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IN THIS ISSUE

This Week in PNAS
PNAS 2005 102: 2261. [Full Text] [Figures Only] [PDF]  

COMMENTARIES

Christine D. Keating

Nanoscience enables ultrasensitive detection of Alzheimer's biomarker
PNAS 2005 102: 2263-2264; published online before print February 9 2005, 10.1073/pnas.0500024102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 2273

Jeffrey Skolnick

Putting the pathway back into protein folding
PNAS 2005 102: 2265-2266; published online before print February 9 2005, 10.1073/pnas.0500128102 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 2362

Ron Hoy

Animal awareness: The (un)binding of multisensory cues in decision making by animals
PNAS 2005 102: 2267-2268; published online before print February 9 2005, 10.1073/pnas.0500093102 [Extract] [Full Text] [PDF]  
See companion article on page 2425

Vincent Moulton

Tracking down noncoding RNAs
PNAS 2005 102: 2269-2270; published online before print February 9 2005, 10.1073/pnas.0500129102 [Extract] [Full Text] [PDF]  
See companion article on page 2454

Susan Goldin-Meadow

Watching language grow
PNAS 2005 102: 2271-2272; published online before print February 9 2005, 10.1073/pnas.0500166102 [Extract] [Full Text] [PDF]  
See companion article on page 2661

PHYSICAL SCIENCES

Applied Physical Sciences

Idan Tuval, Luis Cisneros, Christopher Dombrowski, Charles W. Wolgemuth, John O. Kessler, and Raymond E. Goldstein

Bacterial swimming and oxygen transport near contact lines
PNAS 2005 102: 2277-2282; published online before print February 7 2005, 10.1073/pnas.0406724102 [Abstract] [Full Text] [Figures Only] [PDF]  

John R. Spear, Jeffrey J. Walker, Thomas M. McCollom, and Norman R. Pace From The Cover: Hydrogen and bioenergetics in the Yellowstone geothermal ecosystem PNAS 2005 102: 2555-2560; published online before print January 25 2005, 10.1073/pnas.0409574102 [Abstract] [Full Text] [Figures Only] [PDF]   See Commentary on page 3889

Chemistry

Hairong Ma and Martin Gruebele

Kinetics are probe-dependent during downhill folding of an engineered _6–85 protein
PNAS 2005 102: 2283-2287; published online before print February 7 2005, 10.1073/pnas.0409270102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Tina M. Hunter, Iain W. McNae, Xiangyang Liang, Juraj Bella, Simon Parsons, Malcolm D. Walkinshaw, and Peter J. Sadler

Protein recognition of macrocycles: Binding of anti-HIV metallocyclams to lysozyme
PNAS 2005 102: 2288-2292; published online before print February 8 2005, 10.1073/pnas.0407595102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Michael Samoilov, Sergey Plyasunov, and Adam P. Arkin

Stochastic amplification and signaling in enzymatic futile cycles through noise-induced bistability with oscillations
PNAS 2005 102: 2310-2315; published online before print February 8 2005, 10.1073/pnas.0406841102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Computer Sciences

Engineering

Physics

Chaoming Song, Ping Wang, and Hernán A. Makse

Experimental measurement of an effective temperature for jammed granular materials
PNAS 2005 102: 2299-2304; published online before print February 8 2005, 10.1073/pnas.0409911102 [Abstract] [Full Text] [Figures Only] [PDF]  

SOCIAL SCIENCES

Anthropology

Social Sciences

Hannelore Brandt and Karl Sigmund

Indirect reciprocity, image scoring, and moral hazard
PNAS 2005 102: 2666-2670; published online before print February 4 2005, 10.1073/pnas.0407370102 [Abstract] [Full Text] [Figures Only] [PDF]  

BIOLOGICAL SCIENCES

Biochemistry

Ramon K. Tabtiang, Brent O. Cezairliyan, Robert A. Grant, Jesse C. Cochrane, and Robert T. Sauer

