Table of Contents

This Week in PNAS

This Week in PNAS:
In This Issue
PNAS 2006 103:14643-14644; doi:10.1073/iti4006103

Commentaries

Commentary:
- Andrew Hiatt
- and Michael Pauly
Monoclonal antibodies from plants: A new speed record
PNAS 2006 103:14645-14646; published ahead of print September 25, 2006, doi:10.1073/pnas.0607089103
- See companion article on page 14701 in issue 40 of volume 103
Commentary:
- Shosuke Ito
Encapsulation of a reactive core in neuromelanin
PNAS 2006 103:14647-14648; published ahead of print September 27, 2006, doi:10.1073/pnas.0606879103
- See companion article on page 14785 in issue 40 of volume 103
Commentary:
- Nicholas A. Williamson,
- Jamie Rossjohn,
- and Anthony W. Purcell
Tumors reveal their secrets to cytotoxic T cells
PNAS 2006 103:14649-14650; published ahead of print September 27, 2006, doi:10.1073/pnas.0606951103
- See companion article on page 14889 in issue 40 of volume 103
Commentary:
- Scott H. Kaufmann
Imatinib spells BAD news for Bcr/abl-positive leukemias
PNAS 2006 103:14651-14652; published ahead of print September 26, 2006, doi:10.1073/pnas.0607135103
- See companion article on page 14907 in issue 40 of volume 103

Perspective

Select this article
Perspective:
- R. W. Kates,
- C. E. Colten,
- S. Laska,
- and S. P. Leatherman
Reconstruction of New Orleans after Hurricane Katrina: A research perspective
PNAS 2006 103:14653-14660; published ahead of print September 26, 2006, doi:10.1073/pnas.0605726103

Profile

Profile:
- Tinsley H. Davis
Profile of Daniel J. Cosgrove
PNAS 2006 103:14661-14663; published ahead of print September 26, 2006, doi:10.1073/pnas.0606828103
- See commentary article on page 14664 in issue 40 of volume 103

From the Academy

Select this article
From the Academy - Biological Sciences - Biochemistry:
- Einat Sprinzak,
- Yael Altuvia,
- and Hanah Margalit
Colloquium Papers: Characterization and prediction of protein–protein interactions within and between complexes
PNAS 2006 103:14718-14723; published ahead of print September 26, 2006, doi:10.1073/pnas.0603352103
Select this article
From the Academy - Biological Sciences - Biochemistry:
- Haiyuan Yu
- and Mark Gerstein
Colloquium Papers: Genomic analysis of the hierarchical structure of regulatory networks
PNAS 2006 103:14724-14731; published ahead of print September 26, 2006, doi:10.1073/pnas.0508637103

Bilogocal Sciences

Immunology

Select this article
Bilogocal Sciences - Immunology:
- Jeffrey Combs,
- Soo Jin Kim,
- Sarah Tan,
- Lee A. Ligon,
- Erika L. F. Holzbaur,
- Jeffrey Kuhn,
- and Martin Poenie
Recruitment of dynein to the Jurkat immunological synapse
PNAS 2006 103:14883-14888; published ahead of print September 21, 2006, doi:10.1073/pnas.0600914103

Physical Sciences

Applied Physical Sciences

Select this article
Physical Sciences - Applied Physical Sciences - Biological Sciences - Biophysics:
- AmirAli H. Talasaz,
- Mohsen Nemat-Gorgani,
- Yang Liu,
- Patrik Ståhl,
- Robert W. Dutton,
- Mostafa Ronaghi,
- and Ronald W. Davis
Prediction of protein orientation upon immobilization on biological and nonbiological surfaces
PNAS 2006 103:14773-14778; published ahead of print September 25, 2006, doi:10.1073/pnas.0605841103
Open Access Article

