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Table of Contents

August 16, 2005; 102 (33)  [Index By Author]  [Cover Photo]  [Masthead (PDF)]

FROM THE COVER

Morphological signaling of feather development

Mechanical stresses induce growth patterning

Geographic routing in social networks

Cofactor defines estrogen response domain

Evolution of rice centromeric DNA

IN THIS ISSUE

COMMENTARIES

NOBEL LECTURE

PERSPECTIVES

PROFILES

PHYSICAL SCIENCES
    Applied Physical Sciences
    Chemistry
    Computer Sciences
    Geology
    Physics

SOCIAL SCIENCES
    Anthropology
    Social Sciences

BIOLOGICAL SCIENCES
    Biochemistry
    Biophysics
    Cell Biology
    Developmental Biology
    Ecology
    Evolution
    Genetics

    Immunology
    Medical Sciences
    Microbiology
    Neuroscience
    Physiology
    Plant Biology
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IN THIS ISSUE

This Week in PNAS
PNAS 2005 102: 11569-11570. [Full Text] [Figures Only] [PDF]  

COMMENTARIES

Donald E. Ingber
Mechanical control of tissue growth: Function follows form
PNAS 2005 102: 11571-11572; published online before print August 9 2005, 10.1073/pnas.0505939102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 11594

R. Kelly Dawe
Centromere renewal and replacement in the plant kingdom
PNAS 2005 102: 11573-11574; published online before print August 9 2005, 10.1073/pnas.0505100102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 11793

NOBEL LECTURE

Irwin A. Rose
Ubiquitin at Fox Chase
PNAS 2005 102: 11575-11577; published online before print August 9 2005, 10.1073/pnas.0502921102 [Extract] [Full Text] [Figures Only] [PDF]  

PERSPECTIVES

Irwin A. Rose
Ubiquitin at Fox Chase
PNAS 2005 102: 11575-11577; published online before print August 9 2005, 10.1073/pnas.0502921102 [Extract] [Full Text] [Figures Only] [PDF]  

PROFILES

Nick Zagorski
Profile of Diane E. Griffin
PNAS 2005 102: 11578-11580; published online before print August 8 2005, 10.1073/pnas.0505531102 [Extract] [Full Text] [Figures Only] [PDF]  

PHYSICAL SCIENCES

Applied Physical Sciences

Hezy Cohen, Claude Nogues, Ron Naaman, and Danny Porath
Direct measurement of electrical transport through single DNA molecules of complex sequence
PNAS 2005 102: 11589-11593; published online before print August 8 2005, 10.1073/pnas.0505272102 [Abstract] [Full Text] [Figures Only] [PDF]  

Celeste M. Nelson, Ronald P. Jean, John L. Tan, Wendy F. Liu, Nathan J. Sniadecki, Alexander A. Spector, and Christopher S. Chen
From the Cover: Emergent patterns of growth controlled by multicellular form and mechanics
PNAS 2005 102: 11594-11599; published online before print July 27 2005, 10.1073/pnas.0502575102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  
See Commentary on page 11571

Chemistry

Nadine Wong Shi Kam, Michael O'Connell, Jeffrey A. Wisdom, and Hongjie Dai
Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction
PNAS 2005 102: 11600-11605; published online before print August 8 2005, 10.1073/pnas.0502680102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Masahiko Inouye, Reona Ikeda, Masayoshi Takase, Takashi Tsuri, and Junya Chiba
Single-nucleotide polymorphism detection with "wire-like" DNA probes that display quasi "on–off" digital action
PNAS 2005 102: 11606-11610; published online before print August 8 2005, 10.1073/pnas.0502078102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Edward Harder, Joel D. Eaves, Andrei Tokmakoff, and B. J. Berne
Polarizable molecules in the vibrational spectroscopy of water
PNAS 2005 102: 11611-11616; published online before print August 4 2005, 10.1073/pnas.0505206102 [Abstract] [Full Text] [Figures Only] [PDF]  

