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COMMENTARIES

James A. Spudich

Two important polymers cross paths
PNAS 2004 101: 15825-15826; published online before print November 2 2004, 10.1073/pnas.0406932101 [Extract] [Full Text] [PDF]  
See companion article on page 15876

PERSPECTIVES

Robert B. Jackson and William H. Schlesinger

Curbing the U.S. carbon deficit
PNAS 2004 101: 15827-15829; published online before print October 28 2004, 10.1073/pnas.0403631101 [Abstract] [Full Text] [PDF]  

PHYSICAL SCIENCES

Applied Mathematics

G. Lin, C. H. Su, and G. E. Karniadakis

The stochastic piston problem
PNAS 2004 101: 15840-15845; published online before print October 28 2004, 10.1073/pnas.0405889101 [Abstract] [Full Text] [PDF] [Supporting Text]  

Applied Physical Sciences

Luis Cruz, Daniel L. Roe, Brigita Urbanc, Howard Cabral, H. E. Stanley, and Douglas L. Rosene

Age-related reduction in microcolumnar structure in area 46 of the rhesus monkey correlates with behavioral decline
PNAS 2004 101: 15846-15851; published online before print November 1 2004, 10.1073/pnas.0407002101 [Abstract] [Full Text] [PDF]  

Stefan Gheorghiu and Marc-Olivier Coppens

Heterogeneity explains features of "anomalous" thermodynamics and statistics
PNAS 2004 101: 15852-15856; published online before print October 28 2004, 10.1073/pnas.0407191101 [Abstract] [Full Text] [PDF]  

Chemistry

John P. Dumbacher, Avit Wako, Scott R. Derrickson, Allan Samuelson, Thomas F. Spande, and John W. Daly

Melyrid beetles (Choresine): A putative source for the batrachotoxin alkaloids found in poison-dart frogs and toxic passerine birds
PNAS 2004 101: 15857-15860; published online before print November 1 2004, 10.1073/pnas.0407197101 [Abstract] [Full Text] [PDF]  

Computer Sciences

Engineering

Geophysics

Wendy L. Mao, Guoyin Shen, Vitali B. Prakapenka, Yue Meng, Andrew J. Campbell, Dion L. Heinz, Jinfu Shu, Russell J. Hemley, and Ho-kwang Mao

Ferromagnesian postperovskite silicates in the D'' layer of the Earth
PNAS 2004 101: 15867-15869; published online before print November 1 2004, 10.1073/pnas.0407135101 [Abstract] [Full Text] [PDF]  

SOCIAL SCIENCES

Psychology

BIOLOGICAL SCIENCES

Biochemistry

Frederick Berkovitch, Elham Behshad, Kuo-Hsiang Tang, Eva A. Enns, Perry A. Frey, and Catherine L. Drennan

A locking mechanism preventing radical damage in the absence of substrate, as revealed by the x-ray structure of lysine 5,6-aminomutase
PNAS 2004 101: 15870-15875; published online before print October 28 2004, 10.1073/pnas.0407074101 [Abstract] [Full Text] [PDF] [Supporting Figure]  

María R. Gómez-García and Arthur Kornberg

Formation of an actin-like filament concurrent with the enzymatic synthesis of inorganic polyphosphate
PNAS 2004 101: 15876-15880; published online before print October 20 2004, 10.1073/pnas.0406923101 [Abstract] [Full Text] [PDF]  
See Commentary on page 15825

Madhavan R. Buddha, Kim M. Keery, and Brian R. Crane

An unusual tryptophanyl tRNA synthetase interacts with nitric oxide synthase in Deinococcus radiodurans
PNAS 2004 101: 15881-15886; published online before print November 1 2004, 10.1073/pnas.0405483101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Swarnalatha Y. Reddy and Thomas C. Bruice

Mechanisms of ammonia activation and ammonium ion inhibition of quinoprotein methanol dehydrogenase: A computational approach
PNAS 2004 101: 15887-15892; published online before print November 1 2004, 10.1073/pnas.0407209101 [Abstract] [Full Text] [PDF]  

