Find articles in this issue containing these words:

COMMENTARIES

Stephen R. Palumbi

Ecological subsidies alter the structure of marine communities
PNAS 2003 100: 11927-11928; published online before print October 6 2003, 10.1073/pnas.2335832100 [Extract] [Full Text] [PDF]  
See companion article on page 12229

Alan Rein

Genetic footprinting of a retroviral Gag gene suggests an important role in virus replication
PNAS 2003 100: 11929-11930; published online before print October 6 2003, 10.1073/pnas.2135539100 [Extract] [Full Text] [PDF]  

Richard L. Schowen

How an enzyme surmounts the activation energy barrier
PNAS 2003 100: 11931-11932; published online before print October 6 2003, 10.1073/pnas.2235806100 [Extract] [Full Text] [PDF]  
See companion article on page 12015

Michael S. Worden and John J. Foxe

The dynamics of the spread of selective visual attention
PNAS 2003 100: 11933-11935; published online before print October 6 2003, 10.1073/pnas.2135485100 [Extract] [Full Text] [PDF]  

PHYSICAL SCIENCES

Applied Mathematics

Richard Blankenbecler, Mattias Ohlsson, Carsten Peterson, and Markus Ringnér

Matching protein structures with fuzzy alignments
PNAS 2003 100: 11936-11940; published online before print October 2 2003, 10.1073/pnas.1635048100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Boualem Khouider, Andrew J. Majda, and Markos A. Katsoulakis

Coarse-grained stochastic models for tropical convection and climate
PNAS 2003 100: 11941-11946; published online before print September 30 2003, 10.1073/pnas.1634951100 [Abstract] [Full Text] [PDF]  

Applied Physical Sciences

Caesar Saloma, Gay Jane Perez, Giovanni Tapang, May Lim, and Cynthia Palmes-Saloma

Self-organized queuing and scale-free behavior in real escape panic
PNAS 2003 100: 11947-11952; published online before print September 30 2003, 10.1073/pnas.2031912100 [Abstract] [Full Text] [PDF]  

Chemistry

X. Huang, C. J. Margulis, and B. J. Berne

Dewetting-induced collapse of hydrophobic particles
PNAS 2003 100: 11953-11958; published online before print September 24 2003, 10.1073/pnas.1934837100 [Abstract] [Full Text] [PDF]  

Wen Liu, Joachim Ahlert, Qunjie Gao, Evelyn Wendt-Pienkowski, Ben Shen, and Jon S. Thorson

Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model
PNAS 2003 100: 11959-11963; published online before print October 3 2003, 10.1073/pnas.2034291100 [Abstract] [Full Text] [PDF]  

Nathalie Sordé, Gopal Das, and Stefan Matile

Enzyme screening with synthetic multifunctional pores: Focus on biopolymers
PNAS 2003 100: 11964-11969; published online before print October 6 2003, 10.1073/pnas.2132894100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Jonathan R. Nitschke and Jean-Marie Lehn

Self-organization by selection: Generation of a metallosupramolecular grid architecture by selection of components in a dynamic library of ligands
PNAS 2003 100: 11970-11974; published online before print September 29 2003, 10.1073/pnas.1534925100 [Abstract] [Full Text] [PDF]  

David P. Barondeau, Christopher D. Putnam, Carey J. Kassmann, John A. Tainer, and Elizabeth D. Getzoff

Mechanism and energetics of green fluorescent protein chromophore synthesis revealed by trapped intermediate structures
PNAS 2003 100: 12111-12116; published online before print October 1 2003, 10.1073/pnas.2133463100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Geophysics

Aaron S. Katzenstein, Lambert A. Doezema, Isobel J. Simpson, Donald R. Blake, and F. Sherwood Rowland

Extensive regional atmospheric hydrocarbon pollution in the southwestern United States
PNAS 2003 100: 11975-11979; published online before print October 6 2003, 10.1073/pnas.1635258100 [Abstract] [Full Text] [PDF]  

Physics

S. Mangan and U. Alon

Structure and function of the feed-forward loop network motif
PNAS 2003 100: 11980-11985; published online before print October 6 2003, 10.1073/pnas.2133841100 [Abstract] [Full Text] [PDF] [Supporting Tables]  

SOCIAL SCIENCES

Anthropology

J. M. Bermúdez de Castro, M. Martinón-Torres, S. Sarmiento, M. Lozano, J. L. Arsuaga, and E. Carbonell

Rates of anterior tooth wear in Middle Pleistocene hominins from Sima de los Huesos (Sierra de Atapuerca, Spain)
PNAS 2003 100: 11992-11996; published online before print October 3 2003, 10.1073/pnas.2034879100 [Abstract] [Full Text] [PDF]  

