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COMMENTARIES

Michel Tibayrenc

A molecular biology approach to tuberculosis
PNAS 2004 101: 4721-4722; published online before print March 29 2004, 10.1073/pnas.0400877101 [Extract] [Full Text] [PDF]  
See companion article on page 4865
See companion article on page 4871

Daniel Medina

Stromal fibroblasts influence human mammary epithelial cell morphogenesis
PNAS 2004 101: 4723-4724; published online before print March 29 2004, 10.1073/pnas.0401376101 [Extract] [Full Text] [PDF]  
See companion article on page 4966

PHYSICAL SCIENCES

Applied Mathematics

Andrew J. Majda and Joseph A. Biello

A multiscale model for tropical intraseasonal oscillations
PNAS 2004 101: 4736-4741; published online before print March 24 2004, 10.1073/pnas.0401034101 [Abstract] [Full Text] [PDF]  

Physics

SOCIAL SCIENCES

Economic Sciences

Prajit K. Dutta and Roy Radner

Self-enforcing climate-change treaties
PNAS 2004 101: 5174-5179; published online before print March 29 2004, 10.1073/pnas.0400489101 [Abstract] [Full Text] [PDF]  

BIOLOGICAL SCIENCES

Anthropology

Thierry Wirth, Xiaoyan Wang, Bodo Linz, Richard P. Novick, J. Koji Lum, Martin Blaser, Giovanna Morelli, Daniel Falush, and Mark Achtman

Distinguishing human ethnic groups by means of sequences from Helicobacter pylori: Lessons from Ladakh
PNAS 2004 101: 4746-4751; published online before print March 29 2004, 10.1073/pnas.0306629101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Biochemistry

Qinghai Zhang, Evan T. Powers, Jorge Nieva, Mary E. Huff, Maria A. Dendle, Jan Bieschke, Charles G. Glabe, Albert Eschenmoser, Paul Wentworth, Jr., Richard A. Lerner, and Jeffery W. Kelly

Metabolite-initiated protein misfolding may trigger Alzheimer's disease
PNAS 2004 101: 4752-4757; published online before print March 19 2004, 10.1073/pnas.0400924101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Paul L. Shaffer, Arif Jivan, D. Eric Dollins, Frank Claessens, and Daniel T. Gewirth

Structural basis of androgen receptor binding to selective androgen response elements
PNAS 2004 101: 4758-4763; published online before print March 22 2004, 10.1073/pnas.0401123101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Daniel Clayton, George Shapovalov, Joshua A. Maurer, Dennis A. Dougherty, Henry A. Lester, and Gerd G. Kochendoerfer

Total chemical synthesis and electrophysiological characterization of mechanosensitive channels from Escherichia coli and Mycobacterium tuberculosis
PNAS 2004 101: 4764-4769; published online before print March 23 2004, 10.1073/pnas.0305693101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Tohru Yamada, Yoshinori Hiraoka, Masateru Ikehata, Kazuhide Kimbara, Benjamin S. Avner, Tapas K. Das Gupta, and Ananda M. Chakrabarty

Apoptosis or growth arrest: Modulation of tumor suppressor p53's specificity by bacterial redox protein azurin
PNAS 2004 101: 4770-4775; published online before print March 24 2004, 10.1073/pnas.0400899101 [Abstract] [Full Text] [PDF]  

Biophysics

Andrey Revyakin, Richard H. Ebright, and Terence R. Strick

Promoter unwinding and promoter clearance by RNA polymerase: Detection by single-molecule DNA nanomanipulation
PNAS 2004 101: 4776-4780; published online before print March 22 2004, 10.1073/pnas.0307241101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Fangting Li, Tao Long, Ying Lu, Qi Ouyang, and Chao Tang

The yeast cell-cycle network is robustly designed
PNAS 2004 101: 4781-4786; published online before print March 22 2004, 10.1073/pnas.0305937101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Amel Bahloul, Guillaume Chevreux, Amber L. Wells, Davy Martin, Jocelyn Nolt, Zhaohui Yang, Li-Qiong Chen, Noëlle Potier, Alain Van Dorsselaer, Steve Rosenfeld, Anne Houdusse, and H. Lee Sweeney

The unique insert in myosin VI is a structural calcium–calmodulin binding site
PNAS 2004 101: 4787-4792; published online before print March 22 2004, 10.1073/pnas.0306892101 [Abstract] [Full Text] [PDF]  

