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Table of Contents

April 26, 2005; 102 (17)  [Index By Author]  [Cover Photo]  [Masthead (PDF)]

FROM THE COVER

Vesicle recycling after endocytosis

Microcompartmentation in synthetic cells

Activation of transcriptional corepressors

Evolutionary dynamics of olfactory receptors

Gene expression and melanoma progression

IN THIS ISSUE

COMMENTARIES

PNAS CLASSIC PAPERS

PHYSICAL SCIENCES
    Chemistry
    Mathematics

SOCIAL SCIENCES
    Anthropology

BIOLOGICAL SCIENCES
    Applied Biological Sciences
    Biochemistry
    Biophysics
    Cell Biology
    Ecology
    Evolution
    Genetics

    Immunology
    Medical Sciences
    Microbiology
    Neuroscience
    Pharmacology
    Physiology
    Plant Biology

CORRECTIONS

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IN THIS ISSUE

In This Issue
PNAS 2005 102: 5899-5900. [Full Text] [Figures Only] [PDF]  

COMMENTARIES

Gary J. Pielak
A model of intracellular organization
PNAS 2005 102: 5901-5902; published online before print April 19 2005, 10.1073/pnas.0501812102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 5920

Duane P. Grandgenett
Symmetrical recognition of cellular DNA target sequences during retroviral integration
PNAS 2005 102: 5903-5904; published online before print April 19 2005, 10.1073/pnas.0502045102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 6103

PNAS CLASSIC PAPERS

Richard J. Roberts
Perspective: How restriction enzymes became the workhorses of molecular biology
PNAS 2005 102: 5905-5908; published online before print April 19 2005, 10.1073/pnas.0500923102 [Abstract] [Full Text] [Figures Only] [PDF]  

Christen Brownlee
Classics: Danna and Nathans: Restriction enzymes and the boon to modern molecular biology
PNAS 2005 102: 5909; published online before print April 19 2005, 10.1073/pnas.0502760102 [Extract] [Full Text] [PDF]  

PHYSICAL SCIENCES

Chemistry

M. Scott Long, Clinton D. Jones, Marcus R. Helfrich, Lauren K. Mangeney-Slavin, and Christine D. Keating
From The Cover: Dynamic microcompartmentation in synthetic cells
PNAS 2005 102: 5920-5925; published online before print March 23 2005, 10.1073/pnas.0409333102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  
See Commentary on page 5901

Tae Seok Seo, Xiaopeng Bai, Dae Hyun Kim, Qinglin Meng, Shundi Shi, Hameer Ruparel, Zengmin Li, Nicholas J. Turro, and Jingyue Ju
Four-color DNA sequencing by synthesis on a chip using photocleavable fluorescent nucleotides
PNAS 2005 102: 5926-5931; published online before print April 13 2005, 10.1073/pnas.0501965102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Hameer Ruparel, Lanrong Bi, Zengmin Li, Xiaopeng Bai, Dae Hyun Kim, Nicholas J. Turro, and Jingyue Ju
Design and synthesis of a 3'-O-allyl photocleavable fluorescent nucleotide as a reversible terminator for DNA sequencing by synthesis
PNAS 2005 102: 5932-5937; published online before print April 13 2005, 10.1073/pnas.0501962102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Nampally Sreenivasachary and Jean-Marie Lehn
Gelation-driven component selection in the generation of constitutional dynamic hydrogels based on guanine-quartet formation
PNAS 2005 102: 5938-5943; published online before print April 19 2005, 10.1073/pnas.0501663102 [Abstract] [Full Text] [Figures Only] [PDF]  

Robert M. McKinlay, Gareth W. V. Cave, and Jerry L. Atwood
Supramolecular blueprint approach to metal-coordinated capsules
PNAS 2005 102: 5944-5948; published online before print April 14 2005, 10.1073/pnas.0408113102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Mathematics

Diego Córdoba, Marco A. Fontelos, Ana M. Mancho, and Jose L. Rodrigo
Evidence of singularities for a family of contour dynamics equations
PNAS 2005 102: 5949-5952; published online before print April 18 2005, 10.1073/pnas.0501977102 [Abstract] [Full Text] [Figures Only] [PDF]  

