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EDITORIAL

Nicholas R. Cozzarelli

Responsible authorship of papers in PNAS
PNAS 2004 101: 10495; published online before print July 12 2004, 10.1073/pnas.0404563101 [Extract] [Full Text] [PDF]  

COMMENTARIES

Kyeongeun Lee and Vineet N. KewalRamani From the Cover: In defense of the cell: TRIM5 interception of mammalian retroviruses PNAS 2004 101: 10496-10497; published online before print July 13 2004, 10.1073/pnas.0404066101 [Extract] [Full Text] [PDF]   See companion article on page 10774 See companion article on page 10780 See companion article on page 10786

PHYSICAL SCIENCES

Applied Physical Sciences

Robert T. Krivacic, Andras Ladanyi, Douglas N. Curry, H. B. Hsieh, Peter Kuhn, Danielle E. Bergsrud, Jane F. Kepros, Todd Barbera, Michael Y. Ho, Lan Bo Chen, Richard A. Lerner, and Richard H. Bruce

A rare-cell detector for cancer
PNAS 2004 101: 10501-10504; published online before print July 12 2004, 10.1073/pnas.0404036101 [Abstract] [Full Text] [PDF]  

Chemistry

Allen R. Buskirk, Yi-Ching Ong, Zev J. Gartner, and David R. Liu

Directed evolution of ligand dependence: Small-molecule-activated protein splicing
PNAS 2004 101: 10505-10510; published online before print July 9 2004, 10.1073/pnas.0402762101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Sarah Delaney, Jae Yoo, Eric D. A. Stemp, and Jacqueline K. Barton

Charge equilibration between two distinct sites in double helical DNA
PNAS 2004 101: 10511-10516; published online before print July 9 2004, 10.1073/pnas.0403791101 [Abstract] [Full Text] [PDF]  

Heather A. Fogarty, Roman Imhof, and Josef Michl From the Cover: Magnetic circular dichroism of peralkylated tetrasilane conformers PNAS 2004 101: 10517-10522; published online before print July 12 2004, 10.1073/pnas.0403209101 [Abstract] [Full Text] [PDF]

Computer Sciences

Eric P. Xing and Richard M. Karp

MotifPrototyper: A Bayesian profile model for motif families
PNAS 2004 101: 10523-10528; published online before print July 13 2004, 10.1073/pnas.0403564101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Statistics

Jing Huang, Alfred Lin, Balasubramanian Narasimhan, Thomas Quertermous, C. Agnes Hsiung, Low-Tone Ho, John S. Grove, Michael Olivier, Koustubh Ranade, Neil J. Risch, and Richard A. Olshen

Tree-structured supervised learning and the genetics of hypertension
PNAS 2004 101: 10529-10534; published online before print July 12 2004, 10.1073/pnas.0403794101 [Abstract] [Full Text] [PDF] [Supporting Text]  

SOCIAL SCIENCES

BIOLOGICAL SCIENCES

Agricultural Sciences

Vinod Kumar, Douglas J. Mills, James D. Anderson, and Autar K. Mattoo

An alternative agriculture system is defined by a distinct expression profile of select gene transcripts and proteins
PNAS 2004 101: 10535-10540; published online before print July 12 2004, 10.1073/pnas.0403496101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Anthropology

Adrienne Zihlman, Debra Bolter, and Christophe Boesch

Wild chimpanzee dentition and its implications for assessing life history in immature hominin fossils
PNAS 2004 101: 10541-10543; published online before print July 8 2004, 10.1073/pnas.0402635101 [Abstract] [Full Text] [PDF]  

Biochemistry

Allen R. Buskirk, Yi-Ching Ong, Zev J. Gartner, and David R. Liu

Directed evolution of ligand dependence: Small-molecule-activated protein splicing
PNAS 2004 101: 10505-10510; published online before print July 9 2004, 10.1073/pnas.0402762101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Sarah Delaney, Jae Yoo, Eric D. A. Stemp, and Jacqueline K. Barton

Charge equilibration between two distinct sites in double helical DNA
PNAS 2004 101: 10511-10516; published online before print July 9 2004, 10.1073/pnas.0403791101 [Abstract] [Full Text] [PDF]  

Dmitry Zaslavsky, Robert C. Sadoski, Sany Rajagukguk, Lois Geren, Francis Millett, Bill Durham, and Robert B. Gennis