Consolidating critical binding determinants by noncyclic rearrangement of protein secondary structure
PNAS 2005 102: 2305-2309; published online before print February 2 2005, 10.1073/pnas.0409562102 [Abstract] [Full Text] [Figures Only] [PDF]  

Michael Samoilov, Sergey Plyasunov, and Adam P. Arkin

Stochastic amplification and signaling in enzymatic futile cycles through noise-induced bistability with oscillations
PNAS 2005 102: 2310-2315; published online before print February 8 2005, 10.1073/pnas.0406841102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Thomas R. Sundermeier, Daniel P. Dulebohn, Hye Jin Cho, and A. Wali Karzai

A previously uncharacterized role for small protein B (SmpB) in transfer messenger RNA-mediated trans-translation
PNAS 2005 102: 2316-2321; published online before print February 7 2005, 10.1073/pnas.0409694102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Hammou Oubrahim, Jun Wang, Earl R. Stadtman, and P. Boon Chock Molecular cloning and characterization of murine caspase-12 gene promoter PNAS 2005 102: 2322-2327; published online before print February 8 2005, 10.1073/pnas.0409874102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Sandra E. Nicholson, Donald Metcalf, Naomi S. Sprigg, Ruth Columbus, Francesca Walker, Anabel Silva, Dale Cary, Tracy A. Willson, Jian-Guo Zhang, Douglas J. Hilton, Warren S. Alexander, and Nicos A. Nicola

Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling
PNAS 2005 102: 2328-2333; published online before print February 3 2005, 10.1073/pnas.0409675102 [Abstract] [Full Text] [Figures Only] [PDF]  

Gali Prag, Sangho Lee, Rafael Mattera, Cecilia N. Arighi, Bridgette M. Beach, Juan S. Bonifacino, and James H. Hurley

Structural mechanism for ubiquitinated-cargo recognition by the Golgi-localized, -ear-containing, ADP-ribosylation-factor-binding proteins
PNAS 2005 102: 2334-2339; published online before print February 8 2005, 10.1073/pnas.0500118102 [Abstract] [Full Text] [Figures Only] [PDF]  

Francisco J. Schopfer, Yiming Lin, Paul R. S. Baker, Taixing Cui, Minerva Garcia-Barrio, Jifeng Zhang, Kai Chen, Yuqing E. Chen, and Bruce A. Freeman

Nitrolinoleic acid: An endogenous peroxisome proliferator-activated receptor ligand
PNAS 2005 102: 2340-2345; published online before print February 8 2005, 10.1073/pnas.0408384102 [Abstract] [Full Text] [Figures Only] [PDF]  

Aseem Z. Ansari, Anuja Ogirala, and Mark Ptashne

Transcriptional activating regions target attached substrates to a cyclin-dependent kinase
PNAS 2005 102: 2346-2349; published online before print February 1 2005, 10.1073/pnas.0409671102 [Abstract] [Full Text] [Figures Only] [PDF]  

Jeonghee Cho and Philip N. Tsichlis

Phosphorylation at Thr-290 regulates Tpl2 binding to NF-B1/p105 and Tpl2 activation and degradation by lipopolysaccharide
PNAS 2005 102: 2350-2355; published online before print February 7 2005, 10.1073/pnas.0409856102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Meihong Chen, Lishu Zhang, Hong-Yan Zhang, Xiahui Xiong, Bo Wang, Quan Du, Bing Lu, Claes Wahlestedt, and Zicai Liang

A universal plasmid library encoding all permutations of small interfering RNA
PNAS 2005 102: 2356-2361; published online before print February 4 2005, 10.1073/pnas.0401549101 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Biophysics

Adam Liwo, Mey Khalili, and Harold A. Scheraga

Ab initio simulations of protein-folding pathways by molecular dynamics with the united-residue model of polypeptide chains
PNAS 2005 102: 2362-2367; published online before print January 26 2005, 10.1073/pnas.0408885102 [Abstract] [Full Text] [Figures Only] [PDF]  
See Commentary on page 2265