Bertil Halle

Biomolecular cryocrystallography: Structural changes during flash-cooling
PNAS 2004 101: 4793-4798; published online before print March 29 2004, 10.1073/pnas.0308315101 [Abstract] [Full Text] [PDF]  

Marius Schmidt, Reinhard Pahl, Vukica Srajer, Spencer Anderson, Zhong Ren, Hyotcherl Ihee, Sudarshan Rajagopal, and Keith Moffat

Protein kinetics: Structures of intermediates and reaction mechanism from time-resolved x-ray data
PNAS 2004 101: 4799-4804; published online before print March 23 2004, 10.1073/pnas.0305983101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Sapar M. Saparov and Peter Pohl

Beyond the diffusion limit: Water flow through the empty bacterial potassium channel
PNAS 2004 101: 4805-4809; published online before print March 19 2004, 10.1073/pnas.0308309101 [Abstract] [Full Text] [PDF]  

Cell Biology

Fangting Li, Tao Long, Ying Lu, Qi Ouyang, and Chao Tang

The yeast cell-cycle network is robustly designed
PNAS 2004 101: 4781-4786; published online before print March 22 2004, 10.1073/pnas.0305937101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Svetlana Deryusheva and Joseph G. Gall

Dynamics of coilin in Cajal bodies of the Xenopus germinal vesicle
PNAS 2004 101: 4810-4814; published online before print March 24 2004, 10.1073/pnas.0401106101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Masayoshi Fukasawa, Oleg Varlamov, William S. Eng, Thomas H. Söllner, and James E. Rothman

Localization and activity of the SNARE Ykt6 determined by its regulatory domain and palmitoylation
PNAS 2004 101: 4815-4820; published online before print March 24 2004, 10.1073/pnas.0401183101 [Abstract] [Full Text] [PDF]  

Akrit Sodhi, Silvia Montaner, Vyomesh Patel, José Javier Gómez-Román, Yi Li, Edward A. Sausville, Earl T. Sawai, and J. Silvio Gutkind

Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor
PNAS 2004 101: 4821-4826; published online before print March 26 2004, 10.1073/pnas.0400835101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Damien Derouet, François Rousseau, Fabienne Alfonsi, Josy Froger, Jacques Hermann, Fabien Barbier, David Perret, Caroline Diveu, Catherine Guillet, Laurence Preisser, Agnès Dumont, Maud Barbado, Alain Morel, Odile deLapeyrière, Hugues Gascan, and Sylvie Chevalier

Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor
PNAS 2004 101: 4827-4832; published online before print March 29 2004, 10.1073/pnas.0306178101 [Abstract] [Full Text] [PDF]  

Shouwen Wang, Xingbin Ai, Stephen D. Freeman, Mary E. Pownall, Qun Lu, Daniel S. Kessler, and Charles P. Emerson, Jr.

QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis
PNAS 2004 101: 4833-4838; published online before print March 29 2004, 10.1073/pnas.0401028101 [Abstract] [Full Text] [PDF]  

Developmental Biology

Enrico Coen, Anne-Gaëlle Rolland-Lagan, Mark Matthews, J. Andrew Bangham, and Przemyslaw Prusinkiewicz Inaugural Article by a Recently Elected Academy Member: Inaugural Article: The genetics of geometry PNAS 2004 101: 4728-4735; published online before print February 11 2004, 10.1073/pnas.0306308101 [Abstract] [Full Text] [PDF]

Biswajit Das and Donald D. Brown

Controlling transgene expression to study Xenopus laevis metamorphosis
PNAS 2004 101: 4839-4842; published online before print March 26 2004, 10.1073/pnas.0401011101 [Abstract] [Full Text] [PDF]  

Sophie Creuzet, Bernadette Schuler, Gérard Couly, and Nicole M. Le Douarin From the Cover: Reciprocal relationships between Fgf8 and neural crest cells in facial and forebrain development PNAS 2004 101: 4843-4847; published online before print March 23 2004, 10.1073/pnas.0400869101 [Abstract] [Full Text] [PDF]

Xu Huang, Yuqing Dong, and Jindong Zhao

HetR homodimer is a DNA-binding protein required for heterocyst differentiation, and the DNA-binding activity is inhibited by PatS
PNAS 2004 101: 4848-4853; published online before print March 29 2004, 10.1073/pnas.0400429101 [Abstract] [Full Text] [PDF]  