SOCIAL SCIENCES

Anthropology

Todd Surovell, Nicole Waguespack, and P. Jeffrey Brantingham
Global archaeological evidence for proboscidean overkill
PNAS 2005 102: 6231-6236; published online before print April 13 2005, 10.1073/pnas.0501947102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

BIOLOGICAL SCIENCES

Applied Biological Sciences

Benjamin G. Keselowsky, David M. Collard, and Andrés J. García
Integrin binding specificity regulates biomaterial surface chemistry effects on cell differentiation
PNAS 2005 102: 5953-5957; published online before print April 12 2005, 10.1073/pnas.0407356102 [Abstract] [Full Text] [Figures Only] [PDF]  

Biochemistry

Jean Guillerez, Pascal J. Lopez, Florence Proux, Hélène Launay, and Marc Dreyfus
A mutation in T7 RNA polymerase that facilitates promoter clearance
PNAS 2005 102: 5958-5963; published online before print April 14 2005, 10.1073/pnas.0407141102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Rose A. Gubitosi-Klug, David J. Mancuso, and Richard W. Gross
The human Kv1.1 channel is palmitoylated, modulating voltage sensing: Identification of a palmitoylation consensus sequence
PNAS 2005 102: 5964-5968; published online before print April 18 2005, 10.1073/pnas.0501999102 [Abstract] [Full Text] [Figures Only] [PDF]  

Xinchun Shen, C. Alexander Valencia, Jack W. Szostak, Biao Dong, and Rihe Liu
Scanning the human proteome for calmodulin-binding proteins
PNAS 2005 102: 5969-5974; published online before print April 19 2005, 10.1073/pnas.0407928102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Florence Mousson, Aurélie Lautrette, Jean-Yves Thuret, Morgane Agez, Régis Courbeyrette, Béatrice Amigues, Emmanuelle Becker, Jean-Michel Neumann, Raphaël Guerois, Carl Mann, and Françoise Ochsenbein
Structural basis for the interaction of Asf1 with histone H3 and its functional implications
PNAS 2005 102: 5975-5980; published online before print April 19 2005, 10.1073/pnas.0500149102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Mindy I. Davis, Melanie J. Bennett, Leonard M. Thomas, and Pamela J. Bjorkman
Crystal structure of prostate-specific membrane antigen, a tumor marker and peptidase
PNAS 2005 102: 5981-5986; published online before print April 18 2005, 10.1073/pnas.0502101102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Anne-Laure Bulteau, Kathleen C. Lundberg, Masao Ikeda-Saito, Grazia Isaya, and Luke I. Szweda
Reversible redox-dependent modulation of mitochondrial aconitase and proteolytic activity during in vivo cardiac ischemia/reperfusion
PNAS 2005 102: 5987-5991; published online before print April 19 2005, 10.1073/pnas.0501519102 [Abstract] [Full Text] [Figures Only] [PDF]  

Arvind Ramanathan, Connie Wang, and Stuart L. Schreiber
Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements
PNAS 2005 102: 5992-5997; published online before print April 19 2005, 10.1073/pnas.0502267102 [Abstract] [Full Text] [Figures Only] [PDF]  

Sangkil Nam, Ralf Buettner, James Turkson, Donghwa Kim, Jin Q. Cheng, Stephan Muehlbeyer, Frankie Hippe, Sandra Vatter, Karl-Heinz Merz, Gerhard Eisenbrand, and Richard Jove
Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells
PNAS 2005 102: 5998-6003; published online before print April 18 2005, 10.1073/pnas.0409467102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Biophysics

Tae Seok Seo, Xiaopeng Bai, Dae Hyun Kim, Qinglin Meng, Shundi Shi, Hameer Ruparel, Zengmin Li, Nicholas J. Turro, and Jingyue Ju
Four-color DNA sequencing by synthesis on a chip using photocleavable fluorescent nucleotides
PNAS 2005 102: 5926-5931; published online before print April 13 2005, 10.1073/pnas.0501965102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Hameer Ruparel, Lanrong Bi, Zengmin Li, Xiaopeng Bai, Dae Hyun Kim, Nicholas J. Turro, and Jingyue Ju
Design and synthesis of a 3'-O-allyl photocleavable fluorescent nucleotide as a reversible terminator for DNA sequencing by synthesis
PNAS 2005 102: 5932-5937; published online before print April 13 2005, 10.1073/pnas.0501962102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

