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IN THIS ISSUE

This Week in PNAS
PNAS 2005 102: 1809-1810. [Full Text] [Figures Only] [PDF]  

COMMENTARIES

Stephen B. Shears

Telomere maintenance by intracellular signals: New kid on the block?
PNAS 2005 102: 1811-1812; published online before print January 31 2005, 10.1073/pnas.0409801102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 1911

Arieh Warshel

Inverting the selectivity of aquaporin 6: Gating versus direct electrostatic interaction
PNAS 2005 102: 1813-1814; published online before print January 31 2005, 10.1073/pnas.0409788102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 2192

Kanwarpal S. Dhugga

Plant Golgi cell wall synthesis: From genes to enzyme activities
PNAS 2005 102: 1815-1816; published online before print January 31 2005, 10.1073/pnas.0409649102 [Extract] [Full Text] [PDF]  
See companion article on page 2221

Shoko Ueki and Vitaly Citovsky

Control improves with age: Intercellular transport in plant embryos and adults
PNAS 2005 102: 1817-1818; published online before print January 31 2005, 10.1073/pnas.0409785102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 2227

PHYSICAL SCIENCES

Applied Mathematics

Médéric Argentina and L. Mahadevan

Fluid-flow-induced flutter of a flag
PNAS 2005 102: 1829-1834; published online before print January 31 2005, 10.1073/pnas.0408383102 [Abstract] [Full Text] [Figures Only] [PDF]  

Chemistry

V. Barsegov and D. Thirumalai

Dynamics of unbinding of cell adhesion molecules: Transition from catch to slip bonds
PNAS 2005 102: 1835-1839. [Abstract] [Full Text] [Figures Only] [PDF]  

Carlos A. Meriles, Dimitris Sakellariou, Andreas H. Trabesinger, Vasiliki Demas, and Alexander Pines

Zero- to low-field MRI with averaging of concomitant gradient fields
PNAS 2005 102: 1840-1842; published online before print January 25 2005, 10.1073/pnas.0409115102 [Abstract] [Full Text] [Figures Only] [PDF]  

R. Dean Astumian

Chemical peristalsis
PNAS 2005 102: 1843-1847; published online before print January 26 2005, 10.1073/pnas.0409341102 [Abstract] [Full Text] [Figures Only] [PDF]  

Ralf Seemann, Martin Brinkmann, Edward J. Kramer, Frederick F. Lange, and Reinhard Lipowsky Wetting morphologies at microstructured surfaces PNAS 2005 102: 1848-1852; published online before print January 27 2005, 10.1073/pnas.0407721102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Graham E. Ball, Tamim A. Darwish, Spili Geftakis, Michael W. George, Douglas J. Lawes, Peter Portius, and Jonathan P. Rourke

Characterization of an organometallic xenon complex using NMR and IR spectroscopy
PNAS 2005 102: 1853-1858; published online before print January 27 2005, 10.1073/pnas.0406527102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Geology

Edward Irving Inaugural Article by a Recently Elected Academy Member: Inaugural Article: The role of latitude in mobilism debates PNAS 2005 102: 1821-1828; published online before print January 31 2005, 10.1073/pnas.0408162101 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]

SOCIAL SCIENCES

Anthropology

E. A. Hammel

Demographic dynamics and kinship in anthropological populations
PNAS 2005 102: 2248-2253; published online before print January 27 2005, 10.1073/pnas.0409762102 [Abstract] [Full Text] [Figures Only] [PDF]  

Economic Sciences

J. Doyne Farmer, Paolo Patelli, and Ilija I. Zovko

The predictive power of zero intelligence in financial markets
PNAS 2005 102: 2254-2259; published online before print February 1 2005, 10.1073/pnas.0409157102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

BIOLOGICAL SCIENCES

Biochemistry

Andrei Kuzmichev, Raphael Margueron, Alejandro Vaquero, Tanja S. Preissner, Michael Scher, Antonis Kirmizis, Xuesong Ouyang, Neil Brockdorff, Cory Abate-Shen, Peggy Farnham, and Danny Reinberg

Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation
PNAS 2005 102: 1859-1864; published online before print January 31 2005, 10.1073/pnas.0409875102 [Abstract] [Full Text] [Figures Only] [PDF]  

John Dresios, Armaz Aschrafi, Geoffrey C. Owens, Peter W. Vanderklish, Gerald M. Edelman, and Vincent P. Mauro

Cold stress-induced protein Rbm3 binds 60S ribosomal subunits, alters microRNA levels, and enhances global protein synthesis
PNAS 2005 102: 1865-1870; published online before print January 31 2005, 10.1073/pnas.0409764102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

George Kontopidis, Su-Ying Wu, Daniella I. Zheleva, Paul Taylor, Campbell McInnes, David P. Lane, Peter M. Fischer, and Malcolm D. Walkinshaw From the Cover: Structural and biochemical studies of human proliferating cell nuclear antigen complexes provide a rationale for cyclin association and inhibitor design PNAS 2005 102: 1871-1876; published online before print January 28 2005, 10.1073/pnas.0406540102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]

Boris Kysela, Miroslav Chovanec, and Penny A. Jeggo

Phosphorylation of linker histones by DNA-dependent protein kinase is required for DNA ligase IV-dependent ligation in the presence of histone H1
PNAS 2005 102: 1877-1882; published online before print January 25 2005, 10.1073/pnas.0401179102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Sinisa Urban and Michael S. Wolfe

Reconstitution of intramembrane proteolysis in vitro reveals that pure rhomboid is sufficient for catalysis and specificity
PNAS 2005 102: 1883-1888; published online before print January 31 2005, 10.1073/pnas.0408306102 [Abstract] [Full Text] [Figures Only] [PDF]  

Biophysics

Sherry L. LaPorte, Charles M. Forsyth, Brian C. Cunningham, Larry J. Miercke, David Akhavan, and Robert M. Stroud

De novo design of an IL-4 antagonist and its structure at 1.9 Å
PNAS 2005 102: 1889-1894; published online before print January 31 2005, 10.1073/pnas.0408890102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

José Manuel González, Marisela Vélez, Mercedes Jiménez, Carlos Alfonso, Peter Schuck, Jesús Mingorance, Miguel Vicente, Allen P. Minton, and Germán Rivas

Cooperative behavior of Escherichia coli cell-division protein FtsZ assembly involves the preferential cyclization of long single-stranded fibrils
PNAS 2005 102: 1895-1900; published online before print January 31 2005, 10.1073/pnas.0409517102 [Abstract] [Full Text] [Figures Only] [PDF]  

Rebecca Page, Wolfgang Peti, Ian A. Wilson, Raymond C. Stevens, and Kurt Wüthrich

NMR screening and crystal quality of bacterially expressed prokaryotic and eukaryotic proteins in a structural genomics pipeline
PNAS 2005 102: 1901-1905; published online before print January 27 2005, 10.1073/pnas.0408490102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Cell Biology

Pauline Lee, Hongfan Peng, Terri Gelbart, Lei Wang, and Ernest Beutler

Regulation of hepcidin transcription by interleukin-1 and interleukin-6
PNAS 2005 102: 1906-1910; published online before print January 31 2005, 10.1073/pnas.0409808102 [Abstract] [Full Text] [Figures Only] [PDF]  

Adolfo Saiardi, Adam C. Resnick, Adele M. Snowman, Beverly Wendland, and Solomon H. Snyder From the Cover: Inositol pyrophosphates regulate cell death and telomere length through phosphoinositide 3-kinase-related protein kinases PNAS 2005 102: 1911-1914; published online before print January 21 2005, 10.1073/pnas.0409322102 [Abstract] [Full Text] [Figures Only] [PDF]   See Commentary on page 1811

Lilach M. Friedman, Ariel Rinon, Bilha Schechter, Ljuba Lyass, Sara Lavi, Sarah S. Bacus, Michael Sela, and Yosef Yarden

Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: Implications for cancer immunotherapy
PNAS 2005 102: 1915-1920; published online before print January 31 2005, 10.1073/pnas.0409610102 [Abstract] [Full Text] [Figures Only] [PDF]  

Laura Larson, Serge Arnaudeau, Bruce Gibson, Wei Li, Ryoko Krause, Binghua Hao, James R. Bamburg, Daniel P. Lew, Nicolas Demaurex, and Frederick Southwick

Gelsolin mediates calcium-dependent disassembly of Listeria actin tails
PNAS 2005 102: 1921-1926; published online before print January 25 2005, 10.1073/pnas.0409062102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Movies]  

Jun Liu, Anne G. Bang, Chris Kintner, Anthony P. Orth, Sumit K. Chanda, Sheng Ding, and Peter G. Schultz

Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis
PNAS 2005 102: 1927-1932; published online before print January 26 2005, 10.1073/pnas.0409472102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Andre Levchenko, Bipin M. Mehta, Xinle Niu, Grace Kang, Liliana Villafania, Denise Way, Dolores Polycarpe, Michel Sadelain, and Steven M. Larson Intercellular transfer of P-glycoprotein mediates acquired multidrug resistance in tumor cells PNAS 2005 102: 1933-1938; published online before print January 25 2005, 10.1073/pnas.0401851102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Ryoko Nishiuchi, Noriko Sanzen, Shigeyuki Nada, Yasuhiro Sumida, Yoshinao Wada, Masato Okada, Junichi Takagi, Hitoshi Hasegawa, and Kiyotoshi Sekiguchi

Potentiation of the ligand-binding activity of integrin 31 via association with tetraspanin CD151
PNAS 2005 102: 1939-1944; published online before print January 26 2005, 10.1073/pnas.0409493102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Alessandro Vichi, D. Michael Payne, Gustavo Pacheco-Rodriguez, Joel Moss, and Martha Vaughan

E3 ubiquitin ligase activity of the trifunctional ARD1 (ADP-ribosylation factor domain protein 1)
PNAS 2005 102: 1945-1950; published online before print January 31 2005, 10.1073/pnas.0409800102 [Abstract] [Full Text] [Figures Only] [PDF]  

Developmental Biology

Jasmin Fisher, Nir Piterman, E. Jane Albert Hubbard, Michael J. Stern, and David Harel

Computational insights into Caenorhabditis elegans vulval development
PNAS 2005 102: 1951-1956; published online before print January 31 2005, 10.1073/pnas.0409433102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ray K. Ng and John B. Gurdon

Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer
PNAS 2005 102: 1957-1962; published online before print January 31 2005, 10.1073/pnas.0409813102 [Abstract] [Full Text] [Figures Only] [PDF]  

Ecology

Janne S. Kotiaho, Veijo Kaitala, Atte Komonen, and Jussi Päivinen

Predicting the risk of extinction from shared ecological characteristics
PNAS 2005 102: 1963-1967; published online before print January 25 2005, 10.1073/pnas.0406718102 [Abstract] [Full Text] [Figures Only] [PDF]  

Evolution

Christophe Fraser, William P. Hanage, and Brian G. Spratt

Neutral microepidemic evolution of bacterial pathogens
PNAS 2005 102: 1968-1973; published online before print January 31 2005, 10.1073/pnas.0406993102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Roded Sharan, Silpa Suthram, Ryan M. Kelley, Tanja Kuhn, Scott McCuine, Peter Uetz, Taylor Sittler, Richard M. Karp, and Trey Ideker From the Cover: Conserved patterns of protein interaction in multiple species PNAS 2005 102: 1974-1979; published online before print February 1 2005, 10.1073/pnas.0409522102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] [Online Correction to Supporting Methods]

Ananias A. Escalante, Omar E. Cornejo, Denise E. Freeland, Amanda C. Poe, Ester Durrego, William E. Collins, and Altaf A. Lal

A monkey's tale: The origin of Plasmodium vivax as a human malaria parasite
PNAS 2005 102: 1980-1985; published online before print January 31 2005, 10.1073/pnas.0409652102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Scott W. Roy and Walter Gilbert

