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Table of Contents

January 6, 2004; 101 (1)  [Index By Author]  [Cover Photo]

FROM THE COVER

In vivo RNAi in the retina

Mimicking limbless locomotion

Assessing methylation and epigenetic fidelity

A kinase defense against viruses

Another polymorphism for malaria protection

EDITORIAL

COMMENTARIES

PERSPECTIVES

PHYSICAL SCIENCES
    Applied Physical Sciences
    Geophysics
    Physics

SOCIAL SCIENCES

BIOLOGICAL SCIENCES
    Biochemistry
    Biophysics
    Cell Biology
    Developmental Biology
    Ecology
    Evolution
    Genetics

    Immunology
    Medical Sciences
    Microbiology
    Neuroscience
    Pharmacology
    Physiology
    Plant Biology
    Population Biology

CORRECTIONS

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EDITORIAL

Nicholas R. Cozzarelli, Kenneth R. Fulton, and Diane M. Sullenberger
PNAS goes weekly in the new year
PNAS 2004 101: 1. [Extract] [Full Text] [PDF]  

COMMENTARIES

R. A. Harris and S. J. Mihic
Alcohol and inhibitory receptors: Unexpected specificity from a nonspecific drug
PNAS 2004 101: 2-3; published online before print December 26 2003, 10.1073/pnas.0307281101 [Extract] [Full Text] [PDF]  

Arthur D. Riggs and Zhenggang Xiong
Methylation and epigenetic fidelity
PNAS 2004 101: 4-5; published online before print December 26 2003, 10.1073/pnas.0307781100 [Extract] [Full Text] [PDF]  
See companion article on page 204

Harry W. Green, II
Shock-induced minerals in meteorite provide prospecting tools for mineral physics
PNAS 2004 101: 6-7; published online before print December 26 2003, 10.1073/pnas.0307628100 [Extract] [Full Text] [PDF]  

PERSPECTIVES

Robert P. Kirshner
Hubble's diagram and cosmic expansion
PNAS 2004 101: 8-13; published online before print December 26 2003, 10.1073/pnas.2536799100 [Abstract] [Full Text] [PDF] [Supporting Table]  

PHYSICAL SCIENCES

Applied Physical Sciences

L. Mahadevan, S. Daniel, and M. K. Chaudhury
From the Cover: Biomimetic ratcheting motion of a soft, slender, sessile gel
PNAS 2004 101: 23-26; published online before print December 17 2003, 10.1073/pnas.2637051100 [Abstract] [Full Text] [PDF] [Supporting Movies]  

Geophysics

Noah S. Diffenbaugh, Mark A. Snyder, and Lisa C. Sloan
Could CO2-induced land-cover feedbacks alter near-shore upwelling regimes?
PNAS 2004 101: 27-32; published online before print December 22 2003, 10.1073/pnas.0305746101 [Abstract] [Full Text] [PDF]  

Physics

Gerd Steinle-Neumann, Lars Stixrude, and Ronald E. Cohen
Magnetism in dense hexagonal iron
PNAS 2004 101: 33-36; published online before print December 23 2003, 10.1073/pnas.2237239100 [Abstract] [Full Text] [PDF]  

SOCIAL SCIENCES

BIOLOGICAL SCIENCES

Biochemistry

I. Ruiz-Stewart, S. R. Tiyyagura, J. E. Lin, S. Kazerounian, G. M. Pitari, S. Schulz, E. Martin, F. Murad, and S. A. Waldman
Guanylyl cyclase is an ATP sensor coupling nitric oxide signaling to cell metabolism
PNAS 2004 101: 37-42; published online before print December 18 2003, 10.1073/pnas.0305080101 [Abstract] [Full Text] [PDF]  

Jiang-Wen Zhang, Qi-Qun Tang, Charles Vinson, and M. Daniel Lane
Dominant-negative C/EBP disrupts mitotic clonal expansion and differentiation of 3T3-L1 preadipocytes
PNAS 2004 101: 43-47; published online before print December 19 2003, 10.1073/pnas.0307229101 [Abstract] [Full Text] [PDF]  

