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IN THIS ISSUE

This Week in PNAS
PNAS 2005 102: 5637-5638. [Full Text] [Figures Only] [PDF]  

COMMENTARIES

Urs F. Greber

Viral trafficking violations in axons: The herpesvirus case
PNAS 2005 102: 5639-5640; published online before print April 12 2005, 10.1073/pnas.0501696102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 5832

Michele Vendruscolo and Christopher M. Dobson

A glimpse at the organization of the protein universe
PNAS 2005 102: 5641-5642; published online before print April 12 2005, 10.1073/pnas.0500274102 [Extract] [Full Text] [Figures Only] [PDF]  

Markus A. Ruegg

Organization of synaptic myonuclei by Syne proteins and their role during the formation of the nerve–muscle synapse
PNAS 2005 102: 5643-5644; published online before print April 12 2005, 10.1073/pnas.0501516102 [Extract] [Full Text] [Figures Only] [PDF]  

Barbara L. Hempstead

Coupling neurotrophins to cell migration through selective guanine nucleotide exchange factor activation
PNAS 2005 102: 5645-5646; published online before print April 12 2005, 10.1073/pnas.0501718102 [Extract] [Full Text] [Figures Only] [PDF]  

PHYSICAL SCIENCES

Applied Mathematics

Applied Physical Sciences

F. Remacle, J. R. Heath, and R. D. Levine

Electrical addressing of confined quantum systems for quasiclassical computation and finite state logic machines
PNAS 2005 102: 5653-5658; published online before print April 8 2005, 10.1073/pnas.0501623102 [Abstract] [Full Text] [Figures Only] [PDF]  

Chemistry

Mathematics

Mitya Boyarchenko and Sergei Levendorskii

Generalizations of the classical Weyl and Colin de Verdière's formulas and the orbit method
PNAS 2005 102: 5663-5668; published online before print April 12 2005, 10.1073/pnas.0500444102 [Abstract] [Full Text] [PDF]  

Physics

Paolo De Gregorio, Aonghus Lawlor, Phil Bradley, and Kenneth A. Dawson

Exact solution of a jamming transition: Closed equations for a bootstrap percolation problem
PNAS 2005 102: 5669-5673; published online before print April 4 2005, 10.1073/pnas.0408756102 [Abstract] [Full Text] [Figures Only] [PDF]  

SOCIAL SCIENCES

BIOLOGICAL SCIENCES

Anthropology

Applied Biological Sciences

Mini Thomas, James J. Lu, Qing Ge, Chengcheng Zhang, Jianzhu Chen, and Alexander M. Klibanov

Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung
PNAS 2005 102: 5679-5684; published online before print April 11 2005, 10.1073/pnas.0502067102 [Abstract] [Full Text] [Figures Only] [PDF]  

Biochemistry

Daisy W. Leung and Michael K. Rosen

The nucleotide switch in Cdc42 modulates coupling between the GTPase-binding and allosteric equilibria of Wiskott–Aldrich syndrome protein
PNAS 2005 102: 5685-5690; published online before print April 8 2005, 10.1073/pnas.0406472102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Karuppiah Chockalingam, Zhilei Chen, John A. Katzenellenbogen, and Huimin Zhao

Directed evolution of specific receptor–ligand pairs for use in the creation of gene switches
PNAS 2005 102: 5691-5696; published online before print April 5 2005, 10.1073/pnas.0409206102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Hideaki Saeki, Keita Ohsumi, Hitoshi Aihara, Takashi Ito, Susumu Hirose, Kiyoe Ura, and Yasufumi Kaneda Linker histone variants control chromatin dynamics during early embryogenesis PNAS 2005 102: 5697-5702; published online before print April 8 2005, 10.1073/pnas.0409824102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures] OPEN ACCESS ARTICLE

Alexandra Beilina, Marcel Van Der Brug, Rili Ahmad, Sashi Kesavapany, David W. Miller, Gregory A. Petsko, and Mark R. Cookson

Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability
PNAS 2005 102: 5703-5708; published online before print April 11 2005, 10.1073/pnas.0500617102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Allan Doctor, Ruth Platt, Mary Lynn Sheram, Anne Eischeid, Timothy McMahon, Thomas Maxey, Joseph Doherty, Mark Axelrod, Jaclyn Kline, Matthew Gurka, Andrew Gow, and Benjamin Gaston

Hemoglobin conformation couples erythrocyte S-nitrosothiol content to O₂ gradients
PNAS 2005 102: 5709-5714; published online before print April 11 2005, 10.1073/pnas.0407490102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Biophysics

