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COMMENTARIES

Alan M. Diamond

On the road to selenocysteine
PNAS 2004 101: 13395-13396; published online before print September 7 2004, 10.1073/pnas.0405357101 [Extract] [Full Text] [PDF]  

PHYSICAL SCIENCES

Applied Physical Sciences

Chemistry

J. K. Amisha Kamal, Liang Zhao, and Ahmed H. Zewail

Ultrafast hydration dynamics in protein unfolding: Human serum albumin
PNAS 2004 101: 13411-13416; published online before print September 7 2004, 10.1073/pnas.0405724101 [Abstract] [Full Text] [PDF]  

Jesper V. Olsen and Matthias Mann Improved peptide identification in proteomics by two consecutive stages of mass spectrometric fragmentation PNAS 2004 101: 13417-13422; published online before print September 3 2004, 10.1073/pnas.0405549101 [Abstract] [Full Text] [PDF] [Supporting Tables] OPEN ACCESS ARTICLE

Engineering

Zdenek P. Bazant Inaugural Article by a Recently Elected Academy Member: Inaugural Article: Scaling theory for quasibrittle structural failure PNAS 2004 101: 13400-13407; published online before print August 2 2004, 10.1073/pnas.0404096101 [Abstract] [Full Text] [PDF]

Geology

Neil D. Opdyke and Victor J. DiVenere

The magnetic polarity stratigraphy of the Mauch Chunk Formation, Pennsylvania
PNAS 2004 101: 13423-13427; published online before print September 7 2004, 10.1073/pnas.0403786101 [Abstract] [Full Text] [PDF]  

Mathematics

Dorian Goldfeld, Alexander Lubotzky, Nikolay Nikolov, and László Pyber

Counting primes, groups, and manifolds
PNAS 2004 101: 13428-13430; published online before print September 7 2004, 10.1073/pnas.0404571101 [Abstract] [Full Text] [PDF]  

Physics

Nathan T. Moore, Rhonald C. Lua, and Alexander Y. Grosberg

Topologically driven swelling of a polymer loop
PNAS 2004 101: 13431-13435; published online before print August 31 2004, 10.1073/pnas.0403383101 [Abstract] [Full Text] [PDF]  

SOCIAL SCIENCES

BIOLOGICAL SCIENCES

Biochemistry

Anthony V. Ludlam, Brian A. Moore, and Zhaohui Xu

The crystal structure of ribosomal chaperone trigger factor from Vibrio cholerae
PNAS 2004 101: 13436-13441; published online before print September 7 2004, 10.1073/pnas.0405868101 [Abstract] [Full Text] [PDF] [Supporting Table]  

Roberto Ferrari, Claudio Rivetti, Joël Acker, and Giorgio Dieci

Distinct roles of transcription factors TFIIIB and TFIIIC in RNA polymerase III transcription reinitiation
PNAS 2004 101: 13442-13447; published online before print September 3 2004, 10.1073/pnas.0403851101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Guliang Wang and Karen M. Vasquez

Naturally occurring H-DNA-forming sequences are mutagenic in mammalian cells
PNAS 2004 101: 13448-13453; published online before print September 1 2004, 10.1073/pnas.0405116101 [Abstract] [Full Text] [PDF]  

Kathleen E. McGinness and Robert T. Sauer

Ribosomal protein S1 binds mRNA and tmRNA similarly but plays distinct roles in translation of these molecules
PNAS 2004 101: 13454-13459; published online before print August 31 2004, 10.1073/pnas.0405521101 [Abstract] [Full Text] [PDF] [Supporting Text]  

Biophysics

Ariel Fernández and R. Stephen Berry

Molecular dimension explored in evolution to promote proteomic complexity
PNAS 2004 101: 13460-13465; published online before print September 3 2004, 10.1073/pnas.0405585101 [Abstract] [Full Text] [PDF]  

Yufang Hu, Ivo Doudevski, Denise Wood, Mario Moscarello, Cynthia Husted, Claude Genain, Joseph A. Zasadzinski, and Jacob Israelachvili

Synergistic interactions of lipids and myelin basic protein
PNAS 2004 101: 13466-13471; published online before print September 7 2004, 10.1073/pnas.0405665101 [Abstract] [Full Text] [PDF]  

Hui Wang, James E. Dunning, Albert P.-H. Huang, Jacqueline A. Nyamwanda, and Daniel Branton

DNA heterogeneity and phosphorylation unveiled by single-molecule electrophoresis
PNAS 2004 101: 13472-13477; published online before print September 1 2004, 10.1073/pnas.0405568101 [Abstract] [Full Text] [PDF]  

W. Kevin Meisner and Tobin R. Sosnick From the Cover: Fast folding of a helical protein initiated by the collision of unstructured chains PNAS 2004 101: 13478-13482; published online before print September 3 2004, 10.1073/pnas.0404057101 [Abstract] [Full Text] [PDF] [Supporting Figures]

