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COMMENTARIES

Stanton Q. Smith and Tappey H. Jones

Tracking the cryptic pumiliotoxins
PNAS 2004 101: 7841-7842; published online before print May 17 2004, 10.1073/pnas.0402599101 [Extract] [Full Text] [PDF]  
See companion article on page 8045

PHYSICAL SCIENCES

Applied Physical Sciences

Robert McDermott, SeungKyun Lee, Bennie ten Haken, Andreas H. Trabesinger, Alexander Pines, and John Clarke

Microtesla MRI with a superconducting quantum interference device
PNAS 2004 101: 7857-7861; published online before print May 12 2004, 10.1073/pnas.0402382101 [Abstract] [Full Text] [PDF]  

Chemistry

Janine Mauzeroll and Allen J. Bard

Scanning electrochemical microscopy of menadione-glutathione conjugate export from yeast cells
PNAS 2004 101: 7862-7867; published online before print May 17 2004, 10.1073/pnas.0402556101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Rebecca A. Butcher and Stuart L. Schreiber

Identification of Ald6p as the target of a class of small-molecule suppressors of FK506 and their use in network dissection
PNAS 2004 101: 7868-7873; published online before print May 14 2004, 10.1073/pnas.0402317101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Ralph A. Saporito, H. Martin Garraffo, Maureen A. Donnelly, Adam L. Edwards, John T. Longino, and John W. Daly From the Cover: Formicine ants: An arthropod source for the pumiliotoxin alkaloids of dendrobatid poison frogs PNAS 2004 101: 8045-8050; published online before print May 5 2004, 10.1073/pnas.0402365101 [Abstract] [Full Text] [PDF]   See Commentary on page 7841

Engineering

Z. Suo and W. Hong

Programmable motion and patterning of molecules on solid surfaces
PNAS 2004 101: 7874-7879; published online before print May 11 2004, 10.1073/pnas.0308254101 [Abstract] [Full Text] [PDF]  

Geophysics

G. Verri, R. Barkai, C. Bordeanu, A. Gopher, M. Hass, A. Kaufman, P. Kubik, E. Montanari, M. Paul, A. Ronen, S. Weiner, and E. Boaretto

Flint mining in prehistory recorded by in situ-produced cosmogenic ¹⁰Be
PNAS 2004 101: 7880-7884; published online before print May 17 2004, 10.1073/pnas.0402302101 [Abstract] [Full Text] [PDF]  

Statistics

Jie Peng and D. Siegmund Inaugural Article by a Recently Elected Academy Member: Inaugural Article: Mapping quantitative traits with random and with ascertained sibships PNAS 2004 101: 7845-7850; published online before print April 14 2004, 10.1073/pnas.0401713101 [Abstract] [Full Text] [PDF]

SOCIAL SCIENCES

BIOLOGICAL SCIENCES

Biochemistry

Andrey V. Kajava, Ulrich Baxa, Reed B. Wickner, and Alasdair C. Steven

A model for Ure2p prion filaments and other amyloids: The parallel superpleated -structure
PNAS 2004 101: 7885-7890; published online before print May 13 2004, 10.1073/pnas.0402427101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Yanhong Zhang and Neil Hogg

The mechanism of transmembrane S-nitrosothiol transport
PNAS 2004 101: 7891-7896; published online before print May 17 2004, 10.1073/pnas.0401167101 [Abstract] [Full Text] [PDF]  

Annette Sievers, Malte Beringer, Marina V. Rodnina, and Richard Wolfenden From the Cover: The ribosome as an entropy trap PNAS 2004 101: 7897-7901; published online before print May 12 2004, 10.1073/pnas.0402488101 [Abstract] [Full Text] [PDF]

Iwona Buskiewicz, Elke Deuerling, Shan-Qing Gu, Johannes Jöckel, Marina V. Rodnina, Bernd Bukau, and Wolfgang Wintermeyer

Trigger factor binds to ribosome–signal-recognition particle (SRP) complexes and is excluded by binding of the SRP receptor
PNAS 2004 101: 7902-7906; published online before print May 17 2004, 10.1073/pnas.0402231101 [Abstract] [Full Text] [PDF]  

