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THIS WEEK IN PNAS

In This Issue
PNAS 2007 104: 5253-5254. [Full Text] [PDF]  

COMMENTARIES

John A. Hammer, III and Xufeng Wu

Slip sliding away with myosin V
PNAS 2007 104: 5255-5256; published online before print March 20 2007, 10.1073/pnas.0701071104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 4332 in issue 11 of volume 104

Jonathan Gershenzon

Plant volatiles carry both public and private messages
PNAS 2007 104: 5257-5258; published online before print March 22 2007, 10.1073/pnas.0700906104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 5467

Michael P. Lesser

Coral reef bleaching and global climate change: Can corals survive the next century?
PNAS 2007 104: 5259-5260; published online before print March 20 2007, 10.1073/pnas.0700910104 [Extract] [Full Text] [Figures Only] [PDF]  
See companion article on page 5483

PHYSICAL SCIENCES

Chemistry

Young Min Rhee, Timothy J. Lee, Murthy S. Gudipati, Louis J. Allamandola, and Martin Head-Gordon From the Cover: Charged polycyclic aromatic hydrocarbon clusters and the galactic extended red emission PNAS 2007 104: 5274-5278; published online before print March 19 2007, 10.1073/pnas.0609396104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]

Agustin Schiffrin, Andreas Riemann, Willi Auwärter, Yan Pennec, Alex Weber-Bargioni, Dean Cvetko, Albano Cossaro, Alberto Morgante, and Johannes V. Barth

Zwitterionic self-assembly of L-methionine nanogratings on the Ag(111) surface
PNAS 2007 104: 5279-5284; published online before print March 19 2007, 10.1073/pnas.0607867104 [Abstract] [Full Text] [Figures Only] [PDF]  

Satoshi Takeuchi and Tahei Tahara

The answer to concerted versus step-wise controversy for the double proton transfer mechanism of 7-azaindole dimer in solution
PNAS 2007 104: 5285-5290; published online before print March 20 2007, 10.1073/pnas.0610141104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Roberto J. Brea, Luis Castedo, Juan R. Granja, M. Ángeles Herranz, Luis Sánchez, Nazario Martín, Wolfgang Seitz, and Dirk M. Guldi

Electron transfer in Me-blocked heterodimeric ,-peptide nanotubular donor–acceptor hybrids
PNAS 2007 104: 5291-5294; published online before print March 19 2007, 10.1073/pnas.0609506104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Weihong Qiu, Lijuan Wang, Wenyun Lu, Amanda Boechler, David A. R. Sanders, and Dongping Zhong

Dissection of complex protein dynamics in human thioredoxin
PNAS 2007 104: 5366-5371; published online before print March 16 2007, 10.1073/pnas.0608498104 [Abstract] [Full Text] [Figures Only] [PDF]  

Dennis C. Wylie, Jayajit Das, and Arup K. Chakraborty

Sensitivity of T cells to antigen and antagonism emerges from differential regulation of the same molecular signaling module
PNAS 2007 104: 5533-5538; published online before print March 2 2007, 10.1073/pnas.0611482104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Environmental Sciences

Geology

Geophysics

Physics

M. Cosentino Lagomarsino, P. Jona, B. Bassetti, and H. Isambert

Hierarchy and feedback in the evolution of the Escherichia coli transcription network
PNAS 2007 104: 5516-5520; published online before print March 19 2007, 10.1073/pnas.0609023104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Appendix]  

BIOLOGICAL SCIENCES

Applied Biological Sciences

Biochemistry

Donald E. Johnson, Masateru Takahashi, Samir M. Hamdan, Seung-Joo Lee, and Charles C. Richardson

Exchange of DNA polymerases at the replication fork of bacteriophage T7
PNAS 2007 104: 5312-5317; published online before print March 16 2007, 10.1073/pnas.0701062104 [Abstract] [Full Text] [Figures Only] [PDF]  

Sandra E. Wiley, Anne N. Murphy, Stuart A. Ross, Peter van der Geer, and Jack E. Dixon

MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity
PNAS 2007 104: 5318-5323; published online before print March 21 2007, 10.1073/pnas.0701078104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Guoliang Qing, Zhaoxia Qu, and Gutian Xiao

Endoproteolytic processing of C-terminally truncated NF-B2 precursors at B-containing promoters
PNAS 2007 104: 5324-5329; published online before print March 15 2007, 10.1073/pnas.0609914104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Sen Liu, Shiyong Liu, Xiaolei Zhu, Huanhuan Liang, Aoneng Cao, Zhijie Chang, and Luhua Lai

