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Table of Contents

January 21, 2003; 100 (2)  [Index By Author]  [Cover Photo]

FROM THE COVER

Nondiffusive protein uptake in ion exchange particles

Tools for DNA sequencing by synthesis (A)

Tools for DNA sequencing by synthesis (B)

How palytoxin opens gates

Community diversity decreases Lyme disease risk

Identifying disease genes with integrative genomics

COMMENTARIES

PHYSICAL SCIENCES
    Applied Physical Sciences
    Chemistry
    Engineering
    Mathematics

SOCIAL SCIENCES

BIOLOGICAL SCIENCES
    Applied Biological Sciences
    Biochemistry
    Biophysics
    Cell Biology
    Developmental Biology
    Ecology
    Evolution
    Genetics

    Immunology
    Medical Sciences
    Microbiology
    Neuroscience
    Pharmacology
    Physiology
    Plant Biology

CORRECTIONS

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COMMENTARIES

Lynmarie K. Thompson
Unraveling the secrets of Alzheimer's beta -amyloid fibrils
PNAS 2003 100: 383-385; published online before print January 13 2003, 10.1073/pnas.0337745100 [Extract] [Full Text] [PDF]  
See companion article on page 16742 in issue 26 of volume 99

Donald W. Hilgemann
From a pump to a pore: How palytoxin opens the gates
PNAS 2003 100: 386-388; published online before print January 13 2003, 10.1073/pnas.0437775100 [Extract] [Full Text] [PDF]  
See companion article on page 501

PHYSICAL SCIENCES

Applied Physical Sciences

Matthew J. Dejneka, Alexander Streltsov, Santona Pal, Anthony G. Frutos, Christy L. Powell, Kevin Yost, Po Ki Yuen, Uwe Müller, and Joydeep Lahiri
Rare earth-doped glass microbarcodes
PNAS 2003 100: 389-393; published online before print January 6 2003, 10.1073/pnas.0236044100 [Abstract] [Full Text] [PDF]  

Chemistry

Emanuele Paci, Jane Clarke, Annette Steward, Michele Vendruscolo, and Martin Karplus
Self-consistent determination of the transition state for protein folding: Application to a fibronectin type III domain
PNAS 2003 100: 394-399; published online before print January 6 2003, 10.1073/pnas.232704999 [Abstract] [Full Text] [PDF]  

Ann-Sofie Cans, Nathan Wittenberg, Roger Karlsson, Leslie Sombers, Mattias Karlsson, Owe Orwar, and Andrew Ewing
Artificial cells: Unique insights into exocytosis using liposomes and lipid nanotubes
PNAS 2003 100: 400-404; published online before print January 3 2003, 10.1073/pnas.232702599 [Abstract] [Full Text] [PDF]  

Inhee Chung, Ken T. Shimizu, and Moungi G. Bawendi
Room temperature measurements of the 3D orientation of single CdSe quantum dots using polarization microscopy
PNAS 2003 100: 405-408; published online before print January 6 2003, 10.1073/pnas.0133507100 [Abstract] [Full Text] [PDF]  

Xiaopeng Bai, Zengmin Li, Steffen Jockusch, Nicholas J. Turro, and Jingyue Ju
From the Cover: Photocleavage of a 2-nitrobenzyl linker bridging a fluorophore to the 5' end of DNA
PNAS 2003 100: 409-413; published online before print January 6 2003, 10.1073/pnas.242729099 [Abstract] [Full Text] [PDF]  

Zengmin Li, Xiaopeng Bai, Hameer Ruparel, Sobin Kim, Nicholas J. Turro, and Jingyue Ju
A photocleavable fluorescent nucleotide for DNA sequencing and analysis
PNAS 2003 100: 414-419; published online before print January 6 2003, 10.1073/pnas.242729199 [Abstract] [Full Text] [PDF]  

Engineering

S. R. Dziennik, E. B. Belcher, G. A. Barker, M. J. DeBergalis, S. E. Fernandez, and A. M. Lenhoff
From the Cover: Nondiffusive mechanisms enhance protein uptake rates in ion exchange particles
PNAS 2003 100: 420-425; published online before print January 8 2003, 10.1073/pnas.0237084100 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Mathematics