Cell Biology

Michael A. Nolan, Donner F. Babcock, Gunther Wennemuth, William Brown, Kimberly A. Burton, and G. Stanley McKnight

Sperm-specific protein kinase A catalytic subunit C₂ orchestrates cAMP signaling for male fertility
PNAS 2004 101: 13483-13488; published online before print August 31 2004, 10.1073/pnas.0405580101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Philippe P. Roux, Bryan A. Ballif, Rana Anjum, Steven P. Gygi, and John Blenis

Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase
PNAS 2004 101: 13489-13494; published online before print September 1 2004, 10.1073/pnas.0405659101 [Abstract] [Full Text] [PDF]  

Chunlin Shao, Melvyn Folkard, Barry D. Michael, and Kevin M. Prise

Targeted cytoplasmic irradiation induces bystander responses
PNAS 2004 101: 13495-13500; published online before print September 2 2004, 10.1073/pnas.0404930101 [Abstract] [Full Text] [PDF]  

Alexander Ungewickell, Michael E. Ward, Ernst Ungewickell, and Philip W. Majerus

The inositol polyphosphate 5-phosphatase Ocrl associates with endosomes that are partially coated with clathrin
PNAS 2004 101: 13501-13506; published online before print September 7 2004, 10.1073/pnas.0405664101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Regis Doyonnas, Mark A. LaBarge, Alessandra Sacco, Carol Charlton, and Helen M. Blau

Hematopoietic contribution to skeletal muscle regeneration by myelomonocytic precursors
PNAS 2004 101: 13507-13512; published online before print September 7 2004, 10.1073/pnas.0405361101 [Abstract] [Full Text] [PDF] [Supporting Text]  

Nevan J. Krogan, Kristin Baetz, Michael-Christopher Keogh, Nira Datta, Chika Sawa, Trevor C. Y. Kwok, Natalie J. Thompson, Michael G. Davey, Jeff Pootoolal, Timothy R. Hughes, Andrew Emili, Stephen Buratowski, Philip Hieter, and Jack F. Greenblatt

Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4
PNAS 2004 101: 13513-13518; published online before print September 7 2004, 10.1073/pnas.0405753101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Vishwanath Ramachandran, Marcie Williams, Tadayuki Yago, David W. Schmidtke, and Rodger P. McEver

Dynamic alterations of membrane tethers stabilize leukocyte rolling on P-selectin
PNAS 2004 101: 13519-13524; published online before print September 7 2004, 10.1073/pnas.0403608101 [Abstract] [Full Text] [PDF] [Supporting Movie]  

Developmental Biology

Zainab Jallow, Ulrike G. Jacobi, Daniel L. Weeks, Igor B. Dawid, and Gert Jan C. Veenstra

Specialized and redundant roles of TBP and a vertebrate-specific TBP paralog in embryonic gene regulation in Xenopus
PNAS 2004 101: 13525-13530; published online before print September 2 2004, 10.1073/pnas.0405536101 [Abstract] [Full Text] [PDF]  

Ecology

Evolution

Jacob L. Mueller, Daniel R. Ripoll, Charles F. Aquadro, and Mariana F. Wolfner Comparative structural modeling and inference of conserved protein classes in Drosophila seminal fluid PNAS 2004 101: 13542-13547; published online before print September 2 2004, 10.1073/pnas.0405579101 [Abstract] [Full Text] [PDF] [Supporting Figures] OPEN ACCESS ARTICLE

O. Mario Aguilar, Omar Riva, and Eitel Peltzer

Analysis of Rhizobium etli and of its symbiosis with wild Phaseolus vulgaris supports coevolution in centers of host diversification
PNAS 2004 101: 13548-13553; published online before print August 31 2004, 10.1073/pnas.0405321101 [Abstract] [Full Text] [PDF] [Supporting Table]  

Genetics

Ian Smyth, Xin Du, Martin S. Taylor, Monica J. Justice, Bruce Beutler, and Ian J. Jackson

The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis
PNAS 2004 101: 13560-13565; published online before print September 2 2004, 10.1073/pnas.0402760101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Tertius A. Hough, Debora Bogani, Michael T. Cheeseman, Jack Favor, M. Andrew Nesbit, Rajesh V. Thakker, and Mary F. Lyon

Activating calcium-sensing receptor mutation in the mouse is associated with cataracts and ectopic calcification
PNAS 2004 101: 13566-13571; published online before print September 3 2004, 10.1073/pnas.0405516101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Hyunjoo Cha-Molstad, David M. Keller, Gregory S. Yochum, Soren Impey, and Richard H. Goodman

