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COMMENTARIES

Michele M. Klingbeil and Paul T. Englund

Closing the gaps in kinetoplast DNA network replication
PNAS 2004 101: 4333-4334; published online before print March 22 2004, 10.1073/pnas.0401400101 [Extract] [Full Text] [PDF]  
See companion article on page 4361

Andrew D. Miranker

Unzipping the mysteries of amyloid fiber formation
PNAS 2004 101: 4335-4336; published online before print March 22 2004, 10.1073/pnas.0401163101 [Extract] [Full Text] [PDF]  
See companion article on page 4435

Aleksij Aksimentiev and Klaus Schulten

Extending molecular modeling methodology to study insertion of membrane nanopores
PNAS 2004 101: 4337-4338; published online before print March 22 2004, 10.1073/pnas.0400739101 [Extract] [Full Text] [PDF]  
See companion article on page 4431

Douglas R. Cook

Unraveling the mystery of Nod factor signaling by a genomic approach in Medicago trunactula
PNAS 2004 101: 4339-4340; published online before print March 22 2004, 10.1073/pnas.0400961101 [Extract] [Full Text] [PDF]  
See companion article on page 4701

PHYSICAL SCIENCES

Applied Mathematics

Yaneer Bar-Yam and Irving R. Epstein

Response of complex networks to stimuli
PNAS 2004 101: 4341-4345; published online before print March 18 2004, 10.1073/pnas.0400673101 [Abstract] [Full Text] [PDF]  

Chemistry

Mari Yotsu-Yamashita, Yong H. Kim, Samuel C. Dudley, Jr., Gaurav Choudhary, Arnold Pfahnl, Yasukatsu Oshima, and John W. Daly

The structure of zetekitoxin AB, a saxitoxin analog from the Panamanian golden frog Atelopus zeteki: A potent sodium-channel blocker
PNAS 2004 101: 4346-4351; published online before print March 22 2004, 10.1073/pnas.0400368101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Mathematics

Ualbai U. Umirbaev and Jie-Tai Yu

The strong Nagata conjecture
PNAS 2004 101: 4352-4355; published online before print March 16 2004, 10.1073/pnas.0308157101 [Abstract] [Full Text] [PDF]  

SOCIAL SCIENCES

BIOLOGICAL SCIENCES

Anthropology

Charles A. Lockwood, William H. Kimbel, and John M. Lynch

Morphometrics and hominoid phylogeny: Support for a chimpanzee–human clade and differentiation among great ape subspecies
PNAS 2004 101: 4356-4360; published online before print March 22 2004, 10.1073/pnas.0306235101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Biochemistry

Victor F. Lundin, Peter C. Stirling, Juan Gomez-Reino, Jill C. Mwenifumbo, Jennifer M. Obst, José M. Valpuesta, and Michel R. Leroux

Molecular clamp mechanism of substrate binding by hydrophobic coiled-coil residues of the archaeal chaperone prefoldin
PNAS 2004 101: 4367-4372; published online before print March 19 2004, 10.1073/pnas.0306276101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Donald J. Crampton, Shenyuan Guo, Donald E. Johnson, and Charles C. Richardson

The arginine finger of bacteriophage T7 gene 4 helicase: Role in energy coupling
PNAS 2004 101: 4373-4378. [Abstract] [Full Text] [PDF] [Supporting Text]  

Alexis Gautreau, Hsin-yi H. Ho, Jiaxu Li, Hanno Steen, Steven P. Gygi, and Marc W. Kirschner

Purification and architecture of the ubiquitous Wave complex
PNAS 2004 101: 4379-4383; published online before print March 19 2004, 10.1073/pnas.0400628101 [Abstract] [Full Text] [PDF]  

Puran S. Sijwali and Philip J. Rosenthal

Gene disruption confirms a critical role for the cysteine protease falcipain-2 in hemoglobin hydrolysis by Plasmodium falciparum
PNAS 2004 101: 4384-4389; published online before print March 15 2004, 10.1073/pnas.0307720101 [Abstract] [Full Text] [PDF] [Supporting Text]  

Wei Lu, Markus Oberthür, Catherine Leimkuhler, Junhua Tao, Daniel Kahne, and Christopher T. Walsh