Economic Sciences

Peter Sheridan Dodds, Duncan J. Watts, and Charles F. Sabel

Information exchange and the robustness of organizational networks
PNAS 2003 100: 12516-12521; published online before print October 3 2003, 10.1073/pnas.1534702100 [Abstract] [Full Text] [PDF]  

BIOLOGICAL SCIENCES

Agricultural Sciences

Tetsuro Shinoda and Kyo Itoyama

Juvenile hormone acid methyltransferase: A key regulatory enzyme for insect metamorphosis
PNAS 2003 100: 11986-11991; published online before print October 6 2003, 10.1073/pnas.2134232100 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Applied Biological Sciences

Siyuan Tan, Dmitry Guschin, Albert Davalos, Ya-Li Lee, Andrew W. Snowden, Yann Jouvenot, H. Steven Zhang, Katherine Howes, Andrew R. McNamara, Albert Lai, Chris Ullman, Lindsey Reynolds, Michael Moore, Mark Isalan, Lutz-Peter Berg, Bradley Campos, Hong Qi, S. Kaye Spratt, Casey C. Case, Carl O. Pabo, Judith Campisi, and Philip D. Gregory

Zinc-finger protein-targeted gene regulation: Genomewide single-gene specificity
PNAS 2003 100: 11997-12002; published online before print September 26 2003, 10.1073/pnas.2035056100 [Abstract] [Full Text] [PDF]  

Biochemistry

Greg T. Cantin, Jennitte L. Stevens, and Arnold J. Berk

Activation domain–mediator interactions promote transcription preinitiation complex assembly on promoter DNA
PNAS 2003 100: 12003-12008; published online before print September 23 2003, 10.1073/pnas.2035253100 [Abstract] [Full Text] [PDF]  

Laëtitia K. Linares, Arnd Hengstermann, Aaron Ciechanover, Stefan Müller, and Martin Scheffner

HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
PNAS 2003 100: 12009-12014; published online before print September 24 2003, 10.1073/pnas.2030930100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Sun Hur and Thomas C. Bruice From the Cover: The near attack conformation approach to the study of the chorismate to prephenate reaction PNAS 2003 100: 12015-12020; published online before print October 1 2003, 10.1073/pnas.1534873100 [Abstract] [Full Text] [PDF] [Supporting Infomation]   See Commentary on page 11931

Valeria Menchise, Giuseppina De Simone, Tullia Tedeschi, Roberto Corradini, Stefano Sforza, Rosangela Marchelli, Domenica Capasso, Michele Saviano, and Carlo Pedone

Insights into peptide nucleic acid (PNA) structural features: The crystal structure of a D-lysine-based chiral PNA–DNA duplex
PNAS 2003 100: 12021-12026; published online before print September 25 2003, 10.1073/pnas.2034746100 [Abstract] [Full Text] [PDF]  

Jay D. Horton, Nila A. Shah, Janet A. Warrington, Norma N. Anderson, Sahng Wook Park, Michael S. Brown, and Joseph L. Goldstein

Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
PNAS 2003 100: 12027-12032; published online before print September 25 2003, 10.1073/pnas.1534923100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Shu He, David Bauman, Jamaine S. Davis, Alejandra Loyola, Kenichi Nishioka, Jennifer L. Gronlund, Danny Reinberg, Fanyu Meng, Neil Kelleher, and Dewey G. McCafferty

Facile synthesis of site-specifically acetylated and methylated histone proteins: Reagents for evaluation of the histone code hypothesis
PNAS 2003 100: 12033-12038; published online before print October 6 2003, 10.1073/pnas.2035256100 [Abstract] [Full Text] [PDF] [Supporting Text]  

Ermanno Gherardi, Mark E. Youles, Ricardo N. Miguel, Tom L. Blundell, Luisa Iamele, Julian Gough, Abhishek Bandyopadhyay, Guido Hartmann, and P. Jonathan G. Butler

Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor
PNAS 2003 100: 12039-12044; published online before print October 3 2003, 10.1073/pnas.2034936100 [Abstract] [Full Text] [PDF] [Supporting Table]  

Pam Tangvoranuntakul, Pascal Gagneux, Sandra Diaz, Muriel Bardor, Nissi Varki, Ajit Varki, and Elaine Muchmore

Human uptake and incorporation of an immunogenic nonhuman dietary sialic acid
PNAS 2003 100: 12045-12050; published online before print October 1 2003, 10.1073/pnas.2131556100 [Abstract] [Full Text] [PDF] [Supporting Information] [Online Correction to Supporting Table 2]  

Alireza R. Rezaie and Likui Yang

Thrombomodulin allosterically modulates the activity of the anticoagulant thrombin
PNAS 2003 100: 12051-12056; published online before print October 1 2003, 10.1073/pnas.2135346100 [Abstract] [Full Text] [PDF]  

