/pnas.1932854100 [Abstract] [Full Text] [PDF]  

Bijay S. Jaiswal and Marco Conti

Calcium regulation of the soluble adenylyl cyclase expressed in mammalian spermatozoa
PNAS 2003 100: 10676-10681; published online before print September 4 2003, 10.1073/pnas.1831008100 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Kisaburo Nagamune, Kazuhito Ohishi, Hisashi Ashida, Yeonchul Hong, Jun Hino, Kenji Kangawa, Norimitsu Inoue, Yusuke Maeda, and Taroh Kinoshita

GPI transamidase of Trypanosoma brucei has two previously uncharacterized (trypanosomatid transamidase 1 and 2) and three common subunits
PNAS 2003 100: 10682-10687; published online before print September 4 2003, 10.1073/pnas.1833260100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Nathalie Cadieux, Phu G. Phan, David S. Cafiso, and Robert J. Kadner

Differential substrate-induced signaling through the TonB-dependent transporter BtuB
PNAS 2003 100: 10688-10693; published online before print September 4 2003, 10.1073/pnas.1932538100 [Abstract] [Full Text] [PDF]  

Adiel Cohen, Yaniv Nevo, and Nathan Nelson

The first external loop of the metal ion transporter DCT1 is involved in metal ion binding and specificity
PNAS 2003 100: 10694-10699; published online before print September 3 2003, 10.1073/pnas.1934572100 [Abstract] [Full Text] [PDF]  

Biophysics

Boris Fain and Michael Levitt

Funnel sculpting for in silico assembly of secondary structure elements of proteins
PNAS 2003 100: 10700-10705; published online before print August 18 2003, 10.1073/pnas.1732312100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Sorin Luca, Jim F. White, Awinder K. Sohal, Dmitri V. Filippov, Jacques H. van Boom, Reinhard Grisshammer, and Marc Baldus

The conformation of neurotensin bound to its G protein-coupled receptor
PNAS 2003 100: 10706-10711; published online before print September 5 2003, 10.1073/pnas.1834523100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Scott Brown, Nicolas J. Fawzi, and Teresa Head-Gordon

Coarse-grained sequences for protein folding and design
PNAS 2003 100: 10712-10717; published online before print September 8 2003, 10.1073/pnas.1931882100 [Abstract] [Full Text] [PDF]  

Sophie Pautot, Barbara J. Frisken, and D. A. Weitz

Engineering asymmetric vesicles
PNAS 2003 100: 10718-10721; published online before print September 8 2003, 10.1073/pnas.1931005100 [Abstract] [Full Text] [PDF]  

Gentaro Taga, Kayo Asakawa, Atsushi Maki, Yukuo Konishi, and Hideaki Koizumi

Brain imaging in awake infants by near-infrared optical topography
PNAS 2003 100: 10722-10727; published online before print September 5 2003, 10.1073/pnas.1932552100 [Abstract] [Full Text] [PDF]  

Catherine C. Park, Rhonda L. Henshall-Powell, Anna C. Erickson, Rabih Talhouk, Bahram Parvin, Mina J. Bissell, and Mary Helen Barcellos-Hoff

Ionizing radiation induces heritable disruption of epithelial cell interactions
PNAS 2003 100: 10728-10733; published online before print September 5 2003, 10.1073/pnas.1832185100 [Abstract] [Full Text] [PDF]  

Ilya Shmulevich, Harri Lähdesmäki, Edward R. Dougherty, Jaakko Astola, and Wei Zhang

The role of certain Post classes in Boolean network models of genetic networks
PNAS 2003 100: 10734-10739; published online before print September 8 2003, 10.1073/pnas.1534782100 [Abstract] [Full Text] [PDF]  

Cell Biology

M. Okigaki, C. Davis, M. Falasca, S. Harroch, D. P. Felsenfeld, M. P. Sheetz, and J. Schlessinger

Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration
PNAS 2003 100: 10740-10745; published online before print September 5 2003, 10.1073/pnas.1834348100 [Abstract] [Full Text] [PDF] [Supporting Text]  