Mikael J. Lindberg, Johanna Normark, Arne Holmgren, and Mikael Oliveberg

Folding of human superoxide dismutase: Disulfide reduction prevents dimerization and produces marginally stable monomers
PNAS 2004 101: 15893-15898; published online before print November 2 2004, 10.1073/pnas.0403979101 [Abstract] [Full Text] [PDF]  

Scott J. Bornheimer, Mano R. Maurya, Marilyn Gist Farquhar, and Shankar Subramaniam Computational modeling reveals how interplay between components of a GTPase-cycle module regulates signal transduction PNAS 2004 101: 15899-15904; published online before print November 1 2004, 10.1073/pnas.0407009101 [Abstract] [Full Text] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Biophysics

Jörg Wiedenmann, Sergey Ivanchenko, Franz Oswald, Florian Schmitt, Carlheinz Röcker, Anya Salih, Klaus-Dieter Spindler, and G. Ulrich Nienhaus

EosFP, a fluorescent marker protein with UV-inducible green-to-red fluorescence conversion
PNAS 2004 101: 15905-15910; published online before print October 25 2004, 10.1073/pnas.0403668101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Christian Laforsch, Wilfred Ngwa, Wolfgang Grill, and Ralph Tollrian

An acoustic microscopy technique reveals hidden morphological defenses in Daphnia
PNAS 2004 101: 15911-15914; published online before print November 1 2004, 10.1073/pnas.0404860101 [Abstract] [Full Text] [PDF]  

Deguo Du, Yongjin Zhu, Cheng-Yen Huang, and Feng Gai

Understanding the key factors that control the rate of -hairpin folding
PNAS 2004 101: 15915-15920; published online before print November 1 2004, 10.1073/pnas.0405904101 [Abstract] [Full Text] [PDF]  

J. Deich, E. M. Judd, H. H. McAdams, and W. E. Moerner

Visualization of the movement of single histidine kinase molecules in live Caulobacter cells
PNAS 2004 101: 15921-15926; published online before print November 2 2004, 10.1073/pnas.0404200101 [Abstract] [Full Text] [PDF]  

Cell Biology

Sara Cipolat, Olga Martins de Brito, Barbara Dal Zilio, and Luca Scorrano

OPA1 requires mitofusin 1 to promote mitochondrial fusion
PNAS 2004 101: 15927-15932; published online before print October 27 2004, 10.1073/pnas.0407043101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Martijn J. Moné, Tytus Bernas, Christoffel Dinant, Feliks A. Goedvree, Erik M. M. Manders, Marcel Volker, Adriaan B. Houtsmuller, Jan H. J. Hoeijmakers, Wim Vermeulen, and Roel van Driel

In vivo dynamics of chromatin-associated complex formation in mammalian nucleotide excision repair
PNAS 2004 101: 15933-15937; published online before print November 1 2004, 10.1073/pnas.0403664101 [Abstract] [Full Text] [PDF]  

I. Brust-Mascher, G. Civelekoglu-Scholey, M. Kwon, A. Mogilner, and J. M. Scholey Model for anaphase B: Role of three mitotic motors in a switch from poleward flux to spindle elongation PNAS 2004 101: 15938-15943; published online before print November 2 2004, 10.1073/pnas.0407044101 [Abstract] [Full Text] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Shakil A. Khan, Kwangho Lee, Khalid M. Minhas, Daniel R. Gonzalez, Shubha V. Y. Raju, Ankit D. Tejani, Dechun Li, Dan E. Berkowitz, and Joshua M. Hare From the Cover: Neuronal nitric oxide synthase negatively regulates xanthine oxidoreductase inhibition of cardiac excitation-contraction coupling PNAS 2004 101: 15944-15948; published online before print October 14 2004, 10.1073/pnas.0404136101 [Abstract] [Full Text] [PDF]

Developmental Biology

Kevin K. Lin, Darya Chudova, G. Wesley Hatfield, Padhraic Smyth, and Bogi Andersen Identification of hair cycle-associated genes from time-course gene expression profile data by using replicate variance PNAS 2004 101: 15955-15960; published online before print November 1 2004, 10.1073/pnas.0407114101 [Abstract] [Full Text] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Chiann-mun Chen, Walter Strapps, Andrew Tomlinson, and Gary Struhl