Yael Karshon, Shlomo Sternberg, and Jonathan Weitsman
The Euler-Maclaurin formula for simple integral polytopes
PNAS 2003 100: 426-433; published online before print January 6 2003, 10.1073/pnas.0237168100 [Abstract] [Full Text] [PDF]  

Thomas J. Enright and Jeb F. Willenbring
Hilbert series, Howe duality, and branching rules
PNAS 2003 100: 434-437; published online before print January 13 2003, 10.1073/pnas.0136632100 [Abstract] [Full Text] [PDF]  

SOCIAL SCIENCES

BIOLOGICAL SCIENCES

Applied Biological Sciences

Stephen P. Mayfield, Scott E. Franklin, and Richard A. Lerner
Expression and assembly of a fully active antibody in algae
PNAS 2003 100: 438-442; published online before print January 8 2003, 10.1073/pnas.0237108100 [Abstract] [Full Text] [PDF]  

Arthur R. Salomon, Scott B. Ficarro, Laurence M. Brill, Achim Brinker, Qui T. Phung, Christer Ericson, Karsten Sauer, Ansgar Brock, David M. Horn, Peter G. Schultz, and Eric C. Peters
Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry
PNAS 2003 100: 443-448; published online before print January 9 2003, 10.1073/pnas.2436191100 [Abstract] [Full Text] [PDF]  

Biochemistry

Matthew J. Dejneka, Alexander Streltsov, Santona Pal, Anthony G. Frutos, Christy L. Powell, Kevin Yost, Po Ki Yuen, Uwe Müller, and Joydeep Lahiri
Rare earth-doped glass microbarcodes
PNAS 2003 100: 389-393; published online before print January 6 2003, 10.1073/pnas.0236044100 [Abstract] [Full Text] [PDF]  

Carla A. Theimer, L. David Finger, Lukas Trantirek, and Juli Feigon
Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA
PNAS 2003 100: 449-454; published online before print January 13 2003, 10.1073/pnas.242720799 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Jin Kuk Yang, Min S. Park, Geoffrey S. Waldo, and Se Won Suh
Directed evolution approach to a structural genomics project: Rv2002 from Mycobacterium tuberculosis
PNAS 2003 100: 455-460; published online before print January 10 2003, 10.1073/pnas.0137017100 [Abstract] [Full Text] [PDF] [Supporting Methods]  

Benjamin P. Luchsinger, Eric N. Rich, Andrew J. Gow, Elizabeth M. Williams, Jonathan S. Stamler, and David J. Singel
Routes to S-nitroso-hemoglobin formation with heme redox and preferential reactivity in the beta subunits
PNAS 2003 100: 461-466; published online before print January 10 2003, 10.1073/pnas.0233287100 [Abstract] [Full Text] [PDF]  

Chikashi Toyoshima, Michio Asahi, Yuji Sugita, Reena Khanna, Takeo Tsuda, and David H. MacLennan
Inaugural Article by a Recently Elected Academy Member:
Inaugural Article: Modeling of the inhibitory interaction of phospholamban with the Ca2+ ATPase
PNAS 2003 100: 467-472; published online before print January 13 2003, 10.1073/pnas.0237326100 [Abstract] [Full Text] [PDF]  

Hiroko Miyadera, Kazuro Shiomi, Hideaki Ui, Yuichi Yamaguchi, Rokuro Masuma, Hiroshi Tomoda, Hideto Miyoshi, Arihiro Osanai, Kiyoshi Kita, and Satoshi Omura
Atpenins, potent and specific inhibitors of mitochondrial complex II (succinate-ubiquinone oxidoreductase)
PNAS 2003 100: 473-477; published online before print January 6 2003, 10.1073/pnas.0237315100 [Abstract] [Full Text] [PDF]  

Haoyong Wang and Shaorong Chong
Visualization of coupled protein folding and binding in bacteria and purification of the heterodimeric complex
PNAS 2003 100: 478-483; published online before print January 6 2003, 10.1073/pnas.0236088100 [Abstract] [Full Text] [PDF]  

Janne Lehtiö, Junji Sugiyama, Malin Gustavsson, Linda Fransson, Markus Linder, and Tuula T. Teeri
The binding specificity and affinity determinants of family 1 and family 3 cellulose binding modules
PNAS 2003 100: 484-489; published online before print January 9 2003, 10.1073/pnas.212651999 [Abstract] [Full Text] [PDF]  