Kiran N. Mahajan and Beverly S. Mitchell

Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase
PNAS 2003 100: 10746-10751; published online before print September 5 2003, 10.1073/pnas.1631060100 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Sharon Wald Krauss, Cynthia Chen, Sheldon Penman, and Rebecca Heald

Nuclear actin and protein 4.1: Essential interactions during nuclear assembly in vitro
PNAS 2003 100: 10752-10757; published online before print September 5 2003, 10.1073/pnas.1934680100 [Abstract] [Full Text] [PDF]  

Esben A. Nilssen, Marianne Synnes, Nancy Kleckner, Beáta Grallert, and Erik Boye

Intra-G₁ arrest in response to UV irradiation in fission yeast
PNAS 2003 100: 10758-10763; published online before print September 5 2003, 10.1073/pnas.1833769100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Tau-Mu Yi, Hiroaki Kitano, and Melvin I. Simon

A quantitative characterization of the yeast heterotrimeric G protein cycle
PNAS 2003 100: 10764-10769; published online before print September 5 2003, 10.1073/pnas.1834247100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Sunita K. Agarwal, Elizabeth A. Novotny, Judy S. Crabtree, Jonathan B. Weitzman, Moshe Yaniv, A. Lee Burns, Settara C. Chandrasekharappa, Francis S. Collins, Allen M. Spiegel, and Stephen J. Marx

Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter
PNAS 2003 100: 10770-10775; published online before print September 5 2003, 10.1073/pnas.1834524100 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Yang Xiang and Brian Kobilka

The PDZ-binding motif of the ₂-adrenoceptor is essential for physiologic signaling and trafficking in cardiac myocytes
PNAS 2003 100: 10776-10781; published online before print September 3 2003, 10.1073/pnas.1831718100 [Abstract] [Full Text] [PDF]  

Huijun Wei, Seungkirl Ahn, Sudha K. Shenoy, Sadashiva S. Karnik, László Hunyady, Louis M. Luttrell, and Robert J. Lefkowitz

Independent -arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
PNAS 2003 100: 10782-10787; published online before print August 29 2003, 10.1073/pnas.1834556100 [Abstract] [Full Text] [PDF]  

T. Omelchenko, J. M. Vasiliev, I. M. Gelfand, H. H. Feder, and E. M. Bonder

Rho-dependent formation of epithelial "leader" cells during wound healing
PNAS 2003 100: 10788-10793; published online before print September 5 2003, 10.1073/pnas.1834401100 [Abstract] [Full Text] [PDF]  

Developmental Biology

Hwei-Ling Cheng, Raul Mostoslavsky, Shin'ichi Saito, John P. Manis, Yansong Gu, Parin Patel, Roderick Bronson, Ettore Appella, Frederick W. Alt, and Katrin F. Chua

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
PNAS 2003 100: 10794-10799; published online before print September 5 2003, 10.1073/pnas.1934713100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Ecology

David A. Burney, Guy S. Robinson, and Lida Pigott Burney

Sporormiella and the late Holocene extinctions in Madagascar
PNAS 2003 100: 10800-10805; published online before print September 5 2003, 10.1073/pnas.1534700100 [Abstract] [Full Text] [PDF]  

Evolution

Eduard Arzt, Stanislav Gorb, and Ralph Spolenak

From micro to nano contacts in biological attachment devices
PNAS 2003 100: 10603-10606; published online before print September 5 2003, 10.1073/pnas.1534701100 [Abstract] [Full Text] [PDF]  

Camilla L. Nesbø and W. Ford Doolittle

Active self-splicing group I introns in 23S rRNA genes of hyperthermophilic bacteria, derived from introns in eukaryotic organelles
PNAS 2003 100: 10806-10811; published online before print August 28 2003, 10.1073/pnas.1434268100 [Abstract] [Full Text] [PDF]  

Peter L. Morrell, Karen E. Lundy, and Michael T. Clegg

Distinct geographic patterns of genetic diversity are maintained in wild barley (Hordeum vulgare ssp. spontaneum) despite migration
PNAS 2003 100: 10812-10817; published online before print September 8 2003, 10.1073/pnas.1633708100 [Abstract] [Full Text] [PDF] [Supporting Information]  