Chemistry

Select this article
Physical Sciences - Chemistry:
- K. Subburaman,
- N. Pernodet,
- S. Y. Kwak,
- E. DiMasi,
- S. Ge,
- V. Zaitsev,
- X. Ba,
- N. L. Yang,
- and M. Rafailovich
Templated biomineralization on self-assembled protein fibers
PNAS 2006 103:14672-14677; published ahead of print September 26, 2006, doi:10.1073/pnas.0602952103
Select this article
Physical Sciences - Chemistry - Biological Sciences - Biochemistry:
- Nicola J. Baxter,
- Luis F. Olguin,
- Marko Goličnik,
- Guoqiang Feng,
- Andrea M. Hounslow,
- Wolfgang Bermel,
- G. Michael Blackburn,
- Florian Hollfelder,
- Jonathan P. Waltho,
- and Nicholas H. Williams
A Trojan horse transition state analogue generated by MgF 3 − formation in an enzyme active site
PNAS 2006 103:14732-14737; published ahead of print September 21, 2006, doi:10.1073/pnas.0604448103
Select this article
Physical Sciences - Chemistry - Biological Sciences - Immunology:
- Angela L. Zarling,
- Joy M. Polefrone,
- Anne M. Evans,
- Leann M. Mikesh,
- Jeffrey Shabanowitz,
- Sarah T. Lewis,
- Victor H. Engelhard,
- and Donald F. Hunt
From the Cover: Identification of class I MHC-associated phosphopeptides as targets for cancer immunotherapy
PNAS 2006 103:14889-14894; published ahead of print September 25, 2006, doi:10.1073/pnas.0604045103
- See commentary article on page 14649 in issue 40 of volume 103

Engineering

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Physical Sciences - Engineering:
- Yuliya Vengrenyuk,
- Stéphane Carlier,
- Savvas Xanthos,
- Luis Cardoso,
- Peter Ganatos,
- Renu Virmani,
- Shmuel Einav,
- Lane Gilchrist,
- and Sheldon Weinbaum
A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps
PNAS 2006 103:14678-14683; published ahead of print September 26, 2006, doi:10.1073/pnas.0606310103

Geology

Select this article
Physical Sciences - Geology - Biological Sciences - Environmental Sciences:
- Kai-Uwe Hinrichs,
- John M. Hayes,
- Wolfgang Bach,
- Arthur J. Spivack,
- Laura R. Hmelo,
- Nils G. Holm,
- Carl G. Johnson,
- and Sean P. Sylva
Biological formation of ethane and propane in the deep marine subsurface
PNAS 2006 103:14684-14689; published ahead of print September 21, 2006, doi:10.1073/pnas.0606535103

Geophysics

Select this article
Physical Sciences - Geophysics:
- R. Tulloch
- and K. S. Smith
From the Cover: A theory for the atmospheric energy spectrum: Depth-limited temperature anomalies at the tropopause
PNAS 2006 103:14690-14694; published ahead of print September 25, 2006, doi:10.1073/pnas.0605494103

Physics

Select this article
Physical Sciences - Physics:
- Qingsong Zhang,
- Tahir Cagin,
- and William A. Goddard, III
The ferroelectric and cubic phases in BaTiO 3 ferroelectrics are also antiferroelectric
PNAS 2006 103:14695-14700; published ahead of print September 25, 2006, doi:10.1073/pnas.0606612103
Select this article
Biological Sciences - Biophysics - Physical Sciences - Physics:
- John A. Davis,
- David W. Inglis,
- Keith J. Morton,
- David A. Lawrence,
- Lotien R. Huang,
- Stephen Y. Chou,
- James C. Sturm,
- and Robert H. Austin
Deterministic hydrodynamics: Taking blood apart
PNAS 2006 103:14779-14784; published ahead of print September 25, 2006, doi:10.1073/pnas.0605967103

Social Sciences

Psychology

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Biological Sciences - Neuroscience - Social Sciences - Psychology:
- Chia-huei Tseng,
- Joetta L. Gobell,
- Zhong-Lin Lu,
- and George Sperling
When motion appears stopped: Stereo motion standstill
PNAS 2006 103:14953-14958; published ahead of print September 26, 2006, doi:10.1073/pnas.0606758103