Nonnatural protein–protein interaction-pair design by key residues grafting
PNAS 2007 104: 5330-5335; published online before print March 19 2007, 10.1073/pnas.0606198104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

David N. Bolam, Shirley Roberts, Mark R. Proctor, Johan P. Turkenburg, Eleanor J. Dodson, Carlos Martinez-Fleites, Min Yang, Benjamin G. Davis, Gideon J. Davies, and Harry J. Gilbert

The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity
PNAS 2007 104: 5336-5341; published online before print March 21 2007, 10.1073/pnas.0607897104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

George W. Farr, Wayne A. Fenton, and Arthur L. Horwich Perturbed ATPase activity and not "close confinement" of substrate in the cis cavity affects rates of folding by tail-multiplied GroEL PNAS 2007 104: 5342-5347; published online before print March 19 2007, 10.1073/pnas.0700820104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Yanqiu Yuan, Dianah Barrett, Yi Zhang, Daniel Kahne, Piotr Sliz, and Suzanne Walker Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis PNAS 2007 104: 5348-5353; published online before print March 8 2007, 10.1073/pnas.0701160104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Elena Santillana, Alejandro Beceiro, Germán Bou, and Antonio Romero

Crystal structure of the carbapenemase OXA-24 reveals insights into the mechanism of carbapenem hydrolysis
PNAS 2007 104: 5354-5359; published online before print March 20 2007, 10.1073/pnas.0607557104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

David C. Hyatt, Buhyun Youn, Yuxin Zhao, Bindu Santhamma, Robert M. Coates, Rodney B. Croteau, and ChulHee Kang

Structure of limonene synthase, a simple model for terpenoid cyclase catalysis
PNAS 2007 104: 5360-5365; published online before print March 19 2007, 10.1073/pnas.0700915104 [Abstract] [Full Text] [Figures Only] [PDF]  

Biophysics

Weihong Qiu, Lijuan Wang, Wenyun Lu, Amanda Boechler, David A. R. Sanders, and Dongping Zhong

Dissection of complex protein dynamics in human thioredoxin
PNAS 2007 104: 5366-5371; published online before print March 16 2007, 10.1073/pnas.0608498104 [Abstract] [Full Text] [Figures Only] [PDF]  

Md Rejwan Ali, Kwan Hon Cheng, and Juyang Huang

Assess the nature of cholesterol–lipid interactions through the chemical potential of cholesterol in phosphatidylcholine bilayers
PNAS 2007 104: 5372-5377; published online before print March 19 2007, 10.1073/pnas.0611450104 [Abstract] [Full Text] [Figures Only] [PDF]  

Comert Kural, Anna S. Serpinskaya, Ying-Hao Chou, Robert D. Goldman, Vladimir I. Gelfand, and Paul R. Selvin

Tracking melanosomes inside a cell to study molecular motors and their interaction
PNAS 2007 104: 5378-5382; published online before print March 16 2007, 10.1073/pnas.0700145104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Janne A. Ihalainen, Jens Bredenbeck, Rolf Pfister, Jan Helbing, Lei Chi, Ivo H. M. van Stokkum, G. Andrew Woolley, and Peter Hamm

Folding and unfolding of a photoswitchable peptide from picoseconds to microseconds
PNAS 2007 104: 5383-5388; published online before print March 19 2007, 10.1073/pnas.0607748104 [Abstract] [Full Text] [Figures Only] [PDF]  

Cell Biology

Chunhua Shi, Susan Kaminskyj, Sarah Caldwell, and Michèle C. Loewen

A role for a complex between activated G protein-coupled receptors in yeast cellular mating
PNAS 2007 104: 5395-5400; published online before print March 16 2007, 10.1073/pnas.0608219104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Rubaiyat Rahman-Roblick, Uwe Johannes Roblick, Ulf Hellman, Paolo Conrotto, Tao Liu, Susanne Becker, Daniel Hirschberg, Hans Jörnvall, Gert Auer, and Klas G. Wiman p53 targets identified by protein expression profiling PNAS 2007 104: 5401-5406; published online before print March 19 2007, 10.1073/pnas.0700794104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Rikke Nielsen, Pierre J. Courtoy, Christian Jacobsen, Geneviève Dom, Wânia Rezende Lima, Michel Jadot, Thomas E. Willnow, Olivier Devuyst, and Erik I. Christensen

Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells
PNAS 2007 104: 5407-5412; published online before print March 16 2007, 10.1073/pnas.0700330104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Amrik J. Singh, Rosana D. Meyer, Gyulmagomed Navruzbekov, Rajani Shelke, Lei Duan, Hamid Band, Susan E. Leeman, and Nader Rahimi A critical role for the E3-ligase activity of c-Cbl in VEGFR-2-mediated PLC1 activation and angiogenesis PNAS 2007 104: 5413-5418; published online before print March 19 2007, 10.1073/pnas.0700809104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures] OPEN ACCESS ARTICLE

A. R. M. Ruhul Amin, Vijay S. Thakur, Rajib K. Paul, Gen Sheng Feng, Cheng-Kui Qu, Hasan Mukhtar, and Munna L. Agarwal

SHP-2 tyrosine phosphatase inhibits p73-dependent apoptosis and expression of a subset of p53 target genes induced by EGCG
PNAS 2007 104: 5419-5424; published online before print March 16 2007, 10.1073/pnas.0700642104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Sangmyung Rhee, Hongmei Jiang, Chin-Han Ho, and Frederick Grinnell

Microtubule function in fibroblast spreading is modulated according to the tension state of cell–matrix interactions
PNAS 2007 104: 5425-5430; published online before print March 16 2007, 10.1073/pnas.0608030104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Movies]  

Kalindi Parmar, Peter Mauch, Jo-Anne Vergilio, Robert Sackstein, and Julian D. Down

Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia
PNAS 2007 104: 5431-5436; published online before print March 20 2007, 10.1073/pnas.0701152104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Liang Song, Meng-Hsuan Han, Joanna Lesicka, and Nina Fedoroff

Arabidopsis primary microRNA processing proteins HYL1 and DCL1 define a nuclear body distinct from the Cajal body
PNAS 2007 104: 5437-5442; published online before print March 16 2007, 10.1073/pnas.0701061104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Noriko Makita, Junichiro Sato, Katsunori Manaka, Yuki Shoji, Atsuro Oishi, Makiko Hashimoto, Toshiro Fujita, and Taroh Iiri

An acquired hypocalciuric hypercalcemia autoantibody induces allosteric transition among active human Ca-sensing receptor conformations
PNAS 2007 104: 5443-5448; published online before print March 19 2007, 10.1073/pnas.0701290104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Developmental Biology

Laura Ciarloni, Sonia Mallepell, and Cathrin Brisken

Amphiregulin is an essential mediator of estrogen receptor function in mammary gland development
PNAS 2007 104: 5455-5460; published online before print March 16 2007, 10.1073/pnas.0611647104 [Abstract] [Full Text] [Figures Only] [PDF]  

Qin Wei, Yikang Rong, and Bruce M. Paterson

Stereotypic founder cell patterning and embryonic muscle formation in Drosophila require nautilus (MyoD) gene function
PNAS 2007 104: 5461-5466; published online before print March 21 2007, 10.1073/pnas.0608739104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Ecology

Elizabeth T. Borer, Parviez R. Hosseini, Eric W. Seabloom, and Andrew P. Dobson

Pathogen-induced reversal of native dominance in a grassland community
PNAS 2007 104: 5473-5478; published online before print March 19 2007, 10.1073/pnas.0608573104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Christopher N. Templeton and Erick Greene

Nuthatches eavesdrop on variations in heterospecific chickadee mobbing alarm calls
PNAS 2007 104: 5479-5482; published online before print March 19 2007, 10.1073/pnas.0605183104 [Abstract] [Full Text] [Figures Only] [PDF]  

Environmental Sciences

Patricia Murray, Scott A. L. Hayward, Gregor G. Govan, Andrew Y. Gracey, and Andrew R. Cossins

An explicit test of the phospholipid saturation hypothesis of acquired cold tolerance in Caenorhabditis elegans
PNAS 2007 104: 5489-5494; published online before print March 16 2007, 10.1073/pnas.0609590104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Evolution