Direct measurement of proton release by cytochrome c oxidase in solution during the FO transition
PNAS 2004 101: 10544-10547; published online before print July 9 2004, 10.1073/pnas.0401521101 [Abstract] [Full Text] [PDF]  

Janice D. Pata, William G. Stirtan, Steven W. Goldstein, and Thomas A. Steitz

Structure of HIV-1 reverse transcriptase bound to an inhibitor active against mutant reverse transcriptases resistant to other nonnucleoside inhibitors
PNAS 2004 101: 10548-10553; published online before print July 12 2004, 10.1073/pnas.0404151101 [Abstract] [Full Text] [PDF]  

Takeharu Nagai, Shuichi Yamada, Takashi Tominaga, Michinori Ichikawa, and Atsushi Miyawaki Expanded dynamic range of fluorescent indicators for Ca2+ by circularly permuted yellow fluorescent proteins PNAS 2004 101: 10554-10559; published online before print July 9 2004, 10.1073/pnas.0400417101 [Abstract] [Full Text] [PDF] [Supporting Movies] OPEN ACCESS ARTICLE

Martin J. Richer, Clairessa A. Keays, Jennifer Waterhouse, Jessey Minhas, Carl Hashimoto, and François Jean

The Spn4 gene of Drosophila encodes a potent furin-directed secretory pathway serpin
PNAS 2004 101: 10560-10565; published online before print July 9 2004, 10.1073/pnas.0401406101 [Abstract] [Full Text] [PDF]  

Masahiro Ito, Haoxing Xu, Arthur A. Guffanti, Yi Wei, Lior Zvi, David E. Clapham, and Terry A. Krulwich The voltage-gated Na+ channel NaVBP has a role in motility, chemotaxis, and pH homeostasis of an alkaliphilic Bacillus PNAS 2004 101: 10566-10571; published online before print July 8 2004, 10.1073/pnas.0402692101 [Abstract] [Full Text] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Yi-Kai Chen, Chih-Hsiang Leng, Heidi Olivares, Ming-Hui Lee, Yuan-Chih Chang, Wen-Mei Kung, Shih-Chieh Ti, Yu-Hui Lo, Andrew H.-J. Wang, Chia-Seng Chang, Douglas K. Bishop, Yi-Ping Hsueh, and Ting-Fang Wang Heterodimeric complexes of Hop2 and Mnd1 function with Dmc1 to promote meiotic homolog juxtaposition and strand assimilation PNAS 2004 101: 10572-10577; published online before print July 12 2004, 10.1073/pnas.0404195101 [Abstract] [Full Text] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Kenji Nishio, Patricia J. Anderson, X. Long Zheng, and J. Evan Sadler

Binding of platelet glycoprotein Ib to von Willebrand factor domain A1 stimulates the cleavage of the adjacent domain A2 by ADAMTS13
PNAS 2004 101: 10578-10583; published online before print July 12 2004, 10.1073/pnas.0402041101 [Abstract] [Full Text] [PDF]  

Biophysics

Magdalena I. Ivanova, Michael R. Sawaya, Mari Gingery, Antoine Attinger, and David Eisenberg

An amyloid-forming segment of 2-microglobulin suggests a molecular model for the fibril
PNAS 2004 101: 10584-10589; published online before print July 12 2004, 10.1073/pnas.0403756101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Cell Biology

Eric P. Xing and Richard M. Karp

MotifPrototyper: A Bayesian profile model for motif families
PNAS 2004 101: 10523-10528; published online before print July 13 2004, 10.1073/pnas.0403564101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Karl J. A. McCullagh, Elisa Calabria, Giorgia Pallafacchina, Stefano Ciciliot, Antonio L. Serrano, Carla Argentini, John M. Kalhovde, Terje Lømo, and Stefano Schiaffino

NFAT is a nerve activity sensor in skeletal muscle and controls activity-dependent myosin switching
PNAS 2004 101: 10590-10595; published online before print July 9 2004, 10.1073/pnas.0308035101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Wuxing Li, Changbin Chen, Ullrich Markmann-Mulisch, Ljudmilla Timofejeva, Elmon Schmelzer, Hong Ma, and Bernd Reiss

The Arabidopsis AtRAD51 gene is dispensable for vegetative development but required for meiosis
PNAS 2004 101: 10596-10601; published online before print July 12 2004, 10.1073/pnas.0404110101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Tobias N. Dechow, Laura Pedranzini, Andrea Leitch, Kenneth Leslie, William L. Gerald, Irina Linkov, and Jacqueline F. Bromberg

