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Table of Contents

June 14, 2005; 102 (24)  [Index By Author]  [Cover Photo]  [Masthead (PDF)]

FROM THE COVER

Nicotinic receptors and insecticide resistance

Ubiquitin ligase and neurodegenerative disease

Signals required for blastocyst implantation

Ancient origin of vertebrate immune systems

Selective advantage of microbial fratricide

IN THIS ISSUE

COMMENTARIES

PERSPECTIVES

PHYSICAL SCIENCES
    Chemistry

SOCIAL SCIENCES
    Psychology

BIOLOGICAL SCIENCES
    Agricultural Sciences
    Anthropology
    Applied Biological Sciences
    Biochemistry
    Biophysics
    Cell Biology
    Developmental Biology
    Evolution
    Genetics

    Immunology
    Medical Sciences
    Microbiology
    Neuroscience
    Pharmacology
    Plant Biology

CORRECTIONS

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IN THIS ISSUE

This Week in PNAS
PNAS 2005 102: 8393-8394. [Full Text] [Figures Only] [PDF]  

COMMENTARIES

Harry W. Greene
Historical influences on community ecology
PNAS 2005 102: 8395-8396; published online before print June 6 2005, 10.1073/pnas.0503367102 [Extract] [Full Text] [PDF]  
See companion article on page 7877 in issue 22 of volume 102

Daniel D. Carson
Uterine sensing of the embryo
PNAS 2005 102: 8397-8398; published online before print June 6 2005, 10.1073/pnas.0503417102 [Extract] [Full Text] [PDF]  
See companion article on page 8579

Steven A. Porcelli
Bird genes give new insights into the origins of lipid antigen presentation
PNAS 2005 102: 8399-8400; published online before print June 6 2005, 10.1073/pnas.0503313102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 8668
See companion article on page 8674

M. S. Gilmore and W. Haas
The selective advantage of microbial fratricide
PNAS 2005 102: 8401-8402; published online before print June 6 2005, 10.1073/pnas.0503828102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 8710

PERSPECTIVES

Frank Wilczek
Nobel Lecture: Asymptotic freedom: From paradox to paradigm
PNAS 2005 102: 8403-8413; published online before print June 8 2005, 10.1073/pnas.0501642102 [Extract] [Full Text] [Figures Only] [PDF]  

PHYSICAL SCIENCES

Chemistry

Hidenori Yokoi, Takatoshi Kinoshita, and Shuguang Zhang
Dynamic reassembly of peptide RADA16 nanofiber scaffold
PNAS 2005 102: 8414-8419; published online before print June 6 2005, 10.1073/pnas.0407843102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

SOCIAL SCIENCES

Psychology

Henrik Olsson and Leo Poom
Visual memory needs categories
PNAS 2005 102: 8776-8780; published online before print June 3 2005, 10.1073/pnas.0500810102 [Abstract] [Full Text] [Figures Only] [PDF]  

Li Hai Tan, John A. Spinks, Guinevere F. Eden, Charles A. Perfetti, and Wai Ting Siok
Reading depends on writing, in Chinese
PNAS 2005 102: 8781-8785; published online before print June 6 2005, 10.1073/pnas.0503523102 [Abstract] [Full Text] [Figures Only] [PDF]  

BIOLOGICAL SCIENCES

Agricultural Sciences

Zewen Liu, Martin S. Williamson, Stuart J. Lansdell, Ian Denholm, Zhaojun Han, and Neil S. Millar
From The Cover: A nicotinic acetylcholine receptor mutation conferring target-site resistance to imidacloprid in Nilaparvata lugens (brown planthopper)
PNAS 2005 102: 8420-8425; published online before print June 3 2005, 10.1073/pnas.0502901102 [Abstract] [Full Text] [Figures Only] [PDF]  

