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THIS WEEK IN PNAS

In This Issue
PNAS 2007 104: 3669-3670. [Full Text] [PDF]  

COMMENTARIES

Stephen J. Novak

The role of evolution in the invasion process
PNAS 2007 104: 3671-3672; published online before print February 28 2007, 10.1073/pnas.0700224104 [Extract] [Full Text] [PDF]  
See companion article on page 3883

R. Scott Hawley

Meiosis in living color: Fluorescence-based tetrad analysis in Arabidopsis
PNAS 2007 104: 3673-3674; published online before print February 28 2007, 10.1073/pnas.0700276104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 3913

Dean DellaPenna

Biofortification of plant-based food: Enhancing folate levels by metabolic engineering
PNAS 2007 104: 3675-3676; published online before print March 5 2007, 10.1073/pnas.0700640104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 4218

PHYSICAL SCIENCES

Applied Mathematics

Applied Physical Sciences

Chemistry

Yang Xu, Mark S. Hixon, Noboru Yamamoto, Laura A. McAllister, Anita D. Wentworth, Paul Wentworth, Jr., and Kim D. Janda

Antibody-catalyzed anaerobic destruction of methamphetamine
PNAS 2007 104: 3681-3686; published online before print February 28 2007, 10.1073/pnas.0611094104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Jingyuan Li, Xiaojing Gong, Hangjun Lu, Ding Li, Haiping Fang, and Ruhong Zhou

Electrostatic gating of a nanometer water channel
PNAS 2007 104: 3687-3692; published online before print February 27 2007, 10.1073/pnas.0604541104 [Abstract] [Full Text] [Figures Only] [PDF]  

Christina T. Hauser and Roger Y. Tsien A hexahistidine-Zn2+-dye label reveals STIM1 surface exposure PNAS 2007 104: 3693-3697; published online before print February 28 2007, 10.1073/pnas.0611713104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Ben-Zhan Zhu, Hong-Tao Zhao, Balaraman Kalyanaraman, Jun Liu, Guo-Qiang Shan, Yu-Guo Du, and Balz Frei

Mechanism of metal-independent decomposition of organic hydroperoxides and formation of alkoxyl radicals by halogenated quinones
PNAS 2007 104: 3698-3702; published online before print February 28 2007, 10.1073/pnas.0605527104 [Abstract] [Full Text] [Figures Only] [PDF]  

G. K. Surya Prakash, Thomas Mathew, Chiradeep Panja, Steevens Alconcel, Habiba Vaghoo, Clement Do, and George A. Olah

Gallium (III) triflate catalyzed efficient Strecker reaction of ketones and their fluorinated analogs
PNAS 2007 104: 3703-3706; published online before print February 28 2007, 10.1073/pnas.0611316104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Zhi-Yong Yang, Hui-Min Zhang, Cun-Ji Yan, Shan-Shan Li, Hui-Juan Yan, Wei-Guo Song, and Li-Jun Wan

Scanning tunneling microscopy of the formation, transformation, and property of oligothiophene self-organizations on graphite and gold surfaces
PNAS 2007 104: 3707-3712; published online before print February 28 2007, 10.1073/pnas.0611585104 [Abstract] [Full Text] [Figures Only] [PDF]  

Environmental Sciences

Geophysics

Mathematics

Kathrin Bringmann and Ken Ono

Lifting cusp forms to Maass forms with an application to partitions
PNAS 2007 104: 3725-3731; published online before print February 28 2007, 10.1073/pnas.0611414104 [Abstract] [Full Text] [PDF]  

Physics

Xiao-Jia Chen, Viktor V. Struzhkin, Zhigang Wu, Hai-Qing Lin, Russell J. Hemley, and Ho-kwang Mao

Unified picture of the oxygen isotope effect in cuprate superconductors
PNAS 2007 104: 3732-3735; published online before print February 26 2007, 10.1073/pnas.0611473104 [Abstract] [Full Text] [Figures Only] [PDF]  

Lars Hufnagel, Aurelio A. Teleman, Hervé Rouault, Stephen M. Cohen, and Boris I. Shraiman

On the mechanism of wing size determination in fly development
PNAS 2007 104: 3835-3840; published online before print February 28 2007, 10.1073/pnas.0607134104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