Valerie C. Clark, Christopher J. Raxworthy, Valérie Rakotomalala, Petra Sierwald, and Brian L. Fisher
Convergent evolution of chemical defense in poison frogs and arthropod prey between Madagascar and the Neotropics
PNAS 2005 102: 11617-11622; published online before print August 8 2005, 10.1073/pnas.0503502102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  

Computer Sciences

David Liben-Nowell, Jasmine Novak, Ravi Kumar, Prabhakar Raghavan, and Andrew Tomkins
From the Cover: Geographic routing in social networks
PNAS 2005 102: 11623-11628; published online before print August 4 2005, 10.1073/pnas.0503018102 [Abstract] [Full Text] [Figures Only] [PDF]  

Zach Solan, David Horn, Eytan Ruppin, and Shimon Edelman
Unsupervised learning of natural languages
PNAS 2005 102: 11629-11634; published online before print August 8 2005, 10.1073/pnas.0409746102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Geology

David W. Steadman, Paul S. Martin, Ross D. E. MacPhee, A. J. T. Jull, H. Gregory McDonald, Charles A. Woods, Manuel Iturralde-Vinent, and Gregory W. L. Hodgins
Asynchronous extinction of late Quaternary sloths on continents and islands
PNAS 2005 102: 11763-11768; published online before print August 5 2005, 10.1073/pnas.0502777102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Physics

E. Prodan and W. Kohn
Nearsightedness of electronic matter
PNAS 2005 102: 11635-11638; published online before print August 8 2005, 10.1073/pnas.0505436102 [Abstract] [Full Text] [Figures Only] [PDF]  

J. Daillant, E. Bellet-Amalric, A. Braslau, T. Charitat, G. Fragneto, F. Graner, S. Mora, F. Rieutord, and B. Stidder
Structure and fluctuations of a single floating lipid bilayer
PNAS 2005 102: 11639-11644; published online before print August 8 2005, 10.1073/pnas.0504588102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

SOCIAL SCIENCES

Anthropology

E. A. Hammel
Kinship-based politics and the optimal size of kin groups
PNAS 2005 102: 11951-11956; published online before print August 9 2005, 10.1073/pnas.0504647102 [Abstract] [Full Text] [Figures Only] [PDF]  

Social Sciences

David Liben-Nowell, Jasmine Novak, Ravi Kumar, Prabhakar Raghavan, and Andrew Tomkins
From the Cover: Geographic routing in social networks
PNAS 2005 102: 11623-11628; published online before print August 4 2005, 10.1073/pnas.0503018102 [Abstract] [Full Text] [Figures Only] [PDF]  

BIOLOGICAL SCIENCES

Biochemistry

Shane R. Wilkinson, S. Radhika Prathalingam, Martin C. Taylor, David Horn, and John M. Kelly
Vitamin C biosynthesis in trypanosomes: A role for the glycosome
PNAS 2005 102: 11645-11650; published online before print August 8 2005, 10.1073/pnas.0504251102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Josée Laganière, Geneviève Deblois, Céline Lefebvre, Alain R. Bataille, François Robert, and Vincent Giguère
From the Cover: Location analysis of estrogen receptor {alpha} target promoters reveals that FOXA1 defines a domain of the estrogen response
PNAS 2005 102: 11651-11656; published online before print August 8 2005, 10.1073/pnas.0505575102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Meredith M. Murr and Daniel E. Morse
Fractal intermediates in the self-assembly of silicatein filaments
PNAS 2005 102: 11657-11662; published online before print August 9 2005, 10.1073/pnas.0503968102 [Abstract] [Full Text] [Figures Only] [PDF]  

Nobumoto Watanabe, Harumi Arai, Jun-ichi Iwasaki, Masaaki Shiina, Kazuhiro Ogata, Tony Hunter, and Hiroyuki Osada
Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways
PNAS 2005 102: 11663-11668; published online before print August 5 2005, 10.1073/pnas.0500410102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Masaaki Sokabe, Ayuko Okada, Min Yao, Takashi Nakashima, and Isao Tanaka
Molecular basis of alanine discrimination in editing site
PNAS 2005 102: 11669-11674; published online before print August 8 2005, 10.1073/pnas.0502119102 [Abstract] [Full Text] [Figures Only] [PDF]  