Ecology

K. Ullas Karanth, James D. Nichols, N. Samba Kumar, William A. Link, and James E. Hines

Tigers and their prey: Predicting carnivore densities from prey abundance
PNAS 2004 101: 4854-4858; published online before print March 23 2004, 10.1073/pnas.0306210101 [Abstract] [Full Text] [PDF]  

Ute Wittstock, Niels Agerbirk, Einar J. Stauber, Carl Erik Olsen, Michael Hippler, Thomas Mitchell-Olds, Jonathan Gershenzon, and Heiko Vogel

Successful herbivore attack due to metabolic diversion of a plant chemical defense
PNAS 2004 101: 4859-4864; published online before print March 29 2004, 10.1073/pnas.0308007101 [Abstract] [Full Text] [PDF]  

Evolution

Aaron E. Hirsh, Anthony G. Tsolaki, Kathryn DeRiemer, Marcus W. Feldman, and Peter M. Small From the Cover: Stable association between strains of Mycobacterium tuberculosis and their human host populations PNAS 2004 101: 4871-4876; published online before print March 23 2004, 10.1073/pnas.0305627101 [Abstract] [Full Text] [PDF] [Supporting Figures]   See Commentary on page 4721

Najmus S. Mahfooz, Hua Li, and Aleksandar Popadic From the Cover: Differential expression patterns of the hox gene are associated with differential growth of insect hind legs PNAS 2004 101: 4877-4882; published online before print March 23 2004, 10.1073/pnas.0401216101 [Abstract] [Full Text] [PDF]

Margarita Ramos, Duncan J. Irschick, and Terry E. Christenson

Overcoming an evolutionary conflict: Removal of a reproductive organ greatly increases locomotor performance
PNAS 2004 101: 4883-4887; published online before print March 19 2004, 10.1073/pnas.0400324101 [Abstract] [Full Text] [PDF]  

Martin Hasselmann and Martin Beye

Signatures of selection among sex-determining alleles of the honey bee
PNAS 2004 101: 4888-4893; published online before print March 29 2004, 10.1073/pnas.0307147101 [Abstract] [Full Text] [PDF]  

Robert Belshaw, Vini Pereira, Aris Katzourakis, Gillian Talbot, Jan Paces, Austin Burt, and Michael Tristem

Long-term reinfection of the human genome by endogenous retroviruses
PNAS 2004 101: 4894-4899; published online before print March 25 2004, 10.1073/pnas.0307800101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Henner Brinkmann, Byrappa Venkatesh, Sydney Brenner, and Axel Meyer

Nuclear protein-coding genes support lungfish and not the coelacanth as the closest living relatives of land vertebrates
PNAS 2004 101: 4900-4905; published online before print March 22 2004, 10.1073/pnas.0400609101 [Abstract] [Full Text] [PDF]  

Genetics

Vladimir I. Kashuba, Jingfeng Li, Fuli Wang, Vera N. Senchenko, Alexey Protopopov, Alena Malyukova, Alexey S. Kutsenko, Elena Kadyrova, Veronika I. Zabarovska, Olga V. Muravenko, Alexander V. Zelenin, Lev L. Kisselev, Igor Kuzmin, John D. Minna, Gösta Winberg, Ingemar Ernberg, Eleonora Braga, Michael I. Lerman, George Klein, and Eugene R. Zabarovsky

RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies
PNAS 2004 101: 4906-4911; published online before print March 29 2004, 10.1073/pnas.0401238101 [Abstract] [Full Text] [PDF]  

Sebastian Schuck, Aki Manninen, Masanori Honsho, Joachim Füllekrug, and Kai Simons

Generation of single and double knockdowns in polarized epithelial cells by retrovirus-mediated RNA interference
PNAS 2004 101: 4912-4917; published online before print March 29 2004, 10.1073/pnas.0401285101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Richard D. Palmiter

Protection against zinc toxicity by metallothionein and zinc transporter 1
PNAS 2004 101: 4918-4923; published online before print March 23 2004, 10.1073/pnas.0401022101 [Abstract] [Full Text] [PDF]  

L. H. Castilla, P. Perrat, N. J. Martinez, S. F. Landrette, R. Keys, S. Oikemus, J. Flanegan, S. Heilman, L. Garrett, A. Dutra, S. Anderson, G. A. Pihan, L. Wolff, and P. P. Liu