Characterization of a regiospecific epivancosaminyl transferase GtfA and enzymatic reconstitution of the antibiotic chloroeremomycin
PNAS 2004 101: 4390-4395; published online before print March 18 2004, 10.1073/pnas.0400277101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Nikolay Zenkin and Konstantin Severinov

The role of RNA polymerase subunit in promoter-independent initiation of transcription
PNAS 2004 101: 4396-4400; published online before print March 15 2004, 10.1073/pnas.0400886101 [Abstract] [Full Text] [PDF]  

Rami I. Aqeilan, Yuri Pekarsky, Juan J. Herrero, Alexey Palamarchuk, Jean Letofsky, Teresa Druck, Francesco Trapasso, Shuang-Yin Han, Gerry Melino, Kay Huebner, and Carlo M. Croce

Functional association between Wwox tumor suppressor protein and p73, a p53 homolog
PNAS 2004 101: 4401-4406. [Abstract] [Full Text] [PDF] [Supporting Figures]  

Jae Eun Kwak, Liaoteng Wang, Scott Ballantyne, Judith Kimble, and Marvin Wickens

Mammalian GLD-2 homologs are poly(A) polymerases
PNAS 2004 101: 4407-4412. [Abstract] [Full Text] [PDF]  

Guillaume Massé, Simon T. Belt, Steven J. Rowland, and Michel Rohmer

Isoprenoid biosynthesis in the diatoms Rhizosolenia setigera (Brightwell) and Haslea ostrearia (Simonsen)
PNAS 2004 101: 4413-4418; published online before print March 22 2004, 10.1073/pnas.0400902101 [Abstract] [Full Text] [PDF]  

Nobumoto Watanabe, Harumi Arai, Yoshifumi Nishihara, Makoto Taniguchi, Naoko Watanabe, Tony Hunter, and Hiroyuki Osada

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCF^-TrCP
PNAS 2004 101: 4419-4424; published online before print March 22 2004, 10.1073/pnas.0307700101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Biophysics

Kyung H. Choi, James M. Groarke, Dorothy C. Young, Richard J. Kuhn, Janet L. Smith, Daniel C. Pevear, and Michael G. Rossmann

The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation
PNAS 2004 101: 4425-4430; published online before print March 19 2004, 10.1073/pnas.0400660101 [Abstract] [Full Text] [PDF]  

Carlos F. Lopez, Steve O. Nielsen, Preston B. Moore, and Michael L. Klein From the Cover: Understanding nature's design for a nanosyringe PNAS 2004 101: 4431-4434; published online before print March 12 2004, 10.1073/pnas.0400352101 [Abstract] [Full Text] [PDF] [Supporting Movies]   See Commentary on page 4337

Richard A. Kammerer, Dirk Kostrewa, Jesús Zurdo, Andreas Detken, Carlos García-Echeverría, Janelle D. Green, Shirley A. Müller, Beat H. Meier, Fritz K. Winkler, Christopher M. Dobson, and Michel O. Steinmetz

Exploring amyloid formation by a de novo design
PNAS 2004 101: 4435-4440; published online before print February 26 2004, 10.1073/pnas.0306786101 [Abstract] [Full Text] [PDF] [Supporting Table]  
See Commentary on page 4335

Delphine Bichet, Yu-Fung Lin, Christian A. Ibarra, Cindy Shen Huang, B. Alexander Yi, Yuh Nung Jan, and Lily Yeh Jan

Evolving potassium channels by means of yeast selection reveals structural elements important for selectivity
PNAS 2004 101: 4441-4446; published online before print March 22 2004, 10.1073/pnas.0401195101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Miguel A. Aon, Sonia Cortassa, and Brian O'Rourke

Percolation and criticality in a mitochondrial network
PNAS 2004 101: 4447-4452; published online before print March 18 2004, 10.1073/pnas.0307156101 [Abstract] [Full Text] [PDF]  

Cell Biology

Manuel Mark, Hiromi Yoshida-Komiya, Martine Gehin, Lan Liao, Ming-Jer Tsai, Bert W. O'Malley, Pierre Chambon, and Jianming Xu

Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction
PNAS 2004 101: 4453-4458. [Abstract] [Full Text] [PDF]  

Loren Michel, Elena Diaz-Rodriguez, Gopeshwar Narayan, Eva Hernando, Vundavalli V. V. S. Murty, and Robert Benezra

Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells
PNAS 2004 101: 4459-4464; published online before print March 15 2004, 10.1073/pnas.0306069101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Taku Chibazakura, Seth G. McGrew, Jonathan A. Cooper, Hirofumi Yoshikawa, and James M. Roberts

Regulation of cyclin-dependent kinase activity during mitotic exit and maintenance of genome stability by p21, p27, and p107
PNAS 2004 101: 4465-4470; published online before print March 15 2004, 10.1073/pnas.0400655101 [Abstract] [Full Text] [PDF]  

Andrew J. Syder, Sherif M. Karam, Jason C. Mills, Joseph E. Ippolito, Habib R. Ansari, Vidya Farook, and Jeffrey I. Gordon

A transgenic mouse model of metastatic carcinoma involving transdifferentiation of a gastric epithelial lineage progenitor to a neuroendocrine phenotype
PNAS 2004 101: 4471-4476. [Abstract] [Full Text] [PDF] [Supporting Information]  

Chang-Goo Huh, Valentina M. Factor, Aránzazu Sánchez, Koichi Uchida, Elizabeth A. Conner, and Snorri S. Thorgeirsson

Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair
PNAS 2004 101: 4477-4482. [Abstract] [Full Text] [PDF] [Supporting Figures]  

Sebastian Treusch, Sarah Knuth, Susan A. Slaugenhaupt, Ehud Goldin, Barth D. Grant, and Hanna Fares

Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis
PNAS 2004 101: 4483-4488; published online before print March 15 2004, 10.1073/pnas.0400709101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Developmental Biology

Wei Liu, Jennifer Selever, Degang Wang, Mei-Fang Lu, Kelvin A. Moses, Robert J. Schwartz, and James F. Martin

Bmp4 signaling is required for outflow-tract septation and branchial-arch artery remodeling
PNAS 2004 101: 4489-4494; published online before print March 19 2004, 10.1073/pnas.0308466101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Andréa Trentin, Corinne Glavieux-Pardanaud, Nicole M. Le Douarin, and Elisabeth Dupin

Self-renewal capacity is a widespread property of various types of neural crest precursor cells
PNAS 2004 101: 4495-4500; published online before print March 15 2004, 10.1073/pnas.0400629101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Ecology

Jeffrey A. Riffell, Patrick J. Krug, and Richard K. Zimmer

The ecological and evolutionary consequences of sperm chemoattraction
PNAS 2004 101: 4501-4506; published online before print March 22 2004, 10.1073/pnas.0304594101 [Abstract] [Full Text] [PDF] [Supporting Infromation]  

Evolution

Yajuan J. Liu and Benjamin D. Hall

Body plan evolution of ascomycetes, as inferred from an RNA polymerase II phylogeny
PNAS 2004 101: 4507-4512; published online before print March 19 2004, 10.1073/pnas.0400938101 [Abstract] [Full Text] [PDF] [Supporting Information]  

M. Bakkali, T.-Y. Chen, H. C. Lee, and R. J. Redfield

Evolutionary stability of DNA uptake signal sequences in the Pasteurellaceae
PNAS 2004 101: 4513-4518; published online before print March 19 2004, 10.1073/pnas.0306366101 [Abstract] [Full Text] [PDF]  

Genetics

Kiersten A. Henderson and Scott Keeney

Tying synaptonemal complex initiation to the formation and programmed repair of DNA double-strand breaks
PNAS 2004 101: 4519-4524; published online before print March 18 2004, 10.1073/pnas.0400843101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Kristin Baetz, Lianne McHardy, Ken Gable, Tamsin Tarling, Delphine Rebérioux, Jenny Bryan, Raymond J. Andersen, Teresa Dunn, Phil Hieter, and Michel Roberge

Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action
PNAS 2004 101: 4525-4530; published online before print March 15 2004, 10.1073/pnas.0307122101 [Abstract] [Full Text] [PDF]  

Julio Licinio, Sinan Caglayan, Metin Ozata, Bulent O. Yildiz, Patricia B. de Miranda, Fiona O'Kirwan, Robert Whitby, Liyin Liang, Pinchas Cohen, Shalender Bhasin, Ronald M. Krauss, Johannes D. Veldhuis, Anthony J. Wagner, Alex M. DePaoli, Samuel M. McCann, and Ma-Li Wong

Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults
PNAS 2004 101: 4531-4536; published online before print March 9 2004, 10.1073/pnas.0308767101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Peter J. Sabo, Richard Humbert, Michael Hawrylycz, James C. Wallace, Michael O. Dorschner, Michael McArthur, and John A. Stamatoyannopoulos

Genome-wide identification of DNaseI hypersensitive sites using active chromatin sequence libraries
PNAS 2004 101: 4537-4542; published online before print March 19 2004, 10.1073/pnas.0400678101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Takeshi Imai, Reiko Takakuwa, Sandra Marchand, Emilie Dentz, Jean-Marc Bornert, Nadia Messaddeq, Olivia Wendling, Manuel Mark, Béatrice Desvergne, Walter Wahli, Pierre Chambon, and Daniel Metzger

Peroxisome proliferator-activated receptor is required in mature white and brown adipocytes for their survival in the mouse
PNAS 2004 101: 4543-4547; published online before print March 16 2004, 10.1073/pnas.0400356101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Fredrik Dahl, Johan Banér, Mats Gullberg, Maritha Mendel-Hartvig, Ulf Landegren, and Mats Nilsson

Circle-to-circle amplification for precise and sensitive DNA analysis
PNAS 2004 101: 4548-4553; published online before print March 15 2004, 10.1073/pnas.0400834101 [Abstract] [Full Text] [PDF]  

B. D. Gregory, B. E. Nickels, S. J. Garrity, E. Severinova, L. Minakhin, R. J. Bieber Urbauer, J. L. Urbauer, T. Heyduk, K. Severinov, and A. Hochschild

A regulator that inhibits transcription by targeting an intersubunit interaction of the RNA polymerase holoenzyme
PNAS 2004 101: 4554-4559; published online before print March 22 2004, 10.1073/pnas.0400923101 [Abstract] [Full Text] [PDF]  

Immunology

Frank A. W. Verreck, Tjitske de Boer, Dennis M. L. Langenberg, Marieke A. Hoeve, Matthijs Kramer, Elena Vaisberg, Robert Kastelein, Arend Kolk, René de Waal-Malefyt, and Tom H. M. Ottenhoff

Human IL-23-producing type 1 macrophages promote but IL-10-producing type 2 macrophages subvert immunity to (myco)bacteria
PNAS 2004 101: 4560-4565; published online before print March 19 2004, 10.1073/pnas.0400983101 [Abstract] [Full Text] [PDF]  

Marc Schmidt-Supprian, Jane Tian, Ethan P. Grant, Manolis Pasparakis, René Maehr, Huib Ovaa, Hidde L. Ploegh, Anthony J. Coyle, and Klaus Rajewsky

Differential dependence of CD4⁺CD25⁺ regulatory and natural killer-like T cells on signals leading to NF-B activation
PNAS 2004 101: 4566-4571; published online before print March 16 2004, 10.1073/pnas.0400885101 [Abstract] [Full Text] [PDF]  

Yufeng Peng, Yasmina Laouar, Ming O. Li, E. Allison Green, and Richard A. Flavell

TGF- regulates in vivo expansion of Foxp3-expressing CD4⁺CD25⁺ regulatory T cells responsible for protection against diabetes
PNAS 2004 101: 4572-4577; published online before print March 18 2004, 10.1073/pnas.0400810101 [Abstract] [Full Text] [PDF]  

Medical Sciences

Wen-Chien Chou, Chunfa Jie, Andrew A. Kenedy, Richard J. Jones, Michael A. Trush, and Chi V. Dang

Role of NADPH oxidase in arsenic-induced reactive oxygen species formation and cytotoxicity in myeloid leukemia cells
PNAS 2004 101: 4578-4583; published online before print March 15 2004, 10.1073/pnas.0306687101 [Abstract] [Full Text] [PDF]  

Michael R. Taylor, James B. Hurley, Heather A. Van Epps, and Susan E. Brockerhoff

A zebrafish model for pyruvate dehydrogenase deficiency: Rescue of neurological dysfunction and embryonic lethality using a ketogenic diet
PNAS 2004 101: 4584-4589; published online before print March 15 2004, 10.1073/pnas.0307074101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Linda S. Wyatt, Patricia L. Earl, Leigh Anne Eller, and Bernard Moss