Malin Allert, Shahir S. Rizk, Loren L. Looger, and Homme W. Hellinga

Computational design of receptors for an organophosphate surrogate of the nerve agent soman
PNAS 2004 101: 7907-7912; published online before print May 17 2004, 10.1073/pnas.0401309101 [Abstract] [Full Text] [PDF]  

Olafur Th. Magnusson, Hirohide Toyama, Megumi Saeki, Ana Rojas, John C. Reed, Robert C. Liddington, Judith P. Klinman, and Robert Schwarzenbacher

Quinone biogenesis: Structure and mechanism of PqqC, the final catalyst in the production of pyrroloquinoline quinone
PNAS 2004 101: 7913-7918; published online before print May 17 2004, 10.1073/pnas.0402640101 [Abstract] [Full Text] [PDF] [Supporting Table]  

Kechao Yang and William W. Metcalf

A new activity for an old enzyme: Escherichia coli bacterial alkaline phosphatase is a phosphite-dependent hydrogenase
PNAS 2004 101: 7919-7924; published online before print May 17 2004, 10.1073/pnas.0400664101 [Abstract] [Full Text] [PDF] [Supporting Tables]  

Ghadiyaram Chakshusmathi, Kajari Mondal, G. Santosh Lakshmi, Guramrit Singh, Ankita Roy, Ravindra Babu Ch., S. Madhusudhanan, and Raghavan Varadarajan

Design of temperature-sensitive mutants solely from amino acid sequence
PNAS 2004 101: 7925-7930; published online before print May 17 2004, 10.1073/pnas.0402222101 [Abstract] [Full Text] [PDF] [Supporting figures]  

Ken Okamoto, Koji Matsumoto, Russ Hille, Bryan T. Eger, Emil F. Pai, and Takeshi Nishino

The crystal structure of xanthine oxidoreductase during catalysis: Implications for reaction mechanism and enzyme inhibition
PNAS 2004 101: 7931-7936; published online before print May 17 2004, 10.1073/pnas.0400973101 [Abstract] [Full Text] [PDF]  

Yakir Moshe, Jérôme Boulaire, Michele Pagano, and Avram Hershko

Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
PNAS 2004 101: 7937-7942; published online before print May 17 2004, 10.1073/pnas.0402442101 [Abstract] [Full Text] [PDF]  

Sanjai Kumar, Bo Zhou, Fubo Liang, Wei-Qing Wang, Zhonghui Huang, and Zhong-Yin Zhang

Activity-based probes for protein tyrosine phosphatases
PNAS 2004 101: 7943-7948; published online before print May 17 2004, 10.1073/pnas.0402323101 [Abstract] [Full Text] [PDF] [Supporting Text]  

Biophysics

Tatsiana Lobovkina, Paul Dommersnes, Jean-Francois Joanny, Patricia Bassereau, Mattias Karlsson, and Owe Orwar

Mechanical tweezer action by self-tightening knots in surfactant nanotubes
PNAS 2004 101: 7949-7953; published online before print May 12 2004, 10.1073/pnas.0401760101 [Abstract] [Full Text] [PDF]  

Ariel A. Di Nardo, Dmitry M. Korzhnev, Peter J. Stogios, Arash Zarrine-Afsar, Lewis E. Kay, and Alan R. Davidson

Dramatic acceleration of protein folding by stabilization of a nonnative backbone conformation
PNAS 2004 101: 7954-7959; published online before print May 17 2004, 10.1073/pnas.0400550101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Trinh Xuan Hoang, Antonio Trovato, Flavio Seno, Jayanth R. Banavar, and Amos Maritan

Geometry and symmetry presculpt the free-energy landscape of proteins
PNAS 2004 101: 7960-7964; published online before print May 17 2004, 10.1073/pnas.0402525101 [Abstract] [Full Text] [PDF]  

Irene A. Chen and Jack W. Szostak

Membrane growth can generate a transmembrane pH gradient in fatty acid vesicles
PNAS 2004 101: 7965-7970; published online before print May 17 2004, 10.1073/pnas.0308045101 [Abstract] [Full Text] [PDF]  