Identification of genes that synergize with Cbfb-MYH11 in the pathogenesis of acute myeloid leukemia
PNAS 2004 101: 4924-4929; published online before print March 24 2004, 10.1073/pnas.0400930101 [Abstract] [Full Text] [PDF] [Supporting Tables]  

Timothy E. Baroni, Ting Wang, Hua Qian, Lawrence R. Dearth, Lan N. Truong, Jue Zeng, Alec E. Denes, Stephanie W. Chen, and Rainer K. Brachmann

A global suppressor motif for p53 cancer mutants
PNAS 2004 101: 4930-4935; published online before print March 22 2004, 10.1073/pnas.0401162101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Immunology

Yina H. Huang, Dongling Li, Astar Winoto, and Ellen A. Robey

Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals
PNAS 2004 101: 4936-4941; published online before print March 25 2004, 10.1073/pnas.0401133101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Katherine Kedzierska, Stephen J. Turner, and Peter C. Doherty

Conserved T cell receptor usage in primary and recall responses to an immunodominant influenza virus nucleoprotein epitope
PNAS 2004 101: 4942-4947; published online before print March 22 2004, 10.1073/pnas.0401279101 [Abstract] [Full Text] [PDF]  

Medical Sciences

Zsuzsanna Callaerts-Vegh, Kenda L. J. Evans, Noornabi Dudekula, Donald Cuba, Brian J. Knoll, Patrick F. K. Callaerts, Heather Giles, Felix R. Shardonofsky, and Richard A. Bond

Effects of acute and chronic administration of -adrenoceptor ligands on airway function in a murine model of asthma
PNAS 2004 101: 4948-4953. [Abstract] [Full Text] [PDF] [Supporting Figure]  

Nita S. Agar, Gary M. Halliday, Ross StC. Barnetson, Honnavara N. Ananthaswamy, Mark Wheeler, and Alexandra M. Jones

The basal layer in human squamous tumors harbors more UVA than UVB fingerprint mutations: A role for UVA in human skin carcinogenesis
PNAS 2004 101: 4954-4959; published online before print March 23 2004, 10.1073/pnas.0401141101 [Abstract] [Full Text] [PDF]  

Harutaka Katano, Lesley Pesnicak, and Jeffrey I. Cohen

Simvastatin induces apoptosis of Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines and delays development of EBV lymphomas
PNAS 2004 101: 4960-4965; published online before print March 23 2004, 10.1073/pnas.0305149101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Charlotte Kuperwasser, Tony Chavarria, Min Wu, Greg Magrane, Joe W. Gray, Loucinda Carey, Andrea Richardson, and Robert A. Weinberg From The Cover: Reconstruction of functionally normal and malignant human breast tissues in mice PNAS 2004 101: 4966-4971; published online before print March 29 2004, 10.1073/pnas.0401064101 [Abstract] [Full Text] [PDF] [Supporting Information]   See Commentary on page 4723

Maria H. Lind, Björn Rozell, Robert P. A. Wallin, Max van Hogerlinden, Hans-Gustaf Ljunggren, Rune Toftgård, and Inderpreet Sur

Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-B inhibition
PNAS 2004 101: 4972-4977; published online before print March 25 2004, 10.1073/pnas.0307106101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Jennifer C. Condon, Pancharatnam Jeyasuria, Julie M. Faust, and Carole R. Mendelson

Surfactant protein secreted by the maturing mouse fetal lung acts as a hormone that signals the initiation of parturition
PNAS 2004 101: 4978-4983; published online before print March 25 2004, 10.1073/pnas.0401124101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Eran R. Andrechek, William R. Hardy, Michael A. Laing, and William J. Muller

Germ-line expression of an oncogenic erbB2 allele confers resistance to erbB2-induced mammary tumorigenesis
PNAS 2004 101: 4984-4989; published online before print March 29 2004, 10.1073/pnas.0306802101 [Abstract] [Full Text] [PDF]  

Shilin Yang, Yi Yang, John Raycraft, Hongtao Zhang, Sandra Kanan, Yajun Guo, Ze'ev Ronai, Ingegerd Hellstrom, and Karl Erik Hellstrom

Melanoma cells transfected to express CD83 induce antitumor immunity that can be increased by also engaging CD137
PNAS 2004 101: 4990-4995; published online before print March 29 2004, 10.1073/pnas.0400880101 [Abstract] [Full Text] [PDF]  