Requirement of matrix metalloproteinase-9 for the transformation of human mammary epithelial cells by Stat3-C
PNAS 2004 101: 10602-10607; published online before print July 12 2004, 10.1073/pnas.0404100101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Malgorzata Borowiak, Alistair N. Garratt, Torsten Wüstefeld, Michael Strehle, Christian Trautwein, and Carmen Birchmeier Met provides essential signals for liver regeneration PNAS 2004 101: 10608-10613; published online before print July 12 2004, 10.1073/pnas.0403412101 [Abstract] [Full Text] [PDF] OPEN ACCESS ARTICLE

Paramasivam Natarajan, Jiyi Wang, Zhaolin Hua, and Todd R. Graham

Drs2p-coupled aminophospholipid translocase activity in yeast Golgi membranes and relationship to in vivo function
PNAS 2004 101: 10614-10619; published online before print July 12 2004, 10.1073/pnas.0404146101 [Abstract] [Full Text] [PDF]  

Developmental Biology

Noora Kotaja, Dario De Cesare, Betina Macho, Lucia Monaco, Stefano Brancorsini, Ellen Goossens, Herman Tournaye, Anne Gansmuller, and Paolo Sassone-Corsi

Abnormal sperm in mice with targeted deletion of the act (activator of cAMP-responsive element modulator in testis) gene
PNAS 2004 101: 10620-10625; published online before print July 9 2004, 10.1073/pnas.0401947101 [Abstract] [Full Text] [PDF]  

Immo A. Hansen, Geoffrey M. Attardo, Jong-Hwa Park, Quan Peng, and Alexander S. Raikhel From the Cover: Target of rapamycin-mediated amino acid signaling in mosquito anautogeny PNAS 2004 101: 10626-10631; published online before print June 30 2004, 10.1073/pnas.0403460101 [Abstract] [Full Text] [PDF]

Ecology

Nils C. Stenseth, Amir Shabbar, Kung-Sik Chan, Stan Boutin, Eli Knispel Rueness, Dorothee Ehrich, James W. Hurrell, Ole Chr. Lingjærde, and Kjetill S. Jakobsen

Snow conditions may create an invisible barrier for lynx
PNAS 2004 101: 10632-10634; published online before print July 12 2004, 10.1073/pnas.0308674101 [Abstract] [Full Text] [PDF]  

Evolution

Martin A. Nowak, Franziska Michor, Natalia L. Komarova, and Yoh Iwasa

Evolutionary dynamics of tumor suppressor gene inactivation
PNAS 2004 101: 10635-10638; published online before print July 13 2004, 10.1073/pnas.0400747101 [Abstract] [Full Text] [PDF]  

Kevin G. Helfenbein, H. Matthew Fourcade, Rohit G. Vanjani, and Jeffrey L. Boore

The mitochondrial genome of Paraspadella gotoi is highly reduced and reveals that chaetognaths are a sister group to protostomes
PNAS 2004 101: 10639-10643; published online before print July 12 2004, 10.1073/pnas.0400941101 [Abstract] [Full Text] [PDF]  

Hans Wildschutte, David M. Wolfe, Aletheia Tamewitz, and Jeffrey G. Lawrence

Protozoan predation, diversifying selection, and the evolution of antigenic diversity in Salmonella
PNAS 2004 101: 10644-10649; published online before print July 9 2004, 10.1073/pnas.0404028101 [Abstract] [Full Text] [PDF]  

Christian Roos, Jürgen Schmitz, and Hans Zischler

Primate jumping genes elucidate strepsirrhine phylogeny
PNAS 2004 101: 10650-10654; published online before print July 12 2004, 10.1073/pnas.0403852101 [Abstract] [Full Text] [PDF] [Supporting Table]  

Genetics

Marina S. Lee and Forrest A. Spencer

Bipolar orientation of chromosomes in Saccharomyces cerevisiae is monitored by Mad1 and Mad2, but not by Mad3
PNAS 2004 101: 10655-10660; published online before print July 12 2004, 10.1073/pnas.0404102101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Shoji Fukamachi, Masazumi Sugimoto, Hiroshi Mitani, and Akihiro Shima

