
Cover image: Crystal structure of a nucleosome-polyamide complex. DNA (gray and brown) is wound twice around the core histone complex (blue, green, orange, and yellow) to form the nucleosome. A polyamide linker (pink polymer) tethers the aligned major groove at two sites 80 bp apart on the DNA. See the article by Edayathamungalam et al. on pages 6864–6869.