Anthony C. Bishop, Kirk Beebe, and Paul R. Schimmel
Interstice mutations that block site-to-site translocation of a misactivated amino acid bound to a class I tRNA synthetase
PNAS 2003 100: 490-494; published online before print January 6 2003, 10.1073/pnas.0237335100 [Abstract] [Full Text] [PDF]  

Biophysics

Xiaopeng Bai, Zengmin Li, Steffen Jockusch, Nicholas J. Turro, and Jingyue Ju
From the Cover: Photocleavage of a 2-nitrobenzyl linker bridging a fluorophore to the 5' end of DNA
PNAS 2003 100: 409-413; published online before print January 6 2003, 10.1073/pnas.242729099 [Abstract] [Full Text] [PDF]  

Zengmin Li, Xiaopeng Bai, Hameer Ruparel, Sobin Kim, Nicholas J. Turro, and Jingyue Ju
A photocleavable fluorescent nucleotide for DNA sequencing and analysis
PNAS 2003 100: 414-419; published online before print January 6 2003, 10.1073/pnas.242729199 [Abstract] [Full Text] [PDF]  

S. R. Dziennik, E. B. Belcher, G. A. Barker, M. J. DeBergalis, S. E. Fernandez, and A. M. Lenhoff
From the Cover: Nondiffusive mechanisms enhance protein uptake rates in ion exchange particles
PNAS 2003 100: 420-425; published online before print January 8 2003, 10.1073/pnas.0237084100 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Sanford H. Leuba, Mikhail A. Karymov, Miroslav Tomschik, Ravi Ramjit, Paul Smith, and Jordanka Zlatanova
Assembly of single chromatin fibers depends on the tension in the DNA molecule: Magnetic tweezers study
PNAS 2003 100: 495-500; published online before print January 9 2003, 10.1073/pnas.0136890100 [Abstract] [Full Text] [PDF]  

Pablo Artigas and David C. Gadsby
From the Cover: Na+/K+-pump ligands modulate gating of palytoxin-induced ion channels
PNAS 2003 100: 501-505; published online before print December 23 2002, 10.1073/pnas.0135849100 [Abstract] [Full Text] [PDF]  
See Commentary on page 386

J. W. Shuai and P. Jung
Optimal ion channel clustering for intracellular calcium signaling
PNAS 2003 100: 506-510; published online before print January 7 2003, 10.1073/pnas.0236032100 [Abstract] [Full Text] [PDF]  

Scott R. McKercher, Christian R. Lombardo, Andrey Bobkov, Xin Jia, and Nuria Assa-Munt
Identification of a PU.1-IRF4 protein interaction surface predicted by chemical exchange line broadening
PNAS 2003 100: 511-516; published online before print January 7 2003, 10.1073/pnas.0136910100 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Jonathan A. Lukin, Georg Kontaxis, Virgil Simplaceanu, Yue Yuan, Ad Bax, and Chien Ho
Quaternary structure of hemoglobin in solution
PNAS 2003 100: 517-520; published online before print January 13 2003, 10.1073/pnas.232715799 [Abstract] [Full Text] [PDF]  

Cell Biology

Julia Kirshner, Charng-Jui Chen, Pingfang Liu, Jie Huang, and John E. Shively
CEACAM1-4S, a cell-cell adhesion molecule, mediates apoptosis and reverts mammary carcinoma cells to a normal morphogenic phenotype in a 3D culture
PNAS 2003 100: 521-526; published online before print January 9 2003, 10.1073/pnas.232711199 [Abstract] [Full Text] [PDF] [Supporting Text]  

Guang-Zhi Li, Mark S. Eller, Reza Firoozabadi, and Barbara A. Gilchrest
Evidence that exposure of the telomere 3' overhang sequence induces senescence
PNAS 2003 100: 527-531; published online before print January 6 2003, 10.1073/pnas.0235444100 [Abstract] [Full Text] [PDF]  

Developmental Biology

Ting Luo, Young-Hoon Lee, Jean-Pierre Saint-Jeannet, and Thomas D. Sargent
Induction of neural crest in Xenopus by transcription factor AP2alpha
PNAS 2003 100: 532-537; published online before print January 2 2003, 10.1073/pnas.0237226100 [Abstract] [Full Text] [PDF]  