BIOLOGICAL SCIENCES

Anthropology

J. Burger, M. Kirchner, B. Bramanti, W. Haak, and M. G. Thomas

Absence of the lactase-persistence-associated allele in early Neolithic Europeans
PNAS 2007 104: 3736-3741; published online before print February 28 2007, 10.1073/pnas.0607187104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  

Applied Biological Sciences

Hua Shi, Xiaochun Fan, Aarti Sevilimedu, and John T. Lis

RNA aptamers directed to discrete functional sites on a single protein structural domain
PNAS 2007 104: 3742-3746; published online before print February 28 2007, 10.1073/pnas.0607805104 [Abstract] [Full Text] [Figures Only] [PDF]  

Michael Newcomb, Chun-Yu Chen, and J. H. David Wu

Induction of the celC operon of Clostridium thermocellum by laminaribiose
PNAS 2007 104: 3747-3752; published online before print February 27 2007, 10.1073/pnas.0700087104 [Abstract] [Full Text] [Figures Only] [PDF]  

Biochemistry

Yang Xu, Mark S. Hixon, Noboru Yamamoto, Laura A. McAllister, Anita D. Wentworth, Paul Wentworth, Jr., and Kim D. Janda

Antibody-catalyzed anaerobic destruction of methamphetamine
PNAS 2007 104: 3681-3686; published online before print February 28 2007, 10.1073/pnas.0611094104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Kengo Okamoto and Noriyuki Sagata

Mechanism for inactivation of the mitotic inhibitory kinase Wee1 at M phase
PNAS 2007 104: 3753-3758; published online before print February 23 2007, 10.1073/pnas.0607357104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Takanori Muto, Daisuke Tsuchiya, Kosuke Morikawa, and Hisato Jingami

Structures of the extracellular regions of the group II/III metabotropic glutamate receptors
PNAS 2007 104: 3759-3764; published online before print February 26 2007, 10.1073/pnas.0611577104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Felicitas Berger, Corinna Lau, and Mathias Ziegler

Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1
PNAS 2007 104: 3765-3770; published online before print February 22 2007, 10.1073/pnas.0609211104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Brent O. Cezairliyan and Robert T. Sauer

Inhibition of regulated proteolysis by RseB
PNAS 2007 104: 3771-3776; published online before print February 26 2007, 10.1073/pnas.0611567104 [Abstract] [Full Text] [Figures Only] [PDF]  

Biophysics

Jingyuan Li, Xiaojing Gong, Hangjun Lu, Ding Li, Haiping Fang, and Ruhong Zhou

Electrostatic gating of a nanometer water channel
PNAS 2007 104: 3687-3692; published online before print February 27 2007, 10.1073/pnas.0604541104 [Abstract] [Full Text] [Figures Only] [PDF]  

Peijun Zhang, Cezar M. Khursigara, Lisa M. Hartnell, and Sriram Subramaniam

Direct visualization of Escherichia coli chemotaxis receptor arrays using cryo-electron microscopy
PNAS 2007 104: 3777-3781; published online before print February 26 2007, 10.1073/pnas.0610106104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Qi Lin, Delphine Gourdon, Chengjun Sun, Niels Holten-Andersen, Travers H. Anderson, J. Herbert Waite, and Jacob N. Israelachvili

Adhesion mechanisms of the mussel foot proteins mfp-1 and mfp-3
PNAS 2007 104: 3782-3786; published online before print February 28 2007, 10.1073/pnas.0607852104 [Abstract] [Full Text] [Figures Only] [PDF]  

Cell Biology

Tobias Schmelzle, Arnaud A. Mailleux, Michael Overholtzer, Jason S. Carroll, Nicole L. Solimini, Eric S. Lightcap, Ole P. Veiby, and Joan S. Brugge

Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis
PNAS 2007 104: 3787-3792; published online before print February 26 2007, 10.1073/pnas.0700115104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Roberto Zoncu, Rushika M. Perera, Rafael Sebastian, Fubito Nakatsu, Hong Chen, Tamas Balla, Guillermo Ayala, Derek Toomre, and Pietro V. De Camilli Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate PNAS 2007 104: 3793-3798; published online before print February 27 2007, 10.1073/pnas.0611733104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Kazuhiro Sugihara, Daijiro Sugiyama, James Byrne, Don P. Wolf, Kevin P. Lowitz, Yoichi Kobayashi, Maryam Kabir-Salmani, Daita Nadano, Daisuke Aoki, Shiro Nozawa, Jun Nakayama, Tomas Mustelin, Erkki Ruoslahti, Naoto Yamaguchi, and Michiko N. Fukuda Trophoblast cell activation by trophinin ligation is implicated in human embryo implantation PNAS 2007 104: 3799-3804; published online before print February 26 2007, 10.1073/pnas.0611516104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures] OPEN ACCESS ARTICLE

