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IN THIS ISSUE

PNAS 2005 102: 14477-14478. [Full Text] [Figures Only] [PDF]  

COMMENTARIES

Karla Holmboe and Mark H. Johnson

Educating executive attention
PNAS 2005 102: 14479-14480; published online before print October 3 2005, 10.1073/pnas.0507522102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 14931

Robert K. Slany

Chromatin control of gene expression: Mixed-lineage leukemia methyltransferase SETs the stage for transcription
PNAS 2005 102: 14481-14482; published online before print October 3 2005, 10.1073/pnas.0507401102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 14765

Laurence L. Brunton

A positive feedback loop contributes to the deleterious effects of angiotensin
PNAS 2005 102: 14483-14484; published online before print October 3 2005, 10.1073/pnas.0507070102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 14771

Jonathan H. LeBowitz

A breach in the blood-brain barrier
PNAS 2005 102: 14485-14486; published online before print October 3 2005, 10.1073/pnas.0507523102 [Extract] [Full Text] [PDF]  
See companion article on page 14777

Robert B. Jackson and Esteban G. Jobbágy

From icy roads to salty streams
PNAS 2005 102: 14487-14488; published online before print October 3 2005, 10.1073/pnas.0507389102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 13517 in issue 38 of volume 102

PHYSICAL SCIENCES

Applied Mathematics

Dmitri Bratsun, Dmitri Volfson, Lev S. Tsimring, and Jeff Hasty

Delay-induced stochastic oscillations in gene regulation
PNAS 2005 102: 14593-14598; published online before print September 30 2005, 10.1073/pnas.0503858102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Engineering

Yong Zhu and Horacio D. Espinosa

An electromechanical material testing system for in situ electron microscopy and applications
PNAS 2005 102: 14503-14508; published online before print September 29 2005, 10.1073/pnas.0506544102 [Abstract] [Full Text] [Figures Only] [PDF]  

Kjirste C. Morrell, W. Andrew Hodge, David E. Krebs, and Robert W. Mann

Corroboration of in vivo cartilage pressures with implications for synovial joint tribology and osteoarthritis causation
PNAS 2005 102: 14819-14824; published online before print October 3 2005, 10.1073/pnas.0507117102 [Abstract] [Full Text] [Figures Only] [PDF]  

SOCIAL SCIENCES

BIOLOGICAL SCIENCES

Biochemistry

Moritoshi Sato, Naoki Hida, and Yoshio Umezawa

Imaging the nanomolar range of nitric oxide with an amplifier-coupled fluorescent indicator in living cells
PNAS 2005 102: 14515-14520; published online before print September 21 2005, 10.1073/pnas.0505136102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Nobutaka Numoto, Taro Nakagawa, Akiko Kita, Yuichi Sasayama, Yoshihiro Fukumori, and Kunio Miki

Structure of an extracellular giant hemoglobin of the gutless beard worm Oligobrachia mashikoi
PNAS 2005 102: 14521-14526; published online before print October 3 2005, 10.1073/pnas.0501541102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

John S. Allingham, Angela Zampella, Maria Valeria D'Auria, and Ivan Rayment

Structures of microfilament destabilizing toxins bound to actin provide insight into toxin design and activity
PNAS 2005 102: 14527-14532; published online before print September 28 2005, 10.1073/pnas.0502089102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Krishnamurthy Malathi, Jayashree M. Paranjape, Elena Bulanova, Minsub Shim, Jeanna M. Guenther-Johnson, Pieter W. Faber, Thomas E. Eling, Bryan R. G. Williams, and Robert H. Silverman A transcriptional signaling pathway in the IFN system mediated by 2'-5'-oligoadenylate activation of RNase L PNAS 2005 102: 14533-14538; published online before print October 3 2005, 10.1073/pnas.0507551102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables] OPEN ACCESS ARTICLE

Marylynn Snyder, Wei He, and J. Jillian Zhang

The DNA replication factor MCM5 is essential for Stat1-mediated transcriptional activation
PNAS 2005 102: 14539-14544; published online before print September 30 2005, 10.1073/pnas.0507479102 [Abstract] [Full Text] [Figures Only] [PDF]  

Nora S. Green, Ted R. Foss, and Jeffery W. Kelly

Genistein, a natural product from soy, is a potent inhibitor of transthyretin amyloidosis
PNAS 2005 102: 14545-14550; published online before print September 29 2005, 10.1073/pnas.0501609102 [Abstract] [Full Text] [Figures Only] [PDF]  