Frederick L. Moore, Jadwiga Jaruzelska, Mark S. Fox, Jun Urano, Meri T. Firpo, Paul J. Turek, David M. Dorfman, and Renee A. Reijo Pera
Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-Like proteins
PNAS 2003 100: 538-543; published online before print January 2 2003, 10.1073/pnas.0234478100 [Abstract] [Full Text] [PDF]  

Jinsong Zhu, Ken Miura, Li Chen, and Alexander S. Raikhel
Cyclicity of mosquito vitellogenic ecdysteroid-mediated signaling is modulated by alternative dimerization of the RXR homologue Ultraspiracle
PNAS 2003 100: 544-549; published online before print January 9 2003, 10.1073/pnas.0235695100 [Abstract] [Full Text] [PDF]  

Nobuhiro Suzumori, Kathleen H. Burns, Wei Yan, and Martin M. Matzuk
RFPL4 interacts with oocyte proteins of the ubiquitin-proteasome degradation pathway
PNAS 2003 100: 550-555; published online before print January 13 2003, 10.1073/pnas.0234474100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Clifford W. Bogue, Ping-Xia Zhang, James McGrath, Harris C. Jacobs, and Ramsay L. Fuleihan
Impaired B cell development and function in mice with a targeted disruption of the homeobox gene Hex
PNAS 2003 100: 556-561; published online before print January 8 2003, 10.1073/pnas.0236979100 [Abstract] [Full Text] [PDF]  

Ecology

William E. Williams, Holly L. Gorton, and Thomas C. Vogelmann
Surface gas-exchange processes of snow algae
PNAS 2003 100: 562-566; published online before print January 7 2003, 10.1073/pnas.0235560100 [Abstract] [Full Text] [PDF]  

Kathleen LoGiudice, Richard S. Ostfeld, Kenneth A. Schmidt, and Felicia Keesing
From the Cover: The ecology of infectious disease: Effects of host diversity and community composition on Lyme disease risk
PNAS 2003 100: 567-571; published online before print January 13 2003, 10.1073/pnas.0233733100 [Abstract] [Full Text] [PDF] [Supporting Table]  

Eric A. Graham, Stephen S. Mulkey, Kaoru Kitajima, Nathan G. Phillips, and S. Joseph Wright
Cloud cover limits net CO2 uptake and growth of a rainforest tree during tropical rainy seasons
PNAS 2003 100: 572-576; published online before print January 7 2003, 10.1073/pnas.0133045100 [Abstract] [Full Text] [PDF]  

Peter M. Narins, Walter Hödl, and Daniela S. Grabul
Bimodal signal requisite for agonistic behavior in a dart-poison frog, Epipedobates femoralis
PNAS 2003 100: 577-580; published online before print January 6 2003, 10.1073/pnas.0237165100 [Abstract] [Full Text] [PDF]  

Evolution

Roeland C. H. J. van Ham, Judith Kamerbeek, Carmen Palacios, Carolina Rausell, Federico Abascal, Ugo Bastolla, Jose M. Fernández, Luis Jiménez, Marina Postigo, Francisco J. Silva, Javier Tamames, Enrique Viguera, Amparo Latorre, Alfonso Valencia, Federico Morán, and Andrés Moya
Reductive genome evolution in Buchnera aphidicola
PNAS 2003 100: 581-586; published online before print January 9 2003, 10.1073/pnas.0235981100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Igor M. Rouzine, John Wakeley, and John M. Coffin
The solitary wave of asexual evolution
PNAS 2003 100: 587-592; published online before print January 13 2003, 10.1073/pnas.242719299 [Abstract] [Full Text] [PDF] [Supporting Mathematical Appendix]  

Carl T. Bergstrom and Michael Lachmann
The Red King effect: When the slowest runner wins the coevolutionary race
PNAS 2003 100: 593-598; published online before print January 13 2003, 10.1073/pnas.0134966100 [Abstract] [Full Text] [PDF]  

Peter Wilf, Kirk R. Johnson, and Brian T. Huber
Correlated terrestrial and marine evidence for global climate changes before mass extinction at the Cretaceous-Paleogene boundary
PNAS 2003 100: 599-604; published online before print January 10 2003, 10.1073/pnas.0234701100 [Abstract] [Full Text] [PDF] [Supporting Tables]  

