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Table of Contents

December 13, 2005; 102 (50)  [Index By Author]  [Cover Photo]  [Masthead (PDF)]

FROM THE COVER

Polyspecific exporter of toxic organic cations

Highly optimized tolerance in wildfire modeling

Mitochondrial DNA role in aging phenotypes

Antinociceptive effects of gabapentin

Population collapse risk from sex ratio bias

IN THIS ISSUE

COMMENTARIES

PHYSICAL SCIENCES
    Chemistry
    Environmental Sciences
    Geophysics
    Sustainability Science

SOCIAL SCIENCES

BIOLOGICAL SCIENCES
    Agricultural Sciences
    Biochemistry
    Biophysics
    Cell Biology
    Developmental Biology
    Ecology
    Evolution
    Genetics

    Immunology
    Medical Sciences
    Microbiology
    Neuroscience
    Physiology
    Plant Biology
    Population Biology
    Psychology

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IN THIS ISSUE

This Week in PNAS
PNAS 2005 102: 17883-17884. [Full Text] [PDF]  

COMMENTARIES

Anthony H. Dickenson, Lucy A. Bee, and Rie Suzuki
Pains, gains, and midbrains
PNAS 2005 102: 17885-17886; published online before print December 5 2005, 10.1073/pnas.0508494102 [Extract] [Full Text] [PDF]  
See companion article on page 18195

Venkatesan Sundaresan
Control of seed size in plants
PNAS 2005 102: 17887-17888; published online before print December 5 2005, 10.1073/pnas.0509021102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 17531 in issue 48 of volume 102

Albert R. La Spada
Huntington's disease and neurogenesis: FGF-2 to the rescue?
PNAS 2005 102: 17889-17890; published online before print December 5 2005, 10.1073/pnas.0509222102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 18189

PHYSICAL SCIENCES

Chemistry

Andrzej L. Sobolewski, Wolfgang Domcke, and C. Hättig
Tautomeric selectivity of the excited-state lifetime of guanine/cytosine base pairs: The role of electron-driven proton-transfer processes
PNAS 2005 102: 17903-17906; published online before print December 5 2005, 10.1073/pnas.0504087102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Data Set]  

E. Charles H. Sykes, Luis C. Fernández-Torres, Sanjini U. Nanayakkara, Brent A. Mantooth, Ryan M. Nevin, and Paul S. Weiss
Observation and manipulation of subsurface hydride in Pd{111} and its effect on surface chemical, physical, and electronic properties
PNAS 2005 102: 17907-17911; published online before print December 1 2005, 10.1073/pnas.0506657102 [Abstract] [Full Text] [Figures Only] [PDF]  

Briar R. Ertz-Berger, Huamei He, Candice Dowell, Stephen M. Factor, Todd E. Haim, Sara Nunez, Steven D. Schwartz, Joanne S. Ingwall, and Jil C. Tardiff
Changes in the chemical and dynamic properties of cardiac troponin T cause discrete cardiomyopathies in transgenic mice
PNAS 2005 102: 18219-18224; published online before print December 2 2005, 10.1073/pnas.0509181102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Environmental Sciences

I. M. Held, T. L. Delworth, J. Lu, K. L. Findell, and T. R. Knutson
Inaugural Article by a Recently Elected Academy Member:
Inaugural Article: Simulation of Sahel drought in the 20th and 21st centuries
PNAS 2005 102: 17891-17896; published online before print December 1 2005, 10.1073/pnas.0509057102 [Abstract] [Full Text] [Figures Only] [PDF]  

Max A. Moritz, Marco E. Morais, Lora A. Summerell, J. M. Carlson, and John Doyle
From the Cover: Wildfires, complexity, and highly optimized tolerance
PNAS 2005 102: 17912-17917; published online before print December 6 2005, 10.1073/pnas.0508985102 [Abstract] [Full Text] [Figures Only] [PDF]  

Geophysics

S. Speziale, A. Milner, V. E. Lee, S. M. Clark, M. P. Pasternak, and R. Jeanloz
Iron spin transition in Earth's mantle
PNAS 2005 102: 17918-17922; published online before print December 5 2005, 10.1073/pnas.0508919102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Sustainability Science

Max A. Moritz, Marco E. Morais, Lora A. Summerell, J. M. Carlson, and John Doyle
From the Cover: Wildfires, complexity, and highly optimized tolerance
PNAS 2005 102: 17912-17917; published online before print December 6 2005, 10.1073/pnas.0508985102 [Abstract] [Full Text] [Figures Only] [PDF]  