Justyna Kanczewska, Sergio Marco, Caroline Vandermeeren, Olivier Maudoux, Jean-Louis Rigaud, and Marc Boutry
Activation of the plant plasma membrane H+-ATPase by phosphorylation and binding of 14-3-3 proteins converts a dimer into a hexamer
PNAS 2005 102: 11675-11680; published online before print August 4 2005, 10.1073/pnas.0504498102 [Abstract] [Full Text] [Figures Only] [PDF]  

Maria T. Bengoechea-Alonso, Tanel Punga, and Johan Ericsson
Hyperphosphorylation regulates the activity of SREBP1 during mitosis
PNAS 2005 102: 11681-11686; published online before print August 4 2005, 10.1073/pnas.0501494102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Marie Jidenko, Rikke C. Nielsen, Thomas Lykke-Møller Sørensen, Jesper V. Møller, Marc le Maire, Poul Nissen, and Christine Jaxel
Crystallization of a mammalian membrane protein overexpressed in Saccharomyces cerevisiae
PNAS 2005 102: 11687-11691; published online before print August 8 2005, 10.1073/pnas.0503986102 [Abstract] [Full Text] [Figures Only] [PDF]  

Biophysics

Troy Cellmer, Dusan Bratko, John M. Prausnitz, and Harvey Blanch
Protein-folding landscapes in multichain systems
PNAS 2005 102: 11692-11697; published online before print August 4 2005, 10.1073/pnas.0505342102 [Abstract] [Full Text] [Figures Only] [PDF]  

Bojan Zagrovic, Jan Lipfert, Eric J. Sorin, Ian S. Millett, Wilfred F. van Gunsteren, Sebastian Doniach, and Vijay S. Pande
Unusual compactness of a polyproline type II structure
PNAS 2005 102: 11698-11703; published online before print August 5 2005, 10.1073/pnas.0409693102 [Abstract] [Full Text] [Figures Only] [PDF]  

Marius Schmidt, Karin Nienhaus, Reinhard Pahl, Angela Krasselt, Spencer Anderson, Fritz Parak, G. Ulrich Nienhaus, and Vukica Srajer
Ligand migration pathway and protein dynamics in myoglobin: A time-resolved crystallographic study on L29W MbCO
PNAS 2005 102: 11704-11709; published online before print August 5 2005, 10.1073/pnas.0504932102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Asif Ladiwala, Kaushal Rege, Curtis M. Breneman, and Steven M. Cramer
A priori prediction of adsorption isotherm parameters and chromatographic behavior in ion-exchange systems
PNAS 2005 102: 11710-11715; published online before print August 4 2005, 10.1073/pnas.0408769102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Cell Biology

Celeste M. Nelson, Ronald P. Jean, John L. Tan, Wendy F. Liu, Nathan J. Sniadecki, Alexander A. Spector, and Christopher S. Chen
From the Cover: Emergent patterns of growth controlled by multicellular form and mechanics
PNAS 2005 102: 11594-11599; published online before print July 27 2005, 10.1073/pnas.0502575102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  
See Commentary on page 11571

Pilar Blancafort, Emily I. Chen, Beatriz Gonzalez, Sharon Bergquist, Andries Zijlstra, Daniel Guthy, Arndt Brachat, Ruud H. Brakenhoff, James P. Quigley, Dirk Erdmann, and Carlos F. Barbas, III
Genetic reprogramming of tumor cells by zinc finger transcription factors
PNAS 2005 102: 11716-11721; published online before print August 4 2005, 10.1073/pnas.0501162102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Helen H. N. Yan and C. Yan Cheng
Blood–testis barrier dynamics are regulated by an engagement/disengagement mechanism between tight and adherens junctions via peripheral adaptors
PNAS 2005 102: 11722-11727; published online before print August 5 2005, 10.1073/pnas.0503855102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE  