Evidence that the cysteine-rich domain of Drosophila Frizzled family receptors is dispensable for transducing Wingless
PNAS 2004 101: 15961-15966; published online before print October 28 2004, 10.1073/pnas.0407103101 [Abstract] [Full Text] [PDF]  

Evolution

Sofia Berlin and Hans Ellegren

Chicken W: A genetically uniform chromosome in a highly variable genome
PNAS 2004 101: 15967-15969; published online before print November 1 2004, 10.1073/pnas.0405126101 [Abstract] [Full Text] [PDF] [Supporting Table]  

Andrea S. Aspbury and Caitlin R. Gabor

Discriminating males alter sperm production between species
PNAS 2004 101: 15970-15973; published online before print November 1 2004, 10.1073/pnas.0405653101 [Abstract] [Full Text] [PDF]  

Genetics

Kyungjae Myung, Stephanie Smith, and Richard D. Kolodner

Mitotic checkpoint function in the formation of gross chromosomal rearrangements in Saccharomyces cerevisiae
PNAS 2004 101: 15980-15985; published online before print October 28 2004, 10.1073/pnas.0407010101 [Abstract] [Full Text] [PDF]  

Christopher N. Topp, Cathy X. Zhong, and R. Kelly Dawe

Centromere-encoded RNAs are integral components of the maize kinetochore
PNAS 2004 101: 15986-15991; published online before print October 28 2004, 10.1073/pnas.0407154101 [Abstract] [Full Text] [PDF]  

Nicola S. Fearnhead, Jennifer L. Wilding, Bruce Winney, Susan Tonks, Sylvia Bartlett, David C. Bicknell, Ian P. M. Tomlinson, Neil J. McC. Mortensen, and Walter F. Bodmer

Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas
PNAS 2004 101: 15992-15997; published online before print November 1 2004, 10.1073/pnas.0407187101 [Abstract] [Full Text] [PDF] [Supporting Tables]  

Blanka Rogina and Stephen L. Helfand

Sir2 mediates longevity in the fly through a pathway related to calorie restriction
PNAS 2004 101: 15998-16003; published online before print November 1 2004, 10.1073/pnas.0404184101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Immunology

Dong U. Lee and Anjana Rao

Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: A target for STAT6 but not GATA3
PNAS 2004 101: 16010-16015; published online before print October 26 2004, 10.1073/pnas.0407031101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Medical Sciences

Ori Brenner, Ditsa Levanon, Varda Negreanu, Olga Golubkov, Ofer Fainaru, Eilon Woolf, and Yoram Groner

Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia
PNAS 2004 101: 16016-16021; published online before print October 28 2004, 10.1073/pnas.0407180101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Joseph Lotem, Hila Benjamin, Dvir Netanely, Eytan Domany, and Leo Sachs

Induction in myeloid leukemic cells of genes that are expressed in different normal tissues
PNAS 2004 101: 16022-16027; published online before print October 25 2004, 10.1073/pnas.0406966101 [Abstract] [Full Text] [PDF] [Supporting Tables]  

Daniel G. Anderson, Weidan Peng, Akin Akinc, Naushad Hossain, Anat Kohn, Robert Padera, Robert Langer, and Janet A. Sawicki From the Cover: A polymer library approach to suicide gene therapy for cancer PNAS 2004 101: 16028-16033; published online before print November 1 2004, 10.1073/pnas.0407218101 [Abstract] [Full Text] [PDF] [Supporting Information]

Microbiology

M. Schuster, M. L. Urbanowski, and E. P. Greenberg Inaugural Article by a Recently Elected Academy Member: Inaugural Article: Promoter specificity in Pseudomonas aeruginosa quorum sensing revealed by DNA binding of purified LasR PNAS 2004 101: 15833-15839; published online before print October 25 2004, 10.1073/pnas.0407229101 [Abstract] [Full Text] [PDF]