M. G. Sacerdote and J. W. Szostak
Semipermeable lipid bilayers exhibit diastereoselectivity favoring ribose
PNAS 2005 102: 6004-6008; published online before print April 14 2005, 10.1073/pnas.0408440102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Anna Codina, James D. Love, Yun Li, Mitchell A. Lazar, David Neuhaus, and John W. R. Schwabe
From The Cover: Structural insights into the interaction and activation of histone deacetylase 3 by nuclear receptor corepressors
PNAS 2005 102: 6009-6014; published online before print April 18 2005, 10.1073/pnas.0500299102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jose M. Borreguero, Brigita Urbanc, Noel D. Lazo, Sergey V. Buldyrev, David B. Teplow, and H. Eugene Stanley
Folding events in the 21-30 region of amyloid {beta}-protein (A{beta}) studied in silico
PNAS 2005 102: 6015-6020; published online before print April 18 2005, 10.1073/pnas.0502006102 [Abstract] [Full Text] [Figures Only] [PDF]  

Cell Biology

Sandra Grau, Alfonso Baldi, Rossana Bussani, Xiaodan Tian, Raluca Stefanescu, Michael Przybylski, Peter Richards, Simon A. Jones, Viji Shridhar, Tim Clausen, and Michael Ehrmann
Implications of the serine protease HtrA1 in amyloid precursor protein processing
PNAS 2005 102: 6021-6026. [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ming Yang, Wendy W. Zhong, Neelam Srivastava, Anthony Slavin, Jianxin Yang, Timothy Hoey, and Songzhu An
G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the {beta}-catenin pathway
PNAS 2005 102: 6027-6032; published online before print April 18 2005, 10.1073/pnas.0501535102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ecology

B. R. Scanlon, D. G. Levitt, R. C. Reedy, K. E. Keese, and M. J. Sully
Ecological controls on water-cycle response to climate variability in deserts
PNAS 2005 102: 6033-6038; published online before print April 18 2005, 10.1073/pnas.0408571102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Evolution

Yoshihito Niimura and Masatoshi Nei
From The Cover: Evolutionary dynamics of olfactory receptor genes in fishes and tetrapods
PNAS 2005 102: 6039-6044; published online before print April 11 2005, 10.1073/pnas.0501922102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Donna Petfield, Stephen F. Chenoweth, Howard D. Rundle, and Mark W. Blows
Genetic variance in female condition predicts indirect genetic variance in male sexual display traits
PNAS 2005 102: 6045-6050; published online before print April 19 2005, 10.1073/pnas.0409378102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Genetics

Bijal Trivedi
Inaugural Article by a Recently Elected Academy Member:
Inaugural Article: Biography of Kathryn V. Anderson
PNAS 2005 102: 5910-5912; published online before print April 19 2005, 10.1073/pnas.0501900102 [Extract] [Full Text] [Figures Only] [PDF]  

María J. García-García, Jonathan T. Eggenschwiler, Tamara Caspary, Heather L. Alcorn, Michael R. Wyler, Danwei Huangfu, Andrew S. Rakeman, Jeffrey D. Lee, Evan H. Feinberg, John R. Timmer, and Kathryn V. Anderson
Inaugural Article by a Recently Elected Academy Member:
Inaugural Article: Analysis of mouse embryonic patterning and morphogenesis by forward genetics
PNAS 2005 102: 5913-5919; published online before print March 8 2005, 10.1073/pnas.0501071102 [Abstract] [Full Text] [Figures Only] [PDF]  

Anne Goriely, Gilean A. T. McVean, Ans M. M. van Pelt, Anthony W. O'Rourke, Steven A. Wall, Dirk G. de Rooij, and Andrew O. M. Wilkie
Gain-of-function amino acid substitutions drive positive selection of FGFR2 mutations in human spermatogonia
PNAS 2005 102: 6051-6056; published online before print April 19 2005, 10.1073/pnas.0500267102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Akitsugu Sato, Kazuto Nakada, Miho Akimoto, Kaori Ishikawa, Tomoko Ono, Hiroshi Shitara, Hiromichi Yonekawa, and Jun-Ichi Hayashi
Rare creation of recombinant mtDNA haplotypes in mammalian tissues
PNAS 2005 102: 6057-6062; published online before print April 13 2005, 10.1073/pnas.0408666102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Atsuko Shimada, Akihiro Shima, Kumie Nojima, Yo Seino, and Richard B. Setlow
Germ cell mutagenesis in medaka fish after exposures to high-energy cosmic ray nuclei: A human model
PNAS 2005 102: 6063-6067; published online before print April 13 2005, 10.1073/pnas.0500895102 [Abstract] [Full Text] [Figures Only] [PDF]  

