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COMMENTARIES

Mark D. Wewers

IL-1: An endosomal exit
PNAS 2004 101: 10241-10242; published online before print July 6 2004, 10.1073/pnas.0403971101 [Extract] [Full Text] [PDF]  

PHYSICAL SCIENCES

Applied Physical Sciences

M. Léonetti, E. Dubois-Violette, and F. Homblé

Pattern formation of stationary transcellular ionic currents in Fucus
PNAS 2004 101: 10243-10248; published online before print July 1 2004, 10.1073/pnas.0402335101 [Abstract] [Full Text] [PDF]  

Chemistry

Marcel Ovidiu Vlad, L. Luca Cavalli-Sforza, and John Ross

Enhanced (hydrodynamic) transport induced by population growth in reaction–diffusion systems with application to population genetics
PNAS 2004 101: 10249-10253; published online before print July 1 2004, 10.1073/pnas.0403419101 [Abstract] [Full Text] [PDF]  

SOCIAL SCIENCES

BIOLOGICAL SCIENCES

Biochemistry

Frédéric Eghiaian, Jeanne Grosclaude, Stéphanie Lesceu, Pascale Debey, Bénédicte Doublet, Eric Tréguer, Human Rezaei, and Marcel Knossow

Insight into the PrP^C PrP^Sc conversion from the structures of antibody-bound ovine prion scrapie-susceptibility variants
PNAS 2004 101: 10254-10259; published online before print July 6 2004, 10.1073/pnas.0400014101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Dragana Korencic, Ivan Ahel, James Schelert, Meik Sacher, Benfang Ruan, Constantinos Stathopoulos, Paul Blum, Michael Ibba, and Dieter Söll

A freestanding proofreading domain is required for protein synthesis quality control in Archaea
PNAS 2004 101: 10260-10265; published online before print July 6 2004, 10.1073/pnas.0403926101 [Abstract] [Full Text] [PDF]  

Ingo Heilmann, Mark S. Pidkowich, Thomas Girke, and John Shanklin From the Cover: Switching desaturase enzyme specificity by alternate subcellular targeting PNAS 2004 101: 10266-10271; published online before print July 6 2004, 10.1073/pnas.0402200101 [Abstract] [Full Text] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Biophysics

Yongbo Zhang and Erik R. P. Zuiderweg

The 70-kDa heat shock protein chaperone nucleotide-binding domain in solution unveiled as a molecular machine that can reorient its functional subdomains
PNAS 2004 101: 10272-10277; published online before print July 1 2004, 10.1073/pnas.0401313101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Martin Margittai and Ralf Langen

Template-assisted filament growth by parallel stacking of tau
PNAS 2004 101: 10278-10283; published online before print July 6 2004, 10.1073/pnas.0401911101 [Abstract] [Full Text] [PDF]  

Sylvie Doublié, Viswanath Bandaru, Jeffrey P. Bond, and Susan S. Wallace

The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity
PNAS 2004 101: 10284-10289; published online before print July 1 2004, 10.1073/pnas.0402051101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Cell Biology

Lei Zhang, Ole Gjoerup, and Thomas M. Roberts

The serine/threonine kinase cyclin G-associated kinase regulates epidermal growth factor receptor signaling
PNAS 2004 101: 10296-10301; published online before print July 6 2004, 10.1073/pnas.0403175101 [Abstract] [Full Text] [PDF]  

Guang W. Wong, Jin Wang, Christopher Hug, Tsu-Shuen Tsao, and Harvey F. Lodish

A family of Acrp30/adiponectin structural and functional paralogs
PNAS 2004 101: 10302-10307; published online before print July 1 2004, 10.1073/pnas.0403760101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Christopher Hug, Jin Wang, Naina Shehzeen Ahmad, Jonathan S. Bogan, Tsu-Shuen Tsao, and Harvey F. Lodish

T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin
PNAS 2004 101: 10308-10313; published online before print June 21 2004, 10.1073/pnas.0403382101 [Abstract] [Full Text] [PDF]  

Beate F. Krakstad, Vandana V. Ardawatia, and Anna M. Aragay

A role for G₁₂/G₁₃ in p120^ctn regulation
PNAS 2004 101: 10314-10319; published online before print July 6 2004, 10.1073/pnas.0401366101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Developmental Biology

Michael Schubert, Nicholas D. Holland, Hector Escriva, Linda Z. Holland, and Vincent Laudet

Retinoic acid influences anteroposterior positioning of epidermal sensory neurons and their gene expression in a developing chordate (amphioxus)
PNAS 2004 101: 10320-10325; published online before print June 29 2004, 10.1073/pnas.0403216101 [Abstract] [Full Text] [PDF]  

Toshio Hamatani, Takiko Daikoku, Haibin Wang, Hiromichi Matsumoto, Mark G. Carter, Minoru S. H. Ko, and Sudhansu K. Dey