SOCIAL SCIENCES

BIOLOGICAL SCIENCES

Agricultural Sciences

David H. Baker
Inaugural Article by a Recently Elected Academy Member:
Inaugural Article: Comparative nutrition and metabolism: Explication of open questions with emphasis on protein and amino acids
PNAS 2005 102: 17897-17902; published online before print December 2 2005, 10.1073/pnas.0509317102 [Abstract] [Full Text] [PDF]  

Biochemistry

Masato Otsuka, Takuya Matsumoto, Riyo Morimoto, Shigeo Arioka, Hiroshi Omote, and Yoshinori Moriyama
From the Cover: A human transporter protein that mediates the final excretion step for toxic organic cations
PNAS 2005 102: 17923-17928; published online before print December 5 2005, 10.1073/pnas.0506483102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Hiromi Imamura, Mizuho Takeda, Saeko Funamoto, Katsuya Shimabukuro, Masasuke Yoshida, and Ken Yokoyama
Rotation scheme of V1-motor is different from that of F1-motor
PNAS 2005 102: 17929-17933; published online before print December 5 2005, 10.1073/pnas.0507764102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Lennart Randau, Kate Calvin, Michelle Hall, Jing Yuan, Mircea Podar, Hong Li, and Dieter Söll
The heteromeric Nanoarchaeum equitans splicing endonuclease cleaves noncanonical bulge–helix–bulge motifs of joined tRNA halves
PNAS 2005 102: 17934-17939; published online before print December 5 2005, 10.1073/pnas.0509197102 [Abstract] [Full Text] [Figures Only] [PDF]  

Noah Dephoure, Russell W. Howson, Justin D. Blethrow, Kevan M. Shokat, and Erin K. O'Shea
Combining chemical genetics and proteomics to identify protein kinase substrates
PNAS 2005 102: 17940-17945; published online before print December 5 2005, 10.1073/pnas.0509080102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Eduard Torrents, Margareta Sahlin, Daniele Biglino, Astrid Gräslund, and Britt-Marie Sjöberg
Efficient growth inhibition of Bacillus anthracis by knocking out the ribonucleotide reductase tyrosyl radical
PNAS 2005 102: 17946-17951; published online before print December 1 2005, 10.1073/pnas.0506410102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Baibaswata Nayak, Ping Xie, Shigeru Akagi, Qiwei Yang, Lin Sun, Jun Wada, Arun Thakur, Farhad R. Danesh, Sumant S. Chugh, and Yashpal S. Kanwar
Modulation of renal-specific oxidoreductase/myo-inositol oxygenase by high-glucose ambience
PNAS 2005 102: 17952-17957; published online before print December 5 2005, 10.1073/pnas.0509089102 [Abstract] [Full Text] [Figures Only] [PDF]  

Biophysics

J. R. Simard, P. A. Zunszain, C.-E. Ha, J. S. Yang, N. V. Bhagavan, I. Petitpas, S. Curry, and J. A. Hamilton
Locating high-affinity fatty acid-binding sites on albumin by x-ray crystallography and NMR spectroscopy
PNAS 2005 102: 17958-17963; published online before print December 5 2005, 10.1073/pnas.0506440102 [Abstract] [Full Text] [Figures Only] [PDF]  

Zhengshuang Shi, Kang Chen, Zhigang Liu, Angela Ng, W. Clay Bracken, and Neville R. Kallenbach
Polyproline II propensities from GGXGG peptides reveal an anticorrelation with {beta}-sheet scales
PNAS 2005 102: 17964-17968; published online before print December 5 2005, 10.1073/pnas.0507124102 [Abstract] [Full Text] [Figures Only] [PDF]  

Gang Lu, James M. Westbrooks, Amy L. Davidson, and Jue Chen
ATP hydrolysis is required to reset the ATP-binding cassette dimer into the resting-state conformation
PNAS 2005 102: 17969-17974; published online before print December 2 2005, 10.1073/pnas.0506039102 [Abstract] [Full Text] [Figures Only] [PDF]  