Frank J. Grundy, Susan C. Lehman, and Tina M. Henkin

The L box regulon: Lysine sensing by leader RNAs of bacterial lysine biosynthesis genes
PNAS 2003 100: 12057-12062; published online before print October 1 2003, 10.1073/pnas.2133705100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Timothy P. Best, Benjamin S. Edelson, Nicholas G. Nickols, and Peter B. Dervan

Nuclear localization of pyrrole–imidazole polyamide–fluorescein conjugates in cell culture
PNAS 2003 100: 12063-12068; published online before print September 30 2003, 10.1073/pnas.2035074100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Bishwajit Kundu, Nilesh R. Maiti, Eric M. Jones, Krystyna A. Surewicz, David L. Vanik, and Witold K. Surewicz

Nucleation-dependent conformational conversion of the Y145Stop variant of human prion protein: Structural clues for prion propagation
PNAS 2003 100: 12069-12074; published online before print September 30 2003, 10.1073/pnas.2033281100 [Abstract] [Full Text] [PDF]  

Nicole Poulsen, Manfred Sumper, and Nils Kröger

Biosilica formation in diatoms: Characterization of native silaffin-2 and its role in silica morphogenesis
PNAS 2003 100: 12075-12080; published online before print September 24 2003, 10.1073/pnas.2035131100 [Abstract] [Full Text] [PDF]  

Erwin van Dijk, Hervé Le Hir, and Bertrand Séraphin

DcpS can act in the 5'–3' mRNA decay pathway in addition to the 3'–5' pathway
PNAS 2003 100: 12081-12086; published online before print October 1 2003, 10.1073/pnas.1635192100 [Abstract] [Full Text] [PDF]  

Angela Fago, Alvin L. Crumbliss, Jim Peterson, Linda L. Pearce, and Celia Bonaventura

The case of the missing NO– hemoglobin: Spectral changes suggestive of heme redox reactions reflect changes in NO– heme geometry
PNAS 2003 100: 12087-12092; published online before print September 26 2003, 10.1073/pnas.2032603100 [Abstract] [Full Text] [PDF]  

M. Todd Washington, Louise Prakash, and Satya Prakash

Mechanism of nucleotide incorporation opposite a thymine-thymine dimer by yeast DNA polymerase
PNAS 2003 100: 12093-12098; published online before print October 3 2003, 10.1073/pnas.2134223100 [Abstract] [Full Text] [PDF]  

Biophysics

Robert K. Adair

Noise and stochastic resonance in voltage-gated ion channels
PNAS 2003 100: 12099-12104; published online before print September 23 2003, 10.1073/pnas.2034447100 [Abstract] [Full Text] [PDF]  

Jens Meiler and David Baker

Coupled prediction of protein secondary and tertiary structure
PNAS 2003 100: 12105-12110; published online before print October 3 2003, 10.1073/pnas.1831973100 [Abstract] [Full Text] [PDF]  

David P. Barondeau, Christopher D. Putnam, Carey J. Kassmann, John A. Tainer, and Elizabeth D. Getzoff

Mechanism and energetics of green fluorescent protein chromophore synthesis revealed by trapped intermediate structures
PNAS 2003 100: 12111-12116; published online before print October 1 2003, 10.1073/pnas.2133463100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Mourad Sadqi, Lisa J. Lapidus, and Victor Muñoz

How fast is protein hydrophobic collapse?
PNAS 2003 100: 12117-12122; published online before print October 6 2003, 10.1073/pnas.2033863100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Victor Spirin and Leonid A. Mirny

Protein complexes and functional modules in molecular networks
PNAS 2003 100: 12123-12128; published online before print September 29 2003, 10.1073/pnas.2032324100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Peter G. Bolhuis

Transition-path sampling of -hairpin folding
PNAS 2003 100: 12129-12134; published online before print October 1 2003, 10.1073/pnas.1534924100 [Abstract] [Full Text] [PDF]  

Bertil Halle and Monika Davidovic

Biomolecular hydration: From water dynamics to hydrodynamics
PNAS 2003 100: 12135-12140; published online before print October 3 2003, 10.1073/pnas.2033320100 [Abstract] [Full Text] [PDF] [Supporting Table]  

Adam E. Cohen and L. Mahadevan

Kinks, rings, and rackets in filamentous structures
PNAS 2003 100: 12141-12146; published online before print October 6 2003, 10.1073/pnas.1534600100 [Abstract] [Full Text] [PDF]  