G. A. Smith, L. Pomeranz, S. P. Gross, and L. W. Enquist

Local modulation of plus-end transport targets herpesvirus entry and egress in sensory axons
PNAS 2004 101: 16034-16039; published online before print October 25 2004, 10.1073/pnas.0404686101 [Abstract] [Full Text] [PDF] [Supporting Movies]  

Ivan Y. Khudyakov and James W. Golden

Different functions of HetR, a master regulator of heterocyst differentiation in Anabaena sp. PCC 7120, can be separated by mutation
PNAS 2004 101: 16040-16045; published online before print November 1 2004, 10.1073/pnas.0405572101 [Abstract] [Full Text] [PDF]  

Neuroscience

Luis Cruz, Daniel L. Roe, Brigita Urbanc, Howard Cabral, H. E. Stanley, and Douglas L. Rosene

Age-related reduction in microcolumnar structure in area 46 of the rhesus monkey correlates with behavioral decline
PNAS 2004 101: 15846-15851; published online before print November 1 2004, 10.1073/pnas.0407002101 [Abstract] [Full Text] [PDF]  

Lucia Carvelli, Paul W. McDonald, Randy D. Blakely, and Louis J. DeFelice

Dopamine transporters depolarize neurons by a channel mechanism
PNAS 2004 101: 16046-16051; published online before print November 1 2004, 10.1073/pnas.0403299101 [Abstract] [Full Text] [PDF]  

Charles L. Limoli, Radoslaw Rola, Erich Giedzinski, Sailaja Mantha, Ting-Ting Huang, and John R. Fike

Cell-density-dependent regulation of neural precursor cell function
PNAS 2004 101: 16052-16057; published online before print November 2 2004, 10.1073/pnas.0407065101 [Abstract] [Full Text] [PDF]  

Takaomi Sakai, Takuya Tamura, Toshihiro Kitamoto, and Yoshiaki Kidokoro

A clock gene, period, plays a key role in long-term memory formation in Drosophila
PNAS 2004 101: 16058-16063; published online before print November 2 2004, 10.1073/pnas.0401472101 [Abstract] [Full Text] [PDF] [Supporting Information]  

Tiago V. Maia and James L. McClelland From the Cover: A reexamination of the evidence for the somatic marker hypothesis: What participants really know in the Iowa gambling task PNAS 2004 101: 16075-16080; published online before print October 22 2004, 10.1073/pnas.0406666101 [Abstract] [Full Text] [PDF] [Supporting Information]

Physiology

Eric E. Zhang, Emilie Chapeau, Kazuki Hagihara, and Gen-Sheng Feng

Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
PNAS 2004 101: 16064-16069; published online before print November 1 2004, 10.1073/pnas.0405041101 [Abstract] [Full Text] [PDF] [Supporting Figures]  

Plant Biology

M. E. Nasrallah, P. Liu, S. Sherman-Broyles, N. A. Boggs, and J. B. Nasrallah

Natural variation in expression of self-incompatibility in Arabidopsis thaliana: Implications for the evolution of selfing
PNAS 2004 101: 16070-16074; published online before print October 25 2004, 10.1073/pnas.0406970101 [Abstract] [Full Text] [PDF] [Supporting Information]  

CORRECTIONS

Correction for Fersht, Relationship of Leffler (Brønsted) values and protein folding values to position of transition-state structures on reaction coordinates, PNAS 2004 101:14338-14342 [Extract] [Full Text] [PDF]  

Correction for Willer et al., Targeted disruption of the Walker–Warburg syndrome gene Pomt1 in mouse results in embryonic lethality, PNAS 2004 101:14126-14131 [Extract] [Full Text] [PDF]  

Correction for Thiele et al., Contribution of inhibitory mechanisms to direction selectivity and response normalization in macaque middle temporal area, PNAS 2004 101:9810-9815 [Extract] [Full Text] [PDF]  

Retraction for Chandok et al., Suppression of pathogen-inducible NO synthase (iNOS) activity in tomato increases susceptibility to Pseudomonas syringae, PNAS 2004 101:8239-8244 [Extract] [Full Text] [PDF]