Géza I. Groma, Anne Colonna, Jean-Christophe Lambry, Jacob W. Petrich, György Váró, Manuel Joffre, Marten H. Vos, and Jean-Louis Martin

Resonant optical rectification in bacteriorhodopsin
PNAS 2004 101: 7971-7975; published online before print May 17 2004, 10.1073/pnas.0306789101 [Abstract] [Full Text] [PDF]  

Alan R. Fersht and Satoshi Sato

-Value analysis and the nature of protein-folding transition states
PNAS 2004 101: 7976-7981; published online before print May 18 2004, 10.1073/pnas.0402684101 [Abstract] [Full Text] [PDF]  

Cell Biology

C. Allison Gray, David L. Adelson, Fuller W. Bazer, Robert C. Burghardt, Els N. T. Meeusen, and Thomas E. Spencer

Discovery and characterization of an epithelial-specific galectin in the endometrium that forms crystals in the trophectoderm
PNAS 2004 101: 7982-7987; published online before print May 17 2004, 10.1073/pnas.0402669101 [Abstract] [Full Text] [PDF]  

Damien Arnoult, Laura M. Bartle, Anna Skaletskaya, Delphine Poncet, Naoufal Zamzami, Peter U. Park, Juanita Sharpe, Richard J. Youle, and Victor S. Goldmacher

Cytomegalovirus cell death suppressor vMIA blocks Bax- but not Bak-mediated apoptosis by binding and sequestering Bax at mitochondria
PNAS 2004 101: 7988-7993; published online before print May 17 2004, 10.1073/pnas.0401897101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Nywana Sizemore, Anju Agarwal, Kingshuk Das, Natalia Lerner, Michael Sulak, Sandhya Rani, Richard Ransohoff, David Shultz, and George R. Stark

Inhibitor of B kinase is required to activate a subset of interferon -stimulated genes
PNAS 2004 101: 7994-7998; published online before print May 17 2004, 10.1073/pnas.0401593101 [Abstract] [Full Text] [PDF]  

Ahmet Koc, Audrey P. Gasch, Julian C. Rutherford, Hwa-Young Kim, and Vadim N. Gladyshev

Methionine sulfoxide reductase regulation of yeast lifespan reveals reactive oxygen species-dependent and -independent components of aging
PNAS 2004 101: 7999-8004; published online before print May 12 2004, 10.1073/pnas.0307929101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Ying Yu, Karen S. Moulton, Mohamed K. Khan, Sabrina Vineberg, Eileen Boye, Vannessa M. Davis, Peter E. O'Donnell, Joyce Bischoff, and David S. Milstone

E-selectin is required for the antiangiogenic activity of endostatin
PNAS 2004 101: 8005-8010; published online before print May 17 2004, 10.1073/pnas.0402551101 [Abstract] [Full Text] [PDF]  

Developmental Biology

Yunhan Hong, Tongming Liu, Haobin Zhao, Hongyan Xu, Weijia Wang, Rong Liu, Tiansheng Chen, Jiaorong Deng, and Jianfang Gui

Establishment of a normal medakafish spermatogonial cell line capable of sperm production in vitro
PNAS 2004 101: 8011-8016; published online before print May 12 2004, 10.1073/pnas.0308668101 [Abstract] [Full Text] [PDF] [Supporting Text]  

Kiyotoshi Satoh, Mana Kasai, Takefumi Ishidao, Kenichi Tago, Susumu Ohwada, Yoshimi Hasegawa, Takao Senda, Shinji Takada, Shigeyuki Nada, Tsutomu Nakamura, and Tetsu Akiyama

Anteriorization of neural fate by inhibitor of -catenin and T cell factor (ICAT), a negative regulator of Wnt signaling
PNAS 2004 101: 8017-8021; published online before print May 17 2004, 10.1073/pnas.0401733101 [Abstract] [Full Text] [PDF]  

Viravuth P. Yin and Carl S. Thummel

A balance between the diap1 death inhibitor and reaper and hid death inducers controls steroid-triggered cell death in Drosophila
PNAS 2004 101: 8022-8027; published online before print May 18 2004, 10.1073/pnas.0402647101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Kien C. Luu, Gui Ying Nie, and Lois A. Salamonsen