Jian-Zhou Zhao, Jun Cao, Hilda L. Collins, Sarah L. Bates, Richard T. Roush, Elizabeth D. Earle, and Anthony M. Shelton
Concurrent use of transgenic plants expressing a single and two Bacillus thuringiensis genes speeds insect adaptation to pyramided plants
PNAS 2005 102: 8426-8430; published online before print June 6 2005, 10.1073/pnas.0409324102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE  

Cecilia Anderung, Abigail Bouwman, Per Persson, José Miguel Carretero, Ana Isabel Ortega, Rengert Elburg, Colin Smith, Juan Luis Arsuaga, Hans Ellegren, and Anders Götherström
Prehistoric contacts over the Straits of Gibraltar indicated by genetic analysis of Iberian Bronze Age cattle
PNAS 2005 102: 8431-8435; published online before print June 7 2005, 10.1073/pnas.0503396102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Anthropology

Laurent Marivaux, Pierre-Olivier Antoine, Syed Rafiqul Hassan Baqri, Mouloud Benammi, Yaowalak Chaimanee, Jean-Yves Crochet, Dario de Franceschi, Nayyer Iqbal, Jean-Jacques Jaeger, Grégoire Métais, Ghazala Roohi, and Jean-Loup Welcomme
Anthropoid primates from the Oligocene of Pakistan (Bugti Hills): Data on early anthropoid evolution and biogeography
PNAS 2005 102: 8436-8441; published online before print June 3 2005, 10.1073/pnas.0503469102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Applied Biological Sciences

Katsueki Ogiwara, Naoharu Takano, Masakazu Shinohara, Masahiro Murakami, and Takayuki Takahashi
Gelatinase A and membrane-type matrix metalloproteinases 1 and 2 are responsible for follicle rupture during ovulation in the medaka
PNAS 2005 102: 8442-8447; published online before print June 7 2005, 10.1073/pnas.0502423102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Biochemistry

John Verbsky, Kory Lavine, and Philip W. Majerus
Disruption of the mouse inositol 1,3,4,5,6-pentakisphosphate 2-kinase gene, associated lethality, and tissue distribution of 2-kinase expression
PNAS 2005 102: 8448-8453; published online before print June 6 2005, 10.1073/pnas.0503656102 [Abstract] [Full Text] [Figures Only] [PDF]  

Joshua P. Frederick, Deidre Mattiske, Jessica A. Wofford, Louis C. Megosh, Li Yin Drake, Shean-Tai Chiou, Brigid L. M. Hogan, and John D. York
An essential role for an inositol polyphosphate multikinase, Ipk2, in mouse embryogenesis and second messenger production
PNAS 2005 102: 8454-8459; published online before print June 6 2005, 10.1073/pnas.0503706102 [Abstract] [Full Text] [Figures Only] [PDF]  

Kostas Hatzixanthis, Thomas A. Clarke, Arthur Oubrie, David J. Richardson, Raymond J. Turner, and Frank Sargent
Signal peptide–chaperone interactions on the twin-arginine protein transport pathway
PNAS 2005 102: 8460-8465; published online before print June 7 2005, 10.1073/pnas.0500737102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE  

Arvind Rajpal, Nurten Beyaz, Lauric Haber, Guido Cappuccilli, Helena Yee, Ramesh R. Bhatt, Toshihiko Takeuchi, Richard A. Lerner, and Roberto Crea
A general method for greatly improving the affinity of antibodies by using combinatorial libraries
PNAS 2005 102: 8466-8471; published online before print June 6 2005, 10.1073/pnas.0503543102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table] OPEN ACCESS ARTICLE  

Vikas B. Palhan, Shiming Chen, Guang-Hua Peng, Agneta Tjernberg, Armin M. Gamper, Yuxin Fan, Brian T. Chait, Albert R. La Spada, and Robert G. Roeder
Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration
PNAS 2005 102: 8472-8477; published online before print June 2 2005, 10.1073/pnas.0503505102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Stacey J. McMahon, Marilyn G. Pray-Grant, David Schieltz, John R. Yates, III, and Patrick A. Grant
Polyglutamine-expanded spinocerebellar ataxia-7 protein disrupts normal SAGA and SLIK histone acetyltransferase activity
PNAS 2005 102: 8478-8482; published online before print June 2 2005, 10.1073/pnas.0503493102 [Abstract] [Full Text] [Figures Only] [PDF]  