Somatolactin selectively regulates proliferation and morphogenesis of neural-crest derived pigment cells in medaka
PNAS 2004 101: 10661-10666; published online before print July 12 2004, 10.1073/pnas.0401278101 [Abstract] [Full Text] [PDF]  

Hideki Innan and Yuseob Kim

Pattern of polymorphism after strong artificial selection in a domestication event
PNAS 2004 101: 10667-10672; published online before print July 12 2004, 10.1073/pnas.0401720101 [Abstract] [Full Text] [PDF]  

Immunology

William Y. Go, Xuebin Liu, Michelle A. Roti, Forrest Liu, and Steffan N. Ho

NFAT5/TonEBP mutant mice define osmotic stress as a critical feature of the lymphoid microenvironment
PNAS 2004 101: 10673-10678; published online before print July 9 2004, 10.1073/pnas.0403139101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Kathrin S. Michelsen, Michelle H. Wong, Prediman K. Shah, Wenxuan Zhang, Juliana Yano, Terence M. Doherty, Shizuo Akira, Tripathi B. Rajavashisth, and Moshe Arditi

Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E
PNAS 2004 101: 10679-10684; published online before print July 12 2004, 10.1073/pnas.0403249101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Karsten Fischer, Emmanuel Scotet, Marcus Niemeyer, Heidrun Koebernick, Jens Zerrahn, Sophie Maillet, Robert Hurwitz, Mischo Kursar, Marc Bonneville, Stefan H. E. Kaufmann, and Ulrich E. Schaible

Mycobacterial phosphatidylinositol mannoside is a natural antigen for CD1d-restricted T cells
PNAS 2004 101: 10685-10690; published online before print July 8 2004, 10.1073/pnas.0403787101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Yvette E. Latchman, Spencer C. Liang, Yin Wu, Tatyana Chernova, Raymond A. Sobel, Martina Klemm, Vijay K. Kuchroo, Gordon J. Freeman, and Arlene H. Sharpe

PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells
PNAS 2004 101: 10691-10696; published online before print July 12 2004, 10.1073/pnas.0307252101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Ian D. Davis, Weisan Chen, Heather Jackson, Phillip Parente, Mark Shackleton, Wendie Hopkins, Qiyuan Chen, Nektaria Dimopoulos, Tina Luke, Roger Murphy, Andrew M. Scott, Eugene Maraskovsky, Grant McArthur, Duncan MacGregor, Sue Sturrock, Tsin Yee Tai, Simon Green, Andrew Cuthbertson, Darryl Maher, Lena Miloradovic, Susan V. Mitchell, Gerd Ritter, Achim A. Jungbluth, Yao-Tseng Chen, Sacha Gnjatic, Eric W. Hoffman, Lloyd J. Old, and Jonathan S. Cebon

Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4+ and CD8+ T cell responses in humans
PNAS 2004 101: 10697-10702; published online before print July 13 2004, 10.1073/pnas.0403572101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Medical Sciences

Jifeng Zhang, Mingui Fu, Taixing Cui, Chen Xiong, Kefeng Xu, Wei Zhong, Yan Xiao, Donna Floyd, Jian Liang, En Li, Qing Song, and Yuqing E. Chen

Selective disruption of PPAR2 impairs the development of adipose tissue and insulin sensitivity
PNAS 2004 101: 10703-10708; published online before print July 12 2004, 10.1073/pnas.0403652101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Benigno C. Valdez, Dale Henning, Rolando B. So, Jill Dixon, and Michael J. Dixon

The Treacher Collins syndrome (TCOF1) gene product is involved in ribosomal DNA gene transcription by interacting with upstream binding factor
PNAS 2004 101: 10709-10714; published online before print July 12 2004, 10.1073/pnas.0402492101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Javier A. Menendez, Luciano Vellon, Inderjit Mehmi, Bharvi P. Oza, Santiago Ropero, Ramon Colomer, and Ruth Lupu

Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells
PNAS 2004 101: 10715-10720; published online before print July 2 2004, 10.1073/pnas.0403390101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Donald C. Malins, Katie M. Anderson, Naomi K. Gilman, Virginia M. Green, Edward A. Barker, and Karl Erik Hellström From The Cover: Development of a cancer DNA phenotype prior to tumor formation PNAS 2004 101: 10721-10725; published online before print July 12 2004, 10.1073/pnas.0403888101 [Abstract] [Full Text] [PDF]