Complex early genes
PNAS 2005 102: 1986-1991; published online before print February 1 2005, 10.1073/pnas.0408355101 [Abstract] [Full Text] [Figures Only] [PDF]  

Genetics

Wei Wang, J. Michael Cherry, Yigal Nochomovitz, Emmitt Jolly, David Botstein, and Hao Li

Inference of combinatorial regulation in yeast transcriptional networks: A case study of sporulation
PNAS 2005 102: 1998-2003; published online before print January 31 2005, 10.1073/pnas.0405537102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Stefan Kammerer, Richard B. Roth, Carolyn R. Hoyal, Richard Reneland, George Marnellos, Marion Kiechle, Ulrike Schwarz-Boeger, Lyn R. Griffiths, Florian Ebner, Joachim Rehbock, Charles R. Cantor, Matthew R. Nelson, and Andreas Braun

Association of the NuMA region on chromosome 11q13 with breast cancer susceptibility
PNAS 2005 102: 2004-2009; published online before print January 31 2005, 10.1073/pnas.0409806102 [Abstract] [Full Text] [Figures Only] [PDF]  

Immunology

Devangi S. Mehta, Andrea L. Wurster, Amy S. Weinmann, and Michael J. Grusby

NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression
PNAS 2005 102: 2016-2021; published online before print January 31 2005, 10.1073/pnas.0409512102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Hitoshi Nagaoka, Satomi Ito, Masamichi Muramatsu, Mikiyo Nakata, and Tasuku Honjo

DNA cleavage in immunoglobulin somatic hypermutation depends on de novo protein synthesis but not on uracil DNA glycosylase
PNAS 2005 102: 2022-2027; published online before print January 31 2005, 10.1073/pnas.0409491102 [Abstract] [Full Text] [Figures Only] [PDF]  

Hava Ben-David, Michael Sela, and Edna Mozes

Down-regulation of myasthenogenic T cell responses by a dual altered peptide ligand via CD4⁺CD25⁺-regulated events leading to apoptosis
PNAS 2005 102: 2028-2033; published online before print January 26 2005, 10.1073/pnas.0409549102 [Abstract] [Full Text] [Figures Only] [PDF]  

Yingkai Tong, Thomas Aune, and Mark Boothby

T-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN- promoter via a conserved T-box half-site
PNAS 2005 102: 2034-2039; published online before print January 31 2005, 10.1073/pnas.0409510102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Medical Sciences

Maria E. Åkerman, Jan Pilch, David Peters, and Erkki Ruoslahti

Angiostatic peptides use plasma fibronectin to home to angiogenic vasculature
PNAS 2005 102: 2040-2045; published online before print February 1 2005, 10.1073/pnas.0409844102 [Abstract] [Full Text] [Figures Only] [PDF]  

Fabio Fiordaliso, Stefano Chimenti, Lidia Staszewsky, Antonio Bai, Eleonora Carlo, Ivan Cuccovillo, Mirko Doni, Manuela Mengozzi, Rossella Tonelli, Pietro Ghezzi, Thomas Coleman, Michael Brines, Anthony Cerami, and Roberto Latini

A nonerythropoietic derivative of erythropoietin protects the myocardium from ischemia–reperfusion injury
PNAS 2005 102: 2046-2051; published online before print January 25 2005, 10.1073/pnas.0409329102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Rickard Sandberg and Ingemar Ernberg

Assessment of tumor characteristic gene expression in cell lines using a tissue similarity index (TSI)
PNAS 2005 102: 2052-2057; published online before print January 25 2005, 10.1073/pnas.0408105102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Kristina Schoonjans, Laurent Dubuquoy, Joseph Mebis, Elisabeth Fayard, Olivia Wendling, Céline Haby, Karel Geboes, and Johan Auwerx

Liver receptor homolog 1 contributes to intestinal tumor formation through effects on cell cycle and inflammation
PNAS 2005 102: 2058-2062; published online before print January 31 2005, 10.1073/pnas.0409756102 [Abstract] [Full Text] [Figures Only] [PDF]  