Biological Sciences

Applied Biological Sciences

Select this article
Biological Sciences - Applied Biological Sciences:
- Anatoli Giritch,
- Sylvestre Marillonnet,
- Carola Engler,
- Gerben van Eldik,
- Johan Botterman,
- Victor Klimyuk,
- and Yuri Gleba
From the Cover: Rapid high-yield expression of full-size IgG antibodies in plants coinfected with noncompeting viral vectors
PNAS 2006 103:14701-14706; published ahead of print September 14, 2006, doi:10.1073/pnas.0606631103
Open Access Article
- See commentary article on page 14645 in issue 40 of volume 103
Select this article
Biological Sciences - Applied Biological Sciences:
- Tatjana Atanasijevic,
- Maxim Shusteff,
- Peter Fam,
- and Alan Jasanoff
Calcium-sensitive MRI contrast agents based on superparamagnetic iron oxide nanoparticles and calmodulin
PNAS 2006 103:14707-14712; published ahead of print September 26, 2006, doi:10.1073/pnas.0606749103
Select this article
Biological Sciences - Applied Biological Sciences:
- Rosie Woodroffe,
- Christl A. Donnelly,
- Helen E. Jenkins,
- W. Thomas Johnston,
- David R. Cox,
- F. John Bourne,
- Chris L. Cheeseman,
- Richard J. Delahay,
- Richard S. Clifton-Hadley,
- George Gettinby,
- Peter Gilks,
- R. Glyn Hewinson,
- John P. McInerney,
- and W. Ivan Morrison
Culling and cattle controls influence tuberculosis risk for badgers
PNAS 2006 103:14713-14717; published ahead of print October 2, 2006, doi:10.1073/pnas.0606251103
Open Access Article

Biochemistry

Select this article
From the Academy - Biological Sciences - Biochemistry:
- Einat Sprinzak,
- Yael Altuvia,
- and Hanah Margalit
Colloquium Papers: Characterization and prediction of protein–protein interactions within and between complexes
PNAS 2006 103:14718-14723; published ahead of print September 26, 2006, doi:10.1073/pnas.0603352103
Select this article
From the Academy - Biological Sciences - Biochemistry:
- Haiyuan Yu
- and Mark Gerstein
Colloquium Papers: Genomic analysis of the hierarchical structure of regulatory networks
PNAS 2006 103:14724-14731; published ahead of print September 26, 2006, doi:10.1073/pnas.0508637103
Select this article
Physical Sciences - Chemistry - Biological Sciences - Biochemistry:
- Nicola J. Baxter,
- Luis F. Olguin,
- Marko Goličnik,
- Guoqiang Feng,
- Andrea M. Hounslow,
- Wolfgang Bermel,
- G. Michael Blackburn,
- Florian Hollfelder,
- Jonathan P. Waltho,
- and Nicholas H. Williams
A Trojan horse transition state analogue generated by MgF 3 − formation in an enzyme active site
PNAS 2006 103:14732-14737; published ahead of print September 21, 2006, doi:10.1073/pnas.0604448103
Select this article
Biological Sciences - Biochemistry:
- Lee M. Hoffart,
- Eric W. Barr,
- Robert B. Guyer,
- J. Martin Bollinger, Jr.,
- and Carsten Krebs
Direct spectroscopic detection of a C-H-cleaving high-spin Fe(IV) complex in a prolyl-4-hydroxylase
PNAS 2006 103:14738-14743; published ahead of print September 26, 2006, doi:10.1073/pnas.0604005103
Open Access Article
Select this article
Biological Sciences - Biochemistry:
- Hiroshi M. Sasaki,
- Shun-ichi Sekine,
- Toru Sengoku,
- Ryuya Fukunaga,
- Motoyuki Hattori,
- Yukiko Utsunomiya,
- Chizu Kuroishi,
- Seiki Kuramitsu,
- Mikako Shirouzu,
- and Shigeyuki Yokoyama
Structural and mutational studies of the amino acid-editing domain from archaeal/eukaryal phenylalanyl-tRNA synthetase
PNAS 2006 103:14744-14749; published ahead of print September 26, 2006, doi:10.1073/pnas.0603182103
Select this article
Biological Sciences - Biochemistry:
- Fernando P. Molina-Heredia,
- Chantal Houée-Levin,
- Catherine Berthomieu,
- Danièle Touati,
- Emilie Tremey,
- Vincent Favaudon,
- Virgile Adam,
- and Vincent Nivière
Detoxification of superoxide without production of H 2 O 2 : Antioxidant activity of superoxide reductase complexed with ferrocyanide
PNAS 2006 103:14750-14755; published ahead of print September 25, 2006, doi:10.1073/pnas.0510828103
Select this article
Biological Sciences - Biochemistry:
- Olga Castro,
- Federico Movsichoff,
- and Armando J. Parodi
Preferential transfer of the complete glycan is determined by the oligosaccharyltransferase complex and not by the catalytic subunit
PNAS 2006 103:14756-14760; published ahead of print September 25, 2006, doi:10.1073/pnas.0607086103
Select this article
Biological Sciences - Biochemistry:
- Jérôme Vicogne,
- Daniel Vollenweider,
- Jeffery R. Smith,
- Ping Huang,
- Michael A. Frohman,
- and Jeffrey E. Pessin
Asymmetric phospholipid distribution drives in vitro reconstituted SNARE-dependent membrane fusion
PNAS 2006 103:14761-14766; published ahead of print September 25, 2006, doi:10.1073/pnas.0606881103
Select this article
Biological Sciences - Biochemistry:
- Matthew E. Cockman,
- David E. Lancaster,
- Ineke P. Stolze,
- Kirsty S. Hewitson,
- Michael A. McDonough,
- Mathew L. Coleman,
- Charlotte H. Coles,
- Xiaohong Yu,
- Ronald T. Hay,
- Steven C. Ley,
- Christopher W. Pugh,
- Neil J. Oldham,
- Norma Masson,
- Christopher J. Schofield,
- and Peter J. Ratcliffe
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
PNAS 2006 103:14767-14772; published ahead of print September 26, 2006, doi:10.1073/pnas.0606877103
Open Access Article