Kathrin Zaugg, Yu-Wen Su, Patrick T. Reilly, Yasmin Moolani, Carol C. Cheung, Razquallah Hakem, Atsushi Hirao, Quinghua Liu, Stephen J. Elledge, and Tak W. Mak

Cross-talk between Chk1 and Chk2 in double-mutant thymocytes
PNAS 2007 104: 3805-3810; published online before print February 26 2007, 10.1073/pnas.0611584104 [Abstract] [Full Text] [Figures Only] [PDF]  

Joseph S. Glavy, Andrew N. Krutchinsky, Ileana M. Cristea, Ian C. Berke, Thomas Boehmer, Günter Blobel, and Brian T. Chait

Cell-cycle-dependent phosphorylation of the nuclear pore Nup107–160 subcomplex
PNAS 2007 104: 3811-3816; published online before print February 28 2007, 10.1073/pnas.0700058104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Shiyu Wang, Savitha Narendra, and Nina Fedoroff

Heterotrimeric G protein signaling in the Arabidopsis unfolded protein response
PNAS 2007 104: 3817-3822; published online before print February 28 2007, 10.1073/pnas.0611735104 [Abstract] [Full Text] [Figures Only] [PDF]  

Sang-Won Min, Wen-Pin Chang, and Thomas C. Südhof

E-Syts, a family of membranous Ca²⁺-sensor proteins with multiple C₂ domains
PNAS 2007 104: 3823-3828; published online before print February 28 2007, 10.1073/pnas.0611725104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jordane Malaterre, Marina Carpinelli, Matthias Ernst, Warren Alexander, Michael Cooke, Susan Sutton, Sebastian Dworkin, Joan K. Heath, Jon Frampton, Grant McArthur, Hans Clevers, Douglas Hilton, Theo Mantamadiotis, and Robert G. Ramsay

c-Myb is required for progenitor cell homeostasis in colonic crypts
PNAS 2007 104: 3829-3834; published online before print February 26 2007, 10.1073/pnas.0610055104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Developmental Biology

Lars Hufnagel, Aurelio A. Teleman, Hervé Rouault, Stephen M. Cohen, and Boris I. Shraiman

On the mechanism of wing size determination in fly development
PNAS 2007 104: 3835-3840; published online before print February 28 2007, 10.1073/pnas.0607134104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Weiliang Xia, Dolores D. Mruk, and C. Yan Cheng

C-type natriuretic peptide regulates blood–testis barrier dynamics in adult rat testes
PNAS 2007 104: 3841-3846; published online before print February 27 2007, 10.1073/pnas.0610100104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Guoyan Zhao, Grace Boekhoff-Falk, Beth A. Wilson, and James B. Skeath

Linking pattern formation to cell-type specification: Dichaete and Ind directly repress achaete gene expression in the Drosophila CNS
PNAS 2007 104: 3847-3852; published online before print February 26 2007, 10.1073/pnas.0611700104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Isabella Artner, Bruno Blanchi, Jeffrey C. Raum, Min Guo, Tomomi Kaneko, Sabine Cordes, Michael Sieweke, and Roland Stein MafB is required for islet cell maturation PNAS 2007 104: 3853-3858; published online before print February 22 2007, 10.1073/pnas.0700013104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures] OPEN ACCESS ARTICLE

Yu Liu, Masanori Asakura, Hironori Inoue, Teruya Nakamura, Motoaki Sano, Zhiyv Niu, Michelle Chen, Robert J. Schwartz, and Michael D. Schneider

Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells
PNAS 2007 104: 3859-3864; published online before print February 28 2007, 10.1073/pnas.0609100104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Masaru Matsuda, Ai Shinomiya, Masato Kinoshita, Aya Suzuki, Tohru Kobayashi, Bindhu Paul-Prasanth, En-lieng Lau, Satoshi Hamaguchi, Mitsuru Sakaizumi, and Yoshitaka Nagahama

DMY gene induces male development in genetically female (XX) medaka fish
PNAS 2007 104: 3865-3870; published online before print February 28 2007, 10.1073/pnas.0611707104 [Abstract] [Full Text] [Figures Only] [PDF]  