Tetsuya Miyamoto, Junichi Obokata, and Masahiro Sugiura
A site-specific factor interacts directly with its cognate RNA editing site in chloroplast transcripts
PNAS 2004 101: 48-52; published online before print December 23 2003, 10.1073/pnas.0307163101 [Abstract] [Full Text] [PDF]  

Kapil Kumar, Michael Brady, and Robert Shapiro
Selective abolition of pancreatic RNase binding to its inhibitor protein
PNAS 2004 101: 53-58; published online before print December 17 2003, 10.1073/pnas.0307268101 [Abstract] [Full Text] [PDF]  

Momi Iwata, Hiromi Imamura, Elizabeth Stambouli, Chiyo Ikeda, Masatada Tamakoshi, Koji Nagata, Hisayoshi Makyio, Ben Hankamer, Jim Barber, Masasuke Yoshida, Ken Yokoyama, and So Iwata
Crystal structure of a central stalk subunit C and reversible association/dissociation of vacuole-type ATPase
PNAS 2004 101: 59-64; published online before print December 18 2003, 10.1073/pnas.0305165101 [Abstract] [Full Text] [PDF]  

Daniel J.-F. Chinnapen and Dipankar Sen
A deoxyribozyme that harnesses light to repair thymine dimers in DNA
PNAS 2004 101: 65-69; published online before print December 22 2003, 10.1073/pnas.0305943101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Vasiliki E. Fadouloglou, Anastasia P. Tampakaki, Nicholas M. Glykos, Marina N. Bastaki, Jonathan M. Hadden, Simon E. Phillips, Nicholas J. Panopoulos, and Michael Kokkinidis
Structure of HrcQB-C, a conserved component of the bacterial type III secretion systems
PNAS 2004 101: 70-75; published online before print December 23 2003, 10.1073/pnas.0304579101 [Abstract] [Full Text] [PDF]  

Takashi Tsuboi, Jonathan D. Lippiat, Frances M. Ashcroft, and Guy A. Rutter
ATP-dependent interaction of the cytosolic domains of the inwardly rectifying K+ channel Kir6.2 revealed by fluorescence resonance energy transfer
PNAS 2004 101: 76-81; published online before print December 17 2003, 10.1073/pnas.0306347101 [Abstract] [Full Text] [PDF]  

Shuji Hanai, Masayuki Kanai, Sayaka Ohashi, Keiji Okamoto, Mitsunori Yamada, Hitoshi Takahashi, and Masanao Miwa
Loss of poly(ADP-ribose) glycohydrolase causes progressive neurodegeneration in Drosophila melanogaster
PNAS 2004 101: 82-86; published online before print December 15 2003, 10.1073/pnas.2237114100 [Abstract] [Full Text] [PDF]  

Manuela López de la Paz and Luis Serrano
Sequence determinants of amyloid fibril formation
PNAS 2004 101: 87-92; published online before print December 22 2003, 10.1073/pnas.2634884100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Girish C. Shukla and Richard A. Padgett
U4 small nuclear RNA can function in both the major and minor spliceosomes
PNAS 2004 101: 93-98; published online before print December 22 2003, 10.1073/pnas.0304919101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Jianyin Long, Guannan Wang, Isao Matsuura, Dongming He, and Fang Liu
Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3)
PNAS 2004 101: 99-104; published online before print December 22 2003, 10.1073/pnas.0307598100 [Abstract] [Full Text] [PDF]  

Biophysics

L. Mahadevan, S. Daniel, and M. K. Chaudhury
From the Cover: Biomimetic ratcheting motion of a soft, slender, sessile gel
PNAS 2004 101: 23-26; published online before print December 17 2003, 10.1073/pnas.2637051100 [Abstract] [Full Text] [PDF] [Supporting Movies]  

Sally A. Kim, Katrin G. Heinze, M. Neal Waxham, and Petra Schwille
Intracellular calmodulin availability accessed with two-photon cross-correlation
PNAS 2004 101: 105-110; published online before print December 26 2003, 10.1073/pnas.2436461100 [Abstract] [Full Text] [PDF]  