Endometrial calbindins are critical for embryo implantation: Evidence from in vivo use of morpholino antisense oligonucleotides
PNAS 2004 101: 8028-8033; published online before print May 11 2004, 10.1073/pnas.0401069101 [Abstract] [Full Text] [PDF]  

Sonja Schaetzlein, Andrea Lucas-Hahn, Erika Lemme, Wilfried A. Kues, Martina Dorsch, Michael P. Manns, Heiner Niemann, and K. Lenhard Rudolph

Telomere length is reset during early mammalian embryogenesis
PNAS 2004 101: 8034-8038; published online before print May 17 2004, 10.1073/pnas.0402400101 [Abstract] [Full Text] [PDF]  

Anders Nordström, Petr Tarkowski, Danuse Tarkowska, Rikke Norbaek, Crister Åstot, Karel Dolezal, and Göran Sandberg

Auxin regulation of cytokinin biosynthesis in Arabidopsis thaliana: A factor of potential importance for auxin–cytokinin-regulated development
PNAS 2004 101: 8039-8044; published online before print May 14 2004, 10.1073/pnas.0402504101 [Abstract] [Full Text] [PDF]  

Ecology

Nathaniel T. Wheelwright and Barry A. Logan

Previous-year reproduction reduces photosynthetic capacity and slows lifetime growth in females of a neotropical tree
PNAS 2004 101: 8051-8055; published online before print May 17 2004, 10.1073/pnas.0402735101 [Abstract] [Full Text] [PDF]  

Evolution

M. A. Gandolfo, K. C. Nixon, and W. L. Crepet

Cretaceous flowers of Nymphaeaceae and implications for complex insect entrapment pollination mechanisms in early Angiosperms
PNAS 2004 101: 8056-8060; published online before print May 17 2004, 10.1073/pnas.0402473101 [Abstract] [Full Text] [PDF]  

Steven A. Frank

Genetic variation in cancer predisposition: Mutational decay of a robust genetic control network
PNAS 2004 101: 8061-8065; published online before print May 12 2004, 10.1073/pnas.0400561101 [Abstract] [Full Text] [PDF]  

Sergey I. Nikolaev, Cédric Berney, José F. Fahrni, Ignacio Bolivar, Stephane Polet, Alexander P. Mylnikov, Vladimir V. Aleshin, Nikolai B. Petrov, and Jan Pawlowski From the Cover: The twilight of Heliozoa and rise of Rhizaria, an emerging supergroup of amoeboid eukaryotes PNAS 2004 101: 8066-8071; published online before print May 17 2004, 10.1073/pnas.0308602101 [Abstract] [Full Text] [PDF] [Supporting Information]

R. Craig MacLean, Graham Bell, and Paul B. Rainey

The evolution of a pleiotropic fitness tradeoff in Pseudomonas fluorescens
PNAS 2004 101: 8072-8077; published online before print May 18 2004, 10.1073/pnas.0307195101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Genetics

Rebecca A. Butcher and Stuart L. Schreiber

Identification of Ald6p as the target of a class of small-molecule suppressors of FK506 and their use in network dissection
PNAS 2004 101: 7868-7873; published online before print May 14 2004, 10.1073/pnas.0402317101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Ee Sin Chen, Takashi Sutani, and Mitsuhiro Yanagida

Cti1/C1D interacts with condensin SMC hinge and supports the DNA repair function of condensin
PNAS 2004 101: 8078-8083; published online before print May 17 2004, 10.1073/pnas.0307976101 [Abstract] [Full Text] [PDF]  

Cheng Huang, Chengjie Xiong, and Kerry Kornfeld

Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans
PNAS 2004 101: 8084-8089; published online before print May 12 2004, 10.1073/pnas.0400848101 [Abstract] [Full Text] [PDF]  

Rainer G. Ruf, Pin-Xian Xu, Derek Silvius, Edgar A. Otto, Frank Beekmann, Ulla T. Muerb, Shrawan Kumar, Thomas J. Neuhaus, Markus J. Kemper, Richard M. Raymond, Jr., Patrick D. Brophy, Jennifer Berkman, Michael Gattas, Valentine Hyland, Eva-Maria Ruf, Charles Schwartz, Eugene H. Chang, Richard J. H. Smith, Constantine A. Stratakis, Dominique Weil, Christine Petit, and Friedhelm Hildebrandt

SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1–SIX1–DNA complexes
PNAS 2004 101: 8090-8095; published online before print May 12 2004, 10.1073/pnas.0308475101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Qiliang Li, Xiangdong Fang, Hemei Han, and George Stamatoyannopoulos

The minimal promoter plays a major role in silencing of the galago -globin gene in adult erythropoiesis
PNAS 2004 101: 8096-8101; published online before print May 17 2004, 10.1073/pnas.0402594101 [Abstract] [Full Text] [PDF]  

Immunology

Laurent Poirot, Christophe Benoist, and Diane Mathis

Natural killer cells distinguish innocuous and destructive forms of pancreatic islet autoimmunity
PNAS 2004 101: 8102-8107; published online before print May 12 2004, 10.1073/pnas.0402065101 [Abstract] [Full Text] [PDF] [Supporting Table]  

Brian Zarnegar, Jeannie Q. He, Gagik Oganesyan, Alexander Hoffmann, David Baltimore, and Genhong Cheng

Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-B activation pathways
PNAS 2004 101: 8108-8113; published online before print May 17 2004, 10.1073/pnas.0402629101 [Abstract] [Full Text] [PDF]  

Kefang Xie, Mark P. Sowden, Geoffrey S. C. Dance, Andrew T. Torelli, Harold C. Smith, and Joseph E. Wedekind

The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1
PNAS 2004 101: 8114-8119; published online before print May 17 2004, 10.1073/pnas.0400493101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Kai Sun, Lisbeth A. Welniak, Angela Panoskaltsis-Mortari, Matthew J. O'Shaughnessy, Haiyan Liu, Isabel Barao, William Riordan, Raquel Sitcheran, Christian Wysocki, Jonathan S. Serody, Bruce R. Blazar, Thomas J. Sayers, and William J. Murphy

Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib
PNAS 2004 101: 8120-8125; published online before print May 17 2004, 10.1073/pnas.0401563101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Makoto Ohtsuka, Hisashi Arase, Arata Takeuchi, Sho Yamasaki, Ritsuko Shiina, Tadahiro Suenaga, Daiju Sakurai, Tadashi Yokosuka, Noriko Arase, Makio Iwashima, Toshio Kitamura, Hideshige Moriya, and Takashi Saito

NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling
PNAS 2004 101: 8126-8131; published online before print May 13 2004, 10.1073/pnas.0401119101 [Abstract] [Full Text] [PDF]  

Medical Sciences

Tetsufumi Koike, Naoko Kimura, Keiko Miyazaki, Tomonori Yabuta, Kensuke Kumamoto, Seiichi Takenoshita, Jian Chen, Masanobu Kobayashi, Masuo Hosokawa, Akiyoshi Taniguchi, Tetsuhito Kojima, Nobuhiro Ishida, Masao Kawakita, Harumi Yamamoto, Hiromu Takematsu, Akemi Suzuki, Yasunori Kozutsumi, and Reiji Kannagi

Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates
PNAS 2004 101: 8132-8137; published online before print May 12 2004, 10.1073/pnas.0402088101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Kathrin Maedler, Pavel Sergeev, Jan A. Ehses, Zoltan Mathe, Domenico Bosco, Thierry Berney, Jean-Michel Dayer, Manfred Reinecke, Philippe A. Halban, and Marc Y. Donath

Leptin modulates cell expression of IL-1 receptor antagonist and release of IL-1 in human islets
PNAS 2004 101: 8138-8143; published online before print May 12 2004, 10.1073/pnas.0305683101 [Abstract] [Full Text] [PDF]  

Hiroyuki Yoshida, Wenjun Cheng, Jamie Hung, Denise Montell, Erika Geisbrecht, Daniel Rosen, Jinsong Liu, and Honami Naora

Lessons from border cell migration in the Drosophila ovary: A role for myosin VI in dissemination of human ovarian cancer
PNAS 2004 101: 8144-8149; published online before print May 14 2004, 10.1073/pnas.0400400101 [Abstract] [Full Text] [PDF]  