Fang Xu, Scott D. Rychnovsky, Jitendra D. Belani, Helen H. Hobbs, Jonathan C. Cohen, and Robert B. Rawson Dual roles for cholesterol in mammalian cells PNAS 2005 102: 14551-14556; published online before print September 30 2005, 10.1073/pnas.0503590102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Seung Hun Cha, Zhiyuan Hu, Shigeru Chohnan, and M. Daniel Lane

Inhibition of hypothalamic fatty acid synthase triggers rapid activation of fatty acid oxidation in skeletal muscle
PNAS 2005 102: 14557-14562; published online before print October 3 2005, 10.1073/pnas.0507300102 [Abstract] [Full Text] [Figures Only] [PDF]  

Biophysics

Corey J. Wilson, Payel Das, Cecilia Clementi, Kathleen S. Matthews, and Pernilla Wittung-Stafshede

The experimental folding landscape of monomeric lactose repressor, a large two-domain protein, involves two kinetic intermediates
PNAS 2005 102: 14563-14568; published online before print October 3 2005, 10.1073/pnas.0505808102 [Abstract] [Full Text] [Figures Only] [PDF]  

Payel Das, Corey J. Wilson, Giovanni Fossati, Pernilla Wittung-Stafshede, Kathleen S. Matthews, and Cecilia Clementi

Characterization of the folding landscape of monomeric lactose repressor: Quantitative comparison of theory and experiment
PNAS 2005 102: 14569-14574; published online before print October 3 2005, 10.1073/pnas.0505844102 [Abstract] [Full Text] [Figures Only] [PDF]  

Tongqing Zhou, Dean H. Hamer, Wayne A. Hendrickson, Quentin J. Sattentau, and Peter D. Kwong Interfacial metal and antibody recognition PNAS 2005 102: 14575-14580; published online before print September 29 2005, 10.1073/pnas.0507267102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure] OPEN ACCESS ARTICLE

I-Jin Lin, Erika B. Gebel, Timothy E. Machonkin, William M. Westler, and John L. Markley Changes in hydrogen-bond strengths explain reduction potentials in 10 rubredoxin variants PNAS 2005 102: 14581-14586; published online before print September 30 2005, 10.1073/pnas.0505521102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables] OPEN ACCESS ARTICLE

Natalija Backmann, Christian Zahnd, Francois Huber, Alexander Bietsch, Andreas Plückthun, Hans-Peter Lang, Hans-Joachim Güntherodt, Martin Hegner, and Christoph Gerber

A label-free immunosensor array using single-chain antibody fragments
PNAS 2005 102: 14587-14592; published online before print September 28 2005, 10.1073/pnas.0504917102 [Abstract] [Full Text] [Figures Only] [PDF]  

Dmitri Bratsun, Dmitri Volfson, Lev S. Tsimring, and Jeff Hasty

Delay-induced stochastic oscillations in gene regulation
PNAS 2005 102: 14593-14598; published online before print September 30 2005, 10.1073/pnas.0503858102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Cell Biology

Shinji Makino, Geoffrey G. Whitehead, Ching-Ling Lien, Soo Kim, Payal Jhawar, Akane Kono, Yasushi Kawata, and Mark T. Keating

Heat-shock protein 60 is required for blastema formation and maintenance during regeneration
PNAS 2005 102: 14599-14604; published online before print October 4 2005, 10.1073/pnas.0507408102 [Abstract] [Full Text] [Figures Only] [PDF]  

Jing Zhang and Harvey F. Lodish

Identification of K-ras as the major regulator for cytokine-dependent Akt activation in erythroid progenitors in vivo
PNAS 2005 102: 14605-14610; published online before print October 3 2005, 10.1073/pnas.0507446102 [Abstract] [Full Text] [Figures Only] [PDF]  

Zuyao Ni, Elizabeth Karaskov, Tao Yu, Steven M. Callaghan, Sandy Der, David S. Park, Zhaodong Xu, Samantha G. Pattenden, and Rod Bremner

Apical role for BRG1 in cytokine-induced promoter assembly
PNAS 2005 102: 14611-14616; published online before print September 29 2005, 10.1073/pnas.0503070102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jeremy Gunawardena

Multisite protein phosphorylation makes a good threshold but can be a poor switch
PNAS 2005 102: 14617-14622; published online before print September 29 2005, 10.1073/pnas.0507322102 [Abstract] [Full Text] [Figures Only] [PDF]  