Jiang Zhu, Yi Zhang, Gerard J. Joe, Richard Pompetti, and Stephen G. Emerson
NF-Ya activates multiple hematopoietic stem cell (HSC) regulatory genes and promotes HSC self-renewal
PNAS 2005 102: 11728-11733; published online before print August 4 2005, 10.1073/pnas.0503405102 [Abstract] [Full Text] [Figures Only] [PDF]  

Developmental Biology

Matthew P. Harris, Scott Williamson, John F. Fallon, Hans Meinhardt, and Richard O. Prum
From the Cover: Molecular evidence for an activator–inhibitor mechanism in development of embryonic feather branching
PNAS 2005 102: 11734-11739; published online before print August 8 2005, 10.1073/pnas.0500781102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Yu-Wen Zhang, Yanli Su, Nathan Lanning, Pamela J. Swiatek, Roderick T. Bronson, Robert Sigler, Richard W. Martin, and George F. Vande Woude
Targeted disruption of Mig-6 in the mouse genome leads to early onset degenerative joint disease
PNAS 2005 102: 11740-11745; published online before print August 8 2005, 10.1073/pnas.0505171102 [Abstract] [Full Text] [Figures Only] [PDF]  

John R. Timmer, Tracy W. Mak, Katia Manova, Kathryn V. Anderson, and Lee Niswander
Tissue morphogenesis and vascular stability require the Frem2 protein, product of the mouse myelencephalic blebs gene
PNAS 2005 102: 11746-11750; published online before print August 8 2005, 10.1073/pnas.0505404102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures] OPEN ACCESS ARTICLE  

Anjang Tan, Hiromasa Tanaka, Toshiki Tamura, and Takahiro Shiotsuki
Precocious metamorphosis in transgenic silkworms overexpressing juvenile hormone esterase
PNAS 2005 102: 11751-11756; published online before print August 8 2005, 10.1073/pnas.0500954102 [Abstract] [Full Text] [Figures Only] [PDF]  

Christian E. Rocheleau, Agneta Rönnlund, Simon Tuck, and Meera V. Sundaram
Caenorhabditis elegans CNK-1 promotes Raf activation but is not essential for Ras/Raf signaling
PNAS 2005 102: 11757-11762; published online before print August 5 2005, 10.1073/pnas.0500937102 [Abstract] [Full Text] [Figures Only] [PDF]  

Ecology

Valerie C. Clark, Christopher J. Raxworthy, Valérie Rakotomalala, Petra Sierwald, and Brian L. Fisher
Convergent evolution of chemical defense in poison frogs and arthropod prey between Madagascar and the Neotropics
PNAS 2005 102: 11617-11622; published online before print August 8 2005, 10.1073/pnas.0503502102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  

David W. Steadman, Paul S. Martin, Ross D. E. MacPhee, A. J. T. Jull, H. Gregory McDonald, Charles A. Woods, Manuel Iturralde-Vinent, and Gregory W. L. Hodgins
Asynchronous extinction of late Quaternary sloths on continents and islands
PNAS 2005 102: 11763-11768; published online before print August 5 2005, 10.1073/pnas.0502777102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Evolution

R. Andrew Cameron, Suk Hen Chow, Kevin Berney, Tsz-Yeung Chiu, Qiu-Autumn Yuan, Alexander Krämer, Argelia Helguero, Andrew Ransick, Mirong Yun, and Eric H. Davidson
An evolutionary constraint: Strongly disfavored class of change in DNA sequence during divergence of cis-regulatory modules
PNAS 2005 102: 11769-11774; published online before print August 8 2005, 10.1073/pnas.0505291102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Andreas Wagner
Circuit topology and the evolution of robustness in two-gene circadian oscillators
PNAS 2005 102: 11775-11780; published online before print August 8 2005, 10.1073/pnas.0501094102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Irina R. Arkhipova and Matthew Meselson
Diverse DNA transposons in rotifers of the class Bdelloidea
PNAS 2005 102: 11781-11786; published online before print August 4 2005, 10.1073/pnas.0505333102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Genetics