Genetics

Vamsi K. Mootha, Pierre Lepage, Kathleen Miller, Jakob Bunkenborg, Michael Reich, Majbrit Hjerrild, Terrye Delmonte, Amelie Villeneuve, Robert Sladek, Fenghao Xu, Grant A. Mitchell, Charles Morin, Matthias Mann, Thomas J. Hudson, Brian Robinson, John D. Rioux, and Eric S. Lander
From the Cover: Identification of a gene causing human cytochrome c oxidase deficiency by integrative genomics
PNAS 2003 100: 605-610; published online before print January 14 2003, 10.1073/pnas.242716699 [Abstract] [Full Text] [PDF]  

Karel Riha and Dorothy E. Shippen
Ku is required for telomeric C-rich strand maintenance but not for end-to-end chromosome fusions in Arabidopsis
PNAS 2003 100: 611-615; published online before print January 2 2003, 10.1073/pnas.0236128100 [Abstract] [Full Text] [PDF]  

Christel Masson, Farid Menaa, Ghislaine Pinon-Lataillade, Yveline Frobert, Sylvie Chevillard, J. Pablo Radicella, Alain Sarasin, and Jaime F. Angulo
Global genome repair is required to activate KIN17, a UVC-responsive gene involved in DNA replication
PNAS 2003 100: 616-621; published online before print January 13 2003, 10.1073/pnas.0236176100 [Abstract] [Full Text] [PDF]  

Immunology

Konstantin Khalturin, Matthias Becker, Baruch Rinkevich, and Thomas C. G. Bosch
Urochordates and the origin of natural killer cells: Identification of a CD94/NKR-P1-related receptor in blood cells of Botryllus
PNAS 2003 100: 622-627; published online before print January 7 2003, 10.1073/pnas.0234104100 [Abstract] [Full Text] [PDF]  

Alexei Y. Savinov, Andrew Tcherepanov, E. Allison Green, Richard A. Flavell, and Alexander V. Chervonsky
Contribution of Fas to diabetes development
PNAS 2003 100: 628-632; published online before print January 13 2003, 10.1073/pnas.0237359100 [Abstract] [Full Text] [PDF]  

Chen-Feng Qi, Annica Martensson, Michela Mattioli, Riccardo Dalla-Favera, Victor V. Lobanenkov, and Herbert C. Morse, III
CTCF functions as a critical regulator of cell-cycle arrest and death after ligation of the B cell receptor on immature B cells
PNAS 2003 100: 633-638; published online before print January 10 2003, 10.1073/pnas.0237127100 [Abstract] [Full Text] [PDF]  

Medical Sciences

Achim A. Jungbluth, Elisabeth Stockert, H. J. Su Huang, Vincent P. Collins, Keren Coplan, Kristin Iversen, Denise Kolb, Terrance J. Johns, Andrew M. Scott, William J. Gullick, Gerd Ritter, Leonard Cohen, Matthew J. Scanlan, Webster K. Cavenee, and Lloyd J. Old
A monoclonal antibody recognizing human cancers with amplification/overexpression of the human epidermal growth factor receptor
PNAS 2003 100: 639-644; published online before print January 6 2003, 10.1073/pnas.232686499 [Abstract] [Full Text] [PDF] [Supporting Information]  

Hal E. Broxmeyer, Edward F. Srour, Giao Hangoc, Scott Cooper, Stacie A. Anderson, and David M. Bodine
High-efficiency recovery of functional hematopoietic progenitor and stem cells from human cord blood cryopreserved for 15 years
PNAS 2003 100: 645-650; published online before print January 7 2003, 10.1073/pnas.0237086100 [Abstract] [Full Text] [PDF]  

Mallik Sundaram, Yiwei Qi, Zachary Shriver, Dongfang Liu, Ganlin Zhao, Ganesh Venkataraman, Robert Langer, and Ram Sasisekharan
Rational design of low-molecular weight heparins with improved in vivo activity
PNAS 2003 100: 651-656; published online before print January 13 2003, 10.1073/pnas.252643299 [Abstract] [Full Text] [PDF] [Supporting Information]  