Cell Biology

Sumit K. Chanda, Suhaila White, Anthony P. Orth, Richard Reisdorph, Loren Miraglia, Russell S. Thomas, Paul DeJesus, Daniel E. Mason, Qihong Huang, Raquel Vega, De-Hua Yu, Christian G. Nelson, Brendan M. Smith, Robert Terry, Alicia S. Linford, Yang Yu, Gung-wei Chirn, Chuanzheng Song, Mark A. Labow, Dalia Cohen, Frederick J. King, Eric C. Peters, Peter G. Schultz, Peter K. Vogt, John B. Hogenesch, and Jeremy S. Caldwell From the Cover: Genome-scale functional profiling of the mammalian AP-1 signaling pathway PNAS 2003 100: 12153-12158; published online before print September 26 2003, 10.1073/pnas.1934839100 [Abstract] [Full Text] [PDF] [Supporting Information]

Giovanna Pontarin, Lisa Gallinaro, Paola Ferraro, Peter Reichard, and Vera Bianchi

Origins of mitochondrial thymidine triphosphate: Dynamic relations to cytosolic pools
PNAS 2003 100: 12159-12164; published online before print September 30 2003, 10.1073/pnas.1635259100 [Abstract] [Full Text] [PDF]  

Ming Luo, Sandra M. Jones, Marc Peters-Golden, and Thomas G. Brock

Nuclear localization of 5-lipoxygenase as a determinant of leukotriene B₄ synthetic capacity
PNAS 2003 100: 12165-12170; published online before print October 6 2003, 10.1073/pnas.2133253100 [Abstract] [Full Text] [PDF]  

Eugenia Trushina, Michael P. Heldebrant, Carmen M. Perez-Terzic, Ryan Bortolon, Irina V. Kovtun, John D. Badger, II, Andre Terzic, Alvaro Estévez, Anthony J. Windebank, Roy B. Dyer, Janet Yao, and Cynthia T. McMurray

Microtubule destabilization and nuclear entry are sequential steps leading to toxicity in Huntington's disease
PNAS 2003 100: 12171-12176; published online before print October 3 2003, 10.1073/pnas.2034961100 [Abstract] [Full Text] [PDF] [Supporting Text]  

Philipp Berger, Christiane Schaffitzel, Imre Berger, Nenad Ban, and Ueli Suter

Membrane association of myotubularin-related protein 2 is mediated by a pleckstrin homology-GRAM domain and a coiled-coil dimerization module
PNAS 2003 100: 12177-12182; published online before print October 6 2003, 10.1073/pnas.2132732100 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Maarten Hoek and Bruce Stillman

Chromatin assembly factor 1 is essential and couples chromatin assembly to DNA replication in vivo
PNAS 2003 100: 12183-12188; published online before print September 30 2003, 10.1073/pnas.1635158100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Developmental Biology

Martina Zikova, Jean-Philippe Da Ponte, Bernard Dastugue, and Krzysztof Jagla

Patterning of the cardiac outflow region in Drosophila
PNAS 2003 100: 12189-12194; published online before print September 30 2003, 10.1073/pnas.2133156100 [Abstract] [Full Text] [PDF]  

Sheila M. Bell, Claire M. Schreiner, Ronald R. Waclaw, Kenneth Campbell, S. Steven Potter, and William J. Scott From the Cover: Sp8 is crucial for limb outgrowth and neuropore closure PNAS 2003 100: 12195-12200; published online before print October 2 2003, 10.1073/pnas.2134310100 [Abstract] [Full Text] [PDF]

Nikolaus Schultz, F. Kent Hamra, and David L. Garbers

A multitude of genes expressed solely in meiotic or postmeiotic spermatogenic cells offers a myriad of contraceptive targets
PNAS 2003 100: 12201-12206; published online before print October 2 2003, 10.1073/pnas.1635054100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Yukiko Yamazaki, Mellissa R. W. Mann, Susan S. Lee, Joel Marh, John R. McCarrey, Ryuzo Yanagimachi, and Marisa S. Bartolomei

Reprogramming of primordial germ cells begins before migration into the genital ridge, making these cells inadequate donors for reproductive cloning
PNAS 2003 100: 12207-12212; published online before print September 23 2003, 10.1073/pnas.2035119100 [Abstract] [Full Text] [PDF]  

Fu-Chun Hsu, Guo-Jun Zhang, Yogendra Sinh H. Raol, Rita J. Valentino, Douglas A. Coulter, and Amy R. Brooks-Kayal

Repeated neonatal handling with maternal separation permanently alters hippocampal GABA_A receptors and behavioral stress responses
PNAS 2003 100: 12213-12218; published online before print October 6 2003, 10.1073/pnas.2131679100 [Abstract] [Full Text] [PDF]  