Austen R. D. Ganley, Kouji Hayashi, Takashi Horiuchi, and Takehiko Kobayashi
Identifying gene-independent noncoding functional elements in the yeast ribosomal DNA by phylogenetic footprinting
PNAS 2005 102: 11787-11792; published online before print August 4 2005, 10.1073/pnas.0504905102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures] OPEN ACCESS ARTICLE  

Hye-Ran Lee, Wenli Zhang, Tim Langdon, Weiwei Jin, Huihuang Yan, Zhukuan Cheng, and Jiming Jiang
From The Cover: Chromatin immunoprecipitation cloning reveals rapid evolutionary patterns of centromeric DNA in Oryza species
PNAS 2005 102: 11793-11798; published online before print July 22 2005, 10.1073/pnas.0503863102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  
See Commentary on page 11573

Paola Bellosta, Toby Hulf, Soda Balla Diop, Fabrice Usseglio, Jacques Pradel, Denise Aragnol, and Peter Gallant
Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development
PNAS 2005 102: 11799-11804; published online before print August 8 2005, 10.1073/pnas.0408945102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Immunology

Anja K. Kriegeskorte, Friedemann E. Gebhardt, Simona Porcellini, Matthias Schiemann, Christian Stemberger, Tobias J. Franz, Katharina M. Huster, Leon N. Carayannopoulos, Wayne M. Yokoyama, Marco Colonna, Antonio G. Siccardi, Stefan Bauer, and Dirk H. Busch
NKG2D-independent suppression of T cell proliferation by H60 and MICA
PNAS 2005 102: 11805-11810; published online before print August 9 2005, 10.1073/pnas.0502026102 [Abstract] [Full Text] [Figures Only] [PDF]  

Simon C. Yue, Angela Shaulov, Ruojie Wang, Steven P. Balk, and Mark A. Exley
CD1d ligation on human monocytes directly signals rapid NF-{kappa}B activation and production of bioactive IL-12
PNAS 2005 102: 11811-11816; published online before print August 9 2005, 10.1073/pnas.0503366102 [Abstract] [Full Text] [Figures Only] [PDF]  

Divya J. Mekala, Rajshekhar S. Alli, and Terrence L. Geiger
IL-10-dependent infectious tolerance after the treatment of experimental allergic encephalomyelitis with redirected CD4+CD25+ T lymphocytes
PNAS 2005 102: 11817-11822; published online before print August 8 2005, 10.1073/pnas.0505445102 [Abstract] [Full Text] [Figures Only] [PDF]  

Jian Wang, Taku Yoshida, Fumio Nakaki, Hiroshi Hiai, Taku Okazaki, and Tasuku Honjo
Establishment of NOD-Pdcd1-/- mice as an efficient animal model of type I diabetes
PNAS 2005 102: 11823-11828; published online before print August 8 2005, 10.1073/pnas.0505497102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Diana Ronai, Maria Dolores Iglesias-Ussel, Manxia Fan, Marc J. Shulman, and Matthew D. Scharff
Complex regulation of somatic hypermutation by cis-acting sequences in the endogenous IgH gene in hybridoma cells
PNAS 2005 102: 11829-11834; published online before print August 8 2005, 10.1073/pnas.0505449102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Medical Sciences

W. Tapper, A. Collins, J. Gibson, N. Maniatis, S. Ennis, and N. E. Morton
A map of the human genome in linkage disequilibrium units
PNAS 2005 102: 11835-11839; published online before print August 9 2005, 10.1073/pnas.0505262102 [Abstract] [Full Text] [Figures Only] [PDF]  

Trent Nguyen, Aaron Hamby, and Stephen M. Massa
Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease mouse model
PNAS 2005 102: 11840-11845; published online before print August 8 2005, 10.1073/pnas.0502177102 [Abstract] [Full Text] [Figures Only] [PDF]  

Jane Tian, Kazuki Ishibashi, Kazuko Ishibashi, Karen Reiser, Rhonda Grebe, Shyam Biswal, Peter Gehlbach, and James T. Handa
Advanced glycation endproduct-induced aging of the retinal pigment epithelium and choroid: A comprehensive transcriptional response
PNAS 2005 102: 11846-11851; published online before print August 4 2005, 10.1073/pnas.0504759102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables] OPEN ACCESS ARTICLE  