Rajul K. Jain and Rama Ranganathan
Local complexity of amino acid interactions in a protein core
PNAS 2004 101: 111-116; published online before print December 18 2003, 10.1073/pnas.2534352100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Toby W. Allen, Olaf S. Andersen, and Benoît Roux
Energetics of ion conduction through the gramicidin channel
PNAS 2004 101: 117-122; published online before print December 22 2003, 10.1073/pnas.2635314100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Jan M. Kriegl and G. Ulrich Nienhaus
Structural, dynamic, and energetic aspects of long-range electron transfer in photosynthetic reaction centers
PNAS 2004 101: 123-128; published online before print December 22 2003, 10.1073/pnas.2434740100 [Abstract] [Full Text] [PDF]  

H. L. Grossman, W. R. Myers, V. J. Vreeland, R. Bruehl, M. D. Alper, C. R. Bertozzi, and John Clarke
Detection of bacteria in suspension by using a superconducting quantum interference device
PNAS 2004 101: 129-134; published online before print December 19 2003, 10.1073/pnas.0307128101 [Abstract] [Full Text] [PDF]  

Cell Biology

Lianxing Zheng, Jun Liu, Sergei Batalov, Demin Zhou, Anthony Orth, Sheng Ding, and Peter G. Schultz
An approach to genomewide screens of expressed small interfering RNAs in mammalian cells
PNAS 2004 101: 135-140; published online before print December 19 2003, 10.1073/pnas.2136685100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Micah Luftig, Teruhito Yasui, Vishal Soni, Myung-Soo Kang, Nils Jacobson, Ellen Cahir-McFarland, Brian Seed, and Elliott Kieff
Epstein–Barr virus latent infection membrane protein 1 TRAF-binding site induces NIK/IKK{alpha}-dependent noncanonical NF-{kappa}B activation
PNAS 2004 101: 141-146; published online before print December 22 2003, 10.1073/pnas.2237183100 [Abstract] [Full Text] [PDF]  

Shahab Uddin, Jeong Ah-Kang, Jodie Ulaszek, Dolores Mahmud, and Amittha Wickrema
Differentiation stage-specific activation of p38 mitogen-activated protein kinase isoforms in primary human erythroid cells
PNAS 2004 101: 147-152; published online before print December 23 2003, 10.1073/pnas.0307075101 [Abstract] [Full Text] [PDF]  

Xingming Deng, Fengqin Gao, Tammy Flagg, and W. Stratford May, Jr.
Mono- and multisite phosphorylation enhances Bcl2's antiapoptotic function and inhibition of cell cycle entry functions
PNAS 2004 101: 153-158; published online before print December 5 2003, 10.1073/pnas.2533920100 [Abstract] [Full Text] [PDF]  

Developmental Biology

Yong-Ou Kim, Sang-Joon Park, Robert S. Balaban, Marshall Nirenberg, and Yongsok Kim
A functional genomic screen for cardiogenic genes using RNA interference in developing Drosophila embryos
PNAS 2004 101: 159-164; published online before print December 18 2003, 10.1073/pnas.0307205101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Nicholas Marsh-Armstrong, Liquan Cai, and Donald D. Brown
Thyroid hormone controls the development of connections between the spinal cord and limbs during Xenopus laevis metamorphosis
PNAS 2004 101: 165-170; published online before print December 22 2003, 10.1073/pnas.2136755100 [Abstract] [Full Text] [PDF] [Supporting Movies]  

Ecology

P. Choler, B. Erschbamer, A. Tribsch, L. Gielly, and P. Taberlet
Genetic introgression as a potential to widen a species' niche: Insights from alpine Carex curvula
PNAS 2004 101: 171-176; published online before print December 22 2003, 10.1073/pnas.2237235100 [Abstract] [Full Text] [PDF] [Supporting Text]  

Thomas W. Schoener, David A. Spiller, and Jonathan B. Losos
Variable ecological effects of hurricanes: The importance of seasonal timing for survival of lizards on Bahamian islands
PNAS 2004 101: 177-181; published online before print December 26 2003, 10.1073/pnas.0306887101 [Abstract] [Full Text] [PDF]  