Ewan R. G. Main, Katherine Stott, Sophie E. Jackson, and Lynne Regan

Local and long-range stability in tandemly arrayed tetratricopeptide repeats
PNAS 2005 102: 5721-5726; published online before print April 11 2005, 10.1073/pnas.0404530102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Hongtao Zhao, Joy Joseph, Henry M. Fales, Edward A. Sokoloski, Rodney L. Levine, Jeannette Vasquez-Vivar, and B. Kalyanaraman

Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence
PNAS 2005 102: 5727-5732; published online before print April 11 2005, 10.1073/pnas.0501719102 [Abstract] [Full Text] [Figures Only] [PDF]  

Cell Biology

Jianxiong Li, Alexander Krichevsky, Manjusha Vaidya, Tzvi Tzfira, and Vitaly Citovsky

Uncoupling of the functions of the Arabidopsis VIP1 protein in transient and stable plant genetic transformation by Agrobacterium
PNAS 2005 102: 5733-5738; published online before print April 11 2005, 10.1073/pnas.0404118102 [Abstract] [Full Text] [Figures Only] [PDF]  

Tadahide Izumi, David B. Brown, C. V. Naidu, Kishor K. Bhakat, Mark A. MacInnes, Hiroshi Saito, David J. Chen, and Sankar Mitra

Two essential but distinct functions of the mammalian abasic endonuclease
PNAS 2005 102: 5739-5743; published online before print April 11 2005, 10.1073/pnas.0500986102 [Abstract] [Full Text] [Figures Only] [PDF]  

Developmental Biology

Balaraj B. Menon, Nayan J. Sarma, Satish Pasula, Stephen J. Deminoff, Kristine A. Willis, Kellie E. Barbara, Brenda Andrews, and George M. Santangelo Reverse recruitment: The Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation PNAS 2005 102: 5749-5754; published online before print April 7 2005, 10.1073/pnas.0501768102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Juxiang Yang, Sergey Medvedev, Junying Yu, Linda C. Tang, Julio E. Agno, Martin M. Matzuk, Richard M. Schultz, and Norman B. Hecht

Absence of the DNA-/RNA-binding protein MSY2 results in male and female infertility
PNAS 2005 102: 5755-5760; published online before print April 11 2005, 10.1073/pnas.0408718102 [Abstract] [Full Text] [Figures Only] [PDF]  

Ecology

Nicolas Loeuille and Michel Loreau

Evolutionary emergence of size-structured food webs
PNAS 2005 102: 5761-5766; published online before print April 11 2005, 10.1073/pnas.0408424102 [Abstract] [Full Text] [Figures Only] [PDF]  

Evolution

Wendy E. Grus, Peng Shi, Ya-ping Zhang, and Jianzhi Zhang

Dramatic variation of the vomeronasal pheromone receptor gene repertoire among five orders of placental and marsupial mammals
PNAS 2005 102: 5767-5772; published online before print March 24 2005, 10.1073/pnas.0501589102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Scott William Roy and Walter Gilbert

Rates of intron loss and gain: Implications for early eukaryotic evolution
PNAS 2005 102: 5773-5778; published online before print April 12 2005, 10.1073/pnas.0500383102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Chaoying He and Heinz Saedler

Heterotopic expression of MPF2 is the key to the evolution of the Chinese lantern of Physalis, a morphological novelty in Solanaceae
PNAS 2005 102: 5779-5784; published online before print April 11 2005, 10.1073/pnas.0501877102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Charles F. Baer, Frank Shaw, Catherine Steding, Margaret Baumgartner, Alicia Hawkins, Andrew Houppert, Nicole Mason, Marissa Reed, Kevin Simonelic, Wayne Woodard, and Michael Lynch

Comparative evolutionary genetics of spontaneous mutations affecting fitness in rhabditid nematodes
PNAS 2005 102: 5785-5790; published online before print April 4 2005, 10.1073/pnas.0406056102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  

Charles B. Kimmel, Bonnie Ullmann, Charline Walker, Catherine Wilson, Mark Currey, Patrick C. Phillips, Michael A. Bell, John H. Postlethwait, and William A. Cresko Evolution and development of facial bone morphology in threespine sticklebacks PNAS 2005 102: 5791-5796; published online before print April 11 2005, 10.1073/pnas.0408533102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Genetics

Yuko Tonami, Hiroshi Murakami, Katsuhiko Shirahige, and Makoto Nakanishi

A checkpoint control linking meiotic S phase and recombination initiation in fission yeast
PNAS 2005 102: 5797-5801; published online before print April 1 2005, 10.1073/pnas.0407236102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Diane P. Genereux, Brooks E. Miner, Carl T. Bergstrom, and Charles D. Laird

A population-epigenetic model to infer site-specific methylation rates from double-stranded DNA methylation patterns
PNAS 2005 102: 5802-5807; published online before print April 12 2005, 10.1073/pnas.0502036102 [Abstract] [Full Text] [Figures Only] [PDF]  