Global gene expression analysis identifies molecular pathways distinguishing blastocyst dormancy and activation
PNAS 2004 101: 10326-10331; published online before print July 1 2004, 10.1073/pnas.0402597101 [Abstract] [Full Text] [PDF] [Supporting Tables]  

Wilfried Mai, Marc F. Janier, Nathalie Allioli, Laure Quignodon, Thomas Chuzel, Frédéric Flamant, and Jacques Samarut

Thyroid hormone receptor is a molecular switch of cardiac function between fetal and postnatal life
PNAS 2004 101: 10332-10337; published online before print July 6 2004, 10.1073/pnas.0401843101 [Abstract] [Full Text] [PDF]  

Yoshiki Hayashi, Makoto Hayashi, and Satoru Kobayashi

Nanos suppresses somatic cell fate in Drosophila germ line
PNAS 2004 101: 10338-10342; published online before print July 6 2004, 10.1073/pnas.0401647101 [Abstract] [Full Text] [PDF]  

Francesca M. Theriault, Priscillia Roy, and Stefano Stifani

AML1/Runx1 is important for the development of hindbrain cholinergic branchiovisceral motor neurons and selected cranial sensory neurons
PNAS 2004 101: 10343-10348; published online before print July 6 2004, 10.1073/pnas.0400768101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Evolution

Kevin C. Rowe, Edward J. Heske, Patrick W. Brown, and Ken N. Paige

Surviving the ice: Northern refugia and postglacial colonization
PNAS 2004 101: 10355-10359; published online before print July 12 2004, 10.1073/pnas.0401338101 [Abstract] [Full Text] [PDF] [Supporting Information]  

C. P. Osborne, D. J. Beerling, B. H. Lomax, and W. G. Chaloner From the Cover: Biophysical constraints on the origin of leaves inferred from the fossil record PNAS 2004 101: 10360-10362; published online before print July 6 2004, 10.1073/pnas.0402787101 [Abstract] [Full Text] [PDF] [Supporting Table]

David M. Shuker and Stuart A. West

Information constraints and the precision of adaptation: Sex ratio manipulation in wasps
PNAS 2004 101: 10363-10367; published online before print July 6 2004, 10.1073/pnas.0308034101 [Abstract] [Full Text] [PDF]  

Robert Sutak, Pavel Dolezal, Heather L. Fiumera, Ivan Hrdy, Andrew Dancis, Maria Delgadillo-Correa, Patricia J. Johnson, Miklós Müller, and Jan Tachezy From the Cover: Mitochondrial-type assembly of FeS centers in the hydrogenosomes of the amitochondriate eukaryote Trichomonas vaginalis PNAS 2004 101: 10368-10373; published online before print June 29 2004, 10.1073/pnas.0401319101 [Abstract] [Full Text] [PDF] [Supporting Text]

David P. Cowan and Julie K. Stahlhut

Functionally reproductive diploid and haploid males in an inbreeding hymenopteran with complementary sex determination
PNAS 2004 101: 10374-10379; published online before print July 1 2004, 10.1073/pnas.0402481101 [Abstract] [Full Text] [PDF]  

Genetics

Marcel Ovidiu Vlad, L. Luca Cavalli-Sforza, and John Ross

Enhanced (hydrodynamic) transport induced by population growth in reaction–diffusion systems with application to population genetics
PNAS 2004 101: 10249-10253; published online before print July 1 2004, 10.1073/pnas.0403419101 [Abstract] [Full Text] [PDF]  

Andrea Ventura, Alexander Meissner, Christopher P. Dillon, Michael McManus, Phillip A. Sharp, Luk Van Parijs, Rudolf Jaenisch, and Tyler Jacks

Cre-lox-regulated conditional RNA interference from transgenes
PNAS 2004 101: 10380-10385; published online before print July 6 2004, 10.1073/pnas.0403954101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Shaw-Hwa Lo and Tian Zheng

A demonstration and findings of a statistical approach through reanalysis of inflammatory bowel disease data
PNAS 2004 101: 10386-10391; published online before print July 1 2004, 10.1073/pnas.0403662101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Immunology

Jeffrey M. Beekman, Jantine E. Bakema, Jan G. J. van de Winkel, and Jeanette H. W. Leusen

Direct interaction between FcRI (CD64) and periplakin controls receptor endocytosis and ligand binding capacity
PNAS 2004 101: 10392-10397; published online before print June 30 2004, 10.1073/pnas.0401217101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Silke Paust, Linrong Lu, Nami McCarty, and Harvey Cantor

Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease
PNAS 2004 101: 10398-10403; published online before print July 2 2004, 10.1073/pnas.0403342101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Gianluca Moroncini, Nnennaya Kanu, Laura Solforosi, Gil Abalos, Glenn C. Telling, Mark Head, James Ironside, Jeremy P. Brockes, Dennis R. Burton, and R. Anthony Williamson

Motif-grafted antibodies containing the replicative interface of cellular PrP are specific for PrP^Sc
PNAS 2004 101: 10404-10409; published online before print July 6 2004, 10.1073/pnas.0403522101 [Abstract] [Full Text] [PDF]  