Pinar E. Coskun, M. Flint Beal, and Douglas C. Wallace

Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication
PNAS 2004 101: 10726-10731; published online before print July 9 2004, 10.1073/pnas.0403649101 [Abstract] [Full Text] [PDF]  

Yuichi Ikeda, Yasushi Imai, Hidetoshi Kumagai, Tetsuya Nosaka, Yoshihiro Morikawa, Tomoko Hisaoka, Ichiro Manabe, Koji Maemura, Takashi Nakaoka, Takeshi Imamura, Kohei Miyazono, Issei Komuro, Ryozo Nagai, and Toshio Kitamura

Vasorin, a transforming growth factor -binding protein expressed in vascular smooth muscle cells, modulates the arterial response to injury in vivo
PNAS 2004 101: 10732-10737; published online before print July 9 2004, 10.1073/pnas.0404117101 [Abstract] [Full Text] [PDF] [Supporting Information]  

David N. Criddle, Michael G. T. Raraty, John P. Neoptolemos, Alexei V. Tepikin, Ole H. Petersen, and Robert Sutton

Ethanol toxicity in pancreatic acinar cells: Mediation by nonoxidative fatty acid metabolites
PNAS 2004 101: 10738-10743; published online before print July 9 2004, 10.1073/pnas.0403431101 [Abstract] [Full Text] [PDF]  

Rainer von Coelln, Bobby Thomas, Joseph M. Savitt, Kah Leong Lim, Masayuki Sasaki, Ellen J. Hess, Valina L. Dawson, and Ted M. Dawson

Loss of locus coeruleus neurons and reduced startle in parkin null mice
PNAS 2004 101: 10744-10749; published online before print July 12 2004, 10.1073/pnas.0401297101 [Abstract] [Full Text] [PDF]  

Jianxin Xie, Hao Zhu, Kevin Larade, Annie Ladoux, Ayden Seguritan, Michelle Chu, Susumu Ito, Roderick T. Bronson, Edward H. Leiter, Chen-Yu Zhang, Evan D. Rosen, and H. Franklin Bunn

Absence of a reductase, NCB5OR, causes insulin-deficient diabetes
PNAS 2004 101: 10750-10755; published online before print July 9 2004, 10.1073/pnas.0404044101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Yuko Mochizuki, Jun He, Shashikant Kulkarni, Monica Bessler, and Philip J. Mason

Mouse dyskerin mutations affect accumulation of telomerase RNA and small nucleolar RNA, telomerase activity, and ribosomal RNA processing
PNAS 2004 101: 10756-10761; published online before print July 7 2004, 10.1073/pnas.0402560101 [Abstract] [Full Text] [PDF] [Supporting Table]  

Chunming Ding, Rossa W. K. Chiu, Tze K. Lau, Tse N. Leung, Li C. Chan, Amy Y. Y. Chan, Pimlak Charoenkwan, Ivy S. L. Ng, Hai-yang Law, Edmond S. K. Ma, Xiangmin Xu, Chanane Wanapirak, Torpong Sanguansermsri, Can Liao, Mary Anne Tan Jin Ai, David H. K. Chui, Charles R. Cantor, and Y. M. Dennis Lo

MS analysis of single-nucleotide differences in circulating nucleic acids: Application to noninvasive prenatal diagnosis
PNAS 2004 101: 10762-10767; published online before print July 9 2004, 10.1073/pnas.0403962101 [Abstract] [Full Text] [PDF]  

Sylvie G. Bernier, Douglas D. Lazarus, Edward Clark, Beth Doyle, Matthew T. Labenski, Charles D. Thompson, William F. Westlin, and Gerhard Hannig

A methionine aminopeptidase-2 inhibitor, PPI-2458, for the treatment of rheumatoid arthritis
PNAS 2004 101: 10768-10773; published online before print July 12 2004, 10.1073/pnas.0404105101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Microbiology

Theodora Hatziioannou, David Perez-Caballero, Annie Yang, Simone Cowan, and Paul D. Bieniasz

Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5
PNAS 2004 101: 10774-10779; published online before print July 12 2004, 10.1073/pnas.0402361101 [Abstract] [Full Text] [PDF]  
See Commentary on page 10496

Zuzana Keckesova, Laura M. J. Ylinen, and Greg J. Towers

The human and African green monkey TRIM5 genes encode Ref1 and Lv1 retroviral restriction factor activities
PNAS 2004 101: 10780-10785; published online before print July 12 2004, 10.1073/pnas.0402474101 [Abstract] [Full Text] [PDF]  
See Commentary on page 10496