Cell Biology

Lisa J. Pagliari, Tomomi Kuwana, Christine Bonzon, Donald D. Newmeyer, Shine Tu, Helen M. Beere, and Douglas R. Green
The multidomain proapoptotic molecules Bax and Bak are directly activated by heat
PNAS 2005 102: 17975-17980; published online before print December 5 2005, 10.1073/pnas.0506712102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Tomasz J. Proszynski, Robin W. Klemm, Maike Gravert, Peggy P. Hsu, Yvonne Gloor, Jan Wagner, Karol Kozak, Hannes Grabner, Karen Walzer, Michel Bagnat, Kai Simons, and Christiane Walch-Solimena
A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast
PNAS 2005 102: 17981-17986; published online before print December 5 2005, 10.1073/pnas.0509107102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Cary D. Austin, Xiaohui Wen, Lewis Gazzard, Christopher Nelson, Richard H. Scheller, and Suzie J. Scales
Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody–drug conjugates
PNAS 2005 102: 17987-17992; published online before print December 1 2005, 10.1073/pnas.0509035102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Aleksandra Trifunovic, Anna Hansson, Anna Wredenberg, Anja T. Rovio, Eric Dufour, Ivan Khvorostov, Johannes N. Spelbrink, Rolf Wibom, Howard T. Jacobs, and Nils-Göran Larsson
From the Cover: Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production
PNAS 2005 102: 17993-17998; published online before print December 6 2005, 10.1073/pnas.0508886102 [Abstract] [Full Text] [Figures Only] [PDF]  
See Commentary on page 18769

Takehiro Sato, Masatoshi Esaki, Julio M. Fernandez, and Toshiya Endo
Comparison of the protein-unfolding pathways between mitochondrial protein import and atomic-force microscopy measurements
PNAS 2005 102: 17999-18004; published online before print December 2 2005, 10.1073/pnas.0504495102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ashwini Jambhekar, Kimberly McDermott, Katherine Sorber, Kelly A. Shepard, Ronald D. Vale, Peter A. Takizawa, and Joseph L. DeRisi
Unbiased selection of localization elements reveals cis-acting determinants of mRNA bud localization in Saccharomyces cerevisiae
PNAS 2005 102: 18005-18010; published online before print December 2 2005, 10.1073/pnas.0509229102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Developmental Biology

May-yun Wang, Lelio Orci, Mariella Ravazzola, and Roger H. Unger
Fat storage in adipocytes requires inactivation of leptin's paracrine activity: Implications for treatment of human obesity
PNAS 2005 102: 18011-18016; published online before print December 2 2005, 10.1073/pnas.0509001102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

A. Aziz Aboobaker, Pavel Tomancak, Nipam Patel, Gerald M. Rubin, and Eric C. Lai
Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development
PNAS 2005 102: 18017-18022; published online before print December 5 2005, 10.1073/pnas.0508823102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE  

Tatsuya Kobayashi, Karen M. Lyons, Andrew P. McMahon, and Henry M. Kronenberg
BMP signaling stimulates cellular differentiation at multiple steps during cartilage development
PNAS 2005 102: 18023-18027; published online before print December 1 2005, 10.1073/pnas.0503617102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ekyune Kim, Daichi Baba, Masanori Kimura, Misuzu Yamashita, Shin-ichi Kashiwabara, and Tadashi Baba
Identification of a hyaluronidase, Hyal5, involved in penetration of mouse sperm through cumulus mass
PNAS 2005 102: 18028-18033; published online before print December 5 2005, 10.1073/pnas.0506825102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Masao Murakami, Masayo Nakagawa, Eric N. Olson, and Osamu Nakagawa
A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt–Oram syndrome
PNAS 2005 102: 18034-18039; published online before print December 6 2005, 10.1073/pnas.0509109102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Ecology

Sergey Gavrilets and Aaron Vose
Dynamic patterns of adaptive radiation
PNAS 2005 102: 18040-18045; published online before print December 5 2005, 10.1073/pnas.0506330102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Sergio A. Navarrete, Evie A. Wieters, Bernardo R. Broitman, and Juan Carlos Castilla
Scales of benthic–pelagic coupling and the intensity of species interactions: From recruitment limitation to top-down control
PNAS 2005 102: 18046-18051; published online before print December 6 2005, 10.1073/pnas.0509119102 [Abstract] [Full Text] [Figures Only] [PDF]  

Richard J. Norby, Evan H. DeLucia, Birgit Gielen, Carlo Calfapietra, Christian P. Giardina, John S. King, Joanne Ledford, Heather R. McCarthy, David J. P. Moore, Reinhart Ceulemans, Paolo De Angelis, Adrien C. Finzi, David F. Karnosky, Mark E. Kubiske, Martin Lukac, Kurt S. Pregitzer, Giuseppe E. Scarascia-Mugnozza, William H. Schlesinger, and Ram Oren
Forest response to elevated CO2 is conserved across a broad range of productivity
PNAS 2005 102: 18052-18056; published online before print December 5 2005, 10.1073/pnas.0509478102 [Abstract] [Full Text] [Figures Only] [PDF]  