Maurizio Brunori, Alessandro Giuffrè, Karin Nienhaus, G. Ulrich Nienhaus, Francesca Maria Scandurra, and Beatrice Vallone
Neuroglobin, nitric oxide, and oxygen: Functional pathways and conformational changes
PNAS 2005 102: 8483-8488; published online before print June 2 2005, 10.1073/pnas.0408766102 [Abstract] [Full Text] [Figures Only] [PDF]  

Zhonggang Hou, Douglas A. Bernstein, Catherine A. Fox, and James L. Keck
Structural basis of the Sir1–origin recognition complex interaction in transcriptional silencing
PNAS 2005 102: 8489-8494; published online before print June 2 2005, 10.1073/pnas.0503525102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Chotima Boettcher, Monika Fellermeier, Christian Boettcher, Birgit Dräger, and Meinhart H. Zenk
How human neuroblastoma cells make morphine
PNAS 2005 102: 8495-8500; published online before print June 3 2005, 10.1073/pnas.0503244102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Matthew S. Gentry, Carolyn A. Worby, and Jack E. Dixon
From The Cover: Insights into Lafora disease: Malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin
PNAS 2005 102: 8501-8506; published online before print June 1 2005, 10.1073/pnas.0503285102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Filiz M. Aslan, Yong Yu, Scott C. Mohr, and Charles R. Cantor
Engineered single-chain dimeric streptavidins with an unexpected strong preference for biotin-4-fluorescein
PNAS 2005 102: 8507-8512; published online before print June 6 2005, 10.1073/pnas.0503112102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Qiang Yang, Xicheng Wang, Liwen Ye, Mark Mentrikoski, Elham Mohammadi, Young-Mog Kim, and Peter C. Maloney
Experimental tests of a homology model for OxlT, the oxalate transporter of Oxalobacter formigenes
PNAS 2005 102: 8513-8518; published online before print June 2 2005, 10.1073/pnas.0503533102 [Abstract] [Full Text] [Figures Only] [PDF]  

Hao-Chi Hsu, Bruce Stillman, and Rui-Ming Xu
Structural basis for origin recognition complex 1 protein–silence information regulator 1 protein interaction in epigenetic silencing
PNAS 2005 102: 8519-8524; published online before print June 3 2005, 10.1073/pnas.0502946102 [Abstract] [Full Text] [Figures Only] [PDF]  

Antonio Martínez-Ruiz, Laura Villanueva, Cecilia González de Orduña, Daniel López-Ferrer, María Ángeles Higueras, Carlos Tarín, Ignacio Rodríguez-Crespo, Jesús Vázquez, and Santiago Lamas
S-nitrosylation of Hsp90 promotes the inhibition of its ATPase and endothelial nitric oxide synthase regulatory activities
PNAS 2005 102: 8525-8530; published online before print June 3 2005, 10.1073/pnas.0407294102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Biophysics

Chien Peter Chen, Shoshana Posy, Avinoam Ben-Shaul, Lawrence Shapiro, and Barry H. Honig
Specificity of cell–cell adhesion by classical cadherins: Critical role for low-affinity dimerization through {beta}-strand swapping
PNAS 2005 102: 8531-8536; published online before print June 3 2005, 10.1073/pnas.0503319102 [Abstract] [Full Text] [Figures Only] [PDF]  

Vitold E. Galkin, Fumiko Esashi, Xiong Yu, Shixin Yang, Stephen C. West, and Edward H. Egelman
BRCA2 BRC motifs bind RAD51–DNA filaments
PNAS 2005 102: 8537-8542; published online before print June 3 2005, 10.1073/pnas.0407266102 [Abstract] [Full Text] [Figures Only] [PDF]  