N. J. Besansky, J. Krzywinski, T. Lehmann, F. Simard, M. Kern, O. Mukabayire, D. Fontenille, Y. Touré, and N'F. Sagnon

Semipermeable species boundaries between Anopheles gambiae and Anopheles arabiensis: Evidence from multilocus DNA sequence variation
PNAS 2003 100: 10818-10823; published online before print August 28 2003, 10.1073/pnas.1434337100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Hyosig Won and Susanne S. Renner

Horizontal gene transfer from flowering plants to Gnetum
PNAS 2003 100: 10824-10829; published online before print September 8 2003, 10.1073/pnas.1833775100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Ester Lázaro, Cristina Escarmís, Juan Pérez-Mercader, Susanna C. Manrubia, and Esteban Domingo

Resistance of virus to extinction on bottleneck passages: Study of a decaying and fluctuating pattern of fitness loss
PNAS 2003 100: 10830-10835; published online before print September 5 2003, 10.1073/pnas.1332668100 [Abstract] [Full Text] [PDF]  

Eduard D. Akhunov, Alina R. Akhunova, Anna M. Linkiewicz, Jorge Dubcovsky, David Hummel, Gerard R. Lazo, Shiaoman Chao, Olin D. Anderson, Jacques David, Lili Qi, Benjamin Echalier, Bikram S. Gill, Miftahudin, J. Perry Gustafson, Mauricio La Rota, Mark E. Sorrells, Deshui Zhang, Henry T. Nguyen, Venugopal Kalavacharla, Khwaja Hossain, Shahryar F. Kianian, Junhua Peng, Nora L. V. Lapitan, Emily J. Wennerlind, Vivienne Nduati, James A. Anderson, Deepak Sidhu, Kulvinder S. Gill, Patrick E. McGuire, Calvin O. Qualset, and Jan Dvorak

Synteny perturbations between wheat homoeologous chromosomes caused by locus duplications and deletions correlate with recombination rates
PNAS 2003 100: 10836-10841; published online before print September 5 2003, 10.1073/pnas.1934431100 [Abstract] [Full Text] [PDF] [Supporting Tables]  

Genetics

Fumiaki Katagiri and Jane Glazebrook

Local Context Finder (LCF) reveals multidimensional relationships among mRNA expression profiles of Arabidopsis responding to pathogen infection
PNAS 2003 100: 10842-10847; published online before print September 5 2003, 10.1073/pnas.1934349100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Timothy C. Hallstrom and Joseph R. Nevins

Specificity in the activation and control of transcription factor E2F-dependent apoptosis
PNAS 2003 100: 10848-10853; published online before print September 3 2003, 10.1073/pnas.1831408100 [Abstract] [Full Text] [PDF]  

Piotr A. Mieczkowski, Joanna O. Mieczkowska, Margaret Dominska, and Thomas D. Petes

Genetic regulation of telomere-telomere fusions in the yeast Saccharomyces cerevisae
PNAS 2003 100: 10854-10859; published online before print September 8 2003, 10.1073/pnas.1934561100 [Abstract] [Full Text] [PDF] [Supporting Information]  

R. Grace Zhai, P. Robin Hiesinger, Tong-Wey Koh, Patrik Verstreken, Karen L. Schulze, Yu Cao, Hamed Jafar-Nejad, Koenraad K. Norga, Hongling Pan, Vafa Bayat, Michael P. Greenbaum, and Hugo J. Bellen

Mapping Drosophila mutations with molecularly defined P element insertions
PNAS 2003 100: 10860-10865; published online before print September 5 2003, 10.1073/pnas.1832753100 [Abstract] [Full Text] [PDF] [Supporting Table]  

Brian K. Jordan, Jennifer H.-C. Shen, Robert Olaso, Holly A. Ingraham, and Eric Vilain

Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/-catenin synergy
PNAS 2003 100: 10866-10871; published online before print August 29 2003, 10.1073/pnas.1834480100 [Abstract] [Full Text] [PDF]  