Judit E. Horvath, Gabor L. Toller, Andrew V. Schally, Ana-Maria Bajo, and Kate Groot

Effect of long-term treatment with low doses of the LHRH antagonist Cetrorelix on pituitary receptors for LHRH and gonadal axis in male and female rats
PNAS 2004 101: 4996-5001; published online before print March 24 2004, 10.1073/pnas.0400605101 [Abstract] [Full Text] [PDF]  

Alex Duval, Martine Raphael, Caroline Brennetot, Helene Poirel, Olivier Buhard, Alban Aubry, Antoine Martin, Amor Krimi, Veronique Leblond, Jean Gabarre, Frederic Davi, Frederic Charlotte, Francoise Berger, Gianluca Gaidano, Daniela Capello, Danielle Canioni, Dominique Bordessoule, Jean Feuillard, Philippe Gaulard, Marie Helene Delfau, Sophie Ferlicot, Virginie Eclache, Sophie Prevot, Catherine Guettier, Pascale Cornillet Lefevre, Francoise Adotti, and Richard Hamelin

The mutator pathway is a feature of immunodeficiency-related lymphomas
PNAS 2004 101: 5002-5007; published online before print March 26 2004, 10.1073/pnas.0400945101 [Abstract] [Full Text] [PDF]  

Donald C. Malins, Katie M. Anderson, Nayak L. Polissar, Gary K. Ostrander, Edward T. Knobbe, Virginia M. Green, Naomi K. Gilman, and Jerry L. Spivak

Models of granulocyte DNA structure are highly predictive of myelodysplastic syndrome
PNAS 2004 101: 5008-5011; published online before print March 29 2004, 10.1073/pnas.0400838101 [Abstract] [Full Text] [PDF]  

Microbiology

Gail P. Ferguson, Anup Datta, John Baumgartner, R. Martin Roop, II, Russ W. Carlson, and Graham C. Walker

Similarity to peroxisomal-membrane protein family reveals that Sinorhizobium and Brucella BacA affect lipid-A fatty acids
PNAS 2004 101: 5012-5017; published online before print March 24 2004, 10.1073/pnas.0307137101 [Abstract] [Full Text] [PDF]  

Susan M. Butler and Andrew Camilli

Both chemotaxis and net motility greatly influence the infectivity of Vibrio cholerae
PNAS 2004 101: 5018-5023; published online before print March 22 2004, 10.1073/pnas.0308052101 [Abstract] [Full Text] [PDF]  

Sören Schreiber, Manuela Konradt, Claudia Groll, Peter Scheid, Guido Hanauer, Hans-Otto Werling, Christine Josenhans, and Sebastian Suerbaum

The spatial orientation of Helicobacter pylori in the gastric mucus
PNAS 2004 101: 5024-5029; published online before print March 25 2004, 10.1073/pnas.0308386101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Valera V. Peremyslov, Igor A. Andreev, Alexey I. Prokhnevsky, George H. Duncan, Michael E. Taliansky, and Valerian V. Dolja

Complex molecular architecture of beet yellows virus particles
PNAS 2004 101: 5030-5035; published online before print March 25 2004, 10.1073/pnas.0400303101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Zhihai Si, Navid Madani, Jason M. Cox, Jason J. Chruma, Jeffrey C. Klein, Arne Schön, Ngoc Phan, Liping Wang, Alyssa C. Biorn, Simon Cocklin, Irwin Chaiken, Ernesto Freire, Amos B. Smith, III, and Joseph G. Sodroski

Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins
PNAS 2004 101: 5036-5041; published online before print March 29 2004, 10.1073/pnas.0307953101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Thomas R. Kozel, William J. Murphy, Suzanne Brandt, Bruce R. Blazar, Julie A. Lovchik, Peter Thorkildson, Ann Percival, and C. Rick Lyons

mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia
PNAS 2004 101: 5042-5047; published online before print March 29 2004, 10.1073/pnas.0401351101 [Abstract] [Full Text] [PDF]  

Hao Chen, Masaki Fujita, Qinghua Feng, Jon Clardy, and Gerald R. Fink

Tyrosol is a quorum-sensing molecule in Candida albicans
PNAS 2004 101: 5048-5052; published online before print March 29 2004, 10.1073/pnas.0401416101 [Abstract] [Full Text] [PDF]  