Dimitrios Vavylonis, Qingbo Yang, and Ben O'Shaughnessy
Actin polymerization kinetics, cap structure, and fluctuations
PNAS 2005 102: 8543-8548; published online before print June 6 2005, 10.1073/pnas.0501435102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Cell Biology

Victor Soukoulis, Samyukta Reddy, Ryan D. Pooley, Yuanyi Feng, Christopher A. Walsh, and David M. Bader
Cytoplasmic LEK1 is a regulator of microtubule function through its interaction with the LIS1 pathway
PNAS 2005 102: 8549-8554; published online before print June 6 2005, 10.1073/pnas.0502303102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Noriaki Shimizu, Rika Ouchida, Noritada Yoshikawa, Tetsuya Hisada, Hajime Watanabe, Kensaku Okamoto, Masatoshi Kusuhara, Hiroshi Handa, Chikao Morimoto, and Hirotoshi Tanaka
HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor b
PNAS 2005 102: 8555-8560; published online before print June 7 2005, 10.1073/pnas.0409863102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Alexander C. Zambon, Lingzhi Zhang, Simon Minovitsky, Joan R. Kanter, Shyam Prabhakar, Nathan Salomonis, Karen Vranizan, Inna Dubchak, Bruce R. Conklin, and Paul A. Insel
Gene expression patterns define key transcriptional events in cell-cycle regulation by cAMP and protein kinase A
PNAS 2005 102: 8561-8566; published online before print June 6 2005, 10.1073/pnas.0503363102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Teru Hideshima, James E. Bradner, Jason Wong, Dharminder Chauhan, Paul Richardson, Stuart L. Schreiber, and Kenneth C. Anderson
Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma
PNAS 2005 102: 8567-8572; published online before print June 3 2005, 10.1073/pnas.0503221102 [Abstract] [Full Text] [Figures Only] [PDF]  

Cory M. Johannessen, Elizabeth E. Reczek, Marianne F. James, Hilde Brems, Eric Legius, and Karen Cichowski
The NF1 tumor suppressor critically regulates TSC2 and mTOR
PNAS 2005 102: 8573-8578; published online before print June 3 2005, 10.1073/pnas.0503224102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE  

Developmental Biology

Othman A. Mohamed, Maud Jonnaert, Cassandre Labelle-Dumais, Kazuki Kuroda, Hugh J. Clarke, and Daniel Dufort
From The Cover: Uterine Wnt/{beta}-catenin signaling is required for implantation
PNAS 2005 102: 8579-8584; published online before print June 1 2005, 10.1073/pnas.0500612102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  
See Commentary on page 8397

Rob D. Catalano, Martin H. Johnson, Elizabeth A. Campbell, D. Stephen Charnock-Jones, Stephen K. Smith, and Andrew M. Sharkey
Inhibition of Stat3 activation in the endometrium prevents implantation: A nonsteroidal approach to contraception
PNAS 2005 102: 8585-8590; published online before print June 3 2005, 10.1073/pnas.0502343102 [Abstract] [Full Text] [Figures Only] [PDF]  

Evolution

James P. Balhoff and Gregory A. Wray
Evolutionary analysis of the well characterized endo16 promoter reveals substantial variation within functional sites
PNAS 2005 102: 8591-8596; published online before print June 3 2005, 10.1073/pnas.0409638102 [Abstract] [Full Text] [Figures Only] [PDF]  

Daniel Riester, Frank Wirsching, Gabriela Salinas, Martina Keller, Michael Gebinoga, Stefan Kamphausen, Christian Merkwirth, Ruediger Goetz, Martin Wiesenfeldt, Jörg Stürzebecher, Wolfram Bode, Rainer Friedrich, Marcel Thürk, and Andreas Schwienhorst
Thrombin inhibitors identified by computer-assisted multiparameter design
PNAS 2005 102: 8597-8602; published online before print June 3 2005, 10.1073/pnas.0501983102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Genetics