Gerlinde Wernig, Viktor Janzen, Ralf Schäfer, Margit Zweyer, Ulrich Knauf, Oliver Hoegemeier, Rustam R. Mundegar, Stefan Garbe, Sebastian Stier, Thomas Franz, Marius Wernig, and Anton Wernig
The vast majority of bone-marrow-derived cells integrated into mdx muscle fibers are silent despite long-term engraftment
PNAS 2005 102: 11852-11857; published online before print August 5 2005, 10.1073/pnas.0502507102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Anjali Jain, Charles A. Tindell, Isett Laux, Jacob B. Hunter, John Curran, Anna Galkin, Daniel E. Afar, Nina Aronson, Steven Shak, Ronald B. Natale, and David B. Agus
Epithelial membrane protein-1 is a biomarker of gefitinib resistance
PNAS 2005 102: 11858-11863; published online before print August 8 2005, 10.1073/pnas.0502113102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Qing-Rong Liu, Tomas Drgon, Donna Walther, Catherine Johnson, Oxanna Poleskaya, Judith Hess, and George R. Uhl
Pooled association genome scanning: Validation and use to identify addiction vulnerability loci in two samples
PNAS 2005 102: 11864-11869; published online before print August 9 2005, 10.1073/pnas.0500329102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Biljana Musicki, Melissa F. Kramer, Robyn E. Becker, and Arthur L. Burnett
Inactivation of phosphorylated endothelial nitric oxide synthase (Ser-1177) by O-GlcNAc in diabetes-associated erectile dysfunction
PNAS 2005 102: 11870-11875; published online before print August 5 2005, 10.1073/pnas.0502488102 [Abstract] [Full Text] [Figures Only] [PDF]  

Microbiology

Chien-Hsiung Pan, Alexandra Valsamakis, Teresa Colella, Nitya Nair, Robert J. Adams, Fernando P. Polack, Catherine E. Greer, Silvia Perri, John M. Polo, and Diane E. Griffin
Inaugural Article by a Recently Elected Academy Member:
Inaugural Article: Modulation of disease, T cell responses, and measles virus clearance in monkeys vaccinated with H-encoding alphavirus replicon particles
PNAS 2005 102: 11581-11588; published online before print July 21 2005, 10.1073/pnas.0504592102 [Abstract] [Full Text] [Figures Only] [PDF]  

Graham Simmons, Dhaval N. Gosalia, Andrew J. Rennekamp, Jacqueline D. Reeves, Scott L. Diamond, and Paul Bates
Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry
PNAS 2005 102: 11876-11881; published online before print August 4 2005, 10.1073/pnas.0505577102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Dali Liu, Bryan W. Lepore, Gregory A. Petsko, Pei W. Thomas, Everett M. Stone, Walter Fast, and Dagmar Ringe
Three-dimensional structure of the quorum-quenching N-acyl homoserine lactone hydrolase from Bacillus thuringiensis
PNAS 2005 102: 11882-11887; published online before print August 8 2005, 10.1073/pnas.0505255102 [Abstract] [Full Text] [Figures Only] [PDF]  

Neuroscience

Martin Lévesque and André Parent
The striatofugal fiber system in primates: A reevaluation of its organization based on single-axon tracing studies
PNAS 2005 102: 11888-11893; published online before print August 8 2005, 10.1073/pnas.0502710102 [Abstract] [Full Text] [Figures Only] [PDF]  

D. S. Roberts, Y. H. Raol, S. Bandyopadhyay, I. V. Lund, E. C. Budreck, M. A. Passini, J. H. Wolfe, A. R. Brooks-Kayal, and S. J. Russek
Egr3 stimulation of GABRA4 promoter activity as a mechanism for seizure-induced up-regulation of GABAA receptor {alpha}4 subunit expression
PNAS 2005 102: 11894-11899; published online before print August 9 2005, 10.1073/pnas.0501434102 [Abstract] [Full Text] [Figures Only] [PDF]  