Gary W. Luck, Taylor H. Ricketts, Gretchen C. Daily, and Marc Imhoff
Alleviating spatial conflict between people and biodiversity
PNAS 2004 101: 182-186; published online before print December 17 2003, 10.1073/pnas.2237148100 [Abstract] [Full Text] [PDF]  

Evolution

James L. Cornette and Bruce S. Lieberman
Random walks in the history of life
PNAS 2004 101: 187-191; published online before print December 18 2003, 10.1073/pnas.2637009100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Genetics

Swati S. Sathe, Nywana Sizemore, Xiaoxia Li, Kalpa Vithalani, Mairead Commane, Shannon M. Swiatkowski, and George R. Stark
Mutant human cells with constitutive activation of NF-{kappa}B
PNAS 2004 101: 192-197; published online before print December 22 2003, 10.1073/pnas.0306812101 [Abstract] [Full Text] [PDF]  

Zhengmei Mao, Gregg Roman, Lin Zong, and Ronald L. Davis
Pharmacogenetic rescue in time and space of the rutabaga memory impairment by using Gene-Switch
PNAS 2004 101: 198-203; published online before print December 18 2003, 10.1073/pnas.0306128101 [Abstract] [Full Text] [PDF]  

Charles D. Laird, Nicole D. Pleasant, Aaron D. Clark, Jessica L. Sneeden, K. M. Anwarul Hassan, Nathan C. Manley, Jay C. Vary, Jr., Todd Morgan, R. Scott Hansen, and Reinhard Stöger
From The Cover: Hairpin-bisulfite PCR: Assessing epigenetic methylation patterns on complementary strands of individual DNA molecules
PNAS 2004 101: 204-209; published online before print December 12 2003, 10.1073/pnas.2536758100 [Abstract] [Full Text] [PDF] [Supporting Figures]  
See Commentary on page 4

Immunology

Stephan Kissler, Linrong Lu, and Harvey Cantor
Thymic selection can compensate for mutations affecting T cell activation and generate a normal T cell repertoire in mutant mice
PNAS 2004 101: 210-214; published online before print December 23 2003, 10.1073/pnas.0307202101 [Abstract] [Full Text] [PDF]  

Young-Sun Kang, Jae Y. Kim, Sandra A. Bruening, Maggi Pack, Anna Charalambous, Alla Pritsker, Thomas M. Moran, Jutta M. Loeffler, Ralph M. Steinman, and Chae Gyu Park
The C-type lectin SIGN-R1 mediates uptake of the capsular polysaccharide of Streptococcus pneumoniae in the marginal zone of mouse spleen
PNAS 2004 101: 215-220; published online before print December 23 2003, 10.1073/pnas.0307124101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Yu-An Cao, Amy J. Wagers, Andreas Beilhack, Joan Dusich, Michael H. Bachmann, Robert S. Negrin, Irving L. Weissman, and Christopher H. Contag
Shifting foci of hematopoiesis during reconstitution from single stem cells
PNAS 2004 101: 221-226; published online before print December 19 2003, 10.1073/pnas.2637010100 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Heike Schäcke, Arndt Schottelius, Wolf-Dietrich Döcke, Peter Strehlke, Stefan Jaroch, Norbert Schmees, Hartmut Rehwinkel, Hartwig Hennekes, and Khusru Asadullah
Dissociation of transactivation from transrepression by a selective glucocorticoid receptor agonist leads to separation of therapeutic effects from side effects
PNAS 2004 101: 227-232; published online before print December 23 2003, 10.1073/pnas.0300372101 [Abstract] [Full Text] [PDF]  

Sarah M. McWhirter, Katherine A. Fitzgerald, Jacqueline Rosains, Daniel C. Rowe, Douglas T. Golenbock, and Tom Maniatis
From The Cover: IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts
PNAS 2004 101: 233-238; published online before print December 16 2003, 10.1073/pnas.2237236100 [Abstract] [Full Text] [PDF]  