Corinne A. Boulanger, David L. Mack, Brian W. Booth, and Gilbert H. Smith

Interaction with the mammary microenvironment redirects spermatogenic cell fate in vivo
PNAS 2007 104: 3871-3876; published online before print February 28 2007, 10.1073/pnas.0611637104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Barbara J. Muller-Borer, Wayne E. Cascio, Gwyn L. Esch, Hyung-Suk Kim, William B. Coleman, Joe W. Grisham, Page A. W. Anderson, and Nadia N. Malouf Mechanisms controlling the acquisition of a cardiac phenotype by liver stem cells PNAS 2007 104: 3877-3882; published online before print February 26 2007, 10.1073/pnas.0700416104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Ecology

Sébastien Lavergne and Jane Molofsky From the Cover: Increased genetic variation and evolutionary potential drive the success of an invasive grass PNAS 2007 104: 3883-3888; published online before print February 28 2007, 10.1073/pnas.0607324104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE   See Commentary on page 3671

L. F. Sundström, M. Lõhmus, W. E. Tymchuk, and Robert H. Devlin

Gene–environment interactions influence ecological consequences of transgenic animals
PNAS 2007 104: 3889-3894; published online before print February 27 2007, 10.1073/pnas.0608767104 [Abstract] [Full Text] [Figures Only] [PDF]  

Environmental Sciences

Patricia Ortiz-Bermúdez, Kolby C. Hirth, Ewald Srebotnik, and Kenneth E. Hammel

Chlorination of lignin by ubiquitous fungi has a likely role in global organochlorine production
PNAS 2007 104: 3895-3900; published online before print February 26 2007, 10.1073/pnas.0610074104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Evolution

Jun Gojobori, Hua Tang, Joshua M. Akey, and Chung-I Wu

Adaptive evolution in humans revealed by the negative correlation between the polymorphism and fixation phases of evolution
PNAS 2007 104: 3907-3912; published online before print February 26 2007, 10.1073/pnas.0605565104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Genetics

Xianghua Zhou, Fei Tian, Johan Sandzén, Renhai Cao, Emilie Flaberg, Laszlo Szekely, Yihai Cao, Claes Ohlsson, Martin O. Bergo, Jan Borén, and Levent M. Akyürek

Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development
PNAS 2007 104: 3919-3924; published online before print February 26 2007, 10.1073/pnas.0608360104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Karen W. Y. Yuen, Cheryl D. Warren, Ou Chen, Teresa Kwok, Phil Hieter, and Forrest A. Spencer

Systematic genome instability screens in yeast and their potential relevance to cancer
PNAS 2007 104: 3925-3930; published online before print February 28 2007, 10.1073/pnas.0610642104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Christine M. Khoo, Daniel R. Carrasco, Marcus W. Bosenberg, Ji-Hye Paik, and Ronald A. DePinho

Ink4a/Arf tumor suppressor does not modulate the degenerative conditions or tumor spectrum of the telomerase-deficient mouse
PNAS 2007 104: 3931-3936; published online before print February 27 2007, 10.1073/pnas.0700093104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Veraragavan P. Eswarakumar and Joseph Schlessinger

Skeletal overgrowth is mediated by deficiency in a specific isoform of fibroblast growth factor receptor 3
PNAS 2007 104: 3937-3942; published online before print February 23 2007, 10.1073/pnas.0700012104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Karen Ocorr, Nick L. Reeves, Robert J. Wessells, Martin Fink, H.-S. Vincent Chen, Takeshi Akasaka, Soichiro Yasuda, Joseph M. Metzger, Wayne Giles, James W. Posakony, and Rolf Bodmer

KCNQ potassium channel mutations cause cardiac arrhythmias in Drosophila that mimic the effects of aging
PNAS 2007 104: 3943-3948; published online before print February 28 2007, 10.1073/pnas.0609278104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Rami I. Aqeilan, Francesco Trapasso, Sadiq Hussain, Stefan Costinean, Dean Marshall, Yuri Pekarsky, John P. Hagan, Nicola Zanesi, Mohamed Kaou, Gary S. Stein, Jane B. Lian, and Carlo M. Croce