Kuan Onn Tan, Nai Yang Fu, Sunil K. Sukumaran, Shing-Leng Chan, Jiunn Hian Kang, Kar Lai Poon, Bin Shun Chen, and Victor C. Yu MAP-1 is a mitochondrial effector of Bax PNAS 2005 102: 14623-14628; published online before print September 30 2005, 10.1073/pnas.0503524102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Annalisa Frattini, Harry C. Blair, Maria Grazia Sacco, Francesco Cerisoli, Francesca Faggioli, Enrica Mira Catò, Alessandra Pangrazio, Antonio Musio, Francesca Rucci, Cristina Sobacchi, Allison C. Sharrow, Sara E. Kalla, Maria Grazia Bruzzone, Roberto Colombo, Maria Cristina Magli, Paolo Vezzoni, and Anna Villa

Rescue of ATPa3-deficient murine malignant osteopetrosis by hematopoietic stem cell transplantation in utero
PNAS 2005 102: 14629-14634; published online before print September 29 2005, 10.1073/pnas.0507637102 [Abstract] [Full Text] [Figures Only] [PDF]  

Emilie Jacque, Thierry Tchenio, Guillaume Piton, Paul-Henri Romeo, and Véronique Baud

RelA repression of RelB activity induces selective gene activation downstream of TNF receptors
PNAS 2005 102: 14635-14640; published online before print September 28 2005, 10.1073/pnas.0507342102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Hongning Zhou, Vladimir N. Ivanov, Joseph Gillespie, Charles R. Geard, Sally A. Amundson, David J. Brenner, Zengliang Yu, Howard B. Lieberman, and Tom K. Hei

Mechanism of radiation-induced bystander effect: Role of the cyclooxygenase-2 signaling pathway
PNAS 2005 102: 14641-14646; published online before print October 3 2005, 10.1073/pnas.0505473102 [Abstract] [Full Text] [Figures Only] [PDF]  

Pierre Cosson, Mariella Ravazzola, Oleg Varlamov, Thomas H. Söllner, Maurizio Di Liberto, Allen Volchuk, James E. Rothman, and Lelio Orci

Dynamic transport of SNARE proteins in the Golgi apparatus
PNAS 2005 102: 14647-14652; published online before print September 30 2005, 10.1073/pnas.0507394102 [Abstract] [Full Text] [Figures Only] [PDF]  

Developmental Biology

Gerard M. J. Beaudoin, III, Jeanne M. Sisk, Pierre A. Coulombe, and Catherine C. Thompson

Hairless triggers reactivation of hair growth by promoting Wnt signaling
PNAS 2005 102: 14653-14658; published online before print September 29 2005, 10.1073/pnas.0507609102 [Abstract] [Full Text] [Figures Only] [PDF]  

Satyajit K. Karnik, Christina M. Hughes, Xueying Gu, Orit Rozenblatt-Rosen, Graeme W. McLean, Yue Xiong, Matthew Meyerson, and Seung K. Kim

Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27^Kip1 and p18^INK4c
PNAS 2005 102: 14659-14664; published online before print September 29 2005, 10.1073/pnas.0503484102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Haruhiko Akiyama, Jung-Eun Kim, Kazuhisa Nakashima, Gener Balmes, Naomi Iwai, Jian Min Deng, Zhaoping Zhang, James F. Martin, Richard R. Behringer, Takashi Nakamura, and Benoit de Crombrugghe Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors PNAS 2005 102: 14665-14670; published online before print October 3 2005, 10.1073/pnas.0504750102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure] OPEN ACCESS ARTICLE

Aphrodite Bilioni, Gavin Craig, Caroline Hill, and Helen McNeill Iroquois transcription factors recognize a unique motif to mediate transcriptional repression in vivo PNAS 2005 102: 14671-14676; published online before print October 3 2005, 10.1073/pnas.0502480102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Stéphanie Claudinot, Michael Nicolas, Hideo Oshima, Ariane Rochat, and Yann Barrandon From The Cover: Long-term renewal of hair follicles from clonogenic multipotent stem cells PNAS 2005 102: 14677-14682; published online before print October 3 2005, 10.1073/pnas.0507250102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]

Environmental Sciences

Christopher A. Francis, Kathryn J. Roberts, J. Michael Beman, Alyson E. Santoro, and Brian B. Oakley