Donna Hochberg, Jaap M. Middeldorp, Michelle Catalina, John L. Sullivan, Katherine Luzuriaga, and David A. Thorley-Lawson
Demonstration of the Burkitt's lymphoma Epstein-Barr virus phenotype in dividing latently infected memory cells in vivo
PNAS 2004 101: 239-244; published online before print December 19 2003, 10.1073/pnas.2237267100 [Abstract] [Full Text] [PDF]  

Caius G. Radu, Li V. Yang, Mireille Riedinger, Matthew Au, and Owen N. Witte
T cell chemotaxis to lysophosphatidylcholine through the G2A receptor
PNAS 2004 101: 245-250; published online before print December 17 2003, 10.1073/pnas.2536801100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Elvira R. Eivazova and Thomas M. Aune
Dynamic alterations in the conformation of the Ifng gene region during T helper cell differentiation
PNAS 2004 101: 251-256; published online before print December 22 2003, 10.1073/pnas.0303919101 [Abstract] [Full Text] [PDF]  

Renata Pasqualini and Wadih Arap
Hybridoma-free generation of monoclonal antibodies
PNAS 2004 101: 257-259; published online before print December 19 2003, 10.1073/pnas.0305834101 [Abstract] [Full Text] [PDF]  

Na Xiong, Jeanne E. Baker, Chulho Kang, and David H. Raulet
The genomic arrangement of T cell receptor variable genes is a determinant of the developmental rearrangement pattern
PNAS 2004 101: 260-265; published online before print December 22 2003, 10.1073/pnas.0303738101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Medical Sciences

Frank Kuhnert, Corrine R. Davis, Hsiao-Ting Wang, Pauline Chu, Mark Lee, Jenny Yuan, Roel Nusse, and Calvin J. Kuo
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1
PNAS 2004 101: 266-271; published online before print December 26 2003, 10.1073/pnas.2536800100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Ian A. Cockburn, Margaret J. Mackinnon, Angela O'Donnell, Stephen J. Allen, Joann M. Moulds, Moses Baisor, Moses Bockarie, John C. Reeder, and J. Alexandra Rowe
From The Cover: A human complement receptor 1 polymorphism that reduces Plasmodium falciparum rosetting confers protection against severe malaria
PNAS 2004 101: 272-277; published online before print December 23 2003, 10.1073/pnas.0305306101 [Abstract] [Full Text] [PDF]  

Teruhito Yasui, Micah Luftig, Vishal Soni, and Elliott Kieff
Latent infection membrane protein transmembrane FWLY is critical for intermolecular interaction, raft localization, and signaling
PNAS 2004 101: 278-283; published online before print December 26 2003, 10.1073/pnas.2237224100 [Abstract] [Full Text] [PDF]  

Eric M. Reiman, Kewei Chen, Gene E. Alexander, Richard J. Caselli, Daniel Bandy, David Osborne, Ann M. Saunders, and John Hardy
Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia
PNAS 2004 101: 284-289; published online before print December 19 2003, 10.1073/pnas.2635903100 [Abstract] [Full Text] [PDF]  

Eric Prieur, Sarah C. Gilbert, Joerg Schneider, Anne C. Moore, Eric G. Sheu, Nilu Goonetilleke, Kathryn J. H. Robson, and Adrian V. S. Hill
A Plasmodium falciparum candidate vaccine based on a six-antigen polyprotein encoded by recombinant poxviruses
PNAS 2004 101: 290-295; published online before print December 23 2003, 10.1073/pnas.0307158101 [Abstract] [Full Text] [PDF]  

Huan Yang, Mahendar Ochani, Jianhua Li, Xiaoling Qiang, Mahira Tanovic, Helena E. Harris, Srinivas M. Susarla, Luis Ulloa, Hong Wang, Robert DiRaimo, Christopher J. Czura, Haichao Wang, Jesse Roth, H. Shaw Warren, Mitchell P. Fink, Matthew J. Fenton, Ulf Andersson, and Kevin J. Tracey
Reversing established sepsis with antagonists of endogenous high-mobility group box 1
PNAS 2004 101: 296-301; published online before print December 26 2003, 10.1073/pnas.2434651100 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Microbiology