Evolution

David C. Lahti
Evolution of bird eggs in the absence of cuckoo parasitism
PNAS 2005 102: 18057-18062; published online before print December 2 2005, 10.1073/pnas.0508930102 [Abstract] [Full Text] [Figures Only] [PDF]  

Kazuhiko Kawasaki, Tohru Suzuki, and Kenneth M. Weiss
Phenogenetic drift in evolution: The changing genetic basis of vertebrate teeth
PNAS 2005 102: 18063-18068; published online before print December 6 2005, 10.1073/pnas.0509263102 [Abstract] [Full Text] [Figures Only] [PDF]  

Genetics

Eliane El Achkar, Michelle Gerbault-Seureau, Martine Muleris, Bernard Dutrillaux, and Michelle Debatisse
Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites
PNAS 2005 102: 18069-18074; published online before print December 5 2005, 10.1073/pnas.0506497102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Suk-Hee Lee, Masahiko Oshige, Stephen T. Durant, Kanwaldeep Kaur Rasila, Elizabeth A. Williamson, Heather Ramsey, Lori Kwan, Jac A. Nickoloff, and Robert Hromas
The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair
PNAS 2005 102: 18075-18080; published online before print December 6 2005, 10.1073/pnas.0503676102 [Abstract] [Full Text] [Figures Only] [PDF]  

Nadia Felli, Laura Fontana, Elvira Pelosi, Rosanna Botta, Desirée Bonci, Francesco Facchiano, Francesca Liuzzi, Valentina Lulli, Ornella Morsilli, Simona Santoro, Mauro Valtieri, George Adrian Calin, Chang-Gong Liu, Antonio Sorrentino, Carlo M. Croce, and Cesare Peschle
MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation
PNAS 2005 102: 18081-18086; published online before print December 5 2005, 10.1073/pnas.0506216102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Lyubov A. Lebedeva, Elena N. Nabirochkina, Mariya M. Kurshakova, Flavie Robert, Aleksey N. Krasnov, Mihail B. Evgen'ev, James T. Kadonaga, Sofia G. Georgieva, and Làszlò Tora
Occupancy of the Drosophila hsp70 promoter by a subset of basal transcription factors diminishes upon transcriptional activation
PNAS 2005 102: 18087-18092; published online before print December 5 2005, 10.1073/pnas.0509063102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Immunology

Tatyana A. Souza, B. David Stollar, John L. Sullivan, Katherine Luzuriaga, and David A. Thorley-Lawson
Peripheral B cells latently infected with Epstein–Barr virus display molecular hallmarks of classical antigen-selected memory B cells
PNAS 2005 102: 18093-18098; published online before print December 5 2005, 10.1073/pnas.0509311102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE  

Lauren Clancy, Karen Mruk, Kristina Archer, Melissa Woelfel, Juthathip Mongkolsapaya, Gavin Screaton, Michael J. Lenardo, and Francis Ka-Ming Chan
Preligand assembly domain-mediated ligand-independent association between TRAIL receptor 4 (TR4) and TR2 regulates TRAIL-induced apoptosis
PNAS 2005 102: 18099-18104; published online before print November 30 2005, 10.1073/pnas.0507329102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Yojiro Arinobu, Hiromi Iwasaki, Michael F. Gurish, Shin-ichi Mizuno, Hirokazu Shigematsu, Hidetoshi Ozawa, Daniel G. Tenen, K. Frank Austen, and Koichi Akashi
Developmental checkpoints of the basophil/mast cell lineages in adult murine hematopoiesis
PNAS 2005 102: 18105-18110; published online before print December 5 2005, 10.1073/pnas.0509148102 [Abstract] [Full Text] [Figures Only] [PDF]  

Medical Sciences

Herbert Spring, Thomas Schüler, Bernd Arnold, Günter J. Hämmerling, and Ruth Ganss
Chemokines direct endothelial progenitors into tumor neovessels
PNAS 2005 102: 18111-18116; published online before print December 2 2005, 10.1073/pnas.0507158102 [Abstract] [Full Text] [Figures Only] [PDF]  