Shihui Liu, Hannah Aaronson, David J. Mitola, Stephen H. Leppla, and Thomas H. Bugge
Potent antitumor activity of a urokinase-activated engineered anthrax toxin
PNAS 2003 100: 657-662; published online before print January 13 2003, 10.1073/pnas.0236849100 [Abstract] [Full Text] [PDF]  

Keith A. Choate, Kristopher T. Kahle, Frederick H. Wilson, Carol Nelson-Williams, and Richard P. Lifton
WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl--transporting epithelia
PNAS 2003 100: 663-668; published online before print January 8 2003, 10.1073/pnas.242728499 [Abstract] [Full Text] [PDF]  

Rick B. Vega, Beverly A. Rothermel, Carla J. Weinheimer, Atilla Kovacs, R. H. Naseem, Rhonda Bassel-Duby, R. S. Williams, and Eric N. Olson
Dual roles of modulatory calcineurin-interacting protein 1 in cardiac hypertrophy
PNAS 2003 100: 669-674; published online before print January 6 2003, 10.1073/pnas.0237225100 [Abstract] [Full Text] [PDF]  

Christopher A. Baker and Laura Manuelidis
Unique inflammatory RNA profiles of microglia in Creutzfeldt-Jakob disease
PNAS 2003 100: 675-679; published online before print January 13 2003, 10.1073/pnas.0237313100 [Abstract] [Full Text] [PDF] [Supporting Table]  

Frederick H. Wilson, Kristopher T. Kahle, Ernesto Sabath, Maria D. Lalioti, Alicia K. Rapson, Robert S. Hoover, Steven C. Hebert, Gerardo Gamba, and Richard P. Lifton
Molecular pathogenesis of inherited hypertension with hyperkalemia: The Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4
PNAS 2003 100: 680-684; published online before print January 6 2003, 10.1073/pnas.242735399 [Abstract] [Full Text] [PDF]  

Microbiology

Takaaki Akaike, Shinichiro Okamoto, Tomohiro Sawa, Jun Yoshitake, Fumio Tamura, Koji Ichimori, Kiminori Miyazaki, Kazumi Sasamoto, and Hiroshi Maeda
8-Nitroguanosine formation in viral pneumonia and its implication for pathogenesis
PNAS 2003 100: 685-690; published online before print January 8 2003, 10.1073/pnas.0235623100 [Abstract] [Full Text] [PDF]  

Eric Batchelor and Mark Goulian
Robustness and the cycle of phosphorylation and dephosphorylation in a two-component regulatory system
PNAS 2003 100: 691-696; published online before print January 9 2003, 10.1073/pnas.0234782100 [Abstract] [Full Text] [PDF] [Supporting Text]  

Purificación López-García, Hervé Philippe, Françoise Gail, and David Moreira
Autochthonous eukaryotic diversity in hydrothermal sediment and experimental microcolonizers at the Mid-Atlantic Ridge
PNAS 2003 100: 697-702; published online before print January 9 2003, 10.1073/pnas.0235779100 [Abstract] [Full Text] [PDF]  

Neuroscience

Ann-Sofie Cans, Nathan Wittenberg, Roger Karlsson, Leslie Sombers, Mattias Karlsson, Owe Orwar, and Andrew Ewing
Artificial cells: Unique insights into exocytosis using liposomes and lipid nanotubes
PNAS 2003 100: 400-404; published online before print January 3 2003, 10.1073/pnas.232702599 [Abstract] [Full Text] [PDF]  

Ling Wang, Sandra Andersson, Margaret Warner, and Jan-Åke Gustafsson
Estrogen receptor (ER)beta knockout mice reveal a role for ERbeta in migration of cortical neurons in the developing brain
PNAS 2003 100: 703-708; published online before print January 6 2003, 10.1073/pnas.242735799 [Abstract] [Full Text] [PDF]  

Katerina Akassoglou, Eleni Douni, Jan Bauer, Hans Lassmann, George Kollias, and Lesley Probert
Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice
PNAS 2003 100: 709-714; published online before print January 9 2003, 10.1073/pnas.0236046100 [Abstract] [Full Text] [PDF]  

BethAnn McLaughlin, Karen A. Hartnett, Joseph A. Erhardt, Jeffrey J. Legos, Ray F. White, Frank C. Barone, and Elias Aizenman
Caspase 3 activation is essential for neuroprotection in preconditioning
PNAS 2003 100: 715-720; published online before print January 9 2003, 10.1073/pnas.0232966100 [Abstract] [Full Text] [PDF] [Supporting Materials & Methods]  