Minfeng Zhu, Feng Shao, Roger W. Innes, Jack E. Dixon, and Zhaohui Xu
The crystal structure of Pseudomonas avirulence protein AvrPphB: A papain-like fold with a distinct substrate-binding site
PNAS 2004 101: 302-307; published online before print December 23 2003, 10.1073/pnas.2036536100 [Abstract] [Full Text] [PDF] [Supporting Table]  

Estela Area, Jaime Martín-Benito, Pablo Gastaminza, Eva Torreira, José M. Valpuesta, José L. Carrascosa, and Juan Ortín
3D structure of the influenza virus polymerase complex: Localization of subunit domains
PNAS 2004 101: 308-313; published online before print December 22 2003, 10.1073/pnas.0307127101 [Abstract] [Full Text] [PDF]  

Damien Portevin, Célia de Sousa-D'Auria, Christine Houssin, Christine Grimaldi, Mohamed Chami, Mamadou Daffé, and Christophe Guilhot
A polyketide synthase catalyzes the last condensation step of mycolic acid biosynthesis in mycobacteria and related organisms
PNAS 2004 101: 314-319; published online before print December 26 2003, 10.1073/pnas.0305439101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Neuroscience

Christen Brownlee
Inaugural Article by a Recently Elected Academy Member:
Inaugural Article: Biography of Constance L. Cepko
PNAS 2004 101: 14-15; published online before print December 26 2003, 10.1073/pnas.0307955100 [Extract] [Full Text] [PDF]  

Takahiko Matsuda and Constance L. Cepko
Inaugural Article by a Recently Elected Academy Member:
Inaugural Article: Electroporation and RNA interference in the rodent retina in vivo and in vitro
PNAS 2004 101: 16-22; published online before print November 5 2003, 10.1073/pnas.2235688100 [Abstract] [Full Text] [PDF] [Supporting Figures]  

D. M. Mooney, L. Zhang, C. Basile, V. V. Senatorov, J. Ngsee, A. Omar, and B. Hu
Distinct forms of cholinergic modulation in parallel thalamic sensory pathways
PNAS 2004 101: 320-324; published online before print December 22 2003, 10.1073/pnas.0304445101 [Abstract] [Full Text] [PDF]  

Ludovic Collin, Alessandro Usiello, Eric Erbs, Carole Mathis, and Emiliana Borrelli
Motor training compensates for cerebellar dysfunctions caused by oligodendrocyte ablation
PNAS 2004 101: 325-330; published online before print December 23 2003, 10.1073/pnas.0305994101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Klaus Dinkel, Firdaus S. Dhabhar, and Robert M. Sapolsky
Neurotoxic effects of polymorphonuclear granulocytes on hippocampal primary cultures
PNAS 2004 101: 331-336; published online before print December 18 2003, 10.1073/pnas.0303510101 [Abstract] [Full Text] [PDF]  

J. J. Hopfield and Carlos D. Brody
Learning rules and network repair in spike-timing-based computation networks
PNAS 2004 101: 337-342; published online before print December 23 2003, 10.1073/pnas.2536316100 [Abstract] [Full Text] [PDF]  

Kunlin Jin, Alyson L. Peel, Xiao Ou Mao, Lin Xie, Barbara A. Cottrell, David C. Henshall, and David A. Greenberg
Increased hippocampal neurogenesis in Alzheimer's disease
PNAS 2004 101: 343-347; published online before print December 5 2003, 10.1073/pnas.2634794100 [Abstract] [Full Text] [PDF]  

M. Veldic, H. J. Caruncho, W. S. Liu, J. Davis, R. Satta, D. R. Grayson, A. Guidotti, and E. Costa
DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains
PNAS 2004 101: 348-353; published online before print December 18 2003, 10.1073/pnas.2637013100 [Abstract] [Full Text] [PDF]  