Highly attenuated smallpox vaccine protects mice with and without immune deficiencies against pathogenic vaccinia virus challenge
PNAS 2004 101: 4590-4595; published online before print March 11 2004, 10.1073/pnas.0401165101 [Abstract] [Full Text] [PDF]  

Microbiology

Adel M. Talaat, Rick Lyons, Susan T. Howard, and Stephen Albert Johnston

The temporal expression profile of Mycobacterium tuberculosis infection in mice
PNAS 2004 101: 4602-4607; published online before print March 18 2004, 10.1073/pnas.0306023101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Kenolisa C. Onwueme, Julian A. Ferreras, John Buglino, Christopher D. Lima, and Luis E. N. Quadri

Mycobacterial polyketide-associated proteins are acyltransferases: Proof of principle with Mycobacterium tuberculosis PapA5
PNAS 2004 101: 4608-4613; published online before print March 18 2004, 10.1073/pnas.0306928101 [Abstract] [Full Text] [PDF] [Supporting Text]  

Erik Haghjoo and Jorge E. Galán

Salmonella typhi encodes a functional cytolethal distending toxin that is delivered into host cells by a bacterial-internalization pathway
PNAS 2004 101: 4614-4619. [Abstract] [Full Text] [PDF] [Supporting Information]  

Mikhail N. Matrosovich, Tatyana Y. Matrosovich, Thomas Gray, Noel A. Roberts, and Hans-Dieter Klenk

Human and avian influenza viruses target different cell types in cultures of human airway epithelium
PNAS 2004 101: 4620-4624; published online before print March 15 2004, 10.1073/pnas.0308001101 [Abstract] [Full Text] [PDF]  

Christopher J. Farrell, Jae Myun Lee, Eui-Cheol Shin, Marek Cebrat, Philip A. Cole, and S. Diane Hayward

Inhibition of Epstein-Barr virus-induced growth proliferation by a nuclear antigen EBNA2-TAT peptide
PNAS 2004 101: 4625-4630; published online before print March 19 2004, 10.1073/pnas.0306482101 [Abstract] [Full Text] [PDF]  

P. Buford Price and Todd Sowers

Temperature dependence of metabolic rates for microbial growth, maintenance, and survival
PNAS 2004 101: 4631-4636. [Abstract] [Full Text] [PDF]  

Neuroscience

Michael D. Greicius, Gaurav Srivastava, Allan L. Reiss, and Vinod Menon

Default-mode network activity distinguishes Alzheimer's disease from healthy aging: Evidence from functional MRI
PNAS 2004 101: 4637-4642; published online before print March 15 2004, 10.1073/pnas.0308627101 [Abstract] [Full Text] [PDF] [Supporting Tables]  

Christopher M. Taylor, Cecilia B. Marta, Robert J. Claycomb, David K. Han, Matthew N. Rasband, Timothy Coetzee, and Steven E. Pfeiffer

Proteomic mapping provides powerful insights into functional myelin biology
PNAS 2004 101: 4643-4648; published online before print March 19 2004, 10.1073/pnas.0400922101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Michihiro Mieda, Jon T. Willie, Junko Hara, Christopher M. Sinton, Takeshi Sakurai, and Masashi Yanagisawa From The Cover: Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice PNAS 2004 101: 4649-4654; published online before print March 16 2004, 10.1073/pnas.0400590101 [Abstract] [Full Text] [PDF] [Supporting Figure]

Nicolas Schweighofer, Kenji Doya, Hidekazu Fukai, Jean Vianney Chiron, Tetsuya Furukawa, and Mitsuo Kawato

Chaos may enhance information transmission in the inferior olive
PNAS 2004 101: 4655-4660; published online before print March 22 2004, 10.1073/pnas.0305966101 [Abstract] [Full Text] [PDF]  

Qian Gao, Michael J. Wolfgang, Susanne Neschen, Katsutaro Morino, Tamas L. Horvath, Gerald I. Shulman, and Xin-Yuan Fu

Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation
PNAS 2004 101: 4661-4666; published online before print March 22 2004, 10.1073/pnas.0303992101 [Abstract] [Full Text] [PDF]  

K. Matthew Lattal and Ted Abel

Behavioral impairments caused by injections of the protein synthesis inhibitor anisomycin after contextual retrieval reverse with time
PNAS 2004 101: 4667-4672; published online before print March 19 2004, 10.1073/pnas.0306546101 [Abstract] [Full Text] [PDF] [Supporting Text]  