Immunology

David M. Langenau, Hui Feng, Stephane Berghmans, John P. Kanki, Jeffery L. Kutok, and A. Thomas Look
Cre/lox-regulated transgenic zebrafish model with conditional myc-induced T cell acute lymphoblastic leukemia
PNAS 2005 102: 6068-6073; published online before print April 12 2005, 10.1073/pnas.0408708102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Dana R. Marshall, Elvia Olivas, Samita Andreansky, Nicole L. La Gruta, Geoff A. Neale, Astrid Gutierrez, David G. Wichlan, Suzette Wingo, Cheng Cheng, Peter C. Doherty, and Stephen J. Turner
Effector CD8+ T cells recovered from an influenza pneumonia differentiate to a state of focused gene expression
PNAS 2005 102: 6074-6079; published online before print April 14 2005, 10.1073/pnas.0501960102 [Abstract] [Full Text] [Figures Only] [PDF]  

Medical Sciences

Lingfei Xu, Timothy C. Nichols, Rita Sarkar, Stephanie McCorquodale, Dwight A. Bellinger, and Katherine P. Ponder
Absence of a desmopressin response after therapeutic expression of factor VIII in hemophilia A dogs with liver-directed neonatal gene therapy
PNAS 2005 102: 6080-6085; published online before print April 18 2005, 10.1073/pnas.0409249102 [Abstract] [Full Text] [Figures Only] [PDF]  

Aimin Xu, Michael C. Lam, Kok Weng Chan, Yu Wang, Jialiang Zhang, Ruby L. C. Hoo, Jian Yu Xu, Baoying Chen, Wing-Sun Chow, Annette W. K. Tso, and Karen S. L. Lam
Angiopoietin-like protein 4 decreases blood glucose and improves glucose tolerance but induces hyperlipidemia and hepatic steatosis in mice
PNAS 2005 102: 6086-6091; published online before print April 18 2005, 10.1073/pnas.0408452102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Christopher Haqq, Mehdi Nosrati, Daniel Sudilovsky, Julia Crothers, Daniel Khodabakhsh, Brian L. Pulliam, Scot Federman, James R. Miller, III, Robert E. Allen, Mark I. Singer, Stanley P. L. Leong, Britt-Marie Ljung, Richard W. Sagebiel, and Mohammed Kashani-Sabet
From The Cover: The gene expression signatures of melanoma progression
PNAS 2005 102: 6092-6097; published online before print April 15 2005, 10.1073/pnas.0501564102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Katarzyna Lundmark, Gunilla T. Westermark, Arne Olsén, and Per Westermark
Protein fibrils in nature can enhance amyloid protein A amyloidosis in mice: Cross-seeding as a disease mechanism
PNAS 2005 102: 6098-6102; published online before print April 13 2005, 10.1073/pnas.0501814102 [Abstract] [Full Text] [Figures Only] [PDF]  

Microbiology

Alexander G. Holman and John M. Coffin
Symmetrical base preferences surrounding HIV-1, avian sarcoma/leukosis virus, and murine leukemia virus integration sites
PNAS 2005 102: 6103-6107; published online before print March 31 2005, 10.1073/pnas.0501646102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  
See Commentary on page 5903

F. Douglas Ivey and Charles S. Hoffman
Direct activation of fission yeast adenylate cyclase by the Gpa2 G{alpha} of the glucose signaling pathway
PNAS 2005 102: 6108-6113; published online before print April 14 2005, 10.1073/pnas.0502270102 [Abstract] [Full Text] [Figures Only] [PDF]  