Michael L. Tress, Pier Luigi Martelli, Adam Frankish, Gabrielle A. Reeves, Jan Jaap Wesselink, Corin Yeats, Páll lsólfur Ólason, Mario Albrecht, Hedi Hegyi, Alejandro Giorgetti, Domenico Raimondo, Julien Lagarde, Roman A. Laskowski, Gonzalo López, Michael I. Sadowski, James D. Watson, Piero Fariselli, Ivan Rossi, Alinda Nagy, Wang Kai, Zenia Størling, Massimiliano Orsini, Yassen Assenov, Hagen Blankenburg, Carola Huthmacher, Fidel Ramírez, Andreas Schlicker, France Denoeud, Phil Jones, Samuel Kerrien, Sandra Orchard, Stylianos E. Antonarakis, Alexandre Reymond, Ewan Birney, Søren Brunak, Rita Casadio, Roderic Guigo, Jennifer Harrow, Henning Hermjakob, David T. Jones, Thomas Lengauer, Christine A. Orengo, László Patthy, Janet M. Thornton, Anna Tramontano, and Alfonso Valencia

The implications of alternative splicing in the ENCODE protein complement
PNAS 2007 104: 5495-5500; published online before print March 19 2007, 10.1073/pnas.0700800104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Aaron O'Dea, Jeremy B. C. Jackson, Helena Fortunato, J. Travis Smith, Luis D'Croz, Kenneth G. Johnson, and Jonathan A. Todd From the Cover: Environmental change preceded Caribbean extinction by 2 million years PNAS 2007 104: 5501-5506; published online before print March 16 2007, 10.1073/pnas.0610947104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Table]

Pi-Peng Li, Ke-Qin Gao, Lian-Hai Hou, and Xing Xu

A gliding lizard from the Early Cretaceous of China
PNAS 2007 104: 5507-5509; published online before print March 21 2007, 10.1073/pnas.0609552104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Susanne Cote, Lars Werdelin, Erik R. Seiffert, and John C. Barry

Additional material of the enigmatic Early Miocene mammal Kelba and its relationship to the order Ptolemaiida
PNAS 2007 104: 5510-5515; published online before print March 19 2007, 10.1073/pnas.0700441104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Genetics

M. Cosentino Lagomarsino, P. Jona, B. Bassetti, and H. Isambert

Hierarchy and feedback in the evolution of the Escherichia coli transcription network
PNAS 2007 104: 5516-5520; published online before print March 19 2007, 10.1073/pnas.0609023104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Appendix]  

Amos Tanay, Anne H. O'Donnell, Marc Damelin, and Timothy H. Bestor

Hyperconserved CpG domains underlie Polycomb-binding sites
PNAS 2007 104: 5521-5526; published online before print March 21 2007, 10.1073/pnas.0609746104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Tibor Rauch, Zunde Wang, Xinmin Zhang, Xueyan Zhong, Xiwei Wu, Sean K. Lau, Kemp H. Kernstine, Arthur D. Riggs, and Gerd P. Pfeifer

Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay
PNAS 2007 104: 5527-5532; published online before print March 16 2007, 10.1073/pnas.0701059104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Immunology

Dennis C. Wylie, Jayajit Das, and Arup K. Chakraborty

Sensitivity of T cells to antigen and antagonism emerges from differential regulation of the same molecular signaling module
PNAS 2007 104: 5533-5538; published online before print March 2 2007, 10.1073/pnas.0611482104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Text]  

Sybill Thomas-Ecker, Antje Lindecke, Wolfgang Hatzmann, Christian Kaltschmidt, Kurt S. Zänker, and Thomas Dittmar

Alteration in the gene expression pattern of primary monocytes after adhesion to endothelial cells
PNAS 2007 104: 5539-5544; published online before print March 19 2007, 10.1073/pnas.0700732104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Tables]  

Yves Lepelletier, Salete Smaniotto, Réda Hadj-Slimane, Déa Maria Serra Villa-Verde, Ana Cristina Nogueira, Mireille Dardenne, Olivier Hermine, and Wilson Savino

Control of human thymocyte migration by Neuropilin-1/Semaphorin-3A-mediated interactions
PNAS 2007 104: 5545-5550; published online before print March 16 2007, 10.1073/pnas.0700705104 [Abstract] [Full Text] [Figures Only] [PDF]  

Weiming Yuan, Xiaoyang Qi, Pansy Tsang, Suk-Jo Kang, Petr A. Illarionov, Gurdyal S. Besra, Jenny Gumperz, and Peter Cresswell

Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules
PNAS 2007 104: 5551-5556; published online before print March 19 2007, 10.1073/pnas.0700617104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Michael R. Ardern-Jones, Antony P. Black, Elizabeth A. Bateman, and Graham S. Ogg

Bacterial superantigen facilitates epithelial presentation of allergen to T helper 2 cells
PNAS 2007 104: 5557-5562; published online before print March 19 2007, 10.1073/pnas.0700733104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figures]  