Pharmacology

Mari Yotsu-Yamashita, Yong H. Kim, Samuel C. Dudley, Jr., Gaurav Choudhary, Arnold Pfahnl, Yasukatsu Oshima, and John W. Daly

The structure of zetekitoxin AB, a saxitoxin analog from the Panamanian golden frog Atelopus zeteki: A potent sodium-channel blocker
PNAS 2004 101: 4346-4351; published online before print March 22 2004, 10.1073/pnas.0400368101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

S. J. Briddon, R. J. Middleton, Y. Cordeaux, F. M. Flavin, J. A. Weinstein, M. W. George, B. Kellam, and S. J. Hill

Quantitative analysis of the formation and diffusion of A₁-adenosine receptor-antagonist complexes in single living cells
PNAS 2004 101: 4673-4678; published online before print March 16 2004, 10.1073/pnas.0400420101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Physiology

Yuxiang Sun, Pei Wang, Hui Zheng, and Roy G. Smith

Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor
PNAS 2004 101: 4679-4684; published online before print March 18 2004, 10.1073/pnas.0305930101 [Abstract] [Full Text] [PDF]  

Laura T. Goldsmith, Gerson Weiss, Smita Palejwala, Tony M. Plant, Andrea Wojtczuk, W. Clark Lambert, Nael Ammur, Debra Heller, Joan H. Skurnick, Dean Edwards, and Donna M. Cole

Relaxin regulation of endometrial structure and function in the rhesus monkey
PNAS 2004 101: 4685-4689; published online before print March 19 2004, 10.1073/pnas.0400776101 [Abstract] [Full Text] [PDF]  

Kozue Yamauchi, Tatemitsu Rai, Katsuki Kobayashi, Eisei Sohara, Tatsunori Suzuki, Tomohiro Itoh, Shin Suda, Atsushi Hayama, Sei Sasaki, and Shinichi Uchida

Disease-causing mutant WNK4 increases paracellular chloride permeability and phosphorylates claudins
PNAS 2004 101: 4690-4694; published online before print March 19 2004, 10.1073/pnas.0306924101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

B. G. Challis, A. P. Coll, G. S. H. Yeo, S. B. Pinnock, S. L. Dickson, R. R. Thresher, J. Dixon, D. Zahn, J. J. Rochford, A. White, R. L. Oliver, G. Millington, S. A. Aparicio, W. H. Colledge, A. P. Russ, M. B. Carlton, and S. O'Rahilly

Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY_3-36
PNAS 2004 101: 4695-4700; published online before print March 15 2004, 10.1073/pnas.0306931101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Plant Biology

Pierre Broun, Patricia Poindexter, Erin Osborne, Cai-Zhong Jiang, and José Luis Riechmann

WIN1, a transcriptional activator of epidermal wax accumulation in Arabidopsis
PNAS 2004 101: 4706-4711; published online before print March 22 2004, 10.1073/pnas.0305574101 [Abstract] [Full Text] [PDF] [Supporting Information]  

John R. Stinchcombe, Cynthia Weinig, Mark Ungerer, Kenneth M. Olsen, Charlotte Mays, Solveig S. Halldorsdottir, Michael D. Purugganan, and Johanna Schmitt

A latitudinal cline in flowering time in Arabidopsis thaliana modulated by the flowering time gene FRIGIDA
PNAS 2004 101: 4712-4717; published online before print March 19 2004, 10.1073/pnas.0306401101 [Abstract] [Full Text] [PDF] [Supporting Information]  

CORRECTIONS

Correction for Laragione et al., Redox regulation of surface protein thiols: Identification of integrin -4 as a molecular target by using redox proteomics, PNAS 2003 100:14737-14741 [Extract] [Full Text] [PDF]  

Correction for Ziegelbauer et al., Myc-interacting protein 1 target gene profile: A link to microtubules, extracellular signal-regulated kinase, and cell growth, PNAS 2004 101:458-463 [Extract] [Full Text] [PDF]  

Correction for Boon et al., DNA-mediated charge transport for DNA repair, PNAS 2003 100:12543-12547 [Extract] [Full Text] [PDF]  

Correction for Parikh et al., A strabismus susceptibility locus on chromosome 7p, PNAS 2003 100:12283-12288 [Extract] [Full Text] [PDF]