Cell-type-specific binding of the transcription factor CREB to the cAMP-response element
PNAS 2004 101: 13572-13577; published online before print September 1 2004, 10.1073/pnas.0405587101 [Abstract] [Full Text] [PDF]  

Immunology

Ildiko Van Rhijn, David C. Young, Jin Seon Im, Steven B. Levery, Petr A. Illarionov, Gurdyal S. Besra, Steven A. Porcelli, Jenny Gumperz, Tan-Yun Cheng, and D. Branch Moody

CD1d-restricted T cell activation by nonlipidic small molecules
PNAS 2004 101: 13578-13583; published online before print September 1 2004, 10.1073/pnas.0402838101 [Abstract] [Full Text] [PDF]  

Nobuyuki Matoba, Aude Magérus, Brian C. Geyer, Yunfang Zhang, Mrinalini Muralidharan, Annette Alfsen, Charles J. Arntzen, Morgane Bomsel, and Tsafrir S. Mor

A mucosally targeted subunit vaccine candidate eliciting HIV-1 transcytosis-blocking Abs
PNAS 2004 101: 13584-13589; published online before print September 3 2004, 10.1073/pnas.0405297101 [Abstract] [Full Text] [PDF]  

Elizabeth A. Jonas, John A. Hickman, Mushtaque Chachar, Brian M. Polster, Teresa A. Brandt, Yihru Fannjiang, Iva Ivanovska, Gorka Basañez, Kathleen W. Kinnally, Joshua Zimmerberg, J. Marie Hardwick, and Leonard K. Kaczmarek

Proapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals
PNAS 2004 101: 13590-13595; published online before print September 1 2004, 10.1073/pnas.0401372101 [Abstract] [Full Text] [PDF]  

David Artis, Mei Lun Wang, Sue A. Keilbaugh, Weimian He, Mario Brenes, Gary P. Swain, Pamela A. Knight, Deborah D. Donaldson, Mitchell A. Lazar, Hugh R. P. Miller, Gerhard A. Schad, Phillip Scott, and Gary D. Wu

RELM/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract
PNAS 2004 101: 13596-13600; published online before print August 30 2004, 10.1073/pnas.0404034101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

G. Hermanson, V. Whitlow, S. Parker, K. Tonsky, D. Rusalov, M. Ferrari, P. Lalor, M. Komai, R. Mere, M. Bell, K. Brenneman, A. Mateczun, T. Evans, D. Kaslow, D. Galloway, and P. Hobart A cationic lipid-formulated plasmid DNA vaccine confers sustained antibody-mediated protection against aerosolized anthrax spores PNAS 2004 101: 13601-13606; published online before print September 1 2004, 10.1073/pnas.0405557101 [Abstract] [Full Text] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Medical Sciences

Randi B. Silver, Alicia C. Reid, Christina J. Mackins, Trevor Askwith, Ulrich Schaefer, Doris Herzlinger, and Roberto Levi

Mast cells: A unique source of renin
PNAS 2004 101: 13607-13612; published online before print September 1 2004, 10.1073/pnas.0403208101 [Abstract] [Full Text] [PDF]  

Masahiro Aoki, Hao Jiang, and Peter K. Vogt

Proteasomal degradation of the FoxO1 transcriptional regulator in cells transformed by the P3k and Akt oncoproteins
PNAS 2004 101: 13613-13617; published online before print September 1 2004, 10.1073/pnas.0405454101 [Abstract] [Full Text] [PDF]  

Luiz F. Zerbini, Yihong Wang, Akos Czibere, Ricardo G. Correa, Je-Yoel Cho, Kosei Ijiri, Wanjang Wei, Marie Joseph, Xuesong Gu, Franck Grall, Mary B. Goldring, Jin-Rong Zhou, and Towia A. Libermann

NF-B-mediated repression of growth arrest- and DNA-damage-inducible proteins 45 and is essential for cancer cell survival
PNAS 2004 101: 13618-13623; published online before print September 7 2004, 10.1073/pnas.0402069101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Young Lee, R. Haris Naseem, Laurence Duplomb, Byung-Hyun Park, Daniel J. Garry, James A. Richardson, Jean E. Schaffer, and Roger H. Unger

Hyperleptinemia prevents lipotoxic cardiomyopathy in acyl CoA synthase transgenic mice
PNAS 2004 101: 13624-13629; published online before print September 3 2004, 10.1073/pnas.0405499101 [Abstract] [Full Text] [PDF]  

Microbiology

Peng Zhang, Bruno B. Chomel, Maureen K. Schau, Jeanna S. Goo, Sara Droz, Karen L. Kelminson, Smitha S. George, Nicholas W. Lerche, and Jane E. Koehler