Ophir Flomenbom, Kelly Velonia, Davey Loos, Sadahiro Masuo, Mircea Cotlet, Yves Engelborghs, Johan Hofkens, Alan E. Rowan, Roeland J. M. Nolte, Mark Van der Auweraer, Frans C. de Schryver, and Joseph Klafter

Stretched exponential decay and correlations in the catalytic activity of fluctuating single lipase molecules
PNAS 2005 102: 2368-2372; published online before print February 4 2005, 10.1073/pnas.0409039102 [Abstract] [Full Text] [Figures Only] [PDF]  

Yaakov Levy, Samuel S. Cho, Tongye Shen, José N. Onuchic, and Peter G. Wolynes

Symmetry and frustration in protein energy landscapes: A near degeneracy resolves the Rop dimer-folding mystery
PNAS 2005 102: 2373-2378; published online before print February 8 2005, 10.1073/pnas.0409572102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Jens Bredenbeck, Jan Helbing, Janet R. Kumita, G. Andrew Woolley, and Peter Hamm

-Helix formation in a photoswitchable peptide tracked from picoseconds to microseconds by time-resolved IR spectroscopy
PNAS 2005 102: 2379-2384; published online before print February 7 2005, 10.1073/pnas.0406948102 [Abstract] [Full Text] [Figures Only] [PDF]  

Krishnananda Chattopadhyay, Elliot L. Elson, and Carl Frieden

The kinetics of conformational fluctuations in an unfolded protein measured by fluorescence methods
PNAS 2005 102: 2385-2389; published online before print February 8 2005, 10.1073/pnas.0500127102 [Abstract] [Full Text] [Figures Only] [PDF]  

Olivia du Roure, Alexandre Saez, Axel Buguin, Robert H. Austin, Philippe Chavrier, Pascal Silberzan, and Benoit Ladoux

Force mapping in epithelial cell migration
PNAS 2005 102: 2390-2395; published online before print February 4 2005, 10.1073/pnas.0408482102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Cell Biology

Ralf Kittler, Laurence Pelletier, Chunling Ma, Ina Poser, Steffi Fischer, Anthony A. Hyman, and Frank Buchholz

RNA interference rescue by bacterial artificial chromosome transgenesis in mammalian tissue culture cells
PNAS 2005 102: 2396-2401; published online before print February 3 2005, 10.1073/pnas.0409861102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

M. Estela Campanella, Haiyan Chu, and Philip S. Low

Assembly and regulation of a glycolytic enzyme complex on the human erythrocyte membrane
PNAS 2005 102: 2402-2407; published online before print February 8 2005, 10.1073/pnas.0409741102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

James R. Stringer, Jon S. Larson, Jared M. Fischer, Mario Medvedovic, Megan N. Hersh, Gregory P. Boivin, and Saundra L. Stringer

Modeling variation in tumors in vivo
PNAS 2005 102: 2408-2413; published online before print February 3 2005, 10.1073/pnas.0401340102 [Abstract] [Full Text] [Figures Only] [PDF]  

Developmental Biology

Yasuhiko Kawakami, Masanao Tsuda, Shigeru Takahashi, Noboru Taniguchi, Concepción Rodríguez Esteban, Michihisa Zemmyo, Takayuki Furumatsu, Martin Lotz, Juan Carlos Izpisúa Belmonte, and Hiroshi Asahara

Transcriptional coactivator PGC-1 regulates chondrogenesis via association with Sox9
PNAS 2005 102: 2414-2419; published online before print February 7 2005, 10.1073/pnas.0407510102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Haiyan Lei, Hailong Wang, Aster H. Juan, and Frank H. Ruddle