Catherine A. M. Stedman, Christopher Liddle, Sally A. Coulter, Junichiro Sonoda, Jacqueline G. A. Alvarez, David D. Moore, Ronald M. Evans, and Michael Downes

Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury
PNAS 2005 102: 2063-2068; published online before print January 31 2005, 10.1073/pnas.0409794102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Kara N. Maxwell, Edward A. Fisher, and Jan L. Breslow Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment PNAS 2005 102: 2069-2074; published online before print January 27 2005, 10.1073/pnas.0409736102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure] OPEN ACCESS ARTICLE

Francesca Chamian, Michelle A. Lowes, Shao-Lee Lin, Edmund Lee, Toyoko Kikuchi, Patricia Gilleaudeau, Mary Sullivan-Whalen, Irma Cardinale, Artemis Khatcherian, Inna Novitskaya, Knut M. Wittkowski, and James G. Krueger Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris PNAS 2005 102: 2075-2080; published online before print January 25 2005, 10.1073/pnas.0409569102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Microbiology

Maria C. Silva, Jörg Schröer, and Thomas Shenk

Human cytomegalovirus cell-to-cell spread in the absence of an essential assembly protein
PNAS 2005 102: 2081-2086; published online before print January 31 2005, 10.1073/pnas.0409597102 [Abstract] [Full Text] [Figures Only] [PDF]  

Stephen T. Chisholm, Douglas Dahlbeck, Nandini Krishnamurthy, Brad Day, Kimmen Sjolander, and Brian J. Staskawicz Molecular characterization of proteolytic cleavage sites of the Pseudomonas syringae effector AvrRpt2 PNAS 2005 102: 2087-2092; published online before print January 31 2005, 10.1073/pnas.0409468102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table] OPEN ACCESS ARTICLE

Galina N. Nikolenko, Sarah Palmer, Frank Maldarelli, John W. Mellors, John M. Coffin, and Vinay K. Pathak

Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: Balance between RNase H activity and nucleotide excision
PNAS 2005 102: 2093-2098; published online before print January 31 2005, 10.1073/pnas.0409823102 [Abstract] [Full Text] [Figures Only] [PDF]  

Eugene Kolker, Alex F. Picone, Michael Y. Galperin, Margaret F. Romine, Roger Higdon, Kira S. Makarova, Natali Kolker, Gordon A. Anderson, Xiaoyun Qiu, Kenneth J. Auberry, Gyorgy Babnigg, Alex S. Beliaev, Paul Edlefsen, Dwayne A. Elias, Yuri A. Gorby, Ted Holzman, Joel A. Klappenbach, Konstantinos T. Konstantinidis, Miriam L. Land, Mary S. Lipton, Lee-Ann McCue, Matthew Monroe, Ljiljana Pasa-Tolic, Grigoriy Pinchuk, Samuel Purvine, Margrethe H. Serres, Sasha Tsapin, Brian A. Zakrajsek, Wenhong Zhu, Jizhong Zhou, Frank W. Larimer, Charles E. Lawrence, Monica Riley, Frank R. Collart, John R. Yates, III, Richard D. Smith, Carol S. Giometti, Kenneth H. Nealson, James K. Fredrickson, and James M. Tiedje Global profiling of Shewanella oneidensis MR-1: Expression of hypothetical genes and improved functional annotations PNAS 2005 102: 2099-2104; published online before print January 31 2005, 10.1073/pnas.0409111102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Neuroscience

Paul M. Kim, Hiroyuki Aizawa, Peter S. Kim, Alex S. Huang, Sasrutha R. Wickramasinghe, Amir H. Kashani, Roxanne K. Barrow, Richard L. Huganir, Anirvan Ghosh, and Solomon H. Snyder

Serine racemase: Activation by glutamate neurotransmission via glutamate receptor interacting protein and mediation of neuronal migration
PNAS 2005 102: 2105-2110; published online before print January 31 2005, 10.1073/pnas.0409723102 [Abstract] [Full Text] [Figures Only] [PDF]  