Medical Sciences

R. Mehrian-Shai, C. D. Chen, T. Shi, S. Horvath, S. F. Nelson, J. K. V. Reichardt, and C. L. Sawyers

Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/Akt pathway activation in glioblastoma and prostate cancer
PNAS 2007 104: 5563-5568; published online before print March 19 2007, 10.1073/pnas.0609139104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Marco Gymnopoulos, Marc-André Elsliger, and Peter K. Vogt

Rare cancer-specific mutations in PIK3CA show gain of function
PNAS 2007 104: 5569-5574; published online before print March 21 2007, 10.1073/pnas.0701005104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Nektarios Barabutis, Erasmia Tsellou, Andrew V. Schally, Stavroula Kouloheri, Anastasios Kalofoutis, and Hippokratis Kiaris

Stimulation of proliferation of MCF-7 breast cancer cells by a transfected splice variant of growth hormone-releasing hormone receptor
PNAS 2007 104: 5575-5579; published online before print March 19 2007, 10.1073/pnas.0700407104 [Abstract] [Full Text] [Figures Only] [PDF]  

Mauro T. Marrelli, Chaoyang Li, Jason L. Rasgon, and Marcelo Jacobs-Lorena

Transgenic malaria-resistant mosquitoes have a fitness advantage when feeding on Plasmodium-infected blood
PNAS 2007 104: 5580-5583; published online before print March 19 2007, 10.1073/pnas.0609809104 [Abstract] [Full Text] [Figures Only] [PDF]  

Sunny Abraham, Fang Guo, Lian-Sheng Li, Christoph Rader, Cheng Liu, Carlos F. Barbas, III, Richard A. Lerner, and Subhash C. Sinha

Synthesis of the next-generation therapeutic antibodies that combine cell targeting and antibody-catalyzed prodrug activation
PNAS 2007 104: 5584-5589; published online before print March 19 2007, 10.1073/pnas.0700223104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Microbiology

Roland Brosch, Stephen V. Gordon, Thierry Garnier, Karin Eiglmeier, Wafa Frigui, Philippe Valenti, Sandrine Dos Santos, Stéphanie Duthoy, Céline Lacroix, Carmen Garcia-Pelayo, Jacqueline K. Inwald, Paul Golby, Javier Nuñez Garcia, R. Glyn Hewinson, Marcel A. Behr, Michael A. Quail, Carol Churcher, Bart G. Barrell, Julian Parkhill, and Stewart T. Cole Genome plasticity of BCG and impact on vaccine efficacy PNAS 2007 104: 5596-5601; published online before print March 19 2007, 10.1073/pnas.0700869104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Lu Feng, Wei Wang, Jiansong Cheng, Yi Ren, Guang Zhao, Chunxu Gao, Yun Tang, Xueqian Liu, Weiqing Han, Xia Peng, Rulin Liu, and Lei Wang

Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir
PNAS 2007 104: 5602-5607; published online before print March 19 2007, 10.1073/pnas.0609650104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jue D. Wang, Melanie B. Berkmen, and Alan D. Grossman

Genome-wide coorientation of replication and transcription reduces adverse effects on replication in Bacillus subtilis
PNAS 2007 104: 5608-5613; published online before print March 19 2007, 10.1073/pnas.0608999104 [Abstract] [Full Text] [Figures Only] [PDF]  

Neuroscience

Andreas Keller and Leslie B. Vosshall

Influence of odorant receptor repertoire on odor perception in humans and fruit flies
PNAS 2007 104: 5614-5619; published online before print March 19 2007, 10.1073/pnas.0605321104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Alexander Maier, Nikos K. Logothetis, and David A. Leopold Context-dependent perceptual modulation of single neurons in primate visual cortex PNAS 2007 104: 5620-5625; published online before print March 16 2007, 10.1073/pnas.0608489104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Keita Koizumi, Haruhiro Higashida, Siuk Yoo, Mohamad Saharul Islam, Andrej I. Ivanov, Vicky Guo, Paola Pozzi, Shu-Hua Yu, Alessandra C. Rovescalli, Derek Tang, and Marshall Nirenberg

RNA interference screen to identify genes required for Drosophila embryonic nervous system development
PNAS 2007 104: 5626-5631; published online before print March 21 2007, 10.1073/pnas.0611687104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