Matthew G. Guenther, Richard G. Jenner, Brett Chevalier, Tatsuya Nakamura, Carlo M. Croce, Eli Canaani, and Richard A. Young
Global and Hox-specific roles for the MLL1 methyltransferase
PNAS 2005 102: 8603-8608; published online before print June 7 2005, 10.1073/pnas.0503072102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Kenneth E. Pierce, J. Aquiles Sanchez, John E. Rice, and Lawrence J. Wangh
Linear-After-The-Exponential (LATE)-PCR: Primer design criteria for high yields of specific single-stranded DNA and improved real-time detection
PNAS 2005 102: 8609-8614; published online before print June 3 2005, 10.1073/pnas.0501946102 [Abstract] [Full Text] [Figures Only] [PDF]  

Hsiao-Man Ivy Yu, Bo Liu, Shang-Yi Chiu, Frank Costantini, and Wei Hsu
Development of a unique system for spatiotemporal and lineage-specific gene expression in mice
PNAS 2005 102: 8615-8620; published online before print June 7 2005, 10.1073/pnas.0500124102 [Abstract] [Full Text] [Figures Only] [PDF]  

T. Mijalski, A. Harder, T. Halder, M. Kersten, M. Horsch, T. M. Strom, H. V. Liebscher, F. Lottspeich, M. Hrabe de Angelis, and J. Beckers
Identification of coexpressed gene clusters in a comparative analysis of transcriptome and proteome in mouse tissues
PNAS 2005 102: 8621-8626; published online before print June 6 2005, 10.1073/pnas.0407672102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables] OPEN ACCESS ARTICLE  

Joseph H. Callicott, Richard E. Straub, Lukas Pezawas, Michael F. Egan, Venkata S. Mattay, Ahmad R. Hariri, Beth A. Verchinski, Andreas Meyer-Lindenberg, Rishi Balkissoon, Bhaskar Kolachana, Terry E. Goldberg, and Daniel R. Weinberger
Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia
PNAS 2005 102: 8627-8632; published online before print June 6 2005, 10.1073/pnas.0500515102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Staffan Persson, Hairong Wei, Jennifer Milne, Grier P. Page, and Christopher R. Somerville
Identification of genes required for cellulose synthesis by regression analysis of public microarray data sets
PNAS 2005 102: 8633-8638; published online before print June 2 2005, 10.1073/pnas.0503392102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Joshua D. Hawk, Lela Stefanovic, Jayne C. Boyer, Thomas D. Petes, and Rosann A. Farber
Variation in efficiency of DNA mismatch repair at different sites in the yeast genome
PNAS 2005 102: 8639-8643; published online before print June 2 2005, 10.1073/pnas.0503415102 [Abstract] [Full Text] [Figures Only] [PDF]  

Jennifer D. Cook, Barbara J. Davis, Sheng-Li Cai, J. Carl Barrett, Claudio J. Conti, and Cheryl Lyn Walker
Interaction between genetic susceptibility and early-life environmental exposure determines tumor-suppressor-gene penetrance
PNAS 2005 102: 8644-8649; published online before print June 3 2005, 10.1073/pnas.0503218102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Yachuan Yu, Yumin Teng, Hairong Liu, Simon H. Reed, and Raymond Waters
UV irradiation stimulates histone acetylation and chromatin remodeling at a repressed yeast locus
PNAS 2005 102: 8650-8655; published online before print June 6 2005, 10.1073/pnas.0501458102 [Abstract] [Full Text] [Figures Only] [PDF]  

Immunology

Stella A. Martomo, William W. Yang, Robert P. Wersto, Tsuyoshi Ohkumo, Yuji Kondo, Masayuki Yokoi, Chikahide Masutani, Fumio Hanaoka, and Patricia J. Gearhart
Different mutation signatures in DNA polymerase {eta}- and MSH6-deficient mice suggest separate roles in antibody diversification
PNAS 2005 102: 8656-8661; published online before print June 6 2005, 10.1073/pnas.0501852102 [Abstract] [Full Text] [Figures Only] [PDF]  