Paul C. Zamecnik, Malay K. Raychowdhury, David R. Tabatadze, and Horacio F. Cantiello

Reversal of cystic fibrosis phenotype in a cultured 508 cystic fibrosis transmembrane conductance regulator cell line by oligonucleotide insertion
PNAS 2004 101: 8150-8155; published online before print May 17 2004, 10.1073/pnas.0401933101 [Abstract] [Full Text] [PDF]  

Microbiology

Y. Guan, L. L. M. Poon, C. Y. Cheung, T. M. Ellis, W. Lim, A. S. Lipatov, K. H. Chan, K. M. Sturm-Ramirez, C. L. Cheung, Y. H. C. Leung, K. Y. Yuen, R. G. Webster, and J. S. M. Peiris

H5N1 influenza: A protean pandemic threat
PNAS 2004 101: 8156-8161; published online before print May 17 2004, 10.1073/pnas.0402443101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Neuroscience

Ruiben Feng, Huimin Wang, Jianlin Wang, David Shrom, Xuemei Zeng, and Joe Z. Tsien

Forebrain degeneration and ventricle enlargement caused by double knockout of Alzheimer's presenilin-1 and presenilin-2
PNAS 2004 101: 8162-8167; published online before print May 17 2004, 10.1073/pnas.0402733101 [Abstract] [Full Text] [PDF] [Supporting Text]  

Matthew J. Craner, Jia Newcombe, Joel A. Black, Caroline Hartle, M. Louise Cuzner, and Stephen G. Waxman

Molecular changes in neurons in multiple sclerosis: Altered axonal expression of Na_v1.2 and Na_v1.6 sodium channels and Na⁺/Ca²+ exchanger
PNAS 2004 101: 8168-8173; published online before print May 17 2004, 10.1073/pnas.0402765101 [Abstract] [Full Text] [PDF]  

Nitin Gogtay, Jay N. Giedd, Leslie Lusk, Kiralee M. Hayashi, Deanna Greenstein, A. Catherine Vaituzis, Tom F. Nugent, III, David H. Herman, Liv S. Clasen, Arthur W. Toga, Judith L. Rapoport, and Paul M. Thompson From the Cover: Dynamic mapping of human cortical development during childhood through early adulthood PNAS 2004 101: 8174-8179; published online before print May 17 2004, 10.1073/pnas.0402680101 [Abstract] [Full Text] [PDF] [Supporting Movies]

Jonathan Kipnis, Hagit Cohen, Michal Cardon, Yaniv Ziv, and Michal Schwartz

T cell deficiency leads to cognitive dysfunction: Implications for therapeutic vaccination for schizophrenia and other psychiatric conditions
PNAS 2004 101: 8180-8185; published online before print May 12 2004, 10.1073/pnas.0402268101 [Abstract] [Full Text] [PDF] [Supporting Text]  

John F. Cryan, Olivia F. O'Leary, Sung-Ha Jin, Julie C. Friedland, Ming Ouyang, Bradford R. Hirsch, Michelle E. Page, Ashutosh Dalvi, Steven A. Thomas, and Irwin Lucki

Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors
PNAS 2004 101: 8186-8191; published online before print May 17 2004, 10.1073/pnas.0401080101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Anne Kemp and Denise Manahan-Vaughan

Hippocampal long-term depression and long-term potentiation encode different aspects of novelty acquisition
PNAS 2004 101: 8192-8197; published online before print May 18 2004, 10.1073/pnas.0402650101 [Abstract] [Full Text] [PDF]  

Pharmacology

Ming-Kuei Jang, Dale F. Mierke, Shelley J. Russek, and David H. Farb

A steroid modulatory domain on NR2B controls N-methyl-D-aspartate receptor proton sensitivity
PNAS 2004 101: 8198-8203; published online before print May 18 2004, 10.1073/pnas.0401838101 [Abstract] [Full Text] [PDF]  

Physiology

C. P. Sibley, P. M. Coan, A. C. Ferguson-Smith, W. Dean, J. Hughes, P. Smith, W. Reik, G. J. Burton, A. L. Fowden, and M. Constância