Jeffrey L. Krichmar, Douglas A. Nitz, Joseph A. Gally, and Gerald M. Edelman Characterizing functional hippocampal pathways in a brain-based device as it solves a spatial memory task PNAS 2005 102: 2111-2116; published online before print January 31 2005, 10.1073/pnas.0409792102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Anh Hai Tran, Ryoi Tamura, Teruko Uwano, Tsuneyuki Kobayashi, Motoya Katsuki, and Taketoshi Ono

Dopamine D1 receptors involved in locomotor activity and accumbens neural responses to prediction of reward associated with place
PNAS 2005 102: 2117-2122; published online before print January 31 2005, 10.1073/pnas.0409726102 [Abstract] [Full Text] [Figures Only] [PDF]  

Verity A. Letts, Connie L. Mahaffey, Barbara Beyer, and Wayne N. Frankel

A targeted mutation in Cacng4 exacerbates spike-wave seizures in stargazer (Cacng2) mice
PNAS 2005 102: 2123-2128; published online before print January 26 2005, 10.1073/pnas.0409527102 [Abstract] [Full Text] [Figures Only] [PDF]  

Muhammad Shahab, Claudio Mastronardi, Stephanie B. Seminara, William F. Crowley, Sergio R. Ojeda, and Tony M. Plant

Increased hypothalamic GPR54 signaling: A potential mechanism for initiation of puberty in primates
PNAS 2005 102: 2129-2134; published online before print January 31 2005, 10.1073/pnas.0409822102 [Abstract] [Full Text] [Figures Only] [PDF]  

Graziano Pinna, Erminio Costa, and Alessandro Guidotti

Changes in brain testosterone and allopregnanolone biosynthesis elicit aggressive behavior
PNAS 2005 102: 2135-2140; published online before print January 27 2005, 10.1073/pnas.0409643102 [Abstract] [Full Text] [Figures Only] [PDF]  

Tieqiao Wen, Clayton A. Parrish, Dan Xu, Qi Wu, and Ping Shen

Drosophila neuropeptide F and its receptor, NPFR1, define a signaling pathway that acutely modulates alcohol sensitivity
PNAS 2005 102: 2141-2146; published online before print January 27 2005, 10.1073/pnas.0406814102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Tuukka T. Raij, Jussi Numminen, Sakari Närvänen, Jaana Hiltunen, and Riitta Hari Brain correlates of subjective reality of physically and psychologically induced pain PNAS 2005 102: 2147-2151; published online before print January 31 2005, 10.1073/pnas.0409542102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Marin Veldic, Alessandro Guidotti, Ekrem Maloku, John M. Davis, and Erminio Costa

In psychosis, cortical interneurons overexpress DNA-methyltransferase 1
PNAS 2005 102: 2152-2157; published online before print January 31 2005, 10.1073/pnas.0409665102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Janita Turchi, Richard C. Saunders, and Mortimer Mishkin

Effects of cholinergic deafferentation of the rhinal cortex on visual recognition memory in monkeys
PNAS 2005 102: 2158-2161; published online before print January 31 2005, 10.1073/pnas.0409708102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Wenxue Li, Neva West, Emanuela Colla, Olga Pletnikova, Juan C. Troncoso, Laura Marsh, Ted M. Dawson, Pekka Jäkälä, Tobias Hartmann, Donald L. Price, and Michael K. Lee

Aggregation promoting C-terminal truncation of -synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations
PNAS 2005 102: 2162-2167; published online before print January 31 2005, 10.1073/pnas.0406976102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Giuseppe Legname, Hoang-Oanh B. Nguyen, Ilia V. Baskakov, Fred E. Cohen, Stephen J. DeArmond, and Stanley B. Prusiner

Strain-specified characteristics of mouse synthetic prions
PNAS 2005 102: 2168-2173; published online before print January 25 2005, 10.1073/pnas.0409079102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table] [Online Correction to Supporting Table 1]  