Sigrid P. Dubois, Thomas A. Waldmann, and Jürgen R. Müller
Survival adjustment of mature dendritic cells by IL-15
PNAS 2005 102: 8662-8667; published online before print June 2 2005, 10.1073/pnas.0503360102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Jan Salomonsen, Maria Rathmann Sørensen, Denise A. Marston, Sally L. Rogers, Trevor Collen, Andrew van Hateren, Adrian L. Smith, Richard K. Beal, Karsten Skjødt, and Jim Kaufman
From The Cover: Two CD1 genes map to the chicken MHC, indicating that CD1 genes are ancient and likely to have been present in the primordial MHC
PNAS 2005 102: 8668-8673; published online before print June 6 2005, 10.1073/pnas.0409213102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  
See Commentary on page 8399

Marcia M. Miller, Carren Wang, Emilio Parisini, Ricardo D. Coletta, Ronald M. Goto, Stella Y. Lee, Duarte C. Barral, Maria Townes, Carme Roura-Mir, Heide L. Ford, Michael B. Brenner, and Christopher C. Dascher
From The Cover: Characterization of two avian MHC-like genes reveals an ancient origin of the CD1 family
PNAS 2005 102: 8674-8679; published online before print June 6 2005, 10.1073/pnas.0500105102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  
See Commentary on page 8399

Nir Modiano, Yanping E. Lu, and Peter Cresswell
Golgi targeting of human guanylate-binding protein-1 requires nucleotide binding, isoprenylation, and an IFN-{gamma}-inducible cofactor
PNAS 2005 102: 8680-8685; published online before print June 3 2005, 10.1073/pnas.0503227102 [Abstract] [Full Text] [Figures Only] [PDF]  

Peter J. Murray
The primary mechanism of the IL-10-regulated antiinflammatory response is to selectively inhibit transcription
PNAS 2005 102: 8686-8691; published online before print June 3 2005, 10.1073/pnas.0500419102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Medical Sciences

Konrad Urbanek, Daniele Torella, Farooq Sheikh, Antonella De Angelis, Daria Nurzynska, Furio Silvestri, C. Alberto Beltrami, Rossana Bussani, Antonio P. Beltrami, Federico Quaini, Roberto Bolli, Annarosa Leri, Jan Kajstura, and Piero Anversa
Myocardial regeneration by activation of multipotent cardiac stem cells in ischemic heart failure
PNAS 2005 102: 8692-8697; published online before print June 2 2005, 10.1073/pnas.0500169102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Christopher H. Evans, Paul D. Robbins, Steven C. Ghivizzani, Mary Chester Wasko, Matthew M. Tomaino, Richard Kang, Thomas A. Muzzonigro, Molly Vogt, Elaine M. Elder, Theresa L. Whiteside, Simon C. Watkins, and James H. Herndon
Gene transfer to human joints: Progress toward a gene therapy of arthritis
PNAS 2005 102: 8698-8703; published online before print June 6 2005, 10.1073/pnas.0502854102 [Abstract] [Full Text] [Figures Only] [PDF]  

Shin-ichi Harashima, Anne Clark, Michael R. Christie, and Abner Louis Notkins
The dense core transmembrane vesicle protein IA-2 is a regulator of vesicle number and insulin secretion
PNAS 2005 102: 8704-8709; published online before print June 6 2005, 10.1073/pnas.0408887102 [Abstract] [Full Text] [Figures Only] [PDF]  

Microbiology

Sébastien Guiral, Tim J. Mitchell, Bernard Martin, and Jean-Pierre Claverys
From The Cover: Competence-programmed predation of noncompetent cells in the human pathogen Streptococcus pneumoniae: Genetic requirements
PNAS 2005 102: 8710-8715; published online before print May 31 2005, 10.1073/pnas.0500879102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  
See Commentary on page 8401