Biophysics

Select this article
Physical Sciences - Applied Physical Sciences - Biological Sciences - Biophysics:
- AmirAli H. Talasaz,
- Mohsen Nemat-Gorgani,
- Yang Liu,
- Patrik Ståhl,
- Robert W. Dutton,
- Mostafa Ronaghi,
- and Ronald W. Davis
Prediction of protein orientation upon immobilization on biological and nonbiological surfaces
PNAS 2006 103:14773-14778; published ahead of print September 25, 2006, doi:10.1073/pnas.0605841103
Open Access Article
Select this article
Biological Sciences - Biophysics - Physical Sciences - Physics:
- John A. Davis,
- David W. Inglis,
- Keith J. Morton,
- David A. Lawrence,
- Lotien R. Huang,
- Stephen Y. Chou,
- James C. Sturm,
- and Robert H. Austin
Deterministic hydrodynamics: Taking blood apart
PNAS 2006 103:14779-14784; published ahead of print September 25, 2006, doi:10.1073/pnas.0605967103
Select this article
Biological Sciences - Biophysics:
- William D. Bush,
- Jacob Garguilo,
- Fabio A. Zucca,
- Alberto Albertini,
- Luigi Zecca,
- Glenn S. Edwards,
- Robert J. Nemanich,
- and John D. Simon
From the Cover: The surface oxidation potential of human neuromelanin reveals a spherical architecture with a pheomelanin core and a eumelanin surface
PNAS 2006 103:14785-14789; published ahead of print September 25, 2006, doi:10.1073/pnas.0604010103
- See commentary article on page 14647 in issue 40 of volume 103
Select this article
Biological Sciences - Biophysics:
- Rachel Gueta,
- David Barlam,
- Roni Z. Shneck,
- and Itay Rousso
Measurement of the mechanical properties of isolated tectorial membrane using atomic force microscopy
PNAS 2006 103:14790-14795; published ahead of print September 25, 2006, doi:10.1073/pnas.0603429103
Select this article
Biological Sciences - Biophysics:
- Eftychia Pinakoulaki,
- Hideaki Yoshimura,
- Vangelis Daskalakis,
- Shiro Yoshioka,
- Shigetoshi Aono,
- and Constantinos Varotsis
Two ligand-binding sites in the O 2 -sensing signal transducer HemAT: Implications for ligand recognition/discrimination and signaling
PNAS 2006 103:14796-14801; published ahead of print September 26, 2006, doi:10.1073/pnas.0604248103