Immunology

Kenya Honda, Shinya Sakaguchi, Chigusa Nakajima, Ai Watanabe, Hideyuki Yanai, Misako Matsumoto, Toshiaki Ohteki, Tsuneyasu Kaisho, Akinori Takaoka, Shizuo Akira, Tsukasa Seya, and Tadatsugu Taniguchi

Selective contribution of IFN-/ signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection
PNAS 2003 100: 10872-10877; published online before print September 5 2003, 10.1073/pnas.1934678100 [Abstract] [Full Text] [PDF] [Supporting Figures]  

E. Allison Green, Leonid Gorelik, Catrin M. McGregor, Elise H. Tran, and Richard A. Flavell

CD4⁺CD25⁺ T regulatory cells control anti-islet CD8⁺ T cells through TGF-–TGF- receptor interactions in type 1 diabetes
PNAS 2003 100: 10878-10883; published online before print August 29 2003, 10.1073/pnas.1834400100 [Abstract] [Full Text] [PDF]  

D. M. Belnap, N. R. Watts, J. F. Conway, N. Cheng, S. J. Stahl, P. T. Wingfield, and A. C. Steven

Diversity of core antigen epitopes of hepatitis B virus
PNAS 2003 100: 10884-10889; published online before print September 3 2003, 10.1073/pnas.1834404100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Santanu Bose, Niladri Kar, Ratan Maitra, Joseph A. DiDonato, and Amiya K. Banerjee

Temporal activation of NF-B regulates an interferon-independent innate antiviral response against cytoplasmic RNA viruses
PNAS 2003 100: 10890-10895; published online before print September 5 2003, 10.1073/pnas.1832775100 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Gabriella Pietra, Chiara Romagnani, Paola Mazzarino, Michela Falco, Enrico Millo, Alessandro Moretta, Lorenzo Moretta, and Maria Cristina Mingari

HLA-E-restricted recognition of cytomegalovirus-derived peptides by human CD8⁺ cytolytic T lymphocytes
PNAS 2003 100: 10896-10901; published online before print September 5 2003, 10.1073/pnas.1834449100 [Abstract] [Full Text] [PDF]  

Hiroyoshi Nishikawa, Takuma Kato, Koji Tanida, Atsunori Hiasa, Isao Tawara, Hiroaki Ikeda, Yoshinori Ikarashi, Hiro Wakasugi, Mitchell Kronenberg, Toshinori Nakayama, Masaru Taniguchi, Kagemasa Kuribayashi, Lloyd J. Old, and Hiroshi Shiku

CD4⁺ CD25⁺ T cells responding to serologically defined autoantigens suppress antitumor immune responses
PNAS 2003 100: 10902-10906; published online before print August 28 2003, 10.1073/pnas.1834479100 [Abstract] [Full Text] [PDF]  

Hugh Rosen, Christopher Alfonso, Charles D. Surh, and Michael G. McHeyzer-Williams

Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist
PNAS 2003 100: 10907-10912; published online before print September 3 2003, 10.1073/pnas.1832725100 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Michael T. Wilson, Cecilia Johansson, Danyvid Olivares-Villagómez, Avneesh K. Singh, Aleksandar K. Stanic, Chyung-Ru Wang, Sebastian Joyce, Mary Jo Wick, and Luc Van Kaer

The response of natural killer T cells to glycolipid antigens is characterized by surface receptor down-modulation and expansion
PNAS 2003 100: 10913-10918; published online before print September 5 2003, 10.1073/pnas.1833166100 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Daisuke Ishida, Hailin Yang, Kyoko Masuda, Kanami Uesugi, Hiroshi Kawamoto, Masakazu Hattori, and Nagahiro Minato

Antigen-driven T cell anergy and defective memory T cell response via deregulated Rap1 activation in SPA-1-deficient mice
PNAS 2003 100: 10919-10924; published online before print September 4 2003, 10.1073/pnas.1834525100 [Abstract] [Full Text] [PDF]  