The identification of Hoxc8 target genes
PNAS 2005 102: 2420-2424; published online before print February 7 2005, 10.1073/pnas.0409700102 [Abstract] [Full Text] [Figures Only] [PDF]  

Ecology

Evolution

Yoichi Tanabe, Mitsuyasu Hasebe, Hiroyuki Sekimoto, Tomoaki Nishiyama, Masakazu Kitani, Katrin Henschel, Thomas Münster, Günter Theissen, Hisayoshi Nozaki, and Motomi Ito

Characterization of MADS-box genes in charophycean green algae and its implication for the evolution of MADS-box genes
PNAS 2005 102: 2436-2441; published online before print February 7 2005, 10.1073/pnas.0409860102 [Abstract] [Full Text] [Figures Only] [PDF]  

Peter L. Morrell, Donna M. Toleno, Karen E. Lundy, and Michael T. Clegg

Low levels of linkage disequilibrium in wild barley (Hordeum vulgare ssp. spontaneum) despite high rates of self-fertilization
PNAS 2005 102: 2442-2447; published online before print February 7 2005, 10.1073/pnas.0409804102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Genetics

Stefan Washietl, Ivo L. Hofacker, and Peter F. Stadler From The Cover: Fast and reliable prediction of noncoding RNAs PNAS 2005 102: 2454-2459; published online before print January 21 2005, 10.1073/pnas.0409169102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]   See Commentary on page 2269

Jonathan D. Werner, Justin O. Borevitz, Norman Warthmann, Gabriel T. Trainer, Joseph R. Ecker, Joanne Chory, and Detlef Weigel

Quantitative trait locus mapping and DNA array hybridization identify an FLM deletion as a cause for natural flowering-time variation
PNAS 2005 102: 2460-2465; published online before print February 4 2005, 10.1073/pnas.0409474102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Immunology

Ali A. Zarrin, Ming Tian, Jing Wang, Tiffany Borjeson, and Frederick W. Alt

Influence of switch region length on immunoglobulin class switch recombination
PNAS 2005 102: 2466-2470; published online before print January 31 2005, 10.1073/pnas.0409847102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Sean Rooney, Frederick W. Alt, JoAnn Sekiguchi, and John P. Manis

Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and development
PNAS 2005 102: 2471-2475; published online before print February 7 2005, 10.1073/pnas.0409857102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Yibing Wang, Anatoyla Rubtsov, Ryan Heiser, Janice White, Frances Crawford, Philippa Marrack, and John W. Kappler Using a baculovirus display library to identify MHC class I mimotopes PNAS 2005 102: 2476-2481; published online before print February 7 2005, 10.1073/pnas.0409798102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Keiichiro Suzuki, Bob Meek, Yasuko Doi, Tasuku Honjo, and Sidonia Fagarasan

Two distinctive pathways for recruitment of naïve and primed IgM⁺ B cells to the gut lamina propria
PNAS 2005 102: 2482-2486; published online before print February 3 2005, 10.1073/pnas.0409539102 [Abstract] [Full Text] [Figures Only] [PDF]  

Thomas R. Hawn, Annelies Verbon, Marta Janer, Lue Ping Zhao, Bruce Beutler, and Alan Aderem

Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
PNAS 2005 102: 2487-2489; published online before print February 7 2005, 10.1073/pnas.0409831102 [Abstract] [Full Text] [PDF]  

Medical Sciences

Tiffany Brake and Paul F. Lambert

Estrogen contributes to the onset, persistence, and malignant progression of cervical cancer in a human papillomavirus-transgenic mouse model
PNAS 2005 102: 2490-2495; published online before print February 7 2005, 10.1073/pnas.0409883102 [Abstract] [Full Text] [Figures Only] [PDF]  