G. Malek, L. V. Johnson, B. E. Mace, P. Saloupis, D. E. Schmechel, D. W. Rickman, C. A. Toth, P. M. Sullivan, and C. Bowes Rickman
Apolipoprotein E allele-dependent pathogenesis: A model for age-related retinal degeneration
PNAS 2005 102: 11900-11905; published online before print August 3 2005, 10.1073/pnas.0503015102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Malgorzata Marjanska, Geoffrey L. Curran, Thomas M. Wengenack, Pierre-Gilles Henry, Robin L. Bliss, Joseph F. Poduslo, Clifford R. Jack, Jr., Kâmil Ugurbil, and Michael Garwood
Monitoring disease progression in transgenic mouse models of Alzheimer's disease with proton magnetic resonance spectroscopy
PNAS 2005 102: 11906-11910; published online before print August 9 2005, 10.1073/pnas.0505513102 [Abstract] [Full Text] [Figures Only] [PDF]  

Physiology

Liyun Wang, Yilin Wang, Yuefeng Han, Scott C. Henderson, Robert J. Majeska, Sheldon Weinbaum, and Mitchell B. Schaffler
In situ measurement of solute transport in the bone lacunar-canalicular system
PNAS 2005 102: 11911-11916; published online before print August 8 2005, 10.1073/pnas.0505193102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Appendix]  

Luiz F. Leomil Coelho, Gabriel Magno de Freitas Almeida, Franck J. D. Mennechet, Anne Blangy, and Gilles Uzé
Interferon-{alpha} and -{beta} differentially regulate osteoclastogenesis: Role of differential induction of chemokine CXCL11 expression
PNAS 2005 102: 11917-11922; published online before print August 4 2005, 10.1073/pnas.0502188102 [Abstract] [Full Text] [Figures Only] [PDF]  

James F. Gillooly, Andrew P. Allen, James H. Brown, James J. Elser, Carlos Martinez del Rio, Van M. Savage, Geoffrey B. West, William H. Woodruff, and H. Arthur Woods
The metabolic basis of whole-organism RNA and phosphorus content
PNAS 2005 102: 11923-11927; published online before print August 9 2005, 10.1073/pnas.0504756102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Plant Biology

N. Baumberger and D. C. Baulcombe
Arabidopsis ARGONAUTE1 is an RNA Slicer that selectively recruits microRNAs and short interfering RNAs
PNAS 2005 102: 11928-11933; published online before print August 4 2005, 10.1073/pnas.0505461102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Materials and Methods] OPEN ACCESS ARTICLE  

Julie Misson, Kashchandra G. Raghothama, Ajay Jain, Juliette Jouhet, Maryse A. Block, Richard Bligny, Philippe Ortet, Audrey Creff, Shauna Somerville, Norbert Rolland, Patrick Doumas, Philippe Nacry, Luis Herrerra-Estrella, Laurent Nussaume, and Marie-Christine Thibaud
A genome-wide transcriptional analysis using Arabidopsis thaliana Affymetrix gene chips determined plant responses to phosphate deprivation
PNAS 2005 102: 11934-11939; published online before print August 5 2005, 10.1073/pnas.0505266102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Asuka Nishimura, Motoyuki Ashikari, Shaoyang Lin, Tomonori Takashi, Enrique R. Angeles, Toshio Yamamoto, and Makoto Matsuoka
Isolation of a rice regeneration quantitative trait loci gene and its application to transformation systems
PNAS 2005 102: 11940-11944; published online before print August 9 2005, 10.1073/pnas.0504220102 [Abstract] [Full Text] [Figures Only] [PDF]  

Insoon Kim, Ken Kobayashi, Euna Cho, and Patricia C. Zambryski
Subdomains for transport via plasmodesmata corresponding to the apical–basal axis are established during Arabidopsis embryogenesis
PNAS 2005 102: 11945-11950; published online before print August 8 2005, 10.1073/pnas.0505622102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

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