Gi-Eun Rhie, Michael H. Roehrl, Michael Mourez, R. John Collier, John J. Mekalanos, and Julia Y. Wang

A dually active anthrax vaccine that confers protection against both bacilli and toxins
PNAS 2003 100: 10925-10930; published online before print September 5 2003, 10.1073/pnas.1834478100 [Abstract] [Full Text] [PDF]  

Medical Sciences

Scott Classen, Stephane Olland, and James M. Berger

Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187
PNAS 2003 100: 10629-10634; published online before print September 8 2003, 10.1073/pnas.1832879100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Dale Porter, Stanislawa Weremowicz, Koei Chin, Pankaj Seth, Aparna Keshaviah, Jaana Lahti-Domenici, Young Kyung Bae, Constance L. Monitto, Ana Merlos-Suarez, Jennifer Chan, Christine M. Hulette, Andrea Richardson, Cynthia C. Morton, Jeffrey Marks, Mabel Duyao, Ralph Hruban, Edward Gabrielson, Rebecca Gelman, and Kornelia Polyak

A neural survival factor is a candidate oncogene in breast cancer
PNAS 2003 100: 10931-10936; published online before print September 2 2003, 10.1073/pnas.1932980100 [Abstract] [Full Text] [PDF]  

Stefano Fiorucci, Luca Santucci, John L. Wallace, Marco Sardina, Mario Romano, Piero del Soldato, and Antonio Morelli

Interaction of a selective cyclooxygenase-2 inhibitor with aspirin and NO-releasing aspirin in the human gastric mucosa
PNAS 2003 100: 10937-10941; published online before print September 5 2003, 10.1073/pnas.1933204100 [Abstract] [Full Text] [PDF]  

Ekaterina Dadachova, Antonio Nakouzi, Ruth A. Bryan, and Arturo Casadevall

Ionizing radiation delivered by specific antibody is therapeutic against a fungal infection
PNAS 2003 100: 10942-10947; published online before print August 20 2003, 10.1073/pnas.1731272100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Scott D. Kobayashi, Kevin R. Braughton, Adeline R. Whitney, Jovanka M. Voyich, Tom G. Schwan, James M. Musser, and Frank R. DeLeo From the Cover: Bacterial pathogens modulate an apoptosis differentiation program in human neutrophils PNAS 2003 100: 10948-10953; published online before print September 5 2003, 10.1073/pnas.1833375100 [Abstract] [Full Text] [PDF] [Supporting Information]

Juan Juan Yin, Khalid S. Mohammad, Sanna M. Käkönen, Stephen Harris, J. Ruth Wu-Wong, Jerry L. Wessale, Robert J. Padley, I. Ross Garrett, John M. Chirgwin, and Theresa A. Guise From the Cover: A causal role for endothelin-1 in the pathogenesis of osteoblastic bone metastases PNAS 2003 100: 10954-10959; published online before print August 26 2003, 10.1073/pnas.1830978100 [Abstract] [Full Text] [PDF]   See Commentary on page 10588

Mike B. Gravenor, Nigel Stallard, Robert Curnow, and Angela R. McLean

Repeated challenge with prion disease: The risk of infection and impact on incubation period
PNAS 2003 100: 10960-10965; published online before print September 5 2003, 10.1073/pnas.1833677100 [Abstract] [Full Text] [PDF]  

Faith M. Harris, Walter J. Brecht, Qin Xu, Ina Tesseur, Lisa Kekonius, Tony Wyss-Coray, Jo Dee Fish, Eliezer Masliah, Paul C. Hopkins, Kimberly Scearce-Levie, Karl H. Weisgraber, Lennart Mucke, Robert W. Mahley, and Yadong Huang

Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice
PNAS 2003 100: 10966-10971; published online before print August 25 2003, 10.1073/pnas.1434398100 [Abstract] [Full Text] [PDF]  

Nicolas de Roux, Emmanuelle Genin, Jean-Claude Carel, Fumihiko Matsuda, Jean-Louis Chaussain, and Edwin Milgrom

Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54
PNAS 2003 100: 10972-10976; published online before print August 27 2003, 10.1073/pnas.1834399100 [Abstract] [Full Text] [PDF]  