Placental-specific insulin-like growth factor 2 (Igf2) regulates the diffusional exchange characteristics of the mouse placenta
PNAS 2004 101: 8204-8208; published online before print May 18 2004, 10.1073/pnas.0402508101 [Abstract] [Full Text] [PDF]  

Ioannis Charalampopoulos, Christos Tsatsanis, Erene Dermitzaki, Vasilia-Ismini Alexaki, Elias Castanas, Andrew N. Margioris, and Achille Gravanis

Dehydroepiandrosterone and allopregnanolone protect sympathoadrenal medulla cells against apoptosis via antiapoptotic Bcl-2 proteins
PNAS 2004 101: 8209-8214; published online before print May 17 2004, 10.1073/pnas.0306631101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Richard Warth, Hervé Barrière, Pierre Meneton, May Bloch, Jörg Thomas, Michel Tauc, Dirk Heitzmann, Elisa Romeo, François Verrey, Raymond Mengual, Nicolas Guy, Saïd Bendahhou, Florian Lesage, Philippe Poujeol, and Jacques Barhanin

Proximal renal tubular acidosis in TASK2 K⁺ channel-deficient mice reveals a mechanism for stabilizing bicarbonate transport
PNAS 2004 101: 8215-8220; published online before print May 12 2004, 10.1073/pnas.0400081101 [Abstract] [Full Text] [PDF]  

Estelle Cormet-Boyaka, Michael Jablonsky, Anjaparavanda P. Naren, Patricia L. Jackson, Donald D. Muccio, and Kevin L. Kirk

Rescuing cystic fibrosis transmembrane conductance regulator (CFTR)-processing mutants by transcomplementation
PNAS 2004 101: 8221-8226; published online before print May 12 2004, 10.1073/pnas.0400459101 [Abstract] [Full Text] [PDF]  

Katherine E. Wortley, Keith D. Anderson, Karen Garcia, Jane D. Murray, Lubomira Malinova, Rong Liu, Marshena Moncrieffe, Karen Thabet, Hilary J. Cox, George D. Yancopoulos, Stanley J. Wiegand, and Mark W. Sleeman

Genetic deletion of ghrelin does not decrease food intake but influences metabolic fuel preference
PNAS 2004 101: 8227-8232; published online before print May 17 2004, 10.1073/pnas.0402763101 [Abstract] [Full Text] [PDF]  

Plant Biology

X. Qi, S. Bakht, M. Leggett, C. Maxwell, R. Melton, and A. Osbourn

A gene cluster for secondary metabolism in oat: Implications for the evolution of metabolic diversity in plants
PNAS 2004 101: 8233-8238; published online before print May 17 2004, 10.1073/pnas.0401301101 [Abstract] [Full Text] [PDF] [Supporting Table]  

Meena R. Chandok, Sophia K. Ekengren, Gregory B. Martin, and Daniel F. Klessig

Suppression of pathogen-inducible NO synthase (iNOS) activity in tomato increases susceptibility to Pseudomonas syringae
PNAS 2004 101: 8239-8244; published online before print May 14 2004, 10.1073/pnas.0402344101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Erich Glawischnig, Bjarne Gram Hansen, Carl Erik Olsen, and Barbara Ann Halkier

Camalexin is synthesized from indole-3-acetaldoxime, a key branching point between primary and secondary metabolism in Arabidopsis
PNAS 2004 101: 8245-8250; published online before print May 17 2004, 10.1073/pnas.0305876101 [Abstract] [Full Text] [PDF]  

Population Biology

Geoffrey P. Jones, Mark I. McCormick, Maya Srinivasan, and Janelle V. Eagle

Coral decline threatens fish biodiversity in marine reserves
PNAS 2004 101: 8251-8253; published online before print May 18 2004, 10.1073/pnas.0401277101 [Abstract] [Full Text] [PDF]  

CORRECTIONS

Correction for Carroll et al., Mechanisms for activating Cu- and Zn-containing superoxide dismutase in the absence of the CCS Cu chaperone, PNAS 2004 101:5964-5969 [Extract] [Full Text] [PDF]