Immunology

Kavitha Viswanathan and Firdaus S. Dhabhar

Stress-induced enhancement of leukocyte trafficking into sites of surgery or immune activation
PNAS 2005 102: 5808-5813; published online before print April 7 2005, 10.1073/pnas.0501650102 [Abstract] [Full Text] [Figures Only] [PDF]  

Medical Sciences

Scott Q. Harper, Patrick D. Staber, Xiaohua He, Steven L. Eliason, Inês H. Martins, Qinwen Mao, Linda Yang, Robert M. Kotin, Henry L. Paulson, and Beverly L. Davidson From the Cover: RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model PNAS 2005 102: 5820-5825; published online before print April 5 2005, 10.1073/pnas.0501507102 [Abstract] [Full Text] [Figures Only] [PDF]

Rohini Kuner, Anthony J. Groom, Iris Bresink, Hans-Christian Kornau, Vanya Stefovska, Gerald Müller, Bettina Hartmann, Karsten Tschauner, Stefan Waibel, Albert C. Ludolph, Chrysanthy Ikonomidou, Peter H. Seeburg, and Lechoslaw Turski

Late-onset motoneuron disease caused by a functionally modified AMPA receptor subunit
PNAS 2005 102: 5826-5831; published online before print April 12 2005, 10.1073/pnas.0501316102 [Abstract] [Full Text] [Figures Only] [PDF]  

Microbiology

Yu Liang, Alexei Kurakin, and Bernard Roizman

Herpes simplex virus 1 infected cell protein 0 forms a complex with CIN85 and Cbl and mediates the degradation of EGF receptor from cell surfaces
PNAS 2005 102: 5838-5843; published online before print April 11 2005, 10.1073/pnas.0501253102 [Abstract] [Full Text] [Figures Only] [PDF]  

Caroline E. Lilley, Christian T. Carson, Alysson R. Muotri, Fred H. Gage, and Matthew D. Weitzman DNA repair proteins affect the lifecycle of herpes simplex virus 1 PNAS 2005 102: 5844-5849; published online before print April 11 2005, 10.1073/pnas.0501916102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures] OPEN ACCESS ARTICLE

Neuroscience

Hartmut Schmidt, Beat Schwaller, and Jens Eilers

Calbindin D28k targets myo-inositol monophosphatase in spines and dendrites of cerebellar Purkinje neurons
PNAS 2005 102: 5850-5855; published online before print April 4 2005, 10.1073/pnas.0407855102 [Abstract] [Full Text] [Figures Only] [PDF]  

Flobert Y. Tanga, Nancy Nutile-McMenemy, and Joyce A. DeLeo

The CNS role of Toll-like receptor 4 in innate neuroimmunity and painful neuropathy
PNAS 2005 102: 5856-5861; published online before print April 4 2005, 10.1073/pnas.0501634102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Bin Zhang, Jianghe Zheng, Ichiro Watanabe, Ichiro Maruko, Hua Bi, Earl L. Smith, III, and Yuzo Chino Delayed maturation of receptive field center/surround mechanisms in V2 PNAS 2005 102: 5862-5867; published online before print April 11 2005, 10.1073/pnas.0501815102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

David Cai, Aaditya V. Rangan, and David W. McLaughlin

Architectural and synaptic mechanisms underlying coherent spontaneous activity in V1
PNAS 2005 102: 5868-5873; published online before print April 12 2005, 10.1073/pnas.0501913102 [Abstract] [Full Text] [Figures Only] [PDF]  

Masaaki Sato, Kazunori Suzuki, Hiroshi Yamazaki, and Shigetada Nakanishi

A pivotal role of calcineurin signaling in development and maturation of postnatal cerebellar granule cells
PNAS 2005 102: 5874-5879; published online before print April 4 2005, 10.1073/pnas.0501972102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Physiology

Plant Biology

Kamila Rzeznicka, Caroline J. Walker, Tomas Westergren, C. Gamini Kannangara, Diter von Wettstein, Sabeeha Merchant, Simon P. Gough, and Mats Hansson

Xantha-l encodes a membrane subunit of the aerobic Mg-protoporphyrin IX monomethyl ester cyclase involved in chlorophyll biosynthesis
PNAS 2005 102: 5886-5891; published online before print April 11 2005, 10.1073/pnas.0501784102 [Abstract] [Full Text] [Figures Only] [PDF]  

Thomas N. Taylor, Hans Kerp, and Hagen Hass From the Cover: Life history biology of early land plants: Deciphering the gametophyte phase PNAS 2005 102: 5892-5897; published online before print April 4 2005, 10.1073/pnas.0501985102 [Abstract] [Full Text] [Figures Only] [PDF]