Targeted deletion of Wwox reveals a tumor suppressor function
PNAS 2007 104: 3949-3954; published online before print February 27 2007, 10.1073/pnas.0609783104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Piotr A. Mieczkowski, Margaret Dominska, Michael J. Buck, Jason D. Lieb, and Thomas D. Petes Loss of a histone deacetylase dramatically alters the genomic distribution of Spo11p-catalyzed DNA breaks in Saccharomyces cerevisiae PNAS 2007 104: 3955-3960; published online before print February 28 2007, 10.1073/pnas.0700412104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Hui Wu, Susan A. Boackle, Punchong Hanvivadhanakul, Daniela Ulgiati, Jennifer M. Grossman, Youngho Lee, Nan Shen, Lawrence J. Abraham, Timothy R. Mercer, Elly Park, Lee A. Hebert, Brad H. Rovin, Dan J. Birmingham, Deh-Ming Chang, Chung Jen Chen, Deborah McCurdy, Humeira M. Badsha, Bernard Y. H. Thong, Hiok H. Chng, Frank C. Arnett, Daniel J. Wallace, C. Yung Yu, Bevra H. Hahn, Rita M. Cantor, and Betty P. Tsao

Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus
PNAS 2007 104: 3961-3966; published online before print February 22 2007, 10.1073/pnas.0609101104 [Abstract] [Full Text] [Figures Only] [PDF]  

Immunology

Padmanee Sharma, Yu Shen, Sijin Wen, Sachiko Yamada, Achim A. Jungbluth, Sacha Gnjatic, Dean F. Bajorin, Victor E. Reuter, Harry Herr, Lloyd J. Old, and Eiichi Sato

CD8 tumor-infiltrating lymphocytes are predictive of survival in muscle-invasive urothelial carcinoma
PNAS 2007 104: 3967-3972; published online before print February 27 2007, 10.1073/pnas.0611618104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]  

Freeman Suber, Michael C. Carroll, and Francis D. Moore, Jr.

Innate response to self-antigen significantly exacerbates burn wound depth
PNAS 2007 104: 3973-3977; published online before print February 28 2007, 10.1073/pnas.0609026104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Jonathan Back, Anick Chalifour, Léonardo Scarpellino, and Werner Held

Stable masking by H-2D^d cis ligand limits Ly49A relocalization to the site of NK cell/target cell contact
PNAS 2007 104: 3978-3983; published online before print February 26 2007, 10.1073/pnas.0607418104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Grazia Galli, Paola Pittoni, Elena Tonti, Carmine Malzone, Yasushi Uematsu, Marco Tortoli, Domenico Maione, Gianfranco Volpini, Oretta Finco, Sandra Nuti, Simona Tavarini, Paolo Dellabona, Rino Rappuoli, Giulia Casorati, and Sergio Abrignani Invariant NKT cells sustain specific B cell responses and memory PNAS 2007 104: 3984-3989; published online before print February 27 2007, 10.1073/pnas.0700191104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Christina C. N. Wu, Tomoko Hayashi, Kenji Takabayashi, Mojgan Sabet, Donald F. Smee, Donald D. Guiney, Howard B. Cottam, and Dennis A. Carson

Immunotherapeutic activity of a conjugate of a Toll-like receptor 7 ligand
PNAS 2007 104: 3990-3995; published online before print February 21 2007, 10.1073/pnas.0611624104 [Abstract] [Full Text] [Figures Only] [PDF]  

Irma Airoldi, Emma Di Carlo, Claudia Cocco, Giuseppe Taverniti, Tommaso D'Antuono, Emanuela Ognio, Morihiro Watanabe, Domenico Ribatti, and Vito Pistoia From the Cover: Endogenous IL-12 triggers an antiangiogenic program in melanoma cells PNAS 2007 104: 3996-4001; published online before print February 23 2007, 10.1073/pnas.0609028104 [Abstract] [Full Text] [Figures Only] [PDF]

Cherry Wu, Sheila Ranganath, Megan Gleason, Barbara B. Woodman, Tiffany M. Borjeson, Frederick W. Alt, and Craig H. Bassing

Restriction of endogenous T cell antigen receptor rearrangements to V14 through selective recombination signal sequence modifications
PNAS 2007 104: 4002-4007; published online before print February 27 2007, 10.1073/pnas.0700081104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Medical Sciences