Takashi Yoshitake, Fu-Hua Wang, Eugenia Kuteeva, Kristina Holmberg, Masatoshi Yamaguchi, Jacqueline N. Crawley, Robert Steiner, Tamas Bartfai, Sven Ove Ögren, Tomas Hökfelt, and Jan Kehr
Enhanced hippocampal noradrenaline and serotonin release in galanin-overexpressing mice after repeated forced swimming test
PNAS 2004 101: 354-359; published online before print December 30 2003, 10.1073/pnas.0307042101 [Abstract] [Full Text] [PDF]  

John Kim, Anna Krichevsky, Yonatan Grad, Gabriel D. Hayes, Kenneth S. Kosik, George M. Church, and Gary Ruvkun
Identification of many microRNAs that copurify with polyribosomes in mammalian neurons
PNAS 2004 101: 360-365; published online before print December 22 2003, 10.1073/pnas.2333854100 [Abstract] [Full Text] [PDF] [Supporting Information]  

Louis Tao, Michael Shelley, David McLaughlin, and Robert Shapley
An egalitarian network model for the emergence of simple and complex cells in visual cortex
PNAS 2004 101: 366-371; published online before print December 26 2003, 10.1073/pnas.2036460100 [Abstract] [Full Text] [PDF] [Supporting Text]  

Yolanda Mateo, Evgeny A. Budygin, Carrie E. John, and Sara R. Jones
Role of serotonin in cocaine effects in mice with reduced dopamine transporter function
PNAS 2004 101: 372-377; published online before print December 22 2003, 10.1073/pnas.0207805101 [Abstract] [Full Text] [PDF]  

Pharmacology

Cyril Goudet, Florence Gaven, Julie Kniazeff, Claire Vol, Jiangfeng Liu, Martin Cohen-Gonsaud, Francine Acher, Laurent Prézeau, and Jean Philippe Pin
Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors
PNAS 2004 101: 378-383; published online before print December 22 2003, 10.1073/pnas.0304699101 [Abstract] [Full Text] [PDF]  

Physiology

Anup Ramachandran, Erin Ceaser, and Victor M. Darley-Usmar
Chronic exposure to nitric oxide alters the free iron pool in endothelial cells: Role of mitochondrial respiratory complexes and heat shock proteins
PNAS 2004 101: 384-389; published online before print December 22 2003, 10.1073/pnas.0304653101 [Abstract] [Full Text] [PDF]  

Valerie Chappe, Deborah A. Hinkson, L. Daniel Howell, Alexandra Evagelidis, Jie Liao, Xiu-Bao Chang, John R. Riordan, and John W. Hanrahan
Stimulatory and inhibitory protein kinase C consensus sequences regulate the cystic fibrosis transmembrane conductance regulator
PNAS 2004 101: 390-395; published online before print December 26 2003, 10.1073/pnas.0303411101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

J. Vriens, H. Watanabe, A. Janssens, G. Droogmans, T. Voets, and B. Nilius
Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4
PNAS 2004 101: 396-401; published online before print December 22 2003, 10.1073/pnas.0303329101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Plant Biology

Li Tian, Valeria Musetti, Joonyul Kim, Maria Magallanes-Lundback, and Dean DellaPenna
The Arabidopsis LUT1 locus encodes a member of the cytochrome P450 family that is required for carotenoid {epsilon}-ring hydroxylation activity
PNAS 2004 101: 402-407. [Abstract] [Full Text] [PDF]  

Population Biology

Aaron A. King, R. F. Costantino, J. M. Cushing, Shandelle M. Henson, Robert A. Desharnais, and Brian Dennis
Anatomy of a chaotic attractor: Subtle model-predicted patterns revealed in population data
PNAS 2004 101: 408-413; published online before print December 17 2003, 10.1073/pnas.2237266100 [Abstract] [Full Text] [PDF]  

CORRECTIONS

Correction for Camargo et al., From the Cover: The contribution of 700,000 ORF sequence tags to the definition of the human transcriptome, PNAS 2001 98:12103-12108 [Extract] [Full Text] [PDF]  

Correction for Fargione et al., Community assembly and invasion: An experimental test of neutral versus niche processes, PNAS 2003 100:8916-8920 [Extract] [Full Text] [PDF]  

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