A family of variably expressed outer-membrane proteins (Vomp) mediates adhesion and autoaggregation in Bartonella quintana
PNAS 2004 101: 13630-13635; published online before print September 3 2004, 10.1073/pnas.0405284101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Andrew T. Dufresne and Matthias Gromeier

A nonpolio enterovirus with respiratory tropism causes poliomyelitis in intercellular adhesion molecule 1 transgenic mice
PNAS 2004 101: 13636-13641; published online before print September 7 2004, 10.1073/pnas.0403998101 [Abstract] [Full Text] [PDF]  

Kevin Pethe, Dana L. Swenson, Sylvie Alonso, Jennifer Anderson, Carren Wang, and David G. Russell Isolation of Mycobacterium tuberculosis mutants defective in the arrest of phagosome maturation PNAS 2004 101: 13642-13647; published online before print August 31 2004, 10.1073/pnas.0401657101 [Abstract] [Full Text] [PDF] OPEN ACCESS ARTICLE

Neuroscience

Claudia Erbel-Sieler, Carol Dudley, Yudong Zhou, Xinle Wu, Sandi Jo Estill, Tina Han, Ramon Diaz-Arrastia, Eric W. Brunskill, S. Steven Potter, and Steven L. McKnight

Behavioral and regulatory abnormalities in mice deficient in the NPAS1 and NPAS3 transcription factors
PNAS 2004 101: 13648-13653; published online before print September 3 2004, 10.1073/pnas.0405310101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Sotaro Ooto, Tadamichi Akagi, Ryoichiro Kageyama, Joe Akita, Michiko Mandai, Yoshihito Honda, and Masayo Takahashi

Potential for neural regeneration after neurotoxic injury in the adult mammalian retina
PNAS 2004 101: 13654-13659; published online before print September 7 2004, 10.1073/pnas.0402129101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

Stephen R. Thom, Veena M. Bhopale, Donald Fisher, Jie Zhang, and Phyllis Gimotty From the Cover: Delayed neuropathology after carbon monoxide poisoning is immune-mediated PNAS 2004 101: 13660-13665; published online before print September 1 2004, 10.1073/pnas.0405642101 [Abstract] [Full Text] [PDF]

Nancy G. Forger, Greta J. Rosen, Elizabeth M. Waters, Dena Jacob, Richard B. Simerly, and Geert J. de Vries

Deletion of Bax eliminates sex differences in the mouse forebrain
PNAS 2004 101: 13666-13671; published online before print September 1 2004, 10.1073/pnas.0404644101 [Abstract] [Full Text] [PDF]  

Pharmacology

Chris Hague, Michelle A. Uberti, Zhongjian Chen, Cristina F. Bush, Seth V. Jones, Kerry J. Ressler, Randy A. Hall, and Kenneth P. Minneman

Olfactory receptor surface expression is driven by association with the ₂-adrenergic receptor
PNAS 2004 101: 13672-13676; published online before print September 3 2004, 10.1073/pnas.0403854101 [Abstract] [Full Text] [PDF]  

George D. Prell, Giorgio P. Martinelli, Gay R. Holstein, Jasenka Matulic-Adamic, Kyoichi A. Watanabe, Susan L. F. Chan, Noel G. Morgan, Musa A. Haxhiu, and Paul Ernsberger

Imidazoleacetic acid-ribotide: An endogenous ligand that stimulates imidazol(in)e receptors
PNAS 2004 101: 13677-13682; published online before print September 13 2004, 10.1073/pnas.0404846101 [Abstract] [Full Text] [PDF]  

Andrew Webb, Richard Bond, Peter McLean, Rakesh Uppal, Nigel Benjamin, and Amrita Ahluwalia

Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia–reperfusion damage
PNAS 2004 101: 13683-13688; published online before print September 3 2004, 10.1073/pnas.0402927101 [Abstract] [Full Text] [PDF]  

Physiology

Leah S. Torrie, Jonathan C. Radford, Tony D. Southall, Laura Kean, Andrew J. Dinsmore, Shireen A. Davies, and Julian A. T. Dow

Resolution of the insect ouabain paradox
PNAS 2004 101: 13689-13693; published online before print September 3 2004, 10.1073/pnas.0403087101 [Abstract] [Full Text] [PDF]  

CORRECTIONS

Correction for Zhou et al., Association between climate variability and malaria epidemics in the East African highlands, PNAS 2004 101:2375-2380 [Extract] [Full Text] [PDF]  

Correction for Farrell et al., Inhibition of Epstein-Barr virus-induced growth proliferation by a nuclear antigen EBNA2-TAT peptide, PNAS 2004 101:4625-4630 [Extract] [Full Text] [PDF]  

Correction for Tao et al., Cardioprotective effects of thioredoxin in myocardial ischemia and reperfusion: Role of S-nitrosation, PNAS 2004 101:11471-11476 [Extract] [Full Text] [PDF]