Ubiquity and diversity of ammonia-oxidizing archaea in water columns and sediments of the ocean
PNAS 2005 102: 14683-14688; published online before print September 26 2005, 10.1073/pnas.0506625102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Evolution

David M. Spooner, Karen McLean, Gavin Ramsay, Robbie Waugh, and Glenn J. Bryan

A single domestication for potato based on multilocus amplified fragment length polymorphism genotyping
PNAS 2005 102: 14694-14699; published online before print October 3 2005, 10.1073/pnas.0507400102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Data Matrices]  

Ward F. Odenwald, Wayne Rasband, Alexander Kuzin, and Thomas Brody EVOPRINTER, a multigenomic comparative tool for rapid identification of functionally important DNA PNAS 2005 102: 14700-14705; published online before print October 3 2005, 10.1073/pnas.0506915102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Erik B. Dopman, Luisa Pérez, Steven M. Bogdanowicz, and Richard G. Harrison

Consequences of reproductive barriers for genealogical discordance in the European corn borer
PNAS 2005 102: 14706-14711; published online before print October 3 2005, 10.1073/pnas.0502054102 [Abstract] [Full Text] [Figures Only] [PDF]  

Ying Tan, Anne D. Yoder, Nayuta Yamashita, and Wen-Hsiung Li

Evidence from opsin genes rejects nocturnality in ancestral primates
PNAS 2005 102: 14712-14716; published online before print September 28 2005, 10.1073/pnas.0507042102 [Abstract] [Full Text] [Figures Only] [PDF]  

Genetics

Malek Faham, Jianbiao Zheng, Martin Moorhead, Hossein Fakhrai-Rad, Eugeni Namsaraev, Kee Wong, Zhiyong Wang, Shu G. Chow, Liana Lee, Kent Suyenaga, Jennifer Reichert, Andrew Boudreau, James Eberle, Carsten Bruckner, Maneesh Jain, George Karlin-Neumann, Hywel B. Jones, Thomas D. Willis, Joseph D. Buxbaum, and Ronald W. Davis

Multiplexed variation scanning for 1,000 amplicons in hundreds of patients using mismatch repair detection (MRD) on tag arrays
PNAS 2005 102: 14717-14722; published online before print October 3 2005, 10.1073/pnas.0506677102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  

Immunology

Olivier Thaunat, Anne-Christine Field, Jianping Dai, Liliane Louedec, Natacha Patey, Marie-Françoise Bloch, Chantal Mandet, Marie-France Belair, Patrick Bruneval, Olivier Meilhac, Blanche Bellon, Etienne Joly, Jean-Baptiste Michel, and Antonino Nicoletti

Lymphoid neogenesis in chronic rejection: Evidence for a local humoral alloimmune response
PNAS 2005 102: 14723-14728; published online before print September 28 2005, 10.1073/pnas.0507223102 [Abstract] [Full Text] [Figures Only] [PDF]  

Ngoc P. Ly, Katsumi Komatsuzaki, Iain P. Fraser, Anita A. Tseng, Parthak Prodhan, Kathryn J. Moore, and T. Bernard Kinane

Netrin-1 inhibits leukocyte migration in vitro and in vivo
PNAS 2005 102: 14729-14734; published online before print October 3 2005, 10.1073/pnas.0506233102 [Abstract] [Full Text] [Figures Only] [PDF]  

Zhibin Chen, Christophe Benoist, and Diane Mathis

How defects in central tolerance impinge on a deficiency in regulatory T cells
PNAS 2005 102: 14735-14740; published online before print October 3 2005, 10.1073/pnas.0507014102 [Abstract] [Full Text] [Figures Only] [PDF]  

Jena D. French, Christina L. Roark, Willi K. Born, and Rebecca L. O'Brien T cell homeostasis is established in competition with T cells and NK cells PNAS 2005 102: 14741-14746; published online before print October 3 2005, 10.1073/pnas.0507520102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Myriam Baratin, Sophie Roetynck, Catherine Lépolard, Christine Falk, Serge Sawadogo, Satoshi Uematsu, Shizuo Akira, Bernhard Ryffel, Jean-Gérard Tiraby, Lena Alexopoulou, Carsten J. Kirschning, Jürg Gysin, Eric Vivier, and Sophie Ugolini

Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparum
PNAS 2005 102: 14747-14752; published online before print October 3 2005, 10.1073/pnas.0507355102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Medical Sciences