Lynn E. Macdonald, Katherine E. Wortley, Lori C. Gowen, Keith D. Anderson, Jane D. Murray, William T. Poueymirou, Mary V. Simmons, Dianna Barber, David M. Valenzuela, Aris N. Economides, Stanley J. Wiegand, George D. Yancopoulos, Mark W. Sleeman, and Andrew J. Murphy Resistance to diet-induced obesity in mice globally overexpressing OGH/GPB5 PNAS 2005 102: 2496-2501; published online before print February 7 2005, 10.1073/pnas.0409849102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Zongyu Zheng, Kai M. Schmidt-Ott, Streamson Chua, Kirk A. Foster, Rachelle Z. Frankel, Paul Pavlidis, Jonathan Barasch, Vivette D. D'Agati, and Ali G. Gharavi

A Mendelian locus on chromosome 16 determines susceptibility to doxorubicin nephropathy in the mouse
PNAS 2005 102: 2502-2507; published online before print February 7 2005, 10.1073/pnas.0409786102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Xue-Song Wu, Li Xin, Wen-Xuan Yin, Xi-Ying Shang, Lu Lu, Rory M. Watt, Kathryn S. E. Cheah, Jian-Dong Huang, De-Pei Liu, and Chih-Chuan Liang

Increased efficiency of oligonucleotide-mediated gene repair through slowing replication fork progression
PNAS 2005 102: 2508-2513; published online before print February 4 2005, 10.1073/pnas.0406991102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Eleonora Palma, Gabriele Spinelli, Gregorio Torchia, A. Martinez-Torres, Davide Ragozzino, Ricardo Miledi, and Fabrizio Eusebi

Abnormal GABA_A receptors from the human epileptic hippocampal subiculum microtransplanted to Xenopus oocytes
PNAS 2005 102: 2514-2518; published online before print February 3 2005, 10.1073/pnas.0409687102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Kathryn R. Wagner, Xiaosong Liu, Xiaoli Chang, and Ronald E. Allen Muscle regeneration in the prolonged absence of myostatin PNAS 2005 102: 2519-2524; published online before print February 7 2005, 10.1073/pnas.0408729102 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Siva Kumar Kolluri, Maripat Corr, Sharon Y. James, Michele Bernasconi, Desheng Lu, Wen Liu, Howard B. Cottam, Lorenzo M. Leoni, Dennis A. Carson, and Xiao-kun Zhang The R-enantiomer of the nonsteroidal antiinflammatory drug etodolac binds retinoid X receptor and induces tumor-selective apoptosis PNAS 2005 102: 2525-2530; published online before print February 7 2005, 10.1073/pnas.0409721102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

John R. Pawloski, Douglas T. Hess, and Jonathan S. Stamler

Impaired vasodilation by red blood cells in sickle cell disease
PNAS 2005 102: 2531-2536; published online before print February 7 2005, 10.1073/pnas.0409876102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jason M. Montez, Alex Soukas, Esra Asilmaz, Gulnorakhon Fayzikhodjaeva, Giamila Fantuzzi, and Jeffrey M. Friedman

Acute leptin deficiency, leptin resistance, and the physiologic response to leptin withdrawal
PNAS 2005 102: 2537-2542; published online before print February 7 2005, 10.1073/pnas.0409530102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Christopher C. Chadwick, Susan Chippari, Edward Matelan, Lisa Borges-Marcucci, Amy M. Eckert, James C. Keith, Jr., Leo M. Albert, Yelena Leathurby, Heather A. Harris, Ramesh A. Bhat, Mark Ashwell, Eugene Trybulski, Richard C. Winneker, Steven J. Adelman, Robert J. Steffan, and Douglas C. Harnish

Identification of pathway-selective estrogen receptor ligands that inhibit NF-B transcriptional activity
PNAS 2005 102: 2543-2548; published online before print February 7 2005, 10.1073/pnas.0405841102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Microbiology

Jeff H. Chang, Jonathan M. Urbach, Terry F. Law, Larry W. Arnold, An Hu, Saurabh Gombar, Sarah R. Grant, Frederick M. Ausubel, and Jeffery L. Dangl