Donald A. Drew, Mary J. Osborn, and Lawrence I. Rothfield
A polymerization-depolymerization model that accurately generates the self-sustained oscillatory system involved in bacterial division site placement
PNAS 2005 102: 6114-6118; published online before print April 19 2005, 10.1073/pnas.0502037102 [Abstract] [Full Text] [Figures Only] [PDF]  

Shah M. Faruque, M. Johirul Islam, Qazi Shafi Ahmad, A. S. G. Faruque, David A. Sack, G. Balakrish Nair, and John J. Mekalanos
Self-limiting nature of seasonal cholera epidemics: Role of host-mediated amplification of phage
PNAS 2005 102: 6119-6124; published online before print April 13 2005, 10.1073/pnas.0502069102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Neuroscience

Longnian Lin, Remus Osan, Shy Shoham, Wenjun Jin, Wenqi Zuo, and Joe Z. Tsien
Identification of network-level coding units for real-time representation of episodic experiences in the hippocampus
PNAS 2005 102: 6125-6130; published online before print April 15 2005, 10.1073/pnas.0408233102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Zhiying Li, Juan Burrone, William J. Tyler, Kenichi N. Hartman, Dinu F. Albeanu, and Venkatesh N. Murthy
From The Cover: Synaptic vesicle recycling studied in transgenic mice expressing synaptopHluorin
PNAS 2005 102: 6131-6136; published online before print April 18 2005, 10.1073/pnas.0501145102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  
See Commentary on page 7407

Christine I. Nam and Lu Chen
Postsynaptic assembly induced by neurexin-neuroligin interaction and neurotransmitter
PNAS 2005 102: 6137-6142; published online before print April 18 2005, 10.1073/pnas.0502038102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

M. A. Kingsbury, B. Friedman, M. J. McConnell, S. K. Rehen, A. H. Yang, D. Kaushal, and J. Chun
Aneuploid neurons are functionally active and integrated into brain circuitry
PNAS 2005 102: 6143-6147; published online before print April 18 2005, 10.1073/pnas.0408171102 [Abstract] [Full Text] [Figures Only] [PDF]  

Siegfried Alberti, Sven M. Krause, Oliver Kretz, Ulrike Philippar, Thomas Lemberger, Emilio Casanova, Franziska F. Wiebel, Heinz Schwarz, Michael Frotscher, Günther Schütz, and Alfred Nordheim
Neuronal migration in the murine rostral migratory stream requires serum response factor
PNAS 2005 102: 6148-6153; published online before print April 18 2005, 10.1073/pnas.0501191102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Einav Cohen-Kfir, William Lee, Sepehr Eskandari, and Nathan Nelson
Zinc inhibition of {gamma}-aminobutyric acid transporter 4 (GAT4) reveals a link between excitatory and inhibitory neurotransmission
PNAS 2005 102: 6154-6159; published online before print April 13 2005, 10.1073/pnas.0501431102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE  

Daniel Kerschensteiner, Florentina Soto, and Martin Stocker
Fluorescence measurements reveal stoichiometry of K+ channels formed by modulatory and delayed rectifier {alpha}-subunits
PNAS 2005 102: 6160-6165; published online before print April 12 2005, 10.1073/pnas.0500468102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

David A. Richards, José Maria Mateos, Sylvain Hugel, Vincenzo de Paola, Pico Caroni, Beat H. Gähwiler, and R. Anne McKinney
Glutamate induces the rapid formation of spine head protrusions in hippocampal slice cultures
PNAS 2005 102: 6166-6171; published online before print April 14 2005, 10.1073/pnas.0501881102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Alexander Borst, Virginia L. Flanagin, and Haim Sompolinsky
Adaptation without parameter change: Dynamic gain control in motion detection
PNAS 2005 102: 6172-6176; published online before print April 15 2005, 10.1073/pnas.0500491102 [Abstract] [Full Text] [Figures Only] [PDF]  

Samuel G. Jacobson, Tomas S. Aleman, Artur V. Cideciyan, Alexander Sumaroka, Sharon B. Schwartz, Elizabeth A. M. Windsor, Elias I. Traboulsi, Elise Heon, Steven J. Pittler, Ann H. Milam, Albert M. Maguire, Krzysztof Palczewski, Edwin M. Stone, and Jean Bennett
Identifying photoreceptors in blind eyes caused by RPE65 mutations: Prerequisite for human gene therapy success
PNAS 2005 102: 6177-6182; published online before print April 18 2005, 10.1073/pnas.0500646102 [Abstract] [Full Text] [Figures Only] [PDF]  