Janet M. Harouse, Clarisa Buckner, Agegnehu Gettie, Ross Fuller, Rudolf Bohm, James Blanchard, and Cecilia Cheng-Mayer

CD8⁺ T cell-mediated CXC chemokine receptor 4-simian/human immunodeficiency virus suppression in dually infected rhesus macaques
PNAS 2003 100: 10977-10982; published online before print September 8 2003, 10.1073/pnas.1933268100 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Microbiology

Chad W. Saltikov and Dianne K. Newman

Genetic identification of a respiratory arsenate reductase
PNAS 2003 100: 10983-10988; published online before print August 25 2003, 10.1073/pnas.1834303100 [Abstract] [Full Text] [PDF]  

Sibille Humme, Gilbert Reisbach, Regina Feederle, Henri-Jacques Delecluse, Kristine Bousset, Wolfgang Hammerschmidt, and Aloys Schepers

The EBV nuclear antigen 1 (EBNA1) enhances B cell immortalization several thousandfold
PNAS 2003 100: 10989-10994; published online before print August 28 2003, 10.1073/pnas.1832776100 [Abstract] [Full Text] [PDF]  

J. Maxwell Dow, Lisa Crossman, Kim Findlay, Yong-Qiang He, Jia-Xun Feng, and Ji-Liang Tang

Biofilm dispersal in Xanthomonas campestris is controlled by cell–cell signaling and is required for full virulence to plants
PNAS 2003 100: 10995-11000; published online before print September 5 2003, 10.1073/pnas.1833360100 [Abstract] [Full Text] [PDF]  

Xiaofeng F. Yang, Sophie M. Alani, and Michael V. Norgard

The response regulator Rrp2 is essential for the expression of major membrane lipoproteins in Borrelia burgdorferi
PNAS 2003 100: 11001-11006; published online before print August 29 2003, 10.1073/pnas.1834315100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Ifat Rubin-Bejerano, Iain Fraser, Paula Grisafi, and Gerald R. Fink

Phagocytosis by neutrophils induces an amino acid deprivation response in Saccharomyces cerevisiae and Candida albicans
PNAS 2003 100: 11007-11012; published online before print September 4 2003, 10.1073/pnas.1834481100 [Abstract] [Full Text] [PDF]  

Pin-Fang Lin, Wade Blair, Tao Wang, Timothy Spicer, Qi Guo, Nannan Zhou, Yi-Fei Gong, H.-G. Heidi Wang, Ronald Rose, Gregory Yamanaka, Brett Robinson, Chang-Ben Li, Robert Fridell, Carol Deminie, Gwendeline Demers, Zheng Yang, Lisa Zadjura, Nicholas Meanwell, and Richard Colonno From the Cover: A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor binding PNAS 2003 100: 11013-11018; published online before print August 20 2003, 10.1073/pnas.1832214100 [Abstract] [Full Text] [PDF] [Supporting Table]   See Commentary on page 10581

Neuroscience

J. Garey, A. Goodwillie, J. Frohlich, M. Morgan, J.-A. Gustafsson, O. Smithies, K. S. Korach, S. Ogawa, and D. W. Pfaff

Genetic contributions to generalized arousal of brain and behavior
PNAS 2003 100: 11019-11022; published online before print August 20 2003, 10.1073/pnas.1633773100 [Abstract] [Full Text] [PDF]  

Schuichi Koizumi, Kayoko Fujishita, Makoto Tsuda, Yukari Shigemoto-Mogami, and Kazuhide Inoue

Dynamic inhibition of excitatory synaptic transmission by astrocyte-derived ATP in hippocampal cultures
PNAS 2003 100: 11023-11028; published online before print September 4 2003, 10.1073/pnas.1834448100 [Abstract] [Full Text] [PDF]  

Fuqiang Xu, Nian Liu, Ikuhiro Kida, Douglas L. Rothman, Fahmeed Hyder, and Gordon M. Shepherd