Ecology

Peter A. Cotton

Avian migration phenology and global climate change
PNAS 2003 100: 12219-12222; published online before print September 30 2003, 10.1073/pnas.1930548100 [Abstract] [Full Text] [PDF]  

A. M. Springer, J. A. Estes, G. B. van Vliet, T. M. Williams, D. F. Doak, E. M. Danner, K. A. Forney, and B. Pfister

Sequential megafaunal collapse in the North Pacific Ocean: An ongoing legacy of industrial whaling?
PNAS 2003 100: 12223-12228; published online before print October 2 2003, 10.1073/pnas.1635156100 [Abstract] [Full Text] [PDF]  

B. A. Menge, J. Lubchenco, M. E. S. Bracken, F. Chan, M. M. Foley, T. L. Freidenburg, S. D. Gaines, G. Hudson, C. Krenz, H. Leslie, D. N. L. Menge, R. Russell, and M. S. Webster

Coastal oceanography sets the pace of rocky intertidal community dynamics
PNAS 2003 100: 12229-12234; published online before print September 25 2003, 10.1073/pnas.1534875100 [Abstract] [Full Text] [PDF]  
See Commentary on page 11927

Evolution

Yoshihito Niimura and Masatoshi Nei

Evolution of olfactory receptor genes in the human genome
PNAS 2003 100: 12235-12240; published online before print September 24 2003, 10.1073/pnas.1635157100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Ondrej Podlaha and Jianzhi Zhang

Positive selection on protein-length in the evolution of a primate sperm ion channel
PNAS 2003 100: 12241-12246; published online before print October 1 2003, 10.1073/pnas.2033555100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Genetics

Rebecca Martone, Ghia Euskirchen, Paul Bertone, Stephen Hartman, Thomas E. Royce, Nicholas M. Luscombe, John L. Rinn, F. Kenneth Nelson, Perry Miller, Mark Gerstein, Sherman Weissman, and Michael Snyder

Distribution of NF-B-binding sites across human chromosome 22
PNAS 2003 100: 12247-12252; published online before print October 3 2003, 10.1073/pnas.2135255100 [Abstract] [Full Text] [PDF] [Supporting Tables]  

F. A. Feltus, E. K. Lee, J. F. Costello, C. Plass, and P. M. Vertino

Predicting aberrant CpG island methylation
PNAS 2003 100: 12253-12258; published online before print September 30 2003, 10.1073/pnas.2037852100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Kasper J. Kyng, Alfred May, Steen Kølvraa, and Vilhelm A. Bohr

Gene expression profiling in Werner syndrome closely resembles that of normal aging
PNAS 2003 100: 12259-12264; published online before print October 3 2003, 10.1073/pnas.2130723100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Katica Ilic, Phillip J. SanMiguel, and Jeffrey L. Bennetzen

A complex history of rearrangement in an orthologous region of the maize, sorghum, and rice genomes
PNAS 2003 100: 12265-12270; published online before print October 6 2003, 10.1073/pnas.1434476100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Jessica A. Hurt, Stacey A. Thibodeau, Andrew S. Hirsh, Carl O. Pabo, and J. Keith Joung

Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection
PNAS 2003 100: 12271-12276; published online before print October 3 2003, 10.1073/pnas.2135381100 [Abstract] [Full Text] [PDF]  

Katarina Lehmann, Petra Seemann, Sigmar Stricker, Marai Sammar, Birgit Meyer, Katrin Süring, Frank Majewski, Sigrid Tinschert, Karl-Heinz Grzeschik, Dietmar Müller, Petra Knaus, Peter Nürnberg, and Stefan Mundlos From the Cover: Mutations in bone morphogenetic protein receptor 1B cause brachydactyly type A2 PNAS 2003 100: 12277-12282; published online before print October 1 2003, 10.1073/pnas.2133476100 [Abstract] [Full Text] [PDF] [Supporting Table]

Vaishali Parikh, Yin Yao Shugart, Kimberly F. Doheny, Jie Zhang, Lan Li, John Williams, David Hayden, Brian Craig, Hilda Capo, Denise Chamblee, Cathy Chen, Mary Collins, Stuart Dankner, Dean Fiergang, David Guyton, David Hunter, Marcia Hutcheon, Marshall Keys, Nancy Morrison, Michelle Munoz, Marshall Parks, David Plotsky, Eugene Protzko, Michael X. Repka, Maria Sarubbi, Bruce Schnall, R. Michael Siatkowski, Elias Traboulsi, Joanne Waeltermann, and Jeremy Nathans

A strabismus susceptibility locus on chromosome 7p
PNAS 2003 100: 12283-12288; published online before print September 30 2003, 10.1073/pnas.2035118100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Immunology