Stephen S. C. Chim, Yu K. Tong, Rossa W. K. Chiu, Tze K. Lau, Tse N. Leung, Lisa Y. S. Chan, Cees B. M. Oudejans, Chunming Ding, and Y. M. Dennis Lo

Detection of the placental epigenetic signature of the maspin gene in maternal plasma
PNAS 2005 102: 14753-14758; published online before print October 3 2005, 10.1073/pnas.0503335102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Michael D. Miller, Romas Geleziunas, Elisabetta Bianchi, Simon Lennard, Renee Hrin, Hangchun Zhang, Meiqing Lu, Zhiqiang An, Paolo Ingallinella, Marco Finotto, Marco Mattu, Adam C. Finnefrock, David Bramhill, James Cook, Debra M. Eckert, Richard Hampton, Mayuri Patel, Stephen Jarantow, Joseph Joyce, Gennaro Ciliberto, Riccardo Cortese, Ping Lu, William Strohl, William Schleif, Michael McElhaugh, Steven Lane, Christopher Lloyd, David Lowe, Jane Osbourn, Tristan Vaughan, Emilio Emini, Gaetano Barbato, Peter S. Kim, Daria J. Hazuda, John W. Shiver, and Antonello Pessi

A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope
PNAS 2005 102: 14759-14764; published online before print October 3 2005, 10.1073/pnas.0506927102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Thomas A. Milne, Yali Dou, Mary Ellen Martin, Hugh W. Brock, Robert G. Roeder, and Jay L. Hess From The Cover: MLL associates specifically with a subset of transcriptionally active target genes PNAS 2005 102: 14765-14770; published online before print September 30 2005, 10.1073/pnas.0503630102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]   See Commentary on page 14481

Bo Ding, Jun-ichi Abe, Heng Wei, Haodong Xu, Wenyi Che, Toru Aizawa, Weimin Liu, Carlos A. Molina, Junichi Sadoshima, Burns C. Blaxall, Bradford C. Berk, and Chen Yan

A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis
PNAS 2005 102: 14771-14776; published online before print September 26 2005, 10.1073/pnas.0506489102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  
See Commentary on page 14483

Carole Vogler, Beth Levy, Jeffrey H. Grubb, Nancy Galvin, Yun Tan, Emil Kakkis, Nadine Pavloff, and William S. Sly From The Cover: Overcoming the blood-brain barrier with high-dose enzyme replacement therapy in murine mucopolysaccharidosis VII PNAS 2005 102: 14777-14782; published online before print September 14 2005, 10.1073/pnas.0506892102 [Abstract] [Full Text] [Figures Only] [PDF]   See Commentary on page 14485

Robert J. C. Gilbert, Lucy Beales, Donatienne Blond, Martha N. Simon, Beth Y. Lin, Francis V. Chisari, David I. Stuart, and David J. Rowlands

Hepatitis B small surface antigen particles are octahedral
PNAS 2005 102: 14783-14788; published online before print October 3 2005, 10.1073/pnas.0505062102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Hakon Hakonarson, Unnur S. Bjornsdottir, Eva Halapi, Jonathan Bradfield, Florian Zink, Magali Mouy, Hildur Helgadottir, Asta S. Gudmundsdottir, Hjalti Andrason, Asdis E. Adalsteinsdottir, Kristleifur Kristjansson, Illugi Birkisson, Thor Arnason, Margret Andresdottir, David Gislason, Thorarinn Gislason, Jeffrey R. Gulcher, and Kari Stefansson

Profiling of genes expressed in peripheral blood mononuclear cells predicts glucocorticoid sensitivity in asthma patients
PNAS 2005 102: 14789-14794; published online before print October 3 2005, 10.1073/pnas.0409904102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Mei Li, Nadia Messaddeq, Marius Teletin, Jean-Louis Pasquali, Daniel Metzger, and Pierre Chambon

Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin
PNAS 2005 102: 14795-14800; published online before print September 30 2005, 10.1073/pnas.0507385102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Timothy J. McMahon, Gregory S. Ahearn, Martin P. Moya, Andrew J. Gow, Yuh-Chin T. Huang, Benjamin P. Luchsinger, Raphael Nudelman, Yun Yan, Abigail D. Krichman, Thomas M. Bashore, Robert M. Califf, David J. Singel, Claude A. Piantadosi, Victor F. Tapson, and Jonathan S. Stamler