Melvyn W. Yap, Sébastien Nisole, Clare Lynch, and Jonathan P. Stoye

Trim5 protein restricts both HIV-1 and murine leukemia virus
PNAS 2004 101: 10786-10791; published online before print July 12 2004, 10.1073/pnas.0402876101 [Abstract] [Full Text] [PDF]  
See Commentary on page 10496

Armin Baiker, Klaus Fabel, Antonio Cozzio, Leigh Zerboni, Konstanze Fabel, Marvin Sommer, Nobuko Uchida, Dongping He, Irving Weissman, and Ann M. Arvin

Varicella-zoster virus infection of human neural cells in vivo
PNAS 2004 101: 10792-10797; published online before print July 9 2004, 10.1073/pnas.0404016101 [Abstract] [Full Text] [PDF]  

Finn Terje Hegge, Paul G. Hitchen, Finn Erik Aas, Heidi Kristiansen, Cecilia Løvold, Wolfgang Egge-Jacobsen, Maria Panico, Weng Yee Leong, Victoria Bull, Mumtaz Virji, Howard R. Morris, Anne Dell, and Michael Koomey

Unique modifications with phosphocholine and phosphoethanolamine define alternate antigenic forms of Neisseria gonorrhoeae type IV pili
PNAS 2004 101: 10798-10803; published online before print July 12 2004, 10.1073/pnas.0402397101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Neuroscience

Fei Liu, Khalid Iqbal, Inge Grundke-Iqbal, Gerald W. Hart, and Cheng-Xin Gong

O-GlcNAcylation regulates phosphorylation of tau: A mechanism involved in Alzheimer's disease
PNAS 2004 101: 10804-10809; published online before print July 12 2004, 10.1073/pnas.0400348101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Dongdong Yao, Zezong Gu, Tomohiro Nakamura, Zhong-Qing Shi, Yuliang Ma, Benjamin Gaston, Lisa A. Palmer, Edward M. Rockenstein, Zhuohua Zhang, Eliezer Masliah, Takashi Uehara, and Stuart A. Lipton

Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity
PNAS 2004 101: 10810-10814; published online before print July 13 2004, 10.1073/pnas.0404161101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Stéphane Nédélec, Isabelle Foucher, Isabelle Brunet, Colette Bouillot, Alain Prochiantz, and Alain Trembleau

Emx2 homeodomain transcription factor interacts with eukaryotic translation initiation factor 4E (eIF4E) in the axons of olfactory sensory neurons
PNAS 2004 101: 10815-10820; published online before print July 9 2004, 10.1073/pnas.0403824101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Benjamin F. Cravatt, Alan Saghatelian, Edward G. Hawkins, Angela B. Clement, Michael H. Bracey, and Aron H. Lichtman

Functional disassociation of the central and peripheral fatty acid amide signaling systems
PNAS 2004 101: 10821-10826; published online before print July 9 2004, 10.1073/pnas.0401292101 [Abstract] [Full Text] [PDF]  

Lisa M. Monteggia, Michel Barrot, Craig M. Powell, Olivier Berton, Victor Galanis, Terry Gemelli, Sven Meuth, Andreas Nagy, Robert W. Greene, and Eric J. Nestler

Essential role of brain-derived neurotrophic factor in adult hippocampal function
PNAS 2004 101: 10827-10832; published online before print July 12 2004, 10.1073/pnas.0402141101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Lucia Di Marcotullio, Elisabetta Ferretti, Enrico De Smaele, Beatrice Argenti, Claudia Mincione, Francesca Zazzeroni, Rita Gallo, Laura Masuelli, Maddalena Napolitano, Marella Maroder, Andrea Modesti, Felice Giangaspero, Isabella Screpanti, Edoardo Alesse, and Alberto Gulino

REN^KCTD11 is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma
PNAS 2004 101: 10833-10838; published online before print July 12 2004, 10.1073/pnas.0400690101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Population Biology

Caroline O'F. Buckee, Katia Koelle, Matthew J. Mustard, and Sunetra Gupta

The effects of host contact network structure on pathogen diversity and strain structure
PNAS 2004 101: 10839-10844; published online before print July 9 2004, 10.1073/pnas.0402000101 [Abstract] [Full Text] [PDF]