Anne Mueller, Jani O'Rourke, Pauline Chu, Charles C. Kim, Philip Sutton, Adrian Lee, and Stanley Falkow

Protective immunity against Helicobacter is characterized by a unique transcriptional signature
PNAS 2003 100: 12289-12294; published online before print October 3 2003, 10.1073/pnas.1635231100 [Abstract] [Full Text] [PDF]  

Sheetij Dutta, J. David Haynes, J. Kathleen Moch, Arnoldo Barbosa, and David E. Lanar

Invasion-inhibitory antibodies inhibit proteolytic processing of apical membrane antigen 1 of Plasmodium falciparum merozoites
PNAS 2003 100: 12295-12300; published online before print October 2 2003, 10.1073/pnas.2032858100 [Abstract] [Full Text] [PDF]  

Joung-Woo Hong, Carl E. Allen, and Lai-Chu Wu

Inhibition of NF-B by ZAS3, a zinc-finger protein that also binds to the B motif
PNAS 2003 100: 12301-12306; published online before print October 6 2003, 10.1073/pnas.2133048100 [Abstract] [Full Text] [PDF]  

Max Löhning, Anne Richter, Torsten Stamm, Jane Hu-Li, Mario Assenmacher, William E. Paul, and Andreas Radbruch

Establishment of memory for IL-10 expression in developing T helper 2 cells requires repetitive IL-4 costimulation and does not impair proliferation
PNAS 2003 100: 12307-12312; published online before print September 26 2003, 10.1073/pnas.2035254100 [Abstract] [Full Text] [PDF]  

Medical Sciences

Hidemasa Oh, Steven B. Bradfute, Teresa D. Gallardo, Teruya Nakamura, Vinciane Gaussin, Yuji Mishina, Jennifer Pocius, Lloyd H. Michael, Richard R. Behringer, Daniel J. Garry, Mark L. Entman, and Michael D. Schneider

Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction
PNAS 2003 100: 12313-12318; published online before print October 6 2003, 10.1073/pnas.2132126100 [Abstract] [Full Text] [PDF]  

Michael L. Whitfield, Deborah R. Finlay, John Isaac Murray, Olga G. Troyanskaya, Jen-Tsan Chi, Alexander Pergamenschikov, Timothy H. McCalmont, Patrick O. Brown, David Botstein, and M. Kari Connolly

Systemic and cell type-specific gene expression patterns in scleroderma skin
PNAS 2003 100: 12319-12324; published online before print October 6 2003, 10.1073/pnas.1635114100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Praveena Gupta, Abigail A. Soyombo, John M. Shelton, Ian G. Wilkofsky, Krystyna E. Wisniewski, James A. Richardson, and Sandra L. Hofmann

Disruption of PPT2 in mice causes an unusual lysosomal storage disorder with neurovisceral features
PNAS 2003 100: 12325-12330; published online before print October 3 2003, 10.1073/pnas.2033229100 [Abstract] [Full Text] [PDF]  

Christopher C. Sullivan, Lingling Du, Danny Chu, Augustine J. Cho, Masakuni Kido, Paul L. Wolf, Stuart W. Jamieson, and Patricia A. Thistlethwaite

Induction of pulmonary hypertension by an angiopoietin 1/TIE2/serotonin pathway
PNAS 2003 100: 12331-12336; published online before print September 25 2003, 10.1073/pnas.1933740100 [Abstract] [Full Text] [PDF] [Supporting Text]  

Paola de Candia, David B. Solit, Dilip Giri, Edi Brogi, Peter M. Siegel, Adam B. Olshen, William J. Muller, Neal Rosen, and Robert Benezra

Angiogenesis impairment in Id-deficient mice cooperates with an Hsp90 inhibitor to completely suppress HER2/neu-dependent breast tumors
PNAS 2003 100: 12337-12342; published online before print October 2 2003, 10.1073/pnas.2031337100 [Abstract] [Full Text] [PDF]  

Katherine R. Kozak, Malaika W. Amneus, Suzanne M. Pusey, Feng Su, Mui N. Luong, Sam A. Luong, Srinivasa T. Reddy, and Robin Farias-Eisner

Identification of biomarkers for ovarian cancer using strong anion-exchange ProteinChips: Potential use in diagnosis and prognosis
PNAS 2003 100: 12343-12348; published online before print October 1 2003, 10.1073/pnas.2033602100 [Abstract] [Full Text] [PDF]  

Subhadra Srinivasan, Brian W. Pogue, Shudong Jiang, Hamid Dehghani, Christine Kogel, Sandra Soho, Jennifer J. Gibson, Tor D. Tosteson, Steven P. Poplack, and Keith D. Paulsen