A high-throughput, near-saturating screen for type III effector genes from Pseudomonas syringae
PNAS 2005 102: 2549-2554; published online before print February 8 2005, 10.1073/pnas.0409660102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  
See Commentary on page 3527

John R. Spear, Jeffrey J. Walker, Thomas M. McCollom, and Norman R. Pace From The Cover: Hydrogen and bioenergetics in the Yellowstone geothermal ecosystem PNAS 2005 102: 2555-2560; published online before print January 25 2005, 10.1073/pnas.0409574102 [Abstract] [Full Text] [Figures Only] [PDF]   See Commentary on page 3889

Sharookh B. Kapadia and Francis V. Chisari

Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids
PNAS 2005 102: 2561-2566; published online before print February 7 2005, 10.1073/pnas.0409834102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Konstantinos T. Konstantinidis and James M. Tiedje

Genomic insights that advance the species definition for prokaryotes
PNAS 2005 102: 2567-2572; published online before print February 8 2005, 10.1073/pnas.0409727102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Yiorgos Apidianakis, Michael N. Mindrinos, Wenzhong Xiao, Gee W. Lau, Regina L. Baldini, Ronald W. Davis, and Laurence G. Rahme

Profiling early infection responses: Pseudomonas aeruginosa eludes host defenses by suppressing antimicrobial peptide gene expression
PNAS 2005 102: 2573-2578; published online before print February 4 2005, 10.1073/pnas.0409588102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Theo Heller, Satoru Saito, Jonathan Auerbach, Tarice Williams, Tzivia Rachel Moreen, Allison Jazwinski, Brian Cruz, Neha Jeurkar, Ronda Sapp, Guangxiang Luo, and T. Jake Liang

An in vitro model of hepatitis C virion production
PNAS 2005 102: 2579-2583; published online before print February 8 2005, 10.1073/pnas.0409666102 [Abstract] [Full Text] [Figures Only] [PDF]  

Shizuo G. Kamita, Koukichi Nagasaka, Josie W. Chua, Toru Shimada, Kazuei Mita, Masahiko Kobayashi, Susumu Maeda, and Bruce D. Hammock

A baculovirus-encoded protein tyrosine phosphatase gene induces enhanced locomotory activity in a lepidopteran host
PNAS 2005 102: 2584-2589; published online before print February 7 2005, 10.1073/pnas.0409457102 [Abstract] [Full Text] [Figures Only] [PDF]  

Neuroscience

Yu-Qing Cao and Richard W. Tsien Effects of familial hemiplegic migraine type 1 mutations on neuronal P/Q-type Ca2+ channel activity and inhibitory synaptic transmission PNAS 2005 102: 2590-2595; published online before print February 7 2005, 10.1073/pnas.0409896102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Nam Le, Rakesh Nagarajan, James Y. T. Wang, Toshiyuki Araki, Robert E. Schmidt, and Jeffrey Milbrandt

Analysis of congenital hypomyelinating Egr2^Lo/Lo nerves identifies Sox2 as an inhibitor of Schwann cell differentiation and myelination
PNAS 2005 102: 2596-2601; published online before print February 3 2005, 10.1073/pnas.0407836102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Tie-Shan Tang, Elizabeth Slow, Vitalie Lupu, Irina G. Stavrovskaya, Mutsuyuki Sugimori, Rodolfo Llinás, Bruce S. Kristal, Michael R. Hayden, and Ilya Bezprozvanny

Disturbed Ca²⁺ signaling and apoptosis of medium spiny neurons in Huntington's disease
PNAS 2005 102: 2602-2607; published online before print February 3 2005, 10.1073/pnas.0409402102 [Abstract] [Full Text] [Figures Only] [PDF]  

Seung-Hee Yoo, Caroline H. Ko, Phillip L. Lowrey, Ethan D. Buhr, Eun-joo Song, Suhwan Chang, Ook Joon Yoo, Shin Yamazaki, Choogon Lee, and Joseph S. Takahashi A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo PNAS 2005 102: 2608-2613; published online before print February 7 2005, 10.1073/pnas.0409763102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Samuel M. Young, Jr.