Se-Jin Lee, Lori A. Reed, Monique V. Davies, Stefan Girgenrath, Mary E. P. Goad, Kathy N. Tomkinson, Jill F. Wright, Christopher Barker, Gregory Ehrmantraut, James Holmstrom, Betty Trowell, Barry Gertz, Man-Shiow Jiang, Suzanne M. Sebald, Martin Matzuk, En Li, Li-fang Liang, Edwin Quattlebaum, Ronald L. Stotish, and Neil M. Wolfman
Regulation of muscle growth by multiple ligands signaling through activin type II receptors
PNAS 2005 102: 18117-18122; published online before print December 5 2005, 10.1073/pnas.0505996102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE  

Cordula M. Wolf, Ivan P. G. Moskowitz, Scott Arno, Dorothy M. Branco, Christopher Semsarian, Scott A. Bernstein, Michael Peterson, Michael Maida, Gregory E. Morley, Glenn Fishman, Charles I. Berul, Christine E. Seidman, and J. G. Seidman
Somatic events modify hypertrophic cardiomyopathy pathology and link hypertrophy to arrhythmia
PNAS 2005 102: 18123-18128; published online before print December 6 2005, 10.1073/pnas.0509145102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE  

Jan Wehkamp, Nita H. Salzman, Edith Porter, Sabine Nuding, Michael Weichenthal, Robert E. Petras, Bo Shen, Elke Schaeffeler, Matthias Schwab, Rose Linzmeier, Ryan W. Feathers, Hiutung Chu, Heriberto Lima, Jr., Klaus Fellermann, Tomas Ganz, Eduard F. Stange, and Charles L. Bevins
Reduced Paneth cell {alpha}-defensins in ileal Crohn's disease
PNAS 2005 102: 18129-18134; published online before print December 5 2005, 10.1073/pnas.0505256102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Feng Xu, Judianne Davis, Jianting Miao, Mary Lou Previti, Galina Romanov, Kelly Ziegler, and William E. Van Nostrand
Protease nexin-2/amyloid {beta}-protein precursor limits cerebral thrombosis
PNAS 2005 102: 18135-18140; published online before print December 5 2005, 10.1073/pnas.0507798102 [Abstract] [Full Text] [Figures Only] [PDF]  

Microbiology

J. A. van der Goot, G. Koch, M. C. M. de Jong, and M. van Boven
Quantification of the effect of vaccination on transmission of avian influenza (H7N7) in chickens
PNAS 2005 102: 18141-18146; published online before print December 5 2005, 10.1073/pnas.0505098102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

E. F. Mongodin, K. E. Nelson, S. Daugherty, R. T. DeBoy, J. Wister, H. Khouri, J. Weidman, D. A. Walsh, R. T. Papke, G. Sanchez Perez, A. K. Sharma, C. L. Nesbø, D. MacLeod, E. Bapteste, W. F. Doolittle, R. L. Charlebois, B. Legault, and F. Rodriguez-Valera
The genome of Salinibacter ruber: Convergence and gene exchange among hyperhalophilic bacteria and archaea
PNAS 2005 102: 18147-18152; published online before print December 5 2005, 10.1073/pnas.0509073102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Dai Wang and Thomas Shenk
Human cytomegalovirus virion protein complex required for epithelial and endothelial cell tropism
PNAS 2005 102: 18153-18158; published online before print November 30 2005, 10.1073/pnas.0509201102 [Abstract] [Full Text] [Figures Only] [PDF]  

Tsubasa Munakata, Mitsuyasu Nakamura, Yuqiong Liang, Kui Li, and Stanley M. Lemon
Down-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymerase
PNAS 2005 102: 18159-18164; published online before print December 6 2005, 10.1073/pnas.0505605102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Neuroscience

Jonghan Shin, Daesoo Kim, Riccardo Bianchi, Robert K. S. Wong, and Hee-Sup Shin
Genetic dissection of theta rhythm heterogeneity in mice
PNAS 2005 102: 18165-18170; published online before print December 5 2005, 10.1073/pnas.0505498102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

James R. Munoz, Brooke R. Stoutenger, Andrew P. Robinson, Jeffrey L. Spees, and Darwin J. Prockop
Human stem/progenitor cells from bone marrow promote neurogenesis of endogenous neural stem cells in the hippocampus of mice
PNAS 2005 102: 18171-18176; published online before print December 5 2005, 10.1073/pnas.0508945102 [Abstract] [Full Text] [Figures Only] [PDF]  