Karen Sheader, Sue Vaughan, James Minchin, Katie Hughes, Keith Gull, and Gloria Rudenko
Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes
PNAS 2005 102: 8716-8721; published online before print June 3 2005, 10.1073/pnas.0501886102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Jeffrey G. Shannon, Dale Howe, and Robert A. Heinzen
Virulent Coxiella burnetii does not activate human dendritic cells: Role of lipopolysaccharide as a shielding molecule
PNAS 2005 102: 8722-8727; published online before print June 6 2005, 10.1073/pnas.0501863102 [Abstract] [Full Text] [Figures Only] [PDF]  

Gregory B. Melikyan, Richard J. O. Barnard, Levon G. Abrahamyan, Walther Mothes, and John A. T. Young
Imaging individual retroviral fusion events: From hemifusion to pore formation and growth
PNAS 2005 102: 8728-8733; published online before print June 3 2005, 10.1073/pnas.0501864102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Kenneth S. Chan, Paulo H. Verardi, Fatema A. Legrand, and Tilahun D. Yilma
Nef from pathogenic simian immunodeficiency virus is a negative factor for vaccinia virus
PNAS 2005 102: 8734-8739; published online before print June 1 2005, 10.1073/pnas.0503542102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE  

Neuroscience

Sakiko Okumoto, Loren L. Looger, Kristina D. Micheva, Richard J. Reimer, Stephen J Smith, and Wolf B. Frommer
Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors
PNAS 2005 102: 8740-8745; published online before print June 6 2005, 10.1073/pnas.0503274102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE  

Lina Yao, Krista McFarland, Peidong Fan, Zhan Jiang, Yuichiro Inoue, and Ivan Diamond
Activator of G protein signaling 3 regulates opiate activation of protein kinase A signaling and relapse of heroin-seeking behavior
PNAS 2005 102: 8746-8751; published online before print June 3 2005, 10.1073/pnas.0503419102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE  

Giorgio Brunelli, PierFranco Spano, Sergio Barlati, Bruno Guarneri, Alessandro Barbon, Roberto Bresciani, and Marina Pizzi
Glutamatergic reinnervation through peripheral nerve graft dictates assembly of glutamatergic synapses at rat skeletal muscle
PNAS 2005 102: 8752-8757; published online before print June 3 2005, 10.1073/pnas.0500530102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Pharmacology

Xiangdong Le, Daoyan Wei, Suyun Huang, Jack R. Lancaster, Jr., and Keping Xie
Nitric oxide synthase II suppresses the growth and metastasis of human cancer regardless of its up-regulation of protumor factors
PNAS 2005 102: 8758-8763; published online before print June 6 2005, 10.1073/pnas.0409581102 [Abstract] [Full Text] [Figures Only] [PDF]  

Johann Soret, Nadia Bakkour, Sophie Maire, Sébastien Durand, Latifa Zekri, Mathieu Gabut, Weronika Fic, Gilles Divita, Christian Rivalle, Daniel Dauzonne, Chi Hung Nguyen, Philippe Jeanteur, and Jamal Tazi
Selective modification of alternative splicing by indole derivatives that target serine-arginine-rich protein splicing factors
PNAS 2005 102: 8764-8769; published online before print June 6 2005, 10.1073/pnas.0409829102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Plant Biology

Akiko Sogo and Hiroshi Tobe
Intermittent pollen-tube growth in pistils of alders (Alnus)
PNAS 2005 102: 8770-8775; published online before print June 2 2005, 10.1073/pnas.0503081102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting figures]  

CORRECTIONS

Correction for Lim et al., Cyclin-dependent kinase 6 associates with the androgen receptor and enhances its transcriptional activity in prostate cancer cells, PNAS 2005 102:5156-5161 [Extract] [Full Text] [Figures Only] [PDF]  

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