Neuroscience

S. Vanhatalo, J. M. Palva, M. D. Holmes, J. W. Miller, J. Voipio, and K. Kaila

Infraslow oscillations modulate excitability and interictal epileptic activity in the human cortex during sleep
PNAS 2004 101: 5053-5057; published online before print March 24 2004, 10.1073/pnas.0305375101 [Abstract] [Full Text] [PDF] [Supporting Information]  

R. Jason Pitts, A. Nicole Fox, and Laurence J. Zwiebel

A highly conserved candidate chemoreceptor expressed in both olfactory and gustatory tissues in the malaria vector Anopheles gambiae
PNAS 2004 101: 5058-5063; published online before print March 22 2004, 10.1073/pnas.0308146101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

G. T. Prusky, R. M. Douglas, L. Nelson, A. Shabanpoor, and R. J. Sutherland

Visual memory task for rats reveals an essential role for hippocampus and perirhinal cortex
PNAS 2004 101: 5064-5068; published online before print March 29 2004, 10.1073/pnas.0308528101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Stefano Gustincich, Massimo Contini, Manuela Gariboldi, Michelino Puopolo, Koji Kadota, Hidemasa Bono, Julianna LeMieux, Pamela Walsh, Piero Carninci, Yoshihide Hayashizaki, Yasushi Okazaki, and Elio Raviola

Gene discovery in genetically labeled single dopaminergic neurons of the retina
PNAS 2004 101: 5069-5074; published online before print March 26 2004, 10.1073/pnas.0400913101 [Abstract] [Full Text] [PDF]  

Katerina Akassoglou, Brian Malester, Jixiang Xu, Lino Tessarollo, Jack Rosenbluth, and Moses V. Chao

Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration
PNAS 2004 101: 5075-5080; published online before print March 29 2004, 10.1073/pnas.0401030101 [Abstract] [Full Text] [PDF]  

Haishan Yao, Yaosong Shen, and Yang Dan

Intracortical mechanism of stimulus-timing-dependent plasticity in visual cortical orientation tuning
PNAS 2004 101: 5081-5086; published online before print March 24 2004, 10.1073/pnas.0302510101 [Abstract] [Full Text] [PDF]  

Hyo Chol Ha

Defective transcription factor activation for proinflammatory gene expression in poly(ADP-ribose) polymerase 1-deficient glia
PNAS 2004 101: 5087-5092; published online before print March 23 2004, 10.1073/pnas.0306895101 [Abstract] [Full Text] [PDF]  

Yun Wang and Patricia S. Goldman-Rakic

D2 receptor regulation of synaptic burst firing in prefrontal cortical pyramidal neurons
PNAS 2004 101: 5093-5098; published online before print March 29 2004, 10.1073/pnas.0400954101 [Abstract] [Full Text] [PDF]  

Jean-Martin Beaulieu, Tatyana D. Sotnikova, Wei-Dong Yao, Lisa Kockeritz, James R. Woodgett, Raul R. Gainetdinov, and Marc G. Caron

Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade
PNAS 2004 101: 5099-5104; published online before print March 24 2004, 10.1073/pnas.0307921101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Caroline R. Elliott-Hunt, Barnaby Marsh, Andrea Bacon, Robert Pope, Penny Vanderplank, and David Wynick

Galanin acts as a neuroprotective factor to the hippocampus
PNAS 2004 101: 5105-5110; published online before print March 23 2004, 10.1073/pnas.0304823101 [Abstract] [Full Text] [PDF]  

James Crandall, Yasuo Sakai, Jinghua Zhang, Omanand Koul, Yann Mineur, Wim E. Crusio, and Peter McCaffery

13-cis-retinoic acid suppresses hippocampal cell division and hippocampal-dependent learning in mice
PNAS 2004 101: 5111-5116; published online before print March 29 2004, 10.1073/pnas.0306336101 [Abstract] [Full Text] [PDF]  

Anat Biegon, Pamela A. Fry, Charles M. Paden, Alexander Alexandrovich, Jeanna Tsenter, and Esther Shohami

Dynamic changes in N-methyl-D-aspartate receptors after closed head injury in mice: Implications for treatment of neurological and cognitive deficits
PNAS 2004 101: 5117-5122; published online before print March 24 2004, 10.1073/pnas.0305741101 [Abstract] [Full Text] [PDF] [Supporting Information] [Online Correction to Supporting Materials and Methods]  