K. Touzani, S. V. Puthanveettil, and E. R. Kandel

Consolidation of learning strategies during spatial working memory task requires protein synthesis in the prefrontal cortex
PNAS 2007 104: 5632-5637; published online before print March 16 2007, 10.1073/pnas.0611554104 [Abstract] [Full Text] [Figures Only] [PDF]  

Ana C. Pereira, Dan E. Huddleston, Adam M. Brickman, Alexander A. Sosunov, Rene Hen, Guy M. McKhann, Richard Sloan, Fred H. Gage, Truman R. Brown, and Scott A. Small

An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus
PNAS 2007 104: 5638-5643; published online before print March 20 2007, 10.1073/pnas.0611721104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

William E. DeCoteau, Catherine Thorn, Daniel J. Gibson, Richard Courtemanche, Partha Mitra, Yasuo Kubota, and Ann M. Graybiel

Learning-related coordination of striatal and hippocampal theta rhythms during acquisition of a procedural maze task
PNAS 2007 104: 5644-5649; published online before print March 19 2007, 10.1073/pnas.0700818104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

María de la Paz Fernández, Jessie Chu, Adriana Villella, Nigel Atkinson, Steve A. Kay, and María Fernanda Ceriani

Impaired clock output by altered connectivity in the circadian network
PNAS 2007 104: 5650-5655; published online before print March 16 2007, 10.1073/pnas.0608260104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Marzena J. Fabis, Gwen S. Scott, Rhonda B. Kean, Hilary Koprowski, and D. Craig Hooper

Loss of blood–brain barrier integrity in the spinal cord is common to experimental allergic encephalomyelitis in knockout mouse models
PNAS 2007 104: 5656-5661; published online before print March 19 2007, 10.1073/pnas.0701252104 [Abstract] [Full Text] [Figures Only] [PDF]  

Pharmacology

Joseph N. McLaughlin, Myla M. Patterson, and Asrar B. Malik

Protease-activated receptor-3 (PAR3) regulates PAR1 signaling by receptor dimerization
PNAS 2007 104: 5662-5667; published online before print March 21 2007, 10.1073/pnas.0700763104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Figure]  

Tomoyuki Miyabayashi, Jia-Ling Teo, Masashi Yamamoto, Michael McMillan, Cu Nguyen, and Michael Kahn

Wnt/-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency
PNAS 2007 104: 5668-5673; published online before print March 19 2007, 10.1073/pnas.0701331104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Physiology

Mark W. Sherwood, Ian A. Prior, Svetlana G. Voronina, Stephanie L. Barrow, Jonathan D. Woodsmith, Oleg V. Gerasimenko, Ole H. Petersen, and Alexei V. Tepikin

Activation of trypsinogen in large endocytic vacuoles of pancreatic acinar cells
PNAS 2007 104: 5674-5679; published online before print March 15 2007, 10.1073/pnas.0700951104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Jonathan B. Hurov, Mei Huang, Lynn S. White, Jochen Lennerz, Cheol Soo Choi, You-Ree Cho, Hyo-Jeong Kim, Julie L. Prior, David Piwnica-Worms, Lewis C. Cantley, Jason K. Kim, Gerald I. Shulman, and Helen Piwnica-Worms Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo PNAS 2007 104: 5680-5685; published online before print March 19 2007, 10.1073/pnas.0701179104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information] OPEN ACCESS ARTICLE

Plant Biology

Douglas Van Hoewyk, Salah E. Abdel-Ghany, Christopher M. Cohu, Stephen K. Herbert, Paul Kugrens, Marinus Pilon, and Elizabeth A. H. Pilon-Smits

Chloroplast iron-sulfur cluster protein maturation requires the essential cysteine desulfurase CpNifS
PNAS 2007 104: 5686-5691; published online before print March 19 2007, 10.1073/pnas.0700774104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Population Biology

Alison P. Galvani, Timothy C. Reluga, and Gretchen B. Chapman

Long-standing influenza vaccination policy is in accord with individual self-interest but not with the utilitarian optimum
PNAS 2007 104: 5692-5697; published online before print March 16 2007, 10.1073/pnas.0606774104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

Kerrin S. Small, Michael Brudno, Matthew M. Hill, and Arend Sidow

Extreme genomic variation in a natural population
PNAS 2007 104: 5698-5703; published online before print March 19 2007, 10.1073/pnas.0700890104 [Abstract] [Full Text] [Figures Only] [PDF] [Supporting Information]  

CORRECTIONS

Correction for Wuchter et al., Archaeal nitrification in the ocean [Full Text] [PDF]