Massimo Mantegazza, Antonio Gambardella, Raffaella Rusconi, Emanuele Schiavon, Ferdinanda Annesi, Rita Restano Cassulini, Angelo Labate, Sara Carrideo, Rosanna Chifari, Maria Paola Canevini, Raffaele Canger, Silvana Franceschetti, Grazia Annesi, Enzo Wanke, and Aldo Quattrone
Identification of an Nav1.1 sodium channel (SCN1A) loss-of-function mutation associated with familial simple febrile seizures
PNAS 2005 102: 18177-18182; published online before print December 2 2005, 10.1073/pnas.0506818102 [Abstract] [Full Text] [Figures Only] [PDF]  

Annalisa Buffo, Milan R. Vosko, Dilek Ertürk, Gerhard F. Hamann, Mathias Jucker, David Rowitch, and Magdalena Götz
Expression pattern of the transcription factor Olig2 in response to brain injuries: Implications for neuronal repair
PNAS 2005 102: 18183-18188; published online before print December 5 2005, 10.1073/pnas.0506535102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Kunlin Jin, Michelle LaFevre-Bernt, Yunjuan Sun, Sylvia Chen, Juliette Gafni, Danielle Crippen, Anna Logvinova, Christopher A. Ross, David A. Greenberg, and Lisa M. Ellerby
FGF-2 promotes neurogenesis and neuroprotection and prolongs survival in a transgenic mouse model of Huntington's disease
PNAS 2005 102: 18189-18194; published online before print December 2 2005, 10.1073/pnas.0506375102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  
See Commentary on page 17889

G. D. Iannetti, L. Zambreanu, R. G. Wise, T. J. Buchanan, J. P. Huggins, T. S. Smart, W. Vennart, and I. Tracey
From The Cover: Pharmacological modulation of pain-related brain activity during normal and central sensitization states in humans
PNAS 2005 102: 18195-18200; published online before print December 5 2005, 10.1073/pnas.0506624102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  
See Commentary on page 17885

Robert Pawlak, B. S. Shankaranarayana Rao, Jerry P. Melchor, Sumantra Chattarji, Bruce McEwen, and Sidney Strickland
Tissue plasminogen activator and plasminogen mediate stress-induced decline of neuronal and cognitive functions in the mouse hippocampus
PNAS 2005 102: 18201-18206; published online before print December 5 2005, 10.1073/pnas.0509232102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Thomas Grutter, Lia Prado de Carvalho, Virginie Dufresne, Antoine Taly, Stuart J. Edelstein, and Jean-Pierre Changeux
Molecular tuning of fast gating in pentameric ligand-gated ion channels
PNAS 2005 102: 18207-18212; published online before print November 30 2005, 10.1073/pnas.0509024102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Physiology

Douglas L. Altshuler, William B. Dickson, Jason T. Vance, Stephen P. Roberts, and Michael H. Dickinson
Short-amplitude high-frequency wing strokes determine the aerodynamics of honeybee flight
PNAS 2005 102: 18213-18218; published online before print December 5 2005, 10.1073/pnas.0506590102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Briar R. Ertz-Berger, Huamei He, Candice Dowell, Stephen M. Factor, Todd E. Haim, Sara Nunez, Steven D. Schwartz, Joanne S. Ingwall, and Jil C. Tardiff
Changes in the chemical and dynamic properties of cardiac troponin T cause discrete cardiomyopathies in transgenic mice
PNAS 2005 102: 18219-18224; published online before print December 2 2005, 10.1073/pnas.0509181102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE  

Plant Biology

Bobby A. Brown, Catherine Cloix, Guang Huai Jiang, Eirini Kaiserli, Pawel Herzyk, Daniel J. Kliebenstein, and Gareth I. Jenkins
A UV-B-specific signaling component orchestrates plant UV protection
PNAS 2005 102: 18225-18230; published online before print December 5 2005, 10.1073/pnas.0507187102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Population Biology

Jean-François Le Galliard, Patrick S. Fitze, Régis Ferrière, and Jean Clobert
From The Cover: Sex ratio bias, male aggression, and population collapse in lizards
PNAS 2005 102: 18231-18236; published online before print December 1 2005, 10.1073/pnas.0505172102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Psychology

Daniel A. Cohen, Alvaro Pascual-Leone, Daniel Z. Press, and Edwin M. Robertson
Off-line learning of motor skill memory: A double dissociation of goal and movement
PNAS 2005 102: 18237-18241; published online before print December 5 2005, 10.1073/pnas.0506072102 [Abstract] [Full Text] [Figures Only] [PDF]  

CORRECTIONS

Correction for Ortiz-García et al., Absence of detectable transgenes in local landraces of maize in Oaxaca, Mexico (2003–2004), PNAS 2005 102:12338-12343 [Extract] [Full Text] [PDF]  

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