Ingrid van Welie, Johannes A. van Hooft, and Wytse J. Wadman

Homeostatic scaling of neuronal excitability by synaptic modulation of somatic hyperpolarization-activated I_h channels
PNAS 2004 101: 5123-5128; published online before print March 29 2004, 10.1073/pnas.0307711101 [Abstract] [Full Text] [PDF]  

Pharmacology

Christa Hegele-Hartung, Philip Siebel, Olaf Peters, Dirk Kosemund, Gerd Müller, Alexander Hillisch, Alexander Walter, Jörn Kraetzschmar, and Karl-Heinrich Fritzemeier

Impact of isotype-selective estrogen receptor agonists on ovarian function
PNAS 2004 101: 5129-5134; published online before print March 22 2004, 10.1073/pnas.0306720101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Ivone Gomes, Achla Gupta, Julija Filipovska, Hazel H. Szeto, John E. Pintar, and Lakshmi A. Devi

A role for heterodimerization of µ and opiate receptors in enhancing morphine analgesia
PNAS 2004 101: 5135-5139; published online before print March 24 2004, 10.1073/pnas.0307601101 [Abstract] [Full Text] [PDF]  

Physiology

Melita M. Dvorak, Ashia Siddiqua, Donald T. Ward, D. Howard Carter, Sarah L. Dallas, Edward F. Nemeth, and Daniela Riccardi

Physiological changes in extracellular calcium concentration directly control osteoblast function in the absence of calciotropic hormones
PNAS 2004 101: 5140-5145; published online before print March 29 2004, 10.1073/pnas.0306141101 [Abstract] [Full Text] [PDF]  

Plant Biology

Kristiina Himanen, Marnik Vuylsteke, Steffen Vanneste, Steven Vercruysse, Elodie Boucheron, Philippe Alard, Dominique Chriqui, Marc Van Montagu, Dirk Inzé, and Tom Beeckman

Transcript profiling of early lateral root initiation
PNAS 2004 101: 5146-5151; published online before print March 29 2004, 10.1073/pnas.0308702101 [Abstract] [Full Text] [PDF]  

Aardra Kachroo, Srivathsa C. Venugopal, Ludmila Lapchyk, Deane Falcone, David Hildebrand, and Pradeep Kachroo

Oleic acid levels regulated by glycerolipid metabolism modulate defense gene expression in Arabidopsis
PNAS 2004 101: 5152-5157; published online before print March 25 2004, 10.1073/pnas.0401315101 [Abstract] [Full Text] [PDF]  

Tahzeeba Hossain, Irwin Rosenberg, Jacob Selhub, Ganesh Kishore, Roger Beachy, and Karel Schubert

Enhancement of folates in plants through metabolic engineering
PNAS 2004 101: 5158-5163; published online before print March 24 2004, 10.1073/pnas.0401342101 [Abstract] [Full Text] [PDF]  

Yumin Tao, Praveen K. Rao, Saikat Bhattacharjee, and Stanton B. Gelvin

Expression of plant protein phosphatase 2C interferes with nuclear import of the Agrobacterium T-complex protein VirD2
PNAS 2004 101: 5164-5169; published online before print March 26 2004, 10.1073/pnas.0300084101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Psychology

Sherif Shady, Donald I. A. MacLeod, and Heidi S. Fisher

Adaptation from invisible flicker
PNAS 2004 101: 5170-5173; published online before print March 29 2004, 10.1073/pnas.0303452101 [Abstract] [Full Text] [PDF]  

CORRECTIONS

Correction for Korlach et al., Spontaneous nucleotide exchange in low molecular weight GTPases by fluorescently labeled -phosphate-linked GTP analogs, PNAS 2004 101:2800-2805 [Extract] [Full Text] [PDF]  

Correction for Esposito et al., Mice deficient for soluble adenylyl cyclase are infertile because of a severe sperm-motility defect, PNAS 2004 101:2993-2998 [Extract] [Full Text] [PDF]  

Correction for Stiles et al., Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity, PNAS 2004 101:2082-2087 [Extract] [Full Text] [PDF]  

Correction for Seet et al., Analysis of an orf virus chemokine-binding protein: Shifting ligand specificities among a family of poxvirus viroceptors, PNAS 2003 100:15137-15142 [Extract] [Full Text] [PDF]  

Correction for Wheeler et al., Memory's echo: Vivid remembering reactivates sensory-specific cortex, PNAS 2000 97:11125-11129 [Extract] [Full Text] [PDF]