A nitric oxide processing defect of red blood cells created by hypoxia: Deficiency of S-nitrosohemoglobin in pulmonary hypertension
PNAS 2005 102: 14801-14806; published online before print October 3 2005, 10.1073/pnas.0506957102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Mikulas Popovic, Klara Tenner-Racz, Colleen Pelser, Hans-Jurgen Stellbrink, Jan van Lunzen, George Lewis, Vaniambadi S. Kalyanaraman, Robert C. Gallo, and Paul Racz

Persistence of HIV-1 structural proteins and glycoproteins in lymph nodes of patients under highly active antiretroviral therapy
PNAS 2005 102: 14807-14812; published online before print September 30 2005, 10.1073/pnas.0506857102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Arshi Malik, Farrukh Afaq, Sami Sarfaraz, Vaqar M. Adhami, Deeba N. Syed, and Hasan Mukhtar

Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer
PNAS 2005 102: 14813-14818; published online before print September 28 2005, 10.1073/pnas.0505870102 [Abstract] [Full Text] [Figures Only] [PDF]  

Kjirste C. Morrell, W. Andrew Hodge, David E. Krebs, and Robert W. Mann

Corroboration of in vivo cartilage pressures with implications for synovial joint tribology and osteoarthritis causation
PNAS 2005 102: 14819-14824; published online before print October 3 2005, 10.1073/pnas.0507117102 [Abstract] [Full Text] [Figures Only] [PDF]  

Maria Grazia Borrello, Luisella Alberti, Andrew Fischer, Debora Degl'Innocenti, Cristina Ferrario, Manuela Gariboldi, Federica Marchesi, Paola Allavena, Angela Greco, Paola Collini, Silvana Pilotti, Giuliana Cassinelli, Paola Bressan, Laura Fugazzola, Alberto Mantovani, and Marco A. Pierotti

Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene
PNAS 2005 102: 14825-14830; published online before print October 3 2005, 10.1073/pnas.0503039102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Microbiology

Alon M. Levy, Oren Gilad, Liang Xia, Yoshihiro Izumiya, Jonathan Choi, Anya Tsalenko, Zohar Yakhini, Richard Witter, Lucy Lee, Carol J. Cardona, and Hsing-Jien Kung

Marek's disease virus Meq transforms chicken cells via the v-Jun transcriptional cascade: A converging transforming pathway for avian oncoviruses
PNAS 2005 102: 14831-14836; published online before print October 3 2005, 10.1073/pnas.0506849102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Luisa M. Stamm, Melissa A. Pak, J. Hiroshi Morisaki, Scott B. Snapper, Klemens Rottner, Silvia Lommel, and Eric J. Brown Role of the WASP family proteins for Mycobacterium marinum actin tail formation PNAS 2005 102: 14837-14842; published online before print September 30 2005, 10.1073/pnas.0504663102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures] OPEN ACCESS ARTICLE

Hongbaek Cho and Stephen C. Winans

VirA and VirG activate the Ti plasmid repABC operon, elevating plasmid copy number in response to wound-released chemical signals
PNAS 2005 102: 14843-14848; published online before print September 29 2005, 10.1073/pnas.0503458102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Lionel Berthoux, Sarah Sebastian, Elena Sokolskaja, and Jeremy Luban Cyclophilin A is required for TRIM5-mediated resistance to HIV-1 in Old World monkey cells PNAS 2005 102: 14849-14853; published online before print October 3 2005, 10.1073/pnas.0505659102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Neuroscience

Yosuke Nagasaka, Karin Dillner, Hayao Ebise, Reiji Teramoto, Hiroyuki Nakagawa, Lena Lilius, Karin Axelman, Charlotte Forsell, Akira Ito, Bengt Winblad, Toru Kimura, and Caroline Graff

A unique gene expression signature discriminates familial Alzheimer's disease mutation carriers from their wild-type siblings
PNAS 2005 102: 14854-14859; published online before print September 30 2005, 10.1073/pnas.0504178102 [Abstract] [Full Text] [Figures Only] [PDF]  

Mark S. Blumberg, Adele M. H. Seelke, Steven B. Lowen, and Karl Æ. Karlsson

Dynamics of sleep-wake cyclicity in developing rats
PNAS 2005 102: 14860-14864; published online before print September 28 2005, 10.1073/pnas.0506340102 [Abstract] [Full Text] [Figures Only] [PDF]  