Odor maps of aldehydes and esters revealed by functional MRI in the glomerular layer of the mouse olfactory bulb
PNAS 2003 100: 11029-11034; published online before print September 8 2003, 10.1073/pnas.1832864100 [Abstract] [Full Text] [PDF]  

Michel Cyr, Jean-Martin Beaulieu, Aki Laakso, Tatyana D. Sotnikova, Wei-Dong Yao, Laura M. Bohn, Raul R. Gainetdinov, and Marc G. Caron

Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons
PNAS 2003 100: 11035-11040; published online before print September 4 2003, 10.1073/pnas.1831768100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Miguel A. L. Nicolelis, Dragan Dimitrov, Jose M. Carmena, Roy Crist, Gary Lehew, Jerald D. Kralik, and Steven P. Wise

Chronic, multisite, multielectrode recordings in macaque monkeys
PNAS 2003 100: 11041-11046; published online before print September 5 2003, 10.1073/pnas.1934665100 [Abstract] [Full Text] [PDF] [Supporting Information]  

R. D. Traub, M. O. Cunningham, T. Gloveli, F. E. N. LeBeau, A. Bibbig, E. H. Buhl, and M. A. Whittington

GABA-enhanced collective behavior in neuronal axons underlies persistent gamma-frequency oscillations
PNAS 2003 100: 11047-11052; published online before print September 5 2003, 10.1073/pnas.1934854100 [Abstract] [Full Text] [PDF]  

H. Laufs, K. Krakow, P. Sterzer, E. Eger, A. Beyerle, A. Salek-Haddadi, and A. Kleinschmidt

Electroencephalographic signatures of attentional and cognitive default modes in spontaneous brain activity fluctuations at rest
PNAS 2003 100: 11053-11058; published online before print September 4 2003, 10.1073/pnas.1831638100 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Craig S. Clements, Hugh H. Reid, Travis Beddoe, Fleur E. Tynan, Matthew A. Perugini, Terrance G. Johns, Claude C. A. Bernard, and Jamie Rossjohn

The crystal structure of myelin oligodendrocyte glycoprotein, a key autoantigen in multiple sclerosis
PNAS 2003 100: 11059-11064; published online before print September 5 2003, 10.1073/pnas.1833158100 [Abstract] [Full Text] [PDF]  

D. Larry Sparks and Bernard G. Schreurs

Trace amounts of copper in water induce -amyloid plaques and learning deficits in a rabbit model of Alzheimer's disease
PNAS 2003 100: 11065-11069; published online before print August 14 2003, 10.1073/pnas.1832769100 [Abstract] [Full Text] [PDF]  

Ralph E. Beitel, Christoph E. Schreiner, Steven W. Cheung, Xiaoqin Wang, and Michael M. Merzenich

Reward-dependent plasticity in the primary auditory cortex of adult monkeys trained to discriminate temporally modulated signals
PNAS 2003 100: 11070-11075; published online before print August 26 2003, 10.1073/pnas.1334187100 [Abstract] [Full Text] [PDF]  

Thomas A. Christensen, Hong Lei, and John G. Hildebrand

Coordination of central odor representations through transient, non-oscillatory synchronization of glomerular output neurons
PNAS 2003 100: 11076-11081; published online before print September 5 2003, 10.1073/pnas.1934001100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Hermann Cuntz, Jürgen Haag, and Alexander Borst

Neural image processing by dendritic networks
PNAS 2003 100: 11082-11085; published online before print August 28 2003, 10.1073/pnas.1830705100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Pharmacology

Florence Gbahou, Agnès Rouleau, Séverine Morisset, Régis Parmentier, Sylvain Crochet, Jian-Sheng Lin, Xavier Ligneau, Joël Tardivel-Lacombe, Holger Stark, Walter Schunack, C. Robin Ganellin, Jean-Charles Schwartz, and Jean-Michel Arrang

Protean agonism at histamine H₃ receptors in vitro and in vivo
PNAS 2003 100: 11086-11091; published online before print September 5 2003, 10.1073/pnas.1932276100 [Abstract] [Full Text] [PDF]  

John W. Daly, H. Martin Garraffo