Damián Refojo, Carlos Echenique, Marianne B. Müller, Johannes M. H. M. Reul, Jan M. Deussing, Wolfgang Wurst, Inge Sillaber, Marcelo Paez-Pereda, Florian Holsboer, and Eduardo Arzt
Corticotropin-releasing hormone activates ERK1/2 MAPK in specific brain areas
PNAS 2005 102: 6183-6188; published online before print April 15 2005, 10.1073/pnas.0502070102 [Abstract] [Full Text] [Figures Only] [PDF]  

Jeffrey W. Dalley, Kristjan Lääne, David E. H. Theobald, Hannah C. Armstrong, Philip R. Corlett, Yogita Chudasama, and Trevor W. Robbins
Time-limited modulation of appetitive Pavlovian memory by D1 and NMDA receptors in the nucleus accumbens
PNAS 2005 102: 6189-6194; published online before print April 15 2005, 10.1073/pnas.0502080102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure] OPEN ACCESS ARTICLE  

Pharmacology

Daniel K. Nomura, Donmienne Leung, Kyle P. Chiang, Gary B. Quistad, Benjamin F. Cravatt, and John E. Casida
A brain detoxifying enzyme for organophosphorus nerve poisons
PNAS 2005 102: 6195-6200; published online before print April 19 2005, 10.1073/pnas.0501915102 [Abstract] [Full Text] [Figures Only] [PDF]  

Casey E. Bohl, Wenqing Gao, Duane D. Miller, Charles E. Bell, and James T. Dalton
Structural basis for antagonism and resistance of bicalutamide in prostate cancer
PNAS 2005 102: 6201-6206; published online before print April 15 2005, 10.1073/pnas.0500381102 [Abstract] [Full Text] [Figures Only] [PDF]  

Physiology

Julie R. Jones, Cordelia Barrick, Kyoung-Ah Kim, Jill Lindner, Bertrand Blondeau, Yuka Fujimoto, Masakazu Shiota, Robert A. Kesterson, Barbara B. Kahn, and Mark A. Magnuson
Deletion of PPAR{gamma} in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance
PNAS 2005 102: 6207-6212; published online before print April 15 2005, 10.1073/pnas.0306743102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE  

Claudia E. Mohn, Javier Fernandez-Solari, Andrea De Laurentiis, Juan Pablo Prestifilippo, Carolina de la Cal, Richard Funk, Stefan R. Bornstein, Samuel M. McCann, and Valeria Rettori
The rapid release of corticosterone from the adrenal induced by ACTH is mediated by nitric oxide acting by prostaglandin E2
PNAS 2005 102: 6213-6218; published online before print April 18 2005, 10.1073/pnas.0502136102 [Abstract] [Full Text] [Figures Only] [PDF]  

Plant Biology

Livia Stavolone, Maria Elena Villani, Denis Leclerc, and Thomas Hohn
A coiled-coil interaction mediates cauliflower mosaic virus cell-to-cell movement
PNAS 2005 102: 6219-6224; published online before print April 18 2005, 10.1073/pnas.0407731102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Alexander Levitan, Tova Trebitsh, Vladimir Kiss, Yaron Pereg, Inbal Dangoor, and Avihai Danon
Dual targeting of the protein disulfide isomerase RB60 to the chloroplast and the endoplasmic reticulum
PNAS 2005 102: 6225-6230; published online before print April 18 2005, 10.1073/pnas.0500676102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

CORRECTIONS

Correction for Hung et al., HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol, PNAS 2005 102:4134-4139 [Extract] [Full Text] [PDF]  

Correction for Marino, Inaugural Article: Biography of Cornelia I. Bargmann, PNAS 2005 102:3181-3183 [Extract] [Full Text] [PDF]  

Correction for Holman et al., Symmetrical base preferences surrounding HIV-1, avian sarcoma/leukosis virus, and murine leukemia virus integration sites, PNAS 2005 102:6103-6107 [Extract] [Full Text] [Figures Only] [PDF]  

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