Albert Cerussi, David Hsiang, Natasha Shah, Rita Mehta, Amanda Durkin, John Butler, and Bruce J. Tromberg Predicting response to breast cancer neoadjuvant chemotherapy using diffuse optical spectroscopy PNAS 2007 104: 4014-4019; published online before print February 28 2007, 10.1073/pnas.0611058104 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Aaron M. Ring, Sam X. Cheng, Qiang Leng, Kristopher T. Kahle, Jesse Rinehart, Maria D. Lalioti, Heather M. Volkman, Frederick H. Wilson, Steven C. Hebert, and Richard P. Lifton WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo PNAS 2007 104: 4020-4024; published online before print February 26 2007, 10.1073/pnas.0611727104 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Aaron M. Ring, Qiang Leng, Jesse Rinehart, Frederick H. Wilson, Kristopher T. Kahle, Steven C. Hebert, and Richard P. Lifton An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis PNAS 2007 104: 4025-4029; published online before print February 22 2007, 10.1073/pnas.0611728104 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Mineko Fujimiya, Hideto Kojima, Masumi Ichinose, Ryohachi Arai, Hiroshi Kimura, Atsunori Kashiwagi, and Lawrence Chan

Fusion of proinsulin-producing bone marrow-derived cells with hepatocytes in diabetes
PNAS 2007 104: 4030-4035; published online before print February 27 2007, 10.1073/pnas.0700220104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

James M. Amos-Landgraf, Lawrence N. Kwong, Christina M. Kendziorski, Mark Reichelderfer, Jose Torrealba, Jamey Weichert, Jill D. Haag, Kai-Shun Chen, Jordy L. Waller, Michael N. Gould, and William F. Dove A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer PNAS 2007 104: 4036-4041; published online before print February 27 2007, 10.1073/pnas.0611690104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Jakub Hort, Jan Laczó, Martin Vyhnálek, Martin Bojar, Jan Bures, and Kamil Vlcek

Spatial navigation deficit in amnestic mild cognitive impairment
PNAS 2007 104: 4042-4047; published online before print February 28 2007, 10.1073/pnas.0611314104 [Abstract] [Full Text] [Figures Only] [PDF]  

Craig D. Peacock, Qiuju Wang, Gregory S. Gesell, Ian M. Corcoran-Schwartz, Evan Jones, Jynho Kim, Wendy L. Devereux, Jonathan T. Rhodes, Carol A. Huff, Philip A. Beachy, D. Neil Watkins, and William Matsui Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma PNAS 2007 104: 4048-4053; published online before print February 27 2007, 10.1073/pnas.0611682104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Peng Wang, Jian Yu, and Lin Zhang

The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage
PNAS 2007 104: 4054-4059; published online before print February 28 2007, 10.1073/pnas.0700020104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Xiaodong Zhang, Ailan Guo, Jianshi Yu, Anthony Possemato, Yueting Chen, Weiping Zheng, Roberto D. Polakiewicz, Kenneth W. Kinzler, Bert Vogelstein, Victor E. Velculescu, and Zhenghe John Wang Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T PNAS 2007 104: 4060-4064; published online before print February 21 2007, 10.1073/pnas.0611665104 [Abstract] [Full Text] [Figures Only] [PDF] OPEN ACCESS ARTICLE

Hui Joyce Li, Zaffar Haque, Qing Lu, Li Li, Richard Karas, and Michael Mendelsohn

Steroid receptor coactivator 3 is a coactivator for myocardin, the regulator of smooth muscle transcription and differentiation
PNAS 2007 104: 4065-4070; published online before print February 28 2007, 10.1073/pnas.0611639104 [Abstract] [Full Text] [Figures Only] [PDF]  

Andrew M. Scott, Fook-Thean Lee, Niall Tebbutt, Rebecca Herbertson, Sanjeev S. Gill, Zhanqi Liu, Effie Skrinos, Carmel Murone, Timothy H. Saunder, Bridget Chappell, Anthony T. Papenfuss, Aurora M. T. Poon, Wendie Hopkins, Fiona E. Smyth, Duncan MacGregor, Lawrence M. Cher, Achim A. Jungbluth, Gerd Ritter, Martin W. Brechbiel, Roger Murphy, Antony W. Burgess, Eric W. Hoffman, Terrance G. Johns, and Lloyd J. Old A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors PNAS 2007 104: 4071-4076; published online before print February 28 2007, 10.1073/pnas.0611693104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Wei-Jian Zhang, Hao Wei, Tory Hagen, and Balz Frei -Lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway PNAS 2007 104: 4077-4082; published online before print February 27 2007, 10.1073/pnas.0700305104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

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Microbiology