Interpreting hemoglobin and water concentration, oxygen saturation, and scattering measured in vivo by near-infrared breast tomography
PNAS 2003 100: 12349-12354; published online before print September 26 2003, 10.1073/pnas.2032822100 [Abstract] [Full Text] [PDF]  

Julie R. McMullen, Tetsuo Shioi, Li Zhang, Oleg Tarnavski, Megan C. Sherwood, Peter M. Kang, and Seigo Izumo

Phosphoinositide 3-kinase(p110) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy
PNAS 2003 100: 12355-12360; published online before print September 24 2003, 10.1073/pnas.1934654100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Danielle B. Ulanet, Michael Torbenson, Chi V. Dang, Livia Casciola-Rosen, and Antony Rosen

Unique conformation of cancer autoantigen B23 in hepatoma: A mechanism for specificity in the autoimmune response
PNAS 2003 100: 12361-12366; published online before print September 30 2003, 10.1073/pnas.2035245100 [Abstract] [Full Text] [PDF] [Supporting Figure]  

K. S. Srinivasa Prasad, Patrick Andre, Ming He, Ming Bao, Jeanne Manganello, and David R. Phillips

Soluble CD40 ligand induces ₃ integrin tyrosine phosphorylation and triggers platelet activation by outside-in signaling
PNAS 2003 100: 12367-12371; published online before print September 30 2003, 10.1073/pnas.2032886100 [Abstract] [Full Text] [PDF]  

Yong-Yuan Zhang, Bai-Hua Zhang, Daniel Theele, Samuel Litwin, Eugene Toll, and Jesse Summers

Single-cell analysis of covalently closed circular DNA copy numbers in a hepadnavirus-infected liver
PNAS 2003 100: 12372-12377; published online before print October 3 2003, 10.1073/pnas.2033898100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Yasutomi Kamei, Hiroshi Ohizumi, Yasushi Fujitani, Tomoyuki Nemoto, Toshiya Tanaka, Nobuyuki Takahashi, Teruo Kawada, Masamitsu Miyoshi, Osamu Ezaki, and Akira Kakizuka

PPAR coactivator 1/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity
PNAS 2003 100: 12378-12383; published online before print October 6 2003, 10.1073/pnas.2135217100 [Abstract] [Full Text] [PDF]  

Andreas G. Bader, Katherine A. Felts, Ning Jiang, Hwai Wen Chang, and Peter K. Vogt

Y box-binding protein 1 induces resistance to oncogenic transformation by the phosphatidylinositol 3-kinase pathway
PNAS 2003 100: 12384-12389; published online before print October 6 2003, 10.1073/pnas.2135336100 [Abstract] [Full Text] [PDF]  

Willemijn Vader, Dariusz Stepniak, Yvonne Kooy, Luisa Mearin, Allan Thompson, Jon J. van Rood, Liesbeth Spaenij, and Frits Koning

The HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses
PNAS 2003 100: 12390-12395; published online before print October 6 2003, 10.1073/pnas.2135229100 [Abstract] [Full Text] [PDF]  

Microbiology

Dong Yu, Maria C. Silva, and Thomas Shenk

Functional map of human cytomegalovirus AD169 defined by global mutational analysis
PNAS 2003 100: 12396-12401; published online before print September 30 2003, 10.1073/pnas.1635160100 [Abstract] [Full Text] [PDF] [Supporting Table]  

Carlos Lopez-Estraño, Souvik Bhattacharjee, Travis Harrison, and Kasturi Haldar

Cooperative domains define a unique host cell-targeting signal in Plasmodium falciparum-infected erythrocytes
PNAS 2003 100: 12402-12407; published online before print September 26 2003, 10.1073/pnas.2133080100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Brunella Taddeo, Ting Rong Luo, Weiran Zhang, and Bernard Roizman

Activation of NF-B in cells productively infected with HSV-1 depends on activated protein kinase R and plays no apparent role in blocking apoptosis
PNAS 2003 100: 12408-12413; published online before print October 6 2003, 10.1073/pnas.2034952100 [Abstract] [Full Text] [PDF]  

Juan Martin-Serrano, Anton Yarovoy, David Perez-Caballero, and Paul D. Bieniasz

Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins
PNAS 2003 100: 12414-12419; published online before print September 30 2003, 10.1073/pnas.2133846100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Tsungda Hsu, Suzanne M. Hingley-Wilson, Bing Chen, Mei Chen, Annie Z. Dai, Paul M. Morin, Carolyn B. Marks, Jeevan Padiyar, Celia Goulding, Mari Gingery, David Eisenberg, Robert G. Russell, Steven C. Derrick, Frank M. Collins, Sheldon L. Morris, C. Harold King, and William R. Jacobs, Jr.

The primary mechanism of attenuation of bacillus Calmette–Guérin is a loss of secreted lytic function required for invasion of lung interstitial tissue
PNAS 2003 100: 12420-12425; published online before print October 13 2003, 10.1073/pnas.1635213100 [Abstract] [Full Text] [PDF]  

Isabelle I. Salles, Amy E. Tucker, Daniel E. Voth, and Jimmy D. Ballard

Toxin-induced resistance in Bacillus anthracis lethal toxin-treated macrophages
PNAS 2003 100: 12426-12431; published online before print September 30 2003, 10.1073/pnas.2134042100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Laurel L. Lenz, Sina Mohammadi, Aimee Geissler, and Daniel A. Portnoy

SecA2-dependent secretion of autolytic enzymes promotes Listeria monocytogenes pathogenesis
PNAS 2003 100: 12432-12437; published online before print October 3 2003, 10.1073/pnas.2133653100 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Neuroscience

Zhizhong Dong, Boris Ferger, Jean-Charles Paterna, Denise Vogel, Sven Furler, Maribel Osinde, Joram Feldon, and Hansruedi Büeler

Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the parkin target protein, CDCrel-1
PNAS 2003 100: 12438-12443; published online before print October 6 2003, 10.1073/pnas.2132992100 [Abstract] [Full Text] [PDF]  

William J. Netzer, Fei Dou, Dongming Cai, Darren Veach, Stephanie Jean, Yueming Li, William G. Bornmann, Bayard Clarkson, Huaxi Xu, and Paul Greengard

Gleevec inhibits -amyloid production but not Notch cleavage
PNAS 2003 100: 12444-12449; published online before print October 1 2003, 10.1073/pnas.1534745100 [Abstract] [Full Text] [PDF]  

J. Breustedt, K. E. Vogt, R. J. Miller, R. A. Nicoll, and D. Schmitz

_1E-Containing Ca²⁺ channels are involved in synaptic plasticity
PNAS 2003 100: 12450-12455; published online before print September 30 2003, 10.1073/pnas.2035117100 [Abstract] [Full Text] [PDF]  

Jean-Yves Chatton, Luc Pellerin, and Pierre J. Magistretti

GABA uptake into astrocytes is not associated with significant metabolic cost: Implications for brain imaging of inhibitory transmission
PNAS 2003 100: 12456-12461; published online before print October 6 2003, 10.1073/pnas.2132096100 [Abstract] [Full Text] [PDF]  

Brian J. Bacskai, Gregory A. Hickey, Jesse Skoch, Stephen T. Kajdasz, Yanming Wang, Guo-feng Huang, Chester A. Mathis, William E. Klunk, and Bradley T. Hyman

Four-dimensional multiphoton imaging of brain entry, amyloid binding, and clearance of an amyloid- ligand in transgenic mice
PNAS 2003 100: 12462-12467; published online before print September 29 2003, 10.1073/pnas.2034101100 [Abstract] [Full Text] [PDF] [Supporting Movies]  

Javier Morante-Oria, Alan Carleton, Barbara Ortino, Eric J. Kremer, Alfonso Fairén, and Pierre-Marie Lledo

Subpallial origin of a population of projecting pioneer neurons during corticogenesis
PNAS 2003 100: 12468-12473; published online before print October 1 2003, 10.1073/pnas.1633692100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Bagrat Amirikian and Apostolos P. Georgopoulos

Modular organization of directionally tuned cells in the motor cortex: Is there a short-range order?
PNAS 2003 100: 12474-12479; published online before print October 1 2003, 10.1073/pnas.2037719100 [Abstract] [Full Text] [PDF]  

Gautam Bhave, Hui-Juan Hu, Kathi S. Glauner, Weiguo Zhu, Haibin Wang, D. J. Brasier, Gerry S. Oxford, and Robert W. Gereau, IV From The Cover: Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1) PNAS 2003 100: 12480-12485; published online before print October 1 2003, 10.1073/pnas.2032100100 [Abstract] [Full Text] [PDF]

Laura Gianfranceschi, Rosita Siciliano, Jennifer Walls, Bernardo Morales, Alfredo Kirkwood, Z. Josh Huang, Susumu Tonegawa, and Lamberto Maffei

Visual cortex is rescued from the effects of dark rearing by overexpression of BDNF
PNAS 2003 100: 12486-12491; published online before print September 26 2003, 10.1073/pnas.1934836100 [Abstract] [Full Text] [PDF]  

Maria Korman, Naftali Raz, Tamar Flash, and Avi Karni

Multiple shifts in the representation of a motor sequence during the acquisition of skilled performance
PNAS 2003 100: 12492-12497; published online before print October 6 2003, 10.1073/pnas.2035019100 [Abstract] [Full Text] [PDF]  

Pharmacology