Sergueï O. Fetissov, Jaanus Harro, Maiken Jaanisk, Anu Järv, Iris Podar, Jüri Allik, Ida Nilsson, Priya Sakthivel, Ann Kari Lefvert, and Tomas Hökfelt

Autoantibodies against neuropeptides are associated with psychological traits in eating disorders
PNAS 2005 102: 14865-14870; published online before print September 29 2005, 10.1073/pnas.0507204102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Methods]  

Josef T. Kittler, Guojun Chen, Stephan Honing, Yury Bogdanov, Kristina McAinsh, I. Lorena Arancibia-Carcamo, Jasmina N. Jovanovic, Menelas N. Pangalos, Volker Haucke, Zhen Yan, and Stephen J. Moss

Phospho-dependent binding of the clathrin AP2 adaptor complex to GABA_A receptors regulates the efficacy of inhibitory synaptic transmission
PNAS 2005 102: 14871-14876; published online before print September 28 2005, 10.1073/pnas.0506653102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Chin-Hsing Lin, Stacey Hansen, Zhenshan Wang, Daniel R. Storm, Stephen J. Tapscott, and James M. Olson The dosage of the neuroD2 transcription factor regulates amygdala development and emotional learning PNAS 2005 102: 14877-14882; published online before print October 3 2005, 10.1073/pnas.0506785102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Yi Zhang, Xuenong Bo, Ralf Schoepfer, Anthony J. D. G. Holtmaat, Joost Verhaagen, Piers C. Emson, A. Robert Lieberman, and Patrick N. Anderson

Growth-associated protein GAP-43 and L1 act synergistically to promote regenerative growth of Purkinje cell axons in vivo
PNAS 2005 102: 14883-14888; published online before print September 29 2005, 10.1073/pnas.0505164102 [Abstract] [Full Text] [Figures Only] [PDF]  

Junji Yamauchi, Yuki Miyamoto, Akito Tanoue, Eric M. Shooter, and Jonah R. Chan

Ras activation of a Rac1 exchange factor, Tiam1, mediates neurotrophin-3-induced Schwann cell migration
PNAS 2005 102: 14889-14894; published online before print October 3 2005, 10.1073/pnas.0507125102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Aaron R. Seitz, Noriko Yamagishi, Birgit Werner, Naokazu Goda, Mitsuo Kawato, and Takeo Watanabe

Task-specific disruption of perceptual learning
PNAS 2005 102: 14895-14900; published online before print October 3 2005, 10.1073/pnas.0505765102 [Abstract] [Full Text] [Figures Only] [PDF]  

Spencer LaVere Smith and Thomas Stephen Otis

Pattern-dependent, simultaneous plasticity differentially transforms the input-output relationship of a feedforward circuit
PNAS 2005 102: 14901-14906; published online before print September 30 2005, 10.1073/pnas.0505028102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jin Zhou, Donald W. Pfaff, and Gong Chen

Sex differences in estrogenic regulation of neuronal activity in neonatal cultures of ventromedial nucleus of the hypothalamus
PNAS 2005 102: 14907-14912; published online before print October 4 2005, 10.1073/pnas.0507440102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Physiology

Kyung-Jong Won, Kenton M. Sanders, and Sean M. Ward

Interstitial cells of Cajal mediate mechanosensitive responses in the stomach
PNAS 2005 102: 14913-14918; published online before print October 4 2005, 10.1073/pnas.0503628102 [Abstract] [Full Text] [Figures Only] [PDF]  

Plant Biology

Balazs Siminszky, Lily Gavilano, Steven W. Bowen, and Ralph E. Dewey

Conversion of nicotine to nornicotine in Nicotiana tabacum is mediated by CYP82E4, a cytochrome P450 monooxygenase
PNAS 2005 102: 14919-14924; published online before print September 28 2005, 10.1073/pnas.0506581102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Psychology

John-Dylan Haynes, Jason Tregellas, and Geraint Rees

Attentional integration between anatomically distinct stimulus representations in early visual cortex
PNAS 2005 102: 14925-14930; published online before print September 28 2005, 10.1073/pnas.0501684102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

M. Rosario Rueda, Mary K. Rothbart, Bruce D. McCandliss, Lisa Saccomanno, and Michael I. Posner From The Cover: Training, maturation, and genetic influences on the development of executive attention PNAS 2005 102: 14931-14936; published online before print September 28 2005, 10.1073/pnas.0506897102 [Abstract] [Full Text] [Figures Only] [PDF]   See Commentary on page 14479