Cell Biology

Select this article
Biological Sciences - Cell Biology:
- D. Barcaroli,
- D. Dinsdale,
- M. H. Neale,
- L. Bongiorno-Borbone,
- M. Ranalli,
- E. Munarriz,
- A. E. Sayan,
- J. M. McWilliam,
- T. M. Smith,
- E. Fava,
- R. A. Knight,
- G. Melino,
- and V. De Laurenzi
FLASH is an essential component of Cajal bodies
PNAS 2006 103:14802-14807; published ahead of print September 26, 2006, doi:10.1073/pnas.0604225103
Open Access Article
Select this article
Biological Sciences - Cell Biology:
- D. Barcaroli,
- L. Bongiorno-Borbone,
- A. Terrinoni,
- T. G. Hofmann,
- M. Rossi,
- R. A. Knight,
- A. G. Matera,
- G. Melino,
- and V. De Laurenzi
FLASH is required for histone transcription and S-phase progression
PNAS 2006 103:14808-14812; published ahead of print September 26, 2006, doi:10.1073/pnas.0604227103
Open Access Article
Select this article
Biological Sciences - Cell Biology:
- Andras Perl,
- Yueming Qian,
- Kazim R. Chohan,
- Cynthia R. Shirley,
- Wendy Amidon,
- Sanjay Banerjee,
- Frank A. Middleton,
- Karina L. Conkrite,
- Maureen Barcza,
- Nick Gonchoroff,
- Susan S. Suarez,

FROM THE COVER

In This Issue

Monoclonal antibodies from plants: A new speed record

Encapsulation of a reactive core in neuromelanin

Tumors reveal their secrets to cytotoxic T cells

Imatinib spells BAD news for Bcr/abl-positive leukemias

Reconstruction of New Orleans after Hurricane Katrina: A research perspective

Profile of Daniel J. Cosgrove

Colloquium Papers: Characterization and prediction of protein–protein interactions within and between complexes

Colloquium Papers: Genomic analysis of the hierarchical structure of regulatory networks

Recruitment of dynein to the Jurkat immunological synapse

Prediction of protein orientation upon immobilization on biological and nonbiological surfaces

Templated biomineralization on self-assembled protein fibers

A Trojan horse transition state analogue generated by MgF 3 − formation in an enzyme active site

From the Cover: Identification of class I MHC-associated phosphopeptides as targets for cancer immunotherapy

A hypothesis for vulnerable plaque rupture due to stress-induced debonding around cellular microcalcifications in thin fibrous caps

Biological formation of ethane and propane in the deep marine subsurface

From the Cover: A theory for the atmospheric energy spectrum: Depth-limited temperature anomalies at the tropopause

The ferroelectric and cubic phases in BaTiO 3 ferroelectrics are also antiferroelectric

Deterministic hydrodynamics: Taking blood apart

When motion appears stopped: Stereo motion standstill

From the Cover: Rapid high-yield expression of full-size IgG antibodies in plants coinfected with noncompeting viral vectors

Calcium-sensitive MRI contrast agents based on superparamagnetic iron oxide nanoparticles and calmodulin

Culling and cattle controls influence tuberculosis risk for badgers

Colloquium Papers: Characterization and prediction of protein–protein interactions within and between complexes

Colloquium Papers: Genomic analysis of the hierarchical structure of regulatory networks

A Trojan horse transition state analogue generated by MgF 3 − formation in an enzyme active site

Direct spectroscopic detection of a C-H-cleaving high-spin Fe(IV) complex in a prolyl-4-hydroxylase

Structural and mutational studies of the amino acid-editing domain from archaeal/eukaryal phenylalanyl-tRNA synthetase

Detoxification of superoxide without production of H 2 O 2 : Antioxidant activity of superoxide reductase complexed with ferrocyanide

Preferential transfer of the complete glycan is determined by the oligosaccharyltransferase complex and not by the catalytic subunit

Asymmetric phospholipid distribution drives in vitro reconstituted SNARE-dependent membrane fusion

Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

Prediction of protein orientation upon immobilization on biological and nonbiological surfaces

Deterministic hydrodynamics: Taking blood apart

From the Cover: The surface oxidation potential of human neuromelanin reveals a spherical architecture with a pheomelanin core and a eumelanin surface

Measurement of the mechanical properties of isolated tectorial membrane using atomic force microscopy

Two ligand-binding sites in the O 2 -sensing signal transducer HemAT: Implications for ligand recognition/discrimination and signaling

FLASH is an essential component of Cajal bodies

FLASH is required for histone transcription and S-phase progression