Kristie M. Grebe, Raedun L. Clarke, and Terry A. Potter

Ligation of CD8 leads to apoptosis of thymocytes that have not undergone positive selection
PNAS 2004 101: 10410-10415; published online before print July 1 2004, 10.1073/pnas.0402079101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Medical Sciences

Kohjiro Ueki, Tatsuya Kondo, Yu-Hua Tseng, and C. Ronald Kahn

Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse
PNAS 2004 101: 10422-10427; published online before print July 6 2004, 10.1073/pnas.0402511101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Laurent Vergnes, Miklós Péterfy, Martin O. Bergo, Stephen G. Young, and Karen Reue

Lamin B1 is required for mouse development and nuclear integrity
PNAS 2004 101: 10428-10433; published online before print July 1 2004, 10.1073/pnas.0401424101 [Abstract] [Full Text] [PDF]  

Bulent O. Yildiz, Marc A. Suchard, Ma-Li Wong, Samuel M. McCann, and Julio Licinio Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity PNAS 2004 101: 10434-10439; published online before print July 1 2004, 10.1073/pnas.0403465101 [Abstract] [Full Text] [PDF] OPEN ACCESS ARTICLE

Tianqing Kong, Holger K. Eltzschig, Jorn Karhausen, Sean P. Colgan, and C. Simon Shelley

Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of ₂ integrin gene expression
PNAS 2004 101: 10440-10445; published online before print July 2 2004, 10.1073/pnas.0401339101 [Abstract] [Full Text] [PDF]  

Xiangqun Gao and Paul Talalay

Induction of phase 2 genes by sulforaphane protects retinal pigment epithelial cells against photooxidative damage
PNAS 2004 101: 10446-10451; published online before print June 30 2004, 10.1073/pnas.0403886101 [Abstract] [Full Text] [PDF]  

Microbiology

Neuroscience

Alexander W. Bruce, Ian J. Donaldson, Ian C. Wood, Sally A. Yerbury, Michael I. Sadowski, Michael Chapman, Berthold Göttgens, and Noel J. Buckley

Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes
PNAS 2004 101: 10458-10463; published online before print July 6 2004, 10.1073/pnas.0401827101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Nadia De Mota, Annabelle Reaux-Le Goazigo, Said El Messari, Nicolas Chartrel, Darren Roesch, Cynthia Dujardin, Claude Kordon, Hubert Vaudry, Françoise Moos, and Catherine Llorens-Cortes

Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release
PNAS 2004 101: 10464-10469; published online before print July 1 2004, 10.1073/pnas.0403518101 [Abstract] [Full Text] [PDF]  

Tamas Bartfai, Xiaoying Lu, Hedieh Badie-Mahdavi, Alasdair M. Barr, Andrey Mazarati, Xiao-Ying Hua, Tony Yaksh, Gebhard Haberhauer, Susana Conde Ceide, Laurent Trembleau, Laszlo Somogyi, Lenz Kröck, and Julius Rebek, Jr.

Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests
PNAS 2004 101: 10470-10475; published online before print July 6 2004, 10.1073/pnas.0403802101 [Abstract] [Full Text] [PDF]  

Kevin C. Daly, Thomas A. Christensen, Hong Lei, Brian H. Smith, and John G. Hildebrand

Learning modulates the ensemble representations for odors in primary olfactory networks
PNAS 2004 101: 10476-10481; published online before print July 1 2004, 10.1073/pnas.0401902101 [Abstract] [Full Text] [PDF] [Supporting Text]  

Physiology

Daniel Fuster, Orson W. Moe, and Donald W. Hilgemann

Lipid- and mechanosensitivities of sodium/hydrogen exchangers analyzed by electrical methods
PNAS 2004 101: 10482-10487; published online before print July 6 2004, 10.1073/pnas.0403930101 [Abstract] [Full Text] [PDF]  

Plant Biology

M. Léonetti, E. Dubois-Violette, and F. Homblé

Pattern formation of stationary transcellular ionic currents in Fucus
PNAS 2004 101: 10243-10248; published online before print July 1 2004, 10.1073/pnas.0402335101 [Abstract] [Full Text] [PDF]  

Carola Holweg and Peter Nick

Arabidopsis myosin XI mutant is defective in organelle movement and polar auxin transport
PNAS 2004 101: 10488-10493; published online before print July 6 2004, 10.1073/pnas.0403155101 [Abstract] [Full Text] [PDF]  

CORRECTIONS

Correction for Koike et al., Hypoxia induces adhesion molecules on cancer cells: A missing link between Warburg effect and induction of selectin-ligand carbohydrates, PNAS 2004 101:8132-8137 [Extract] [Full Text] [PDF]  

Correction for Bachoo et al., Molecular diversity of astrocytes with implications for neurological disorders, PNAS 2004 101:8384-8389 [Extract] [Full Text] [PDF]