Francisco A. Perez and Richard D. Palmiter Parkin-deficient mice are not a robust model of parkinsonism PNAS 2005 102: 2174-2179; published online before print January 31 2005, 10.1073/pnas.0409598102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Armaz Aschrafi, Bruce A. Cunningham, Gerald M. Edelman, and Peter W. Vanderklish

The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain
PNAS 2005 102: 2180-2185; published online before print January 31 2005, 10.1073/pnas.0409803102 [Abstract] [Full Text] [Figures Only] [PDF]  

Pharmacology

Kevin R. Smith, Kent E. Pinkerton, Takaho Watanabe, Theresa L. Pedersen, Seung Jin Ma, and Bruce D. Hammock

Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor
PNAS 2005 102: 2186-2191; published online before print January 31 2005, 10.1073/pnas.0409591102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Physiology

Junichiro Sonoda, Ling Wa Chong, Michael Downes, Grant D. Barish, Sally Coulter, Christopher Liddle, Chih-Hao Lee, and Ronald M. Evans

Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites
PNAS 2005 102: 2198-2203; published online before print January 25 2005, 10.1073/pnas.0409481102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  
See Commentary on page 2675

Ishwar S. Parhar, Satoshi Ogawa, and Yasuo Sakuma Three GnRH receptor types in laser-captured single cells of the cichlid pituitary display cellular and functional heterogeneity PNAS 2005 102: 2204-2209; published online before print January 27 2005, 10.1073/pnas.0409494102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table] OPEN ACCESS ARTICLE

Antonio M. Pregueiro, Nathan Price-Lloyd, Deborah Bell-Pedersen, Christian Heintzen, Jennifer J. Loros, and Jay C. Dunlap From The Cover: Assignment of an essential role for the Neurospora frequency gene in circadian entrainment to temperature cycles PNAS 2005 102: 2210-2215; published online before print January 26 2005, 10.1073/pnas.0406506102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]

Christoph O. Randak and Michael J. Welsh

ADP inhibits function of the ABC transporter cystic fibrosis transmembrane conductance regulator via its adenylate kinase activity
PNAS 2005 102: 2216-2220; published online before print January 31 2005, 10.1073/pnas.0409787102 [Abstract] [Full Text] [Figures Only] [PDF]  

Plant Biology

Aaron H. Liepman, Curtis G. Wilkerson, and Kenneth Keegstra

Expression of cellulose synthase-like (Csl) genes in insect cells reveals that CslA family members encode mannan synthases
PNAS 2005 102: 2221-2226; published online before print January 12 2005, 10.1073/pnas.0409179102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  
See Commentary on page 1815

Insoon Kim, Euna Cho, Katrina Crawford, Frederick D. Hempel, and Patricia C. Zambryski

Cell-to-cell movement of GFP during embryogenesis and early seedling development in Arabidopsis
PNAS 2005 102: 2227-2231; published online before print January 24 2005, 10.1073/pnas.0409193102 [Abstract] [Full Text] [Figures Only] [PDF]  
See Commentary on page 1817

Alan Lloyd, Christopher L. Plaisier, Dana Carroll, and Gary N. Drews

Targeted mutagenesis using zinc-finger nucleases in Arabidopsis
PNAS 2005 102: 2232-2237; published online before print January 26 2005, 10.1073/pnas.0409339102 [Abstract] [Full Text] [Figures Only] [PDF]  

John S. Greenwood, Michael Helm, and Christine Gietl

Ricinosomes and endosperm transfer cell structure in programmed cell death of the nucellus during Ricinus seed development
PNAS 2005 102: 2238-2243; published online before print January 31 2005, 10.1073/pnas.0409429102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Psychology

David Alais and Simon Carlile

Synchronizing to real events: Subjective audiovisual alignment scales with perceived auditory depth and speed of sound
PNAS 2005 102: 2244-2247; published online before print January 24 2005, 10.1073/pnas.0407034102 [Abstract] [Full Text] [Figures Only] [PDF]  

CORRECTIONS

Correction for Nicolas et al., Cell mechanosensitivity controls the anisotropy of focal adhesions, PNAS 2004 101:12520-12525 [Full Text] [PDF]