Fei Dou, William J. Netzer, Kentaro Tanemura, Feng Li, F. Ulrich Hartl, Akihiko Takashima, Gunnar K. Gouras, Paul Greengard, and Huaxi Xu
Chaperones increase association of tau protein with microtubules
PNAS 2003 100: 721-726; published online before print January 9 2003, 10.1073/pnas.242720499 [Abstract] [Full Text] [PDF]  

Hynek Wichterle, Manuel Alvarez-Dolado, Lynda Erskine, and Arturo Alvarez-Buylla
Permissive corridor and diffusible gradients direct medial ganglionic eminence cell migration to the neocortex
PNAS 2003 100: 727-732; published online before print January 6 2003, 10.1073/pnas.242721899 [Abstract] [Full Text] [PDF]  

Pharmacology

Nobuchika Suzuki, Susumu Nakamura, Hiroyuki Mano, and Tohru Kozasa
Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF
PNAS 2003 100: 733-738; published online before print January 6 2003, 10.1073/pnas.0234057100 [Abstract] [Full Text] [PDF]  

Hirohisa Harada, Kevin P. Pavlick, Ian N. Hines, David J. Lefer, Jason M. Hoffman, Sulaiman Bharwani, Robert E. Wolf, and Matthew B. Grisham
Sexual dimorphism in reduced-size liver ischemia and reperfusion injury in mice: Role of endothelial cell nitric oxide synthase
PNAS 2003 100: 739-744; published online before print January 9 2003, 10.1073/pnas.0235680100 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Physiology

Tibor Rohács, Coeli M. B. Lopes, Taihao Jin, Pavan P. Ramdya, Zoltán Molnár, and Diomedes E. Logothetis
Specificity of activation by phosphoinositides determines lipid regulation of Kir channels
PNAS 2003 100: 745-750; published online before print January 13 2003, 10.1073/pnas.0236364100 [Abstract] [Full Text] [PDF]  

Plant Biology

Nobukazu Shitan, Ingrid Bazin, Kazuyuki Dan, Kazuaki Obata, Koji Kigawa, Kazumitsu Ueda, Fumihiko Sato, Cyrille Forestier, and Kazufumi Yazaki
Involvement of CjMDR1, a plant multidrug-resistance-type ATP-binding cassette protein, in alkaloid transport in Coptis japonica
PNAS 2003 100: 751-756; published online before print January 10 2003, 10.1073/pnas.0134257100 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Inger Carlberg, Maria Hansson, Thomas Kieselbach, Wolfgang P. Schröder, Bertil Andersson, and Alexander V. Vener
A novel plant protein undergoing light-induced phosphorylation and release from the photosynthetic thylakoid membranes
PNAS 2003 100: 757-762; published online before print January 10 2003, 10.1073/pnas.0235452100 [Abstract] [Full Text] [PDF] [Supporting Figure]  

CORRECTIONS

Correction for Gallouzi et al., HuR binding to cytoplasmic mRNA is perturbed by heat shock, PNAS 2000 97:3073-3078 [Extract] [Full Text] [PDF]  

Correction for Williams et al., Structure and function from the circadian clock protein KaiA of Synechococcus elongatus: A potential clock input mechanism, PNAS 2002 99:15357-15362 [Extract] [Full Text] [PDF]  

Correction for Reeve et al., Overexpression, purification, and site-directed spin labeling of the Nramp metal transporter from Mycobacterium leprae, PNAS 2002 99:8608-8613 [Extract] [Full Text] [PDF]  

Correction for Vlassara et al., Inflammatory mediators are induced by dietary glycotoxins, a major risk factor for diabetic angiopathy, PNAS 2002 99:15596-15601 [Extract] [Full Text] [PDF]  

Correction for Niu et al., Stepwise contribution of each subunit to the cooperative activation of BK channels by Ca2+, PNAS 2002 99:11441-11446 [Extract] [Full Text] [PDF]  

Correction for Kilbourne et al., The total influenza vaccine failure of 1947 revisited: Major intrasubtypic antigenic change can explain failure of vaccine in a post-World War II epidemic, PNAS 2002 99:10748-10752 [Extract] [Full Text] [PDF]  

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