Proteolysis of SNARE proteins alters facilitation and depression in a specific way
PNAS 2005 102: 2614-2619; published online before print February 3 2005, 10.1073/pnas.0409656102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Alon M. Chen, Marilyn H. Perrin, Michael R. DiGruccio, Joan M. Vaughan, Bhawanjit K. Brar, Carlos M. Arias, Kathy A. Lewis, Jean E. Rivier, Paul E. Sawchenko, and Wylie W. Vale

A soluble mouse brain splice variant of type 2 corticotropin-releasing factor (CRF) receptor binds ligands and modulates their activity
PNAS 2005 102: 2620-2625; published online before print February 8 2005, 10.1073/pnas.0409583102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Florin Dolcos, Kevin S. LaBar, and Roberto Cabeza

Remembering one year later: Role of the amygdala and the medial temporal lobe memory system in retrieving emotional memories
PNAS 2005 102: 2626-2631; published online before print February 9 2005, 10.1073/pnas.0409848102 [Abstract] [Full Text] [Figures Only] [PDF]  

Pharmacology

Hermes J. Garbán, Diana C. Márquez-Garbán, Richard J. Pietras, and Louis J. Ignarro

Rapid nitric oxide-mediated S-nitrosylation of estrogen receptor: Regulation of estrogen-dependent gene transcription
PNAS 2005 102: 2632-2636; published online before print February 7 2005, 10.1073/pnas.0409854102 [Abstract] [Full Text] [Figures Only] [PDF]  

Physiology

Anthony Falluel-Morel, David Vaudry, Nicolas Aubert, Ludovic Galas, Magalie Benard, Magali Basille, Marc Fontaine, Alain Fournier, Hubert Vaudry, and Bruno J. Gonzalez

Pituitary adenylate cyclase-activating polypeptide prevents the effects of ceramides on migration, neurite outgrowth, and cytoskeleton remodeling
PNAS 2005 102: 2637-2642; published online before print February 4 2005, 10.1073/pnas.0409681102 [Abstract] [Full Text] [Figures Only] [PDF]  

Svetlana V. Komarova, Alexey Pereverzev, Jonathan W. Shum, Stephen M. Sims, and S. Jeffrey Dixon

Convergent signaling by acidosis and receptor activator of NF-B ligand (RANKL) on the calcium/calcineurin/NFAT pathway in osteoclasts
PNAS 2005 102: 2643-2648; published online before print February 4 2005, 10.1073/pnas.0406874102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Plant Biology

Ivan R. Baxter, Jeffery C. Young, Gordon Armstrong, Nathan Foster, Naomi Bogenschutz, Tatiana Cordova, Wendy Ann Peer, Samuel P. Hazen, Angus S. Murphy, and Jeffrey F. Harper

A plasma membrane H⁺-ATPase is required for the formation of proanthocyanidins in the seed coat endothelium of Arabidopsis thaliana
PNAS 2005 102: 2649-2654; published online before print February 4 2005, 10.1073/pnas.0406377102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

René Mathis, Frédérique Van Gijsegem, Riet De Rycke, Wim D'Haeze, Els Van Maelsaeke, Erin Anthonio, Marc Van Montagu, Marcelle Holsters, and Danny Vereecke

Lipopolysaccharides as a communication signal for progression of legume endosymbiosis
PNAS 2005 102: 2655-2660; published online before print February 7 2005, 10.1073/pnas.0409816102 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

CORRECTIONS

Correction for Syková et al., Changes in extracellular space size and geometry in APP23 transgenic mice: A model of Alzheimer's disease, PNAS 2005 